Posts

November 25, 2014

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4:40 PM | A New Function for Gut Bacteria
The microbiome has become an extensively researched topic recently. What new functions do these bacteria have?...

November 12, 2014

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9:53 AM | An inflammatory autism subtype?
The paper from Harumi Jyonouchi and colleagues [1] (open-access) continues a theme from this author with their suggestion of "an imbalance in the production of inflammatory (IL-1ß and IL-6) and counterregulatory (IL-10) cytokines by ‘flare’ ASD-IS [autism spectrum disorder - inflammatory subtype] monocytes".Panic on the streets of Birmingham...'Flare' ASD-IS in this case refers to a coding given to a small participant group (n=24) who were: "defined as those […]

November 06, 2014

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9:30 AM | Neurotensin, autism and tail-chasing Bull Terrriers?
I'm not kidding.The paper by Tsilioni and colleagues [1] (open-access) did indeed look at serum levels of neurotensin and corticotropin-releasing hormone (CRH) in a cohort of children diagnosed with an autism spectrum disorder (ASD) alongside levels in tail-chasing Bull Terrier dogs as compared to unaffected [non tail-chasing] Bull Terriers (BTs) and Labrador Retriever dogs. You may well smirk or even laugh at such research but, as per the recent [preliminary] broccoli chemical - […]

Tsilioni I, Dodman N, Petra AI, Taliou A, Francis K, Moon-Fanelli A, Shuster L & Theoharides TC (2014). Elevated serum neurotensin and CRH levels in children with autistic spectrum disorders and tail-chasing Bull Terriers with a phenotype similar to autism., Translational psychiatry, 4 PMID: http://www.ncbi.nlm.nih.gov/pubmed/25313509

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November 05, 2014

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4:06 PM | Growing Human Stomachs In The Lab
Scientists from the Cincinnati Children’s Hospital Medical Centre have successfully grown miniature stomachs from stem cells. What does this spell for the future of regenerative medicine?...

October 30, 2014

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8:44 AM | Pain and adolescent Chronic Fatigue Syndrome
"We found a higher prevalence of severe pain among adolescents with CFS [Chronic Fatigue Syndrome] and lowered pain thresholds compared with HCs [healthy controls]".That was the headline generated by the study from Anette Winger and colleagues [1] (open-access) looking to describe several parameters tied into experience of pain in the context of CFS. Further: "The total sum of bodily symptoms represented a heavy burden with great functional consequences".Your hokey pokey […]

Winger, A., Kvarstein, G., Wyller, V., Sulheim, D., Fagermoen, E., Smastuen, M. & Helseth, S. (2014). Pain and pressure pain thresholds in adolescents with chronic fatigue syndrome and healthy controls: a cross-sectional study, BMJ Open, 4 (10) DOI: 10.1136/bmjopen-2014-005920

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