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Posts with Citations

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Dear CNRS: That mouse study did not "confirm" the neurobiological origin of ADHD in humans
Late last week the French National Centre for Scientific Research (CNRS - the acronym is based on the French translation) put out a press release describing a study conducted through a collaboration between several of its researchers and scientists from The University of Strasbourg. CNRS is a large (30,000+ employees), government-run research institution in France. It is the largest research organization in Europe, and is responsible for about 1/2 of the French scientific papers published […]

Mathis, C., Savier, E., Bott, J., Clesse, D., Bevins, N., Sage-Ciocca, D., Geiger, K., Gillet, A., Laux-Biehlmann, A., Goumon, Y. & Lacaud, A. (2014). Defective response inhibition and collicular noradrenaline enrichment in mice with duplicated retinotopic map in the superior colliculus, Brain Structure and Function, DOI:

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Research on flies suggests that lost stem cells are naturally replaced by non-stem cells
Erika MatunisCreditJohns Hopkins researchers have discovered an unexpected phenomenon in the organs that produce sperm in fruit flies, when a certain kind of stem cell is killed off experimentally, another group of non-stem cells can come out of retirement to replace them.The discovery sheds light on the tiny "environments" that stem cells occupy in animal bodies and may help explain how stem cells in tumors replenish themselves, the researchers report in the May 8 issue of the journal Cell […]

Phylis Hétié, Margaret de Cuevas, Erika Matunis (2014). Conversion of Quiescent Niche Cells to Somatic Stem Cells Causes Ectopic Niche Formation in the Drosophila Testis, Cell Reports, Other: http://dx.doi.org/10.1016/j.celrep.2014.03.058

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Danish Project to Make Polymer Solar Cells More Profitable
Project Megawatt intends to make polymer solar cells profitable enough to allow power generation from polymer solar cells to compete on market terms with traditional coal-fired power plants. Read more »

Krebs, F., Espinosa, N., Hösel, M., Søndergaard, R. & Jørgensen, M. (2014). 25th Anniversary Article: Rise to Power - OPV-Based Solar Parks, Advanced Materials, 26 (1) 29-39. DOI:

Sommer-Larsen, P., Jørgensen, M., Søndergaard, R., Hösel, M. & Krebs, F. (2013). It is all in the Pattern-High-Efficiency Power Extraction from Polymer Solar Cells through High-Voltage Serial Connection, Energy Technology, 1 (1) 15-19. DOI:

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Mesenchymal stem cells require hydrogen sulfide to function properly
Professor Songtao ShiMesenchymal stem cells need to produce hydrogen sulfide in order to properly multiply and form bone tissue, according to a new study from the Center for Craniofacial Molecular Biology at the Ostrow School of Dentistry.Professor Songtao Shi, principal investigator on the project, said the presence of hydrogen sulfide produced by the cells governs the flow of calcium ions. The essential ions activate a chain of cellular signals that results in osteogenesis, or the creation of […]

Liu, Y., Yang, R., Liu, X., Zhou, Y., Qu, C., Kikuiri, T., Wang, S., Zandi, E., Du, J., Ambudkar, I. & Shi, S. (2014). Hydrogen Sulfide Maintains Mesenchymal Stem Cell Function and Bone Homeostasis via Regulation of Ca2+ Channel Sulfhydration, Cell Stem Cell, DOI:

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Li-Sulfur Batteries Last Longer With Metal-Organic Frameworks
Researchers at the PNNL added a kind of nanomaterial called a metal-organic framework, to the battery’s cathode to capture problematic polysulfides that usually cause lithium-sulfur batteries to fail after a few charges. Read more »

Zheng, J., Tian, J., Wu, D., Gu, M., Xu, W., Wang, C., Gao, F., Engelhard, M., Zhang, J., Liu, J. & Xiao, J. (2014). Lewis Acid–Base Interactions between Polysulfides and Metal Organic Framework in Lithium Sulfur Batteries, Nano Letters, 2147483647. DOI:

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Is It Good For Kids To Have A Pet?
People overwhelmingly believe that having pets is overall a good thing for children. Indeed, a 2003 paper by developmental psychologist Gail F. Melson reports that most parents say that they acquired... -- Read more on ScientificAmerican.com

Mueller M.K. (2014). Is Human-Animal Interaction (HAI) Linked to Positive Youth Development? Initial Answers, Applied Developmental Science, 18 (1) 5-16. DOI:

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What’s the Answer? (new Biostars interface)
BioStars is a site for asking, answering and discussing bioinformatics questions and issues. We are members of the community and find it very useful. Often questions and answers arise at BioStars that are germane to our readers (end users of genomics resources). Every Thursday we will be highlighting one of those items or discussions here […]

Parnell L.D., Lindenbaum P., Shameer K., Dall'Olio G.M., Swan D.C., Jensen L.J., Cockell S.J., Pedersen B.S., Mangan M.E. & Miller C.A. & (2011). BioStar: An Online Question & Answer Resource for the Bioinformatics Community, PLoS Computational Biology, 7 (10) e1002216. DOI:

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Cannabis use and structural changes in the brain
  “One or two spliffs a week could mess up your brain” – Metro, 16 April 2014 Spark your interest? This headline caught the eyes of the Antisense team, so […]

Gilman, J., Kuster, J., Lee, S., Lee, M., Kim, B., Makris, N., van der Kouwe, A., Blood, A. & Breiter, H. (2014). Cannabis Use Is Quantitatively Associated with Nucleus Accumbens and Amygdala Abnormalities in Young Adult Recreational Users, Journal of Neuroscience, 34 (16) 5529-5538. DOI:

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Modified stem cells may offer treatment for Alzheimer's disease
Mathew Blurton-JonesUC Irvine neurobiologists have found that genetically modified neural stem cells show positive results when transplanted into the brains of mice with the symptoms and pathology of Alzheimer's disease. The pre-clinical trial is published in the journal Stem Cells Research and Therapy, and the approach has been shown to work in two different mouse models.Alzheimer's disease, one of the most common forms of dementia, is associated with accumulation of the protein amyloid-beta […]

Blurton-Jones, M., Spencer, B., Michael, S., Castello, N., Agazaryan, A., Davis, J., Müller, F., Loring, J., Masliah, E. & LaFerla, F. & (2014). Neural stem cells genetically-modified to express neprilysin reduce pathology in Alzheimer transgenic models, Stem Cell Research & Therapy, 5 (2) 46. DOI:

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Mitochondrial dysfunction as a neurobiological subtype of autism
The paper by Suzanne Goh and colleagues [1] reporting on "a possible neurobiological subtype of mitochondrial dysfunction in ASD [autism spectrum disorder]" is a worthy addition to the research roll call which has graced this blog down the years. Based on the analysis of brain lactate levels - a potential marker of mitochondrial dysfunction - via the analysis of lactate doublets on brain magnetic resonance spectroscopic imaging (MRSI), authors picked up a significantly higher rate of […]

Goh, S., Dong, Z., Zhang, Y., DiMauro, S. & Peterson, B. (2014). Mitochondrial Dysfunction as a Neurobiological Subtype of Autism Spectrum Disorder, JAMA Psychiatry, DOI:

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