September 04, 2014

8:51 AM | Epigenetic processes and autism: focusing on immune function?
Although the title of this post talks about the science of epigenetics in autism, I'm actually going to be talking about two papers today, one of which also covers exposure to prenatal immune activation and what effect that might have on epigenetic processes in the mouse brain. This may also be relevant to at least some autism..."Beneath this mask there is an idea, Mr. Creedy. And ideas are bulletproof"First off we have the paper from Nardone and colleagues [1] (open-access) which, following […]

Nardone, S., Sharan Sams, D., Reuveni, E., Getselter, D., Oron, O., Karpuj, M. & Elliott, E. (2014). DNA methylation analysis of the autistic brain reveals multiple dysregulated biological pathways, Translational Psychiatry, 4 (9) DOI: 10.1038/tp.2014.70

Basil, P., Li, Q., Dempster, E., Mill, J., Sham, P., Wong, C. & McAlonan, G. (2014). Prenatal maternal immune activation causes epigenetic differences in adolescent mouse brain, Translational Psychiatry, 4 (9) DOI: 10.1038/tp.2014.80

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