February 28, 2015

12:04 AM | ME/CFS is real: confirmation if it is needed...
"Scientists discover robust evidence that chronic fatigue syndrome is a biological illness" went the title of the press release for the study by Mady Hornig and colleagues [1] (open-access) detailing an immune 'signature' and also possible staging of the illness.I couldn't help but wince at some of the media headlines reporting on this study as 'proof' that chronic fatigue syndrome / myalgic encephalomyelitis (CFS/ME) is a real illness. As I've indicated before on this blog (see here) […]

Mady Hornig, José G. Montoya, Nancy G. Klimas, Susan Levine, Donna Felsenstein, Lucinda Bateman, Daniel L. Peterson, C. Gunnar Gottschalk, Andrew F. Schultz, Xiaoyu Che & Meredith L. Eddy (2015). Distinct plasma immune signatures in ME/CFS are present early in the course of illness, Science Advances, 1 (1) Other:


February 19, 2015

8:39 AM | Metal sensitisation and chronic fatigue syndrome?
I have to admit that I pondered longer than usual over whether I should talk about the paper by Vera Stejskal [1] (open-access here) and the idea that: "Patients with CFS [chronic fatigue syndrome] and fibromyalgia are frequently sensitized to metals found in the environment or used in dentistry and surgery."It was't that I doubted that metals - certain types present in the wrong place or wrong concentration - can affect physical and psychological health and wellbeing as per the […]

Stejskal V (2014). Metals as a common trigger of inflammation resulting in non-specific symptoms: diagnosis and treatment., The Israel Medical Association journal : IMAJ, 16 (12) 753-8. PMID:


February 10, 2015

9:09 PM | New name: Systemic Exertion Intolerance Disease?
The name is: Systematic Exertion Intolerance Disease (SEID).A very quick post to direct you to the public release of the findings from the US Institute of Medicine (IoM) looking at the name and current criteria used to diagnose Chronic Fatigue Syndrome / Myalgic Encephalomyelitis (CFS/ME) (see here). The proposed diagnostic criteria for CFS/ME, sorry SEID can be viewed here.Some of the background to these findings can be seen here and some of the media about the new IoM recommendations can […]

Morris G & Maes M (2013). Case definitions and diagnostic criteria for Myalgic Encephalomyelitis and Chronic fatigue Syndrome: from clinical-consensus to evidence-based case definitions., Neuro endocrinology letters, 34 (3) 185-99. PMID:

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