November 15, 2014

9:40 AM | Milk has gotta lotta bottle?
"High milk intake was associated with higher mortality in one cohort of women and in another cohort of men, and with higher fracture incidence in women". Those were some of the conclusions reached in the study by Karl Michaëlsson and colleagues [1] (open-access) looking at milk consumption and "mortality and fractures in women and men". The BBC among other media have covered the study (see here).Take me out tonightBased on quite a large participant group (two actually) who completed a […]

Michaelsson, K., Wolk, A., Langenskiold, S., Basu, S., Warensjo Lemming, E., Melhus, H. & Byberg, L. (2014). Milk intake and risk of mortality and fractures in women and men: cohort studies, BMJ, 349 (oct27 1) DOI: 10.1136/bmj.g6015


November 12, 2014

9:53 AM | An inflammatory autism subtype?
The paper from Harumi Jyonouchi and colleagues [1] (open-access) continues a theme from this author with their suggestion of "an imbalance in the production of inflammatory (IL-1ß and IL-6) and counterregulatory (IL-10) cytokines by ‘flare’ ASD-IS [autism spectrum disorder - inflammatory subtype] monocytes".Panic on the streets of Birmingham...'Flare' ASD-IS in this case refers to a coding given to a small participant group (n=24) who were: "defined as those […]

November 07, 2014

9:11 AM | Treating depression: exercise or anti-inflammatory meds?
Reiterating my primary caveat on this blog about not giving anything that looks, sounds or smells like medical and/or clinical advice, I'm bringing three papers to the research blogging table today, all published in the JAMA journal family and all talking about depression / depressive symptoms.See my hat... @ Wikipedia First up is the paper by Ole Köhler and colleagues [1] reviewing "the antidepressant and possible adverse effects of anti-inflammatory interventions". Some […]

Ole Köhler, Michael E. Benros, Merete Nordentoft, Michael E. Farkouh, Rupa L. Iyengar, Ole Mors & Jesper Krogh (2014). Effect of Anti-inflammatory Treatment on Depression, Depressive Symptoms, and Adverse Effects, JAMA Psychiatry, Other:

Snehal M. Pinto Pereira, Marie-Claude Geoffroy & Christine Power (2014). Depressive Symptoms and Physical Activity During 3 Decades in Adult Life, JAMA Psychiatry, Other:

Toseeb, U., Brage, S., Corder, K., Dunn, V., Jones, P., Owens, M., St Clair, M., van Sluijs, E. & Goodyer, I. (2014). Exercise and Depressive Symptoms in Adolescents, JAMA Pediatrics, DOI: 10.1001/jamapediatrics.2014.1794


November 06, 2014

4:45 PM | Foods to Improve Your Mood
Scientists are beginning to recognize the link between diet, levels of inflammation in the body, and mood. It is a commonly held belief that your gut is in fact your “second brain.” In fact, more serotonin (the “feel-good” neurotransmitter) is produced in the gut than in the brain. Eating anti-inflammatory nutrients on a regular basis […]

October 28, 2014

7:42 AM | Zinc and depression
"Low dietary zinc intake is associated with a greater incidence of depression in both men and women, as shown in two prospective cohorts".At the risk of overdoing the whole 'you are what you eat' sentiment, today I'm addressing a portion of the peer-reviewed research literature linking issues with zinc availability to depression. That opening quote by the way, comes from the paper by Khanrin Phungamla Vashum and colleagues [1] who looked at self-reported dietary intake of zinc based on […]

Vashum KP, McEvoy M, Milton AH, McElduff P, Hure A, Byles J & Attia J (2014). Dietary zinc is associated with a lower incidence of depression: findings from two Australian cohorts., Journal of affective disorders, 166 249-57. PMID:

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