October 17, 2014

9:22 AM | Altered ghrelin levels in boys with autism
"Honey, it's the '90s, remember?"Saudi Arabia and autism research? It must be at least one author from the research tag-team that is Mostafa and Al-Ayadhi.Indeed, in today's post it is Laila Al-Ayadhi featured on the paper by Felwah S. Al-Zaid and colleagues [1] (open-access) who concluded on: "a potential role for the hormone ghrelin in the pathogenesis of autism".Ghrelin, by the way, is often called the 'hunger hormone' as a result of its effects in relation to energy homoeostasis. […]

Al-Zaid FS, Alhader AA & Al-Ayadhi LY (2014). Altered ghrelin levels in boys with autism: a novel finding associated with hormonal dysregulation., Scientific reports, 4 6478. PMID:


October 11, 2014

8:48 AM | Yet more air pollution and autism risk research
Air pollution and autism risk. It's a topic which has cropped up a few times on this blog (see here and see here and see here) with the majority of the research (but not all) suggesting that there may be something to see when it comes to such a correlation.Enter then the paper by Amy Kalkbrenner and colleagues [1] to proceedings, and their conclusion: "Our study adds to previous work in California showing a relation between traffic-related air pollution and autism, and adds similar findings in […]

Kalkbrenner AE, Windham GC, Serre ML, Akita Y, Wang X, Hoffman K, Thayer BP & Daniels JL (2014). Particulate Matter Exposure, Prenatal and Postnatal Windows of Susceptibility, and Autism Spectrum Disorders., Epidemiology (Cambridge, Mass.), PMID:


October 07, 2014

9:02 AM | Infection during pregnancy and offspring autism risk
The paper by Lee and colleagues [1] forms the starting material for today's blog post looking at hospitalisation for infection during pregnancy as potentially being a risk factor for receipt of a subsequent diagnosis for autism in offspring."Chaos is what killed the dinosaurs, darling"Based on data derived from one of those very useful Scandinavian health registries, authors observed "approximately a 30% increase in ASD [autism spectrum disorder] risk associated with any inpatient […]

Lee BK, Magnusson C, Gardner RM, Blomström S, Newschaffer CJ, Burstyn I, Karlsson H & Dalman C (2014). Maternal hospitalization with infection during pregnancy and risk of autism spectrum disorders., Brain, behavior, and immunity, PMID:

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