Octopuses and their cephalopod cousins are the undisputed masters of disguise. An octopus can change its color, texture and luminosity faster than you can say “camouflage.” So far our...
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Missouri's governor has called in the National Guard, thanks to the current unrest in the city of Ferguson. Who makes up the National Guard and what exactly is it? Tara has the answers in this explainer.
The most recent issue of Science has two new reports on the so-called global warming hiatus and the carbon cycle in the Arctic, both of which are central to discussions of climate change and where temperature increases are being seen around … Continue reading →
Cory, R., Ward, C., Crump, B. & Kling, G. (2014). Sunlight controls water column processing of carbon in arctic fresh waters, Science, 345 (6199) 925-928. DOI: 10.1126/science.1253119
As an engineer you would think math would come easy to me, it didn’t. Funny thing though, science in general and biology in particular came very easy to me. The […]
Patrick T. Sadtler,, Kristin M. Quick,, Matthew D. Golub,, Steven M. Chase,, Stephen I. Ryu,, Elizabeth C. Tyler-Kabara,, Byron M. Yu, & Aaron P. Batista (2014). Neural constraints on learning, Nature, Other:
Development of the skeleton is a good example of a process that is highly regulated, requires a lot of precision, is conserved and important relationships across species, and is fairly easy to detect when it’s gone awry. I mean–it’s hard to know at a glance if all the neurons in an organism got to the […]
Mabee B.P., Balhoff J.P., Dahdul W.M., Lapp H., Midford P.E., Vision T.J. & Westerfield M. (2012). 500,000 fish phenotypes: The new informatics landscape for evolutionary and developmental biology of the vertebrate skeleton., Zeitschrift fur angewandte Ichthyologie = Journal of applied ichthyology, PMID: http://www.ncbi.nlm.nih.gov/pubmed/22736877
Balhoff J.P., Cartik R. Kothari, Hilmar Lapp, John G. Lundberg, Paula Mabee, Peter E. Midford, Monte Westerfield & Todd J. Vision (2010). Phenex: Ontological Annotation of Phenotypic Diversity, PLoS ONE, 5 (5) e10500. DOI: http://dx.doi.org/10.1371/journal.pone.0010500
Many centuries ago, human activity was believed to result in earthquakes – If we did not sufficiently appease the gods, mighty Tepeyollotl, heart of the mountains, would vent his calamitous rage with a terrifying, tumultuous upheaval of the earth itself. Nowadays most of us know better (although that still doesn’t stop some religious nuts from…
Mulargia, F. & Bizzarri, A. (2014). Anthropogenic Triggering of Large Earthquakes, Scientific Reports, 4 6100. DOI: 10.1038/srep06100
Chaperones aren't just for high-school homecoming dances. Cells have chaperones as well, chaperone proteins that ensure newly made proteins are properly folded. If protein folding goes awry, diseases associated with misfolded proteins such as Alzheimer's and Parkinson's can arise. But if one set of chaperones can throw a wet blanket on a school dance, imagine a second set of co-chaperones just to keep the chaperones in check. That's the growing picture in cellular chaperoning as folding
Rogon, C., Ulbricht, A., Hesse, M., Alberti, S., Vijayaraj, P., Best, D., Adams, I., Magin, T., Fleischmann, B. & Hohfeld, J. & (2014). HSP70-binding protein HSPBP1 regulates chaperone expression at a posttranslational level and is essential for spermatogenesis, Molecular Biology of the Cell, 25 (15) 2260-2271. DOI: 10.1091/mbc.E14-02-0742
Alberti S, Böhse K, Arndt V, Schmitz A, Höhfeld J. (2004). The Cochaperone HspBP1 Inhibits the CHIP Ubiquitin Ligase and Stimulates the Maturation of the Cystic Fibrosis Transmembrane Conductance Regulator, Molecular Biology of the Cell, 15 (9) 4003-4010. DOI: 10.1091/mbc.E04-04-0293