Posts

July 31, 2014

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5:33 PM | Mitochondria and Anti Aging
I’m sure you can all relate, you go to fix the sink and in the process you build a new kitchen on accident. Anyone… no? Well that is sort of […]

Lisanti, S., Tavecchio, M., Chae, Y., Liu, Q., Brice, A., Thakur, M., Languino, L. & Altieri, D. (2014). Deletion of the Mitochondrial Chaperone TRAP-1 Uncovers Global Reprogramming of Metabolic Networks, Cell Reports, DOI: 10.1016/j.celrep.2014.06.061

Citation
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5:33 PM | Mitochondria and Anti Aging
I’m sure you can all relate, you go to fix the sink and in the process you build a new kitchen on accident. Anyone… no? Well that is sort of […]

Lisanti, S., Tavecchio, M., Chae, Y., Liu, Q., Brice, A., Thakur, M., Languino, L. & Altieri, D. (2014). Deletion of the Mitochondrial Chaperone TRAP-1 Uncovers Global Reprogramming of Metabolic Networks, Cell Reports, DOI: 10.1016/j.celrep.2014.06.061

Citation
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4:06 AM | Practice & the tenure question
I feel odd weighing in here, because I have actively not joined the conversation on twitter.  Between a conference, putting one project to bed and ramping another one up – I knew that I would not be able to keep up there so I consciously stayed away.  And I also knew that I needed some […]

July 30, 2014

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10:45 PM | Keeping lithium contained: new design allows for high energy-density anode in Li-ion batteries
Lithium ion batteries – they’re everywhere, and their name has become mainstream enough that non-scientists know they’re in our laptops and electronics.  These types of batteries are so popular because lithium boasts a high energy density and they don’t lose charge … Continue reading →

Zheng, G., Lee, S., Liang, Z., Lee, H., Yan, K., Yao, H., Wang, H., Li, W., Chu, S. & Cui, Y. & (2014). Interconnected hollow carbon nanospheres for stable lithium metal anodes, Nature Nanotechnology, DOI: 10.1038/nnano.2014.152

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5:31 PM | Suicide, it might be in the blood
I tried to kill myself, more than once in fact. It was a troubling time for me and as a former active duty Marine that might not be too surprising […]

Guintivano, J., Brown, T., Newcomer, A., Jones, M., Cox, O., Maher, B., Eaton, W., Payne, J., Wilcox, H. & Kaminsky, Z. & (2014). Identification and Replication of a Combined Epigenetic and Genetic Biomarker Predicting Suicide and Suicidal Behaviors, American Journal of Psychiatry, DOI: 10.1176/appi.ajp.2014.14010008

Guintivano, J., Arad, M., Gould, T., Payne, J. & Kaminsky, Z. (2013). Antenatal prediction of postpartum depression with blood DNA methylation biomarkers, Molecular Psychiatry, 19 (5) 560-567. DOI: 10.1038/mp.2013.62

Citation
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5:31 PM | Suicide, it might be in the blood
I tried to kill myself, more than once in fact. It was a troubling time for me and as a former active duty Marine that might not be too surprising […]

Guintivano, J., Brown, T., Newcomer, A., Jones, M., Cox, O., Maher, B., Eaton, W., Payne, J., Wilcox, H. & Kaminsky, Z. & (2014). Identification and Replication of a Combined Epigenetic and Genetic Biomarker Predicting Suicide and Suicidal Behaviors, American Journal of Psychiatry, DOI: 10.1176/appi.ajp.2014.14010008

Guintivano, J., Arad, M., Gould, T., Payne, J. & Kaminsky, Z. (2013). Antenatal prediction of postpartum depression with blood DNA methylation biomarkers, Molecular Psychiatry, 19 (5) 560-567. DOI: 10.1038/mp.2013.62

Citation
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5:31 PM | Suicide, it might be in the blood
I tried to kill myself, more than once in fact. It was a troubling time for me and as a former active duty Marine that might not be too surprising […]

Guintivano, J., Brown, T., Newcomer, A., Jones, M., Cox, O., Maher, B., Eaton, W., Payne, J., Wilcox, H. & Kaminsky, Z. & (2014). Identification and Replication of a Combined Epigenetic and Genetic Biomarker Predicting Suicide and Suicidal Behaviors, American Journal of Psychiatry, DOI: 10.1176/appi.ajp.2014.14010008

Guintivano, J., Arad, M., Gould, T., Payne, J. & Kaminsky, Z. (2013). Antenatal prediction of postpartum depression with blood DNA methylation biomarkers, Molecular Psychiatry, 19 (5) 560-567. DOI: 10.1038/mp.2013.62

Citation
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5:31 PM | Suicide, it might be in the blood
I tried to kill myself, more than once in fact. It was a troubling time for me and as a former active duty Marine that might not be too surprising […]

Guintivano, J., Brown, T., Newcomer, A., Jones, M., Cox, O., Maher, B., Eaton, W., Payne, J., Wilcox, H. & Kaminsky, Z. & (2014). Identification and Replication of a Combined Epigenetic and Genetic Biomarker Predicting Suicide and Suicidal Behaviors, American Journal of Psychiatry, DOI: 10.1176/appi.ajp.2014.14010008

Guintivano, J., Arad, M., Gould, T., Payne, J. & Kaminsky, Z. (2013). Antenatal prediction of postpartum depression with blood DNA methylation biomarkers, Molecular Psychiatry, 19 (5) 560-567. DOI: 10.1038/mp.2013.62

Citation
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4:00 PM | Oh, Rats! They’ll Regret This.
We often find ourselves in decision-making dilemmas along the day. For instance, to reach work on time, would you rather take the shorter, faster route or the longer, scenic route? In deciding these actions, the brain promptly fits in a reward versus risk equation, but sometimes the outcome isn’t quite favorable! What if there was … Continue reading →

Steiner A.P. (2014). Behavioral and neurophysiological correlates of regret in rat decision-making on a neuroeconomic task, Nature Neuroscience, 17 (7) 995-1002. DOI: http://dx.doi.org/10.1038/nn.3740

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2:46 PM | Influenza: How the Great War helped create the greatest pandemic the world has ever known | @GrrlScientist
The Great War helped create the influenza pandemic of 1918, which eventually brought an early end to the Great War.I had a little bird,Its name was Enza. I opened the window,And in-flu-enza. ~ Children's Skipping Rhyme, 1918 Like most rhymes that one learns as a child, I had no idea at the time what this one meant, nor did I ponder its possible meaning as I grew older. But one afternoon, this poem's significance became startlingly clear to me. As I sat in a large university lecture hall where […]

Taubenberger J.K. (2006). 1918 Influenza: the Mother of All Pandemics, Emerging Infectious Diseases, 12 (1) 15-22. DOI: http://dx.doi.org/10.3201/eid1201.050979

Gamblin S.J. (2004). The Structure and Receptor Binding Properties of the 1918 Influenza Hemagglutinin, Science, 303 (5665) 1838-1842. DOI: http://dx.doi.org/10.1126/science.1093155

Barry J.M. (2004). The site of origin of the 1918 influenza pandemic and its public health implications (Commentary), Journal of Translational Medicine, 2 (3) DOI: 10.1186/1479-5876-2-3

Humphries M.O. (2014). Paths of Infection: The First World War and the Origins of the 1918 Influenza Pandemic, War in History, 21 (1) 55-81. DOI: http://dx.doi.org/10.1177/0968344513504525

Osterholm M.T. (2005). Preparing for the Next Pandemic, New England Journal of Medicine, 352 1839-1842. DOI: 10.1056/NEJMp058068

Citation
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2:46 PM | Influenza: How the Great War helped create the greatest pandemic the world has ever known | @GrrlScientist
The Great War helped create the influenza pandemic of 1918, which eventually brought an early end to the Great War.I had a little bird,Its name was Enza. I opened the window,And in-flu-enza. ~ Children's Skipping Rhyme, 1918 Like most rhymes that one learns as a child, I had no idea at the time what this one meant, nor did I ponder its possible meaning as I grew older. But one afternoon, this poem's significance became startlingly clear to me. As I sat in a large university lecture hall where […]

Taubenberger J.K. (2006). 1918 Influenza: the Mother of All Pandemics, Emerging Infectious Diseases, 12 (1) 15-22. DOI: http://dx.doi.org/10.3201/eid1201.050979

Gamblin S.J. (2004). The Structure and Receptor Binding Properties of the 1918 Influenza Hemagglutinin, Science, 303 (5665) 1838-1842. DOI: http://dx.doi.org/10.1126/science.1093155

Barry J.M. (2004). The site of origin of the 1918 influenza pandemic and its public health implications (Commentary), Journal of Translational Medicine, 2 (3) DOI: 10.1186/1479-5876-2-3

Humphries M.O. (2014). Paths of Infection: The First World War and the Origins of the 1918 Influenza Pandemic, War in History, 21 (1) 55-81. DOI: http://dx.doi.org/10.1177/0968344513504525

Osterholm M.T. (2005). Preparing for the Next Pandemic, New England Journal of Medicine, 352 1839-1842. DOI: 10.1056/NEJMp058068

Citation
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2:46 PM | Influenza: How the Great War helped create the greatest pandemic the world has ever known | @GrrlScientist
The Great War helped create the influenza pandemic of 1918, which eventually brought an early end to the Great War.I had a little bird,Its name was Enza. I opened the window,And in-flu-enza. ~ Children's Skipping Rhyme, 1918 Like most rhymes that one learns as a child, I had no idea at the time what this one meant, nor did I ponder its possible meaning as I grew older. But one afternoon, this poem's significance became startlingly clear to me. As I sat in a large university lecture hall where […]

Taubenberger J.K. (2006). 1918 Influenza: the Mother of All Pandemics, Emerging Infectious Diseases, 12 (1) 15-22. DOI: http://dx.doi.org/10.3201/eid1201.050979

Gamblin S.J. (2004). The Structure and Receptor Binding Properties of the 1918 Influenza Hemagglutinin, Science, 303 (5665) 1838-1842. DOI: http://dx.doi.org/10.1126/science.1093155

Barry J.M. (2004). The site of origin of the 1918 influenza pandemic and its public health implications (Commentary), Journal of Translational Medicine, 2 (3) DOI: 10.1186/1479-5876-2-3

Humphries M.O. (2014). Paths of Infection: The First World War and the Origins of the 1918 Influenza Pandemic, War in History, 21 (1) 55-81. DOI: http://dx.doi.org/10.1177/0968344513504525

Osterholm M.T. (2005). Preparing for the Next Pandemic, New England Journal of Medicine, 352 1839-1842. DOI: 10.1056/NEJMp058068

Citation

July 29, 2014

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5:15 PM | Can’t Handle the Stress? Blame your Brain
Do you rise to the occasion, or do you fold under the pressure? No matter which side of the fence you’re, you can thank [or blame] your brain. Some people […]

Kumar, S., Hultman, R., Hughes, D., Michel, N., Katz, B. & Dzirasa, K. (2014). Prefrontal cortex reactivity underlies trait vulnerability to chronic social defeat stress, Nature Communications, 5 DOI: 10.1038/ncomms5537

Citation
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5:15 PM | Can’t Handle the Stress? Blame your Brain
Do you rise to the occasion, or do you fold under the pressure? No matter which side of the fence you’re, you can thank [or blame] your brain. Some people […]

Kumar, S., Hultman, R., Hughes, D., Michel, N., Katz, B. & Dzirasa, K. (2014). Prefrontal cortex reactivity underlies trait vulnerability to chronic social defeat stress, Nature Communications, 5 DOI: 10.1038/ncomms5537

Citation
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5:15 PM | Can’t Handle the Stress? Blame your Brain
Do you rise to the occasion, or do you fold under the pressure? No matter which side of the fence you’re, you can thank [or blame] your brain. Some people […]

Kumar, S., Hultman, R., Hughes, D., Michel, N., Katz, B. & Dzirasa, K. (2014). Prefrontal cortex reactivity underlies trait vulnerability to chronic social defeat stress, Nature Communications, 5 DOI: 10.1038/ncomms5537

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4:19 PM | A simple and useable classification of software by Aral Balkan via Wuthering Bytes
It’s getting pretty hard to do anything these days that doesn’t involve software. Our governments, businesses, laboratories, personal lives and entertainment would look very different without the software that makes them tick. How can we classify all this software to make sense of it all? The likes of this huge list of software categories on wikipedia are pretty […]

Malone, J., Brown, A., Lister, A., Ison, J., Hull, D., Parkinson, H. & Stevens, R. (2014). The Software Ontology (SWO): a resource for reproducibility in biomedical data analysis, curation and digital preservation, Journal of Biomedical Semantics, 5 (1) 25. DOI: 10.1186/2041-1480-5-25

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July 28, 2014

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5:13 PM | A New Hepatitis C Treatment offers Hope
Well this might seem weird, but today is world hepatitis day. I guess I should qualify weird with the fact that it’s only weird because no one really knows. What […]

Lawitz, E., Sulkowski, M., Ghalib, R., Rodriguez-Torres, M., Younossi, Z., Corregidor, A., DeJesus, E., Pearlman, B., Rabinovitz, M., Gitlin, N. & Lim, J. (2014). Simeprevir plus sofosbuvir, with or without ribavirin, to treat chronic infection with hepatitis C virus genotype 1 in non-responders to pegylated interferon and ribavirin and treatment-naive patients: the COSMOS randomised study, The Lancet, DOI: 10.1016/S0140-6736(14)61036-9

Citation
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5:13 PM | A New Hepatitis C Treatment offers Hope
Well this might seem weird, but today is world hepatitis day. I guess I should qualify weird with the fact that it’s only weird because no one really knows. What […]

Lawitz, E., Sulkowski, M., Ghalib, R., Rodriguez-Torres, M., Younossi, Z., Corregidor, A., DeJesus, E., Pearlman, B., Rabinovitz, M., Gitlin, N. & Lim, J. (2014). Simeprevir plus sofosbuvir, with or without ribavirin, to treat chronic infection with hepatitis C virus genotype 1 in non-responders to pegylated interferon and ribavirin and treatment-naive patients: the COSMOS randomised study, The Lancet, DOI: 10.1016/S0140-6736(14)61036-9

Citation
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5:13 PM | A New Hepatitis C Treatment offers Hope
Well this might seem weird, but today is world hepatitis day. I guess I should qualify weird with the fact that it’s only weird because no one really knows. What […]

Lawitz, E., Sulkowski, M., Ghalib, R., Rodriguez-Torres, M., Younossi, Z., Corregidor, A., DeJesus, E., Pearlman, B., Rabinovitz, M., Gitlin, N. & Lim, J. (2014). Simeprevir plus sofosbuvir, with or without ribavirin, to treat chronic infection with hepatitis C virus genotype 1 in non-responders to pegylated interferon and ribavirin and treatment-naive patients: the COSMOS randomised study, The Lancet, DOI: 10.1016/S0140-6736(14)61036-9

Citation
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5:13 PM | A New Hepatitis C Treatment offers Hope
Well this might seem weird, but today is world hepatitis day. I guess I should qualify weird with the fact that it’s only weird because no one really knows. What […]

Lawitz, E., Sulkowski, M., Ghalib, R., Rodriguez-Torres, M., Younossi, Z., Corregidor, A., DeJesus, E., Pearlman, B., Rabinovitz, M., Gitlin, N. & Lim, J. (2014). Simeprevir plus sofosbuvir, with or without ribavirin, to treat chronic infection with hepatitis C virus genotype 1 in non-responders to pegylated interferon and ribavirin and treatment-naive patients: the COSMOS randomised study, The Lancet, DOI: 10.1016/S0140-6736(14)61036-9

Citation

July 27, 2014

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6:17 PM | Holy Grail of Battery Design: A lithium anode
Technology has been racing forward at an ever increasing rate. Unfortunately, anyone who owns a smartphone will tell you that the battery life doesn’t match the advancements. That is probably […]

Liu N, Lu Z, Zhao J, McDowell MT, Lee HW, Zhao W & Cui Y (2014). A pomegranate-inspired nanoscale design for large-volume-change lithium battery anodes., Nature nanotechnology, 9 (3) 187-92. PMID: http://www.ncbi.nlm.nih.gov/pubmed/24531496

Citation
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6:17 PM | Holy Grail of Battery Design: A lithium anode
Technology has been racing forward at an ever increasing rate. Unfortunately, anyone who owns a smartphone will tell you that the battery life doesn’t match the advancements. That is probably […]

Liu N, Lu Z, Zhao J, McDowell MT, Lee HW, Zhao W & Cui Y (2014). A pomegranate-inspired nanoscale design for large-volume-change lithium battery anodes., Nature nanotechnology, 9 (3) 187-92. PMID: http://www.ncbi.nlm.nih.gov/pubmed/24531496

Citation
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6:17 PM | Holy Grail of Battery Design: A lithium anode
Technology has been racing forward at an ever increasing rate. Unfortunately, anyone who owns a smartphone will tell you that the battery life doesn’t match the advancements. That is probably […]

Liu N, Lu Z, Zhao J, McDowell MT, Lee HW, Zhao W & Cui Y (2014). A pomegranate-inspired nanoscale design for large-volume-change lithium battery anodes., Nature nanotechnology, 9 (3) 187-92. PMID: http://www.ncbi.nlm.nih.gov/pubmed/24531496

Citation
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6:17 PM | Holy Grail of Battery Design: A lithium anode
Technology has been racing forward at an ever increasing rate. Unfortunately, anyone who owns a smartphone will tell you that the battery life doesn’t match the advancements. That is probably […]

Liu N, Lu Z, Zhao J, McDowell MT, Lee HW, Zhao W & Cui Y (2014). A pomegranate-inspired nanoscale design for large-volume-change lithium battery anodes., Nature nanotechnology, 9 (3) 187-92. PMID: http://www.ncbi.nlm.nih.gov/pubmed/24531496

Citation
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6:17 PM | Holy Grail of Battery Design: A lithium anode
Technology has been racing forward at an ever increasing rate. Unfortunately, anyone who owns a smartphone will tell you that the battery life doesn’t match the advancements. That is probably […]

Liu N, Lu Z, Zhao J, McDowell MT, Lee HW, Zhao W & Cui Y (2014). A pomegranate-inspired nanoscale design for large-volume-change lithium battery anodes., Nature nanotechnology, 9 (3) 187-92. PMID: http://www.ncbi.nlm.nih.gov/pubmed/24531496

Citation

July 26, 2014

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5:18 PM | Save the Neurons: Fighting the Effects of Parkinsons
Possibly one of the most famous cases of parkinson’s is Michael J. Fox. More than just the “shakes” parkinson’s can cause a whole host of other problems mentally and physically […]

Barnum CJ, Chen X, Chung J, Chang J, Williams M, Grigoryan N, Tesi RJ & Tansey MG (2014). Peripheral Administration of the Selective Inhibitor of Soluble Tumor Necrosis Factor (TNF) XPro1595 Attenuates Nigral Cell Loss and Glial Activation in 6-OHDA Hemiparkinsonian Rats., Journal of Parkinson's disease, PMID: http://www.ncbi.nlm.nih.gov/pubmed/25061061

Citation
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5:18 PM | Save the Neurons: Fighting the Effects of Parkinsons
Possibly one of the most famous cases of parkinson’s is Michael J. Fox. More than just the “shakes” parkinson’s can cause a whole host of other problems mentally and physically […]

Barnum CJ, Chen X, Chung J, Chang J, Williams M, Grigoryan N, Tesi RJ & Tansey MG (2014). Peripheral Administration of the Selective Inhibitor of Soluble Tumor Necrosis Factor (TNF) XPro1595 Attenuates Nigral Cell Loss and Glial Activation in 6-OHDA Hemiparkinsonian Rats., Journal of Parkinson's disease, PMID: http://www.ncbi.nlm.nih.gov/pubmed/25061061

Citation
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5:18 PM | Save the Neurons: Fighting the Effects of Parkinsons
Possibly one of the most famous cases of parkinson’s is Michael J. Fox. More than just the “shakes” parkinson’s can cause a whole host of other problems mentally and physically […]

Barnum CJ, Chen X, Chung J, Chang J, Williams M, Grigoryan N, Tesi RJ & Tansey MG (2014). Peripheral Administration of the Selective Inhibitor of Soluble Tumor Necrosis Factor (TNF) XPro1595 Attenuates Nigral Cell Loss and Glial Activation in 6-OHDA Hemiparkinsonian Rats., Journal of Parkinson's disease, PMID: http://www.ncbi.nlm.nih.gov/pubmed/25061061

Citation
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5:18 PM | Save the Neurons: Fighting the Effects of Parkinsons
Possibly one of the most famous cases of parkinson’s is Michael J. Fox. More than just the “shakes” parkinson’s can cause a whole host of other problems mentally and physically […]

Barnum CJ, Chen X, Chung J, Chang J, Williams M, Grigoryan N, Tesi RJ & Tansey MG (2014). Peripheral Administration of the Selective Inhibitor of Soluble Tumor Necrosis Factor (TNF) XPro1595 Attenuates Nigral Cell Loss and Glial Activation in 6-OHDA Hemiparkinsonian Rats., Journal of Parkinson's disease, PMID: http://www.ncbi.nlm.nih.gov/pubmed/25061061

Citation
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5:18 PM | Save the Neurons: Fighting the Effects of Parkinsons
Possibly one of the most famous cases of parkinson’s is Michael J. Fox. More than just the “shakes” parkinson’s can cause a whole host of other problems mentally and physically […]

Barnum CJ, Chen X, Chung J, Chang J, Williams M, Grigoryan N, Tesi RJ & Tansey MG (2014). Peripheral Administration of the Selective Inhibitor of Soluble Tumor Necrosis Factor (TNF) XPro1595 Attenuates Nigral Cell Loss and Glial Activation in 6-OHDA Hemiparkinsonian Rats., Journal of Parkinson's disease, PMID: http://www.ncbi.nlm.nih.gov/pubmed/25061061

Citation
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