August 08, 2014

10:00 PM | Psychiatry and inflammation (again)
I'd like to bring two papers to your attention in today's very quick post."The Death Star plans are not in the main computer"First up is the article by Kahn & Sommer [1] (open-access) titled: 'The neurobiology and treatment of first-episode schizophrenia'. It's about as good a read as we have so far on the topic of "brain changes in the first phase of schizophrenia" and the various management options for first-episode schizophrenia. Outside of the very important fact that "It is highly […]

Kahn RS & Sommer IE (2014). The neurobiology and treatment of first-episode schizophrenia., Molecular psychiatry, PMID:

Friedrich MJ (2014). Research on Psychiatric Disorders Targets Inflammation., JAMA : the journal of the American Medical Association, PMID:


August 05, 2014

11:38 PM | Aspirin and cancer – not quite, but nearly
We discuss a new analysis of the pros and cons of taking regular aspirin, and ask 'what's next?'

August 04, 2014

8:10 AM | Stopping gliadin peptides in their tracks?
A micropost if you will, to bring to your attention the paper by Marco Sarno and colleagues [1] and their suggestion of "a novel effect of probiotics in the prevention of undigested gliadin peptides toxic effects".Knitting on't Moors @ Wikipedia The probiotic in question is something called Lactobacillus paracasei CBA L74, which if I'm not mistaken is connected with a certain '57 varieties' company. The authors (which included one Alessio Fasano) indicated that said probiotic […]

July 29, 2014

8:04 AM | Ketogenic diet and the valproate mouse model of autism
A brief entry today and yet another blog post that starts with a quote (sorry)... "The offspring exposed to VPA [valproic acid] prenatally demonstrated a significant decrease in the number of play initiations/attacks and this was reversed with the KD [ketogenic diet]".Gloucester Old Spot @ Wikipedia That finding reported in the paper by Ahn and colleagues [1] continues my interest in all-things related to prenatal VPA exposure and the reported effects on some offspring […]

July 25, 2014

5:06 PM | Anti-inflammatory drug prevents neuron loss in Parkinson’s model
Promising research recently published in Journal of Parkinson's Disease The post Anti-inflammatory drug prevents neuron loss in Parkinson’s model appeared first on Lab Land.

July 23, 2014

7:46 AM | Trauma and PTSD raise risk of autoimmune disorders?
I admit to some head scratching when I first read the paper by Aoife O’Donovan and colleagues [1] reporting that among war veterans of the Iraq and Afghanistan campaigns, "trauma exposure and PTSD [post-traumatic stress disorder] may increase risk of autoimmune disorders".It wasn't that I didn't believe the results, but rather that the idea that a physical event with a psychological consequence could impact on a somatic condition with an autoimmune element to it seemed to […]

O’Donovan, A., Cohen, B., Seal, K., Bertenthal, D., Margaretten, M., Nishimi, K. & Neylan, T. (2014). Elevated Risk For Autoimmune Disorders In Iraq And Afghanistan Veterans With Posttraumatic Stress Disorder, Biological Psychiatry, DOI: 10.1016/j.biopsych.2014.06.015


July 21, 2014

7:24 AM | Autism and asthma yet again
"Asthma is approximately 35 % more common in autistic children".Pipe down @ Wikipedia That was the finding reported by Stanley Kotey and colleagues [1] based on their analysis of the 2007 National Survey of Children's Health (NSCH) dataset, a resource looking at "the physical and emotional health of children ages 0-17 years of age" resident in the United States. I don't intend to dwell too much on the Kotey findings aside from pointing out: (a) the reported prevalence of autism […]

Kotey, S., Ertel, K. & Whitcomb, B. (2014). Co-occurrence of Autism and Asthma in a Nationally-Representative Sample of Children in the United States, Journal of Autism and Developmental Disorders, DOI: 10.1007/s10803-014-2174-y

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