Posts

July 31, 2014

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5:33 PM | Mitochondria and Anti Aging
I’m sure you can all relate, you go to fix the sink and in the process you build a new kitchen on accident. Anyone… no? Well that is sort of […]

Lisanti, S., Tavecchio, M., Chae, Y., Liu, Q., Brice, A., Thakur, M., Languino, L. & Altieri, D. (2014). Deletion of the Mitochondrial Chaperone TRAP-1 Uncovers Global Reprogramming of Metabolic Networks, Cell Reports, DOI: 10.1016/j.celrep.2014.06.061

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July 30, 2014

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10:45 PM | Keeping lithium contained: new design allows for high energy-density anode in Li-ion batteries
Lithium ion batteries – they’re everywhere, and their name has become mainstream enough that non-scientists know they’re in our laptops and electronics.  These types of batteries are so popular because lithium boasts a high energy density and they don’t lose charge … Continue reading →

Zheng, G., Lee, S., Liang, Z., Lee, H., Yan, K., Yao, H., Wang, H., Li, W., Chu, S. & Cui, Y. & (2014). Interconnected hollow carbon nanospheres for stable lithium metal anodes, Nature Nanotechnology, DOI: 10.1038/nnano.2014.152

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9:22 PM | 3D Fractals ^_^
I my last post I told you that in Stuttgart at HFT we had an interesting presentation of some nice fractals in 3D, so I decided to Google it to find some nice photos, and I found THIS. Absolutely wonderful things, I … Continue reading →
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5:31 PM | Suicide, it might be in the blood
I tried to kill myself, more than once in fact. It was a troubling time for me and as a former active duty Marine that might not be too surprising […]

Guintivano, J., Brown, T., Newcomer, A., Jones, M., Cox, O., Maher, B., Eaton, W., Payne, J., Wilcox, H. & Kaminsky, Z. & (2014). Identification and Replication of a Combined Epigenetic and Genetic Biomarker Predicting Suicide and Suicidal Behaviors, American Journal of Psychiatry, DOI: 10.1176/appi.ajp.2014.14010008

Guintivano, J., Arad, M., Gould, T., Payne, J. & Kaminsky, Z. (2013). Antenatal prediction of postpartum depression with blood DNA methylation biomarkers, Molecular Psychiatry, 19 (5) 560-567. DOI: 10.1038/mp.2013.62

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5:31 PM | Suicide, it might be in the blood
I tried to kill myself, more than once in fact. It was a troubling time for me and as a former active duty Marine that might not be too surprising […]

Guintivano, J., Brown, T., Newcomer, A., Jones, M., Cox, O., Maher, B., Eaton, W., Payne, J., Wilcox, H. & Kaminsky, Z. & (2014). Identification and Replication of a Combined Epigenetic and Genetic Biomarker Predicting Suicide and Suicidal Behaviors, American Journal of Psychiatry, DOI: 10.1176/appi.ajp.2014.14010008

Guintivano, J., Arad, M., Gould, T., Payne, J. & Kaminsky, Z. (2013). Antenatal prediction of postpartum depression with blood DNA methylation biomarkers, Molecular Psychiatry, 19 (5) 560-567. DOI: 10.1038/mp.2013.62

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4:00 PM | Oh, Rats! They’ll Regret This.
We often find ourselves in decision-making dilemmas along the day. For instance, to reach work on time, would you rather take the shorter, faster route or the longer, scenic route? In deciding these actions, the brain promptly fits in a reward versus risk equation, but sometimes the outcome isn’t quite favorable! What if there was … Continue reading →

Steiner A.P. (2014). Behavioral and neurophysiological correlates of regret in rat decision-making on a neuroeconomic task, Nature Neuroscience, 17 (7) 995-1002. DOI: http://dx.doi.org/10.1038/nn.3740

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2:46 PM | Influenza: How the Great War helped create the greatest pandemic the world has ever known | @GrrlScientist
The Great War helped create the influenza pandemic of 1918, which eventually brought an early end to the Great War.I had a little bird,Its name was Enza. I opened the window,And in-flu-enza. ~ Children's Skipping Rhyme, 1918 Like most rhymes that one learns as a child, I had no idea at the time what this one meant, nor did I ponder its possible meaning as I grew older. But one afternoon, this poem's significance became startlingly clear to me. As I sat in a large university lecture hall where […]

Taubenberger J.K. (2006). 1918 Influenza: the Mother of All Pandemics, Emerging Infectious Diseases, 12 (1) 15-22. DOI: http://dx.doi.org/10.3201/eid1201.050979

Gamblin S.J. (2004). The Structure and Receptor Binding Properties of the 1918 Influenza Hemagglutinin, Science, 303 (5665) 1838-1842. DOI: http://dx.doi.org/10.1126/science.1093155

Barry J.M. (2004). The site of origin of the 1918 influenza pandemic and its public health implications (Commentary), Journal of Translational Medicine, 2 (3) DOI: 10.1186/1479-5876-2-3

Humphries M.O. (2014). Paths of Infection: The First World War and the Origins of the 1918 Influenza Pandemic, War in History, 21 (1) 55-81. DOI: http://dx.doi.org/10.1177/0968344513504525

Osterholm M.T. (2005). Preparing for the Next Pandemic, New England Journal of Medicine, 352 1839-1842. DOI: 10.1056/NEJMp058068

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2:46 PM | Influenza: How the Great War helped create the greatest pandemic the world has ever known | @GrrlScientist
The Great War helped create the influenza pandemic of 1918, which eventually brought an early end to the Great War.I had a little bird,Its name was Enza. I opened the window,And in-flu-enza. ~ Children's Skipping Rhyme, 1918 Like most rhymes that one learns as a child, I had no idea at the time what this one meant, nor did I ponder its possible meaning as I grew older. But one afternoon, this poem's significance became startlingly clear to me. As I sat in a large university lecture hall where […]

Taubenberger J.K. (2006). 1918 Influenza: the Mother of All Pandemics, Emerging Infectious Diseases, 12 (1) 15-22. DOI: http://dx.doi.org/10.3201/eid1201.050979

Gamblin S.J. (2004). The Structure and Receptor Binding Properties of the 1918 Influenza Hemagglutinin, Science, 303 (5665) 1838-1842. DOI: http://dx.doi.org/10.1126/science.1093155

Barry J.M. (2004). The site of origin of the 1918 influenza pandemic and its public health implications (Commentary), Journal of Translational Medicine, 2 (3) DOI: 10.1186/1479-5876-2-3

Humphries M.O. (2014). Paths of Infection: The First World War and the Origins of the 1918 Influenza Pandemic, War in History, 21 (1) 55-81. DOI: http://dx.doi.org/10.1177/0968344513504525

Osterholm M.T. (2005). Preparing for the Next Pandemic, New England Journal of Medicine, 352 1839-1842. DOI: 10.1056/NEJMp058068

Citation
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2:46 PM | Influenza: How the Great War helped create the greatest pandemic the world has ever known | @GrrlScientist
The Great War helped create the influenza pandemic of 1918, which eventually brought an early end to the Great War.I had a little bird,Its name was Enza. I opened the window,And in-flu-enza. ~ Children's Skipping Rhyme, 1918 Like most rhymes that one learns as a child, I had no idea at the time what this one meant, nor did I ponder its possible meaning as I grew older. But one afternoon, this poem's significance became startlingly clear to me. As I sat in a large university lecture hall where […]

Taubenberger J.K. (2006). 1918 Influenza: the Mother of All Pandemics, Emerging Infectious Diseases, 12 (1) 15-22. DOI: http://dx.doi.org/10.3201/eid1201.050979

Gamblin S.J. (2004). The Structure and Receptor Binding Properties of the 1918 Influenza Hemagglutinin, Science, 303 (5665) 1838-1842. DOI: http://dx.doi.org/10.1126/science.1093155

Barry J.M. (2004). The site of origin of the 1918 influenza pandemic and its public health implications (Commentary), Journal of Translational Medicine, 2 (3) DOI: 10.1186/1479-5876-2-3

Humphries M.O. (2014). Paths of Infection: The First World War and the Origins of the 1918 Influenza Pandemic, War in History, 21 (1) 55-81. DOI: http://dx.doi.org/10.1177/0968344513504525

Osterholm M.T. (2005). Preparing for the Next Pandemic, New England Journal of Medicine, 352 1839-1842. DOI: 10.1056/NEJMp058068

Citation
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1:00 PM | Seven Hours of Sleep May Be Better Than Eight
New research shows that 8 hours of sleep a night may not be the optimal amount for everyone.
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12:30 PM | The Attentive Look of a Dog in Training
Researchers investigate the body language of a dog that is performing well in training.Photo: Markus Balint / ShutterstockA new study puts dogs through the first stage of a basic training task and analyzes eye contact and posture in the most successful dogs. The research by Masashi Hasegawa et al (Azabu University School of Veterinary Medicine) is motivated by a desire to improve people’s training abilities by helping them recognize the posture associated with successful […]

Braem, M. & Mills, D. (2010). Factors affecting response of dogs to obedience instruction: A field and experimental study, Applied Animal Behaviour Science, 125 (1-2) 47-55. DOI: 10.1016/j.applanim.2010.03.004

Deldalle, S. & Gaunet, F. (2014). Effects of 2 training methods on stress-related behaviors of the dog (Canis familiaris) and on the dog–owner relationship, Journal of Veterinary Behavior: Clinical Applications and Research, 9 (2) 58-65. DOI: 10.1016/j.jveb.2013.11.004

Hasegawa, M., Ohtani, N. & Ohta, M. (2014). Dogs’ Body Language Relevant to Learning Achievement, Animals, 4 (1) 45-58. DOI: 10.3390/ani4010045

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2:27 AM | Science Blogging: Got Comments?
In a recent study of science bloggers, Merja Mahrt and Cornelius Puschmann found that the blog author very much influences the degree of commenting on his or her own blog posts. How? Through language complexity and topic selection. In a content analysis of over 200 posts at scienceblogs.com, researchblogging.org, hypotheses.org, amazings.es and scilogs.de (the German partner of SciLogs.com), these researchers found blog posts that received the most comments dealt either with common […]
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2:27 AM | Science Blogging: Got Comments?
In a recent study of science bloggers, Merja Mahrt and Cornelius Puschmann found that the blog author very much influences the degree of commenting on his or her own blog posts. How? Through language complexity and topic selection. In a content analysis of over 200 posts at scienceblogs.com, researchblogging.org, hypotheses.org, amazings.es and scilogs.de (the German partner of SciLogs.com), these researchers found blog posts that received the most comments dealt either with common […]
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2:27 AM | Science Blogging: Got Comments?
In a recent study of science bloggers, Merja Mahrt and Cornelius Puschmann found that the blog author very much influences the degree of commenting on his or her own blog posts. How? Through language complexity and topic selection. In a content analysis of over 200 posts at scienceblogs.com, researchblogging.org, hypotheses.org, amazings.es and scilogs.de (the German partner of SciLogs.com), these researchers found blog posts that received the most comments dealt either with common […]

July 29, 2014

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11:32 PM | A miniature turbine with blades one atom thick
Micro-machines, as well as being an awesome video game, are also a glimpse into the future (maybe): Some people believe that tiny robots could one day revolutionise medicine, while others think they might destroy the world in a big blob of ‘grey goo’. While fully-fledged nanorobots are currently limited to fictional universes such as those…

Li J., Lina Zhao, Xingfa Gao, Yuliang Zhao & Ruhong Zhou (2014). Rotation Motion of Designed Nano-Turbine, Scientific Reports, 4 DOI: http://dx.doi.org/10.1038/srep05846

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8:31 PM | The Impact of Pavlov’s Research Pavlov’s discovery...
The Impact of Pavlov’s Research Pavlov’s discovery of classical conditioning remains one of the most important in psychology’s history. In addition to forming the basis of what would become behavioral psychology, the conditioning process remains important today for numerous applications, including behavioral modification and mental health treatment. Classical conditioning is often used to treat phobias, anxiety and panic disorders. One interesting example of the practical use […]
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5:52 PM | Plants, polyploidy and producing new species
When I talk about my career and my interest in evolutionary biology, I often get asked, “How do you actually get new species?”. It’s not a stupid question; for people without a background in biology it really is very hard to imagine how the diversity of life we see today has formed from the types […]
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5:15 PM | Can’t Handle the Stress? Blame your Brain
Do you rise to the occasion, or do you fold under the pressure? No matter which side of the fence you’re, you can thank [or blame] your brain. Some people […]

Kumar, S., Hultman, R., Hughes, D., Michel, N., Katz, B. & Dzirasa, K. (2014). Prefrontal cortex reactivity underlies trait vulnerability to chronic social defeat stress, Nature Communications, 5 DOI: 10.1038/ncomms5537

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5:15 PM | Can’t Handle the Stress? Blame your Brain
Do you rise to the occasion, or do you fold under the pressure? No matter which side of the fence you’re, you can thank [or blame] your brain. Some people […]

Kumar, S., Hultman, R., Hughes, D., Michel, N., Katz, B. & Dzirasa, K. (2014). Prefrontal cortex reactivity underlies trait vulnerability to chronic social defeat stress, Nature Communications, 5 DOI: 10.1038/ncomms5537

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4:19 PM | A simple and useable classification of software by Aral Balkan via Wuthering Bytes
It’s getting pretty hard to do anything these days that doesn’t involve software. Our governments, businesses, laboratories, personal lives and entertainment would look very different without the software that makes them tick. How can we classify all this software to make sense of it all? The likes of this huge list of software categories on wikipedia are pretty […]

Malone, J., Brown, A., Lister, A., Ison, J., Hull, D., Parkinson, H. & Stevens, R. (2014). The Software Ontology (SWO): a resource for reproducibility in biomedical data analysis, curation and digital preservation, Journal of Biomedical Semantics, 5 (1) 25. DOI: 10.1186/2041-1480-5-25

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July 28, 2014

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5:13 PM | A New Hepatitis C Treatment offers Hope
Well this might seem weird, but today is world hepatitis day. I guess I should qualify weird with the fact that it’s only weird because no one really knows. What […]

Lawitz, E., Sulkowski, M., Ghalib, R., Rodriguez-Torres, M., Younossi, Z., Corregidor, A., DeJesus, E., Pearlman, B., Rabinovitz, M., Gitlin, N. & Lim, J. (2014). Simeprevir plus sofosbuvir, with or without ribavirin, to treat chronic infection with hepatitis C virus genotype 1 in non-responders to pegylated interferon and ribavirin and treatment-naive patients: the COSMOS randomised study, The Lancet, DOI: 10.1016/S0140-6736(14)61036-9

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5:13 PM | A New Hepatitis C Treatment offers Hope
Well this might seem weird, but today is world hepatitis day. I guess I should qualify weird with the fact that it’s only weird because no one really knows. What […]

Lawitz, E., Sulkowski, M., Ghalib, R., Rodriguez-Torres, M., Younossi, Z., Corregidor, A., DeJesus, E., Pearlman, B., Rabinovitz, M., Gitlin, N. & Lim, J. (2014). Simeprevir plus sofosbuvir, with or without ribavirin, to treat chronic infection with hepatitis C virus genotype 1 in non-responders to pegylated interferon and ribavirin and treatment-naive patients: the COSMOS randomised study, The Lancet, DOI: 10.1016/S0140-6736(14)61036-9

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5:13 PM | A New Hepatitis C Treatment offers Hope
Well this might seem weird, but today is world hepatitis day. I guess I should qualify weird with the fact that it’s only weird because no one really knows. What […]

Lawitz, E., Sulkowski, M., Ghalib, R., Rodriguez-Torres, M., Younossi, Z., Corregidor, A., DeJesus, E., Pearlman, B., Rabinovitz, M., Gitlin, N. & Lim, J. (2014). Simeprevir plus sofosbuvir, with or without ribavirin, to treat chronic infection with hepatitis C virus genotype 1 in non-responders to pegylated interferon and ribavirin and treatment-naive patients: the COSMOS randomised study, The Lancet, DOI: 10.1016/S0140-6736(14)61036-9

Citation
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5:13 PM | A New Hepatitis C Treatment offers Hope
Well this might seem weird, but today is world hepatitis day. I guess I should qualify weird with the fact that it’s only weird because no one really knows. What […]

Lawitz, E., Sulkowski, M., Ghalib, R., Rodriguez-Torres, M., Younossi, Z., Corregidor, A., DeJesus, E., Pearlman, B., Rabinovitz, M., Gitlin, N. & Lim, J. (2014). Simeprevir plus sofosbuvir, with or without ribavirin, to treat chronic infection with hepatitis C virus genotype 1 in non-responders to pegylated interferon and ribavirin and treatment-naive patients: the COSMOS randomised study, The Lancet, DOI: 10.1016/S0140-6736(14)61036-9

Citation

July 27, 2014

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11:06 PM | Magnificent Conotoxins – Expanded
“… if a small and otherwise unknown organism is strikingly beautiful, it is probably poisonous; if it is not only beautiful, but also easy to catch, it is probably deadly.” -Edward O.Wilson in: THE FUTURE OF LIFE Vintage Books, March 2003 The realm of proteins Proteins are probably the most versatile molecules within a living …
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9:32 PM | Second day
The second day (in Stuttgart) was more math than anything else, obviously. And it was mostly about industrial mathematics. First of all, I need to say that I was never attracted by these things, that seemed a little boring, but … Continue reading →
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6:17 PM | Holy Grail of Battery Design: A lithium anode
Technology has been racing forward at an ever increasing rate. Unfortunately, anyone who owns a smartphone will tell you that the battery life doesn’t match the advancements. That is probably […]

Liu N, Lu Z, Zhao J, McDowell MT, Lee HW, Zhao W & Cui Y (2014). A pomegranate-inspired nanoscale design for large-volume-change lithium battery anodes., Nature nanotechnology, 9 (3) 187-92. PMID: http://www.ncbi.nlm.nih.gov/pubmed/24531496

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6:17 PM | Holy Grail of Battery Design: A lithium anode
Technology has been racing forward at an ever increasing rate. Unfortunately, anyone who owns a smartphone will tell you that the battery life doesn’t match the advancements. That is probably […]

Liu N, Lu Z, Zhao J, McDowell MT, Lee HW, Zhao W & Cui Y (2014). A pomegranate-inspired nanoscale design for large-volume-change lithium battery anodes., Nature nanotechnology, 9 (3) 187-92. PMID: http://www.ncbi.nlm.nih.gov/pubmed/24531496

Citation
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6:17 PM | Holy Grail of Battery Design: A lithium anode
Technology has been racing forward at an ever increasing rate. Unfortunately, anyone who owns a smartphone will tell you that the battery life doesn’t match the advancements. That is probably […]

Liu N, Lu Z, Zhao J, McDowell MT, Lee HW, Zhao W & Cui Y (2014). A pomegranate-inspired nanoscale design for large-volume-change lithium battery anodes., Nature nanotechnology, 9 (3) 187-92. PMID: http://www.ncbi.nlm.nih.gov/pubmed/24531496

Citation
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6:17 PM | Holy Grail of Battery Design: A lithium anode
Technology has been racing forward at an ever increasing rate. Unfortunately, anyone who owns a smartphone will tell you that the battery life doesn’t match the advancements. That is probably […]

Liu N, Lu Z, Zhao J, McDowell MT, Lee HW, Zhao W & Cui Y (2014). A pomegranate-inspired nanoscale design for large-volume-change lithium battery anodes., Nature nanotechnology, 9 (3) 187-92. PMID: http://www.ncbi.nlm.nih.gov/pubmed/24531496

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