Posts
February 21, 2013
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7:21 PM | Myalgic encephalomyelitis (ME) and HERVs
Viruses. Apparently there are quite a lot of them on this old rock we call home and I've started to become quite interested in some of them, or at least how we as a species have, and continue to interact with them down the ages.I must start by thanking Natasa for bringing me into contact with the paper by Kenny De Meirleir and colleagues* (open-access) looking at human endogenous retrovirus (HERV) expression in a small cohort of patients diagnosed with myalgic encephalomyelitis (ME). I'm […]
KENNY L. DE MEIRLEIR, SVETLANA F. KHAIBOULLINA, MARC FRÉMONT, JAN HULSTAERT, ALBERT A. RIZVANOV, ANDRÁS PALOTÁS & VINCENT C. LOMBARDI (2013). Plasmacytoid dendritic cells in the duodenum of individuals diagnosed with myalgic encephalomyelitis are uniquely immunoreactive to antibodies to human endogenous retroviral proteins, In Vivo, 27 (2) 177-187. Other: Link
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November 28, 2012
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Consider this post a bit of a follow-up to a previous one based on some interesting observations by Booth and colleagues looking at mitochondrial dysfunction in cases of myalgic encephalomyelitis / chronic fatigue syndrome (ME/CFS).Join the Stone Age dots? @ Wikipedia Same authorship group but this time around presenting the results of an audit of patients who underwent examination based on the ATP profile (no endorsement given) and what they did about it published by Sarah
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Myhill S,, Booth NE, & McLaren-Howard J (2013). Targeting mitochondrial dysfunction in the treatment of Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) – a clinical audit, International Journal of Clinical & Experimental Medicine, 6 (1) 1-15. Other: Link
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October 08, 2012
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Vitamin D3 @ Wikipedia I have no hesitation in admitting to being more than a little bit "obsessive" about my data capture and the volumes of lovely, yummy science-y research alerts it produces. Indeed quite a bit of said research ends up as fodder for this and its sister blogs but most in the Twitter onslaught which my poor followers have to endure. Yes, I am probably addicted to information (but better this than other vices).One of my alerts is based on the various collected works […]
Berkovitz S, Ambler G, Jenkins M & Thurgood S (2009). Serum 25-hydroxy vitamin D levels in chronic fatigue syndrome: a retrospective survey., International journal for vitamin and nutrition research. Internationale Zeitschrift fur Vitamin- und Ernahrungsforschung. Journal international de vitaminologie et de nutrition, 79 (4) 250-4. PMID: 20209476
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July 16, 2012
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10:50 AM | Mitochondrial dysfunction and ME/CFS
I continue my interest in research examining chronic fatigue syndrome / myalgic encephalomyelitis (CFS/ME) in this post looking at what might turn out to be quite an important paper by Booth and colleagues* (full-text) on a potential role for mitochondrial dysfunction.Where to start....Mitochondria (plural) are not to be confused with the midi-chlorians of a Galaxy far, far away. A few associated words: organelles, eukaryotic cell, the power plant of cells, cellular respiration (this link […]
May 15, 2012
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Discussions on research pertaining to chronic fatigue syndrome / myalgic encephalomyelitis (CFS/ME) have appeared now and again on this blog. Whether it be in connection to diagnosis, or prevalence, or the very contentious topic of XMRV, CFS/ME research seems never to be far away from controversy (remembering also the PACE trial and a retort from a colleague of mine, Prof. Malcolm Hooper). While headlines abound about the conditions (notice the use of the plural), one has to […]
January 09, 2012
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I am ashamed to admit that 'wagging school' is something I did on more than one occasion as a teenager. It wasn't that I didn't like school or anything like that but some days I just couldn't face double maths or that sprightly cross country run over fields and mountains in the pouring rain that was PE. Don't get me wrong, I was no Ferris Bueller when it came to excuses and there was most certainly no 'Save Paul' campaign when I was absent from school. I might add that as a [supposedly] [...]
October 14, 2011
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9:33 PM | At least two sides to every story
This is a blog predominantly about autism research but now and again I have been known to wander. One topic which I wander off into quite a bit is Chronic Fatigue Syndrome (CFS) / Myalgic Encephalomyelitis (ME) as exemplified by posts like this and this. I wander into CFS/ME because, like autism, here is a spectrum of conditions asking more questions than answering them. One of the more 'heated' areas of questioning in CFS/ME has been around the various twists and turns of the XMRV [...]
September 24, 2011
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Have you ever played that game where, on a semi-sunny day, you lay on the grass eyes skywards and try and fit cloud shapes to objects or people? Y'know 'that cloud looks like a T-Rex dinosaur' or 'that cloud looks like my great Aunt Matilda walking the dog'. Your interpretation might often be shared with your compadres, but more often that not our individual perception and sensation makes others sit-up and question 'Eh?'Amongst the various descriptions, diagnoses and conditions discussed in [...]
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