Posts

November 18, 2014

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6:15 PM | From H. pylori to Spanish colonialism: the scales of cancer.
Yesterday was the first day of the 4th Integrated Mathematical Oncology Workshop here at Moffitt. This year, it is run jointly with the Center for Infection Research in Cancer and is thus focused on the interaction of infection disease and cancer. This is a topic that I have not focused much attention on — except […]

Kodaman, N., Pazos, A., Schneider, B.G., Piazuelo, M.B., Mera, R., Sobota, R.S., Sicinschi, L.A., Shaffer, C.L., Romero-Gallo, J., de Sablet, T. & Harder, R.H. (2014). Human and Helicobacter pylori coevolution shapes the risk of gastric disease., Proceedings of the National Academy of Sciences of the United States of America, 111 (4) 1455-60. PMID: http://www.ncbi.nlm.nih.gov/pubmed/24474772

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November 17, 2014

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8:00 PM | Why Are All the Sea Stars Dying?
For the last year and a half, sea stars all along North America's Pacific coast - from Baja California all the way to Alaska - have been withering away into nothingness. Today, researchers announced they've found the culprit: it's a virus.Read more...
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7:00 PM | Red meat and cancer: the biological evidence
  Two weeks ago, we discussed the link between red meat consumption and breast cancer risk. This relationship is particularly interesting, given that younger women and those taking birth control pills were at the highest risk for breast cancer, indicating … Continue reading »The post Red meat and cancer: the biological evidence appeared first on Public Health.
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7:00 PM | Red meat and cancer: the biological evidence
  Two weeks ago, we discussed the link between red meat consumption and breast cancer risk. This relationship is particularly interesting, given that younger women and those taking birth control pills were at the highest risk for breast cancer, indicating … Continue reading »The post Red meat and cancer: the biological evidence appeared first on Public Health.

November 13, 2014

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10:25 PM | Patient Zero - Updated
The greatest mysteries have a shadowy figure at the center, Patient Zero. We hunt for Patient Zeroes from all over the map.      

November 07, 2014

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4:50 PM | Eating Disorders: Weekend Reading Links
I am focusing on recent research in eating disorders this month on Brain Posts.Here are some of the research abstracts I will be reviewing for upcoming posts.Clicking on the title will take you to the PubMed abstract and also to a link for the free full-text manuscript.Higher parental education as a risk factor for eating disordersThis study of the Swedish population examined the effect education and social class on risk for eating disorders. Individuals diagnosed with an eating disorder were […]

November 06, 2014

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6:42 PM | Ebola Virus Disease: The Facts Are Important
Patrick J. Brennan, MD, is the Chief Medical Officer of the University of Pennsylvania Health System. He is an infectious disease physician and a former director of tuberculosis control for the Philadelphia Department of Public Health. In this guest post, he writes to share important information about the Ebola virus...

November 05, 2014

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9:56 PM | Why does eating red meat elevate breast cancer risk, especially for young women on the pill?
  The answer to that question is unknown, although it may have its origins in the seedy underbelly of the American food system. Let us unravel how red meat consumption may be associated with breast cancer risk. The U.S. Nurses’ … Continue reading »The post Why does eating red meat elevate breast cancer risk, especially for young women on the pill? appeared first on Public Health.
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9:56 PM | Why does eating red meat elevate breast cancer risk, especially for young women on the pill?
  The answer to that question is unknown, although it may have its origins in the seedy underbelly of the American food system. Let us unravel how red meat consumption may be associated with breast cancer risk. The U.S. Nurses’ … Continue reading »The post Why does eating red meat elevate breast cancer risk, especially for young women on the pill? appeared first on Public Health.

November 03, 2014

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11:16 AM | Autism, epidemiology, and the public perception of evidence
“One day it's C-sections, the next it's pollution, now so many genes. Connect the dots, causation changes like the wind” That quote is from a brief conversation I had on Twitter recently, with someone who is sceptical of the evidence that the causes of autism are overwhelmingly genetic (as described here). For me, it sums up a huge problem in how science is reported and perceived by the general public. This problem is especially stark when it comes to reportage of epidemiology […]
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11:16 AM | Autism, epidemiology, and the public perception of evidence
“One day it's C-sections, the next it's pollution, now so many genes. Connect the dots, causation changes like the wind” That quote is from a brief conversation I had on Twitter recently, with someone who is sceptical of the evidence that the causes of autism are overwhelmingly genetic (as described here). For me, it sums up a huge problem in how science is reported and perceived by the general public. This problem is especially stark when it comes to reportage of epidemiology […]
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8:00 AM | TMI? Personalized probability
I went to my dentist on Friday expecting to go home with a permanent crown on one of my molars but I went home with an appointment with an endodontist for evaluation for a root canal instead.  My dentist, who I think is a very good one, said that 6% of people getting crowns go on to need a root canal, and, based on my symptoms, he was 90% sure I'd be one of those 6%.  Lovely.But what does that 6% even mean?  Just off the top of my head, it could reflect the fallibility of […]

October 30, 2014

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12:00 PM | Public health agencies should prioritize public health based on evidence, not fear
The Editorial: The complexity of health requires an expansion of the areas covered by public health agencies Ed note: This post comes to us from our PLOS Blogs friend Dr Travis Saunders. Travis Saunders has a PhD in Human Kinetics … Continue reading »The post Public health agencies should prioritize public health based on evidence, not fear appeared first on Public Health.
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9:30 AM | Behind the picture: Major Greenwood and the measure of medicine
The introduction of measurement into medicine established the foundations of the modern discipline of biostatistics, crucial to all aspects of medicine, epidemiology and public health. But how did statistics become […]

October 29, 2014

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5:10 PM | This Month in Blastocystis Research (OCT 2014) - Trick or Treat Edition
Over the past 30 days I've hardly had any time to focus on Blastocystis. I've been busy preparing for and attending UEGWeek 2014, preparing abstracts for next year's ECCMID conference in Copenhagen, and I've also put a lot of effort into preparing proposals for this round of grant calls from the Danish Council for Independent Research.  Among other things, we are applying for money to develop DNA-probe based diagnostics, including a unique software, for use in the clinical microbiology lab […]

Fletcher S, Caprarelli G, Merif J, Andresen D, Hal SV, Stark D & Ellis J (2014). Epidemiology and geographical distribution of enteric protozoan infections in sydney, australia., Journal of public health research, 3 (2) 298. PMID: http://www.ncbi.nlm.nih.gov/pubmed/25343139

Nagel R, Bielefeldt-Ohmann H & Traub R (2014). Clinical pilot study: efficacy of triple antibiotic therapy in Blastocystis positive irritable bowel syndrome patients., Gut pathogens, 6 34. PMID: http://www.ncbi.nlm.nih.gov/pubmed/25349629

Nowack EC & Melkonian M (2010). Endosymbiotic associations within protists., Philosophical transactions of the Royal Society of London. Series B, Biological sciences, 365 (1541) 699-712. PMID: http://www.ncbi.nlm.nih.gov/pubmed/20124339

Prodeus TV, Zelia OP, Khlebnikova TA & Pikul' DA (2014). [Extraenteric infection caused by Blastocystis spp. in a female patient with liver abscess]., Meditsinskaia parazitologiia i parazitarnye bolezni, (2) 6-9. PMID: http://www.ncbi.nlm.nih.gov/pubmed/25296418

Citation
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5:10 PM | This Month in Blastocystis Research (OCT 2014) - Trick or Treat Edition
Over the past 30 days I've hardly had any time to focus on Blastocystis. I've been busy preparing for and attending UEGWeek 2014, preparing abstracts for next year's ECCMID conference in Copenhagen, and I've also put a lot of effort into preparing proposals for this round of grant calls from the Danish Council for Independent Research.  Among other things, we are applying for money to develop DNA-probe based diagnostics, including a unique software, for use in the clinical microbiology lab […]

Fletcher S, Caprarelli G, Merif J, Andresen D, Hal SV, Stark D & Ellis J (2014). Epidemiology and geographical distribution of enteric protozoan infections in sydney, australia., Journal of public health research, 3 (2) 298. PMID: http://www.ncbi.nlm.nih.gov/pubmed/25343139

Nagel R, Bielefeldt-Ohmann H & Traub R (2014). Clinical pilot study: efficacy of triple antibiotic therapy in Blastocystis positive irritable bowel syndrome patients., Gut pathogens, 6 34. PMID: http://www.ncbi.nlm.nih.gov/pubmed/25349629

Nowack EC & Melkonian M (2010). Endosymbiotic associations within protists., Philosophical transactions of the Royal Society of London. Series B, Biological sciences, 365 (1541) 699-712. PMID: http://www.ncbi.nlm.nih.gov/pubmed/20124339

Prodeus TV, Zelia OP, Khlebnikova TA & Pikul' DA (2014). [Extraenteric infection caused by Blastocystis spp. in a female patient with liver abscess]., Meditsinskaia parazitologiia i parazitarnye bolezni, (2) 6-9. PMID: http://www.ncbi.nlm.nih.gov/pubmed/25296418

Citation
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5:10 PM | This Month in Blastocystis Research (OCT 2014) - Trick or Treat Edition
Over the past 30 days I've hardly had any time to focus on Blastocystis. I've been busy preparing for and attending UEGWeek 2014, preparing abstracts for next year's ECCMID conference in Copenhagen, and I've also put a lot of effort into preparing proposals for this round of grant calls from the Danish Council for Independent Research.  Among other things, we are applying for money to develop DNA-probe based diagnostics, including a unique software, for use in the clinical microbiology lab […]

Fletcher S, Caprarelli G, Merif J, Andresen D, Hal SV, Stark D & Ellis J (2014). Epidemiology and geographical distribution of enteric protozoan infections in sydney, australia., Journal of public health research, 3 (2) 298. PMID: http://www.ncbi.nlm.nih.gov/pubmed/25343139

Nagel R, Bielefeldt-Ohmann H & Traub R (2014). Clinical pilot study: efficacy of triple antibiotic therapy in Blastocystis positive irritable bowel syndrome patients., Gut pathogens, 6 34. PMID: http://www.ncbi.nlm.nih.gov/pubmed/25349629

Nowack EC & Melkonian M (2010). Endosymbiotic associations within protists., Philosophical transactions of the Royal Society of London. Series B, Biological sciences, 365 (1541) 699-712. PMID: http://www.ncbi.nlm.nih.gov/pubmed/20124339

Prodeus TV, Zelia OP, Khlebnikova TA & Pikul' DA (2014). [Extraenteric infection caused by Blastocystis spp. in a female patient with liver abscess]., Meditsinskaia parazitologiia i parazitarnye bolezni, (2) 6-9. PMID: http://www.ncbi.nlm.nih.gov/pubmed/25296418

Citation
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5:10 PM | This Month in Blastocystis Research (OCT 2014) - Trick or Treat Edition
Over the past 30 days I've hardly had any time to focus on Blastocystis. I've been busy preparing for and attending UEGWeek 2014, preparing abstracts for next year's ECCMID conference in Copenhagen, and I've also put a lot of effort into preparing proposals for this round of grant calls from the Danish Council for Independent Research.  Among other things, we are applying for money to develop DNA-probe based diagnostics, including a unique software, for use in the clinical microbiology lab […]

Fletcher S, Caprarelli G, Merif J, Andresen D, Hal SV, Stark D & Ellis J (2014). Epidemiology and geographical distribution of enteric protozoan infections in sydney, australia., Journal of public health research, 3 (2) 298. PMID: http://www.ncbi.nlm.nih.gov/pubmed/25343139

Nagel R, Bielefeldt-Ohmann H & Traub R (2014). Clinical pilot study: efficacy of triple antibiotic therapy in Blastocystis positive irritable bowel syndrome patients., Gut pathogens, 6 34. PMID: http://www.ncbi.nlm.nih.gov/pubmed/25349629

Nowack EC & Melkonian M (2010). Endosymbiotic associations within protists., Philosophical transactions of the Royal Society of London. Series B, Biological sciences, 365 (1541) 699-712. PMID: http://www.ncbi.nlm.nih.gov/pubmed/20124339

Prodeus TV, Zelia OP, Khlebnikova TA & Pikul' DA (2014). [Extraenteric infection caused by Blastocystis spp. in a female patient with liver abscess]., Meditsinskaia parazitologiia i parazitarnye bolezni, (2) 6-9. PMID: http://www.ncbi.nlm.nih.gov/pubmed/25296418

Citation

October 28, 2014

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3:50 PM | Night Owls Show Increased Alcohol Use Risk
Humans commonly display a circadian rhythm preference for getting up early in the morning or staying up late at night (night owls).This sleep timing, or diurnal preference appears to have genetic contributions.Additionally, diurnal preference may contribute to risk for alcohol consumption as more alcohol is consumed later in the day and during the night time.Nathaniel Watson and colleagues at the University of Washington and the University of Texas recently explored the relationship between […]

October 27, 2014

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9:58 PM | The zombie anti-vaccine lie–Peter Doshi and the appeal to authority
A few  months ago, I wrote an article about Peter Doshi, a Ph.D. who is doing some postdoctoral work at Johns Hopkins University, one of the leading institutions of higher learning in the USA. Doshi is truly not very notable in science, except last year, he wrote an article about flu vaccines, basically employing the Nirvana Fallacy […]Continue reading «The zombie anti-vaccine lie–Peter Doshi and the appeal to authority»

October 26, 2014

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3:54 AM | The MIDAS touch: NIGMS Propels Infectious Disease Research To Golden Age via Computational Modeling
The National Institute of General Medical Sciences (NIGMS), a part of the US National Institutes of Health (NIH), was established in 1962 via an Act of Congress for the "conduct and support of research and research training in the general or basic medical sciences and related natural or behavioral sciences", especially in areas which are interdisciplinary for other institutes under the Act, or alternatively, which fall under no institute’s purview. In these 52 years, the NIGMS has […]
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3:54 AM | The MIDAS touch: NIGMS Propels Infectious Disease Research To Golden Age via Computational Modeling
The National Institute of General Medical Sciences (NIGMS), a part of the US National Institutes of Health (NIH), was established in 1962 via an Act of Congress for the "conduct and support of research and research training in the general or basic medical sciences and related natural or behavioral sciences", especially in areas which are interdisciplinary for other institutes under the Act, or alternatively, which fall under no institute’s purview. In these 52 years, the NIGMS has […]
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3:54 AM | The MIDAS touch: NIGMS Propels Infectious Disease Research To Golden Age via Computational Modeling
The National Institute of General Medical Sciences (NIGMS), a part of the US National Institutes of Health (NIH), was established in 1962 via an Act of Congress for the "conduct and support of research and research training in the general or basic medical sciences and related natural or behavioral sciences", especially in areas which are interdisciplinary for other institutes under the Act, or alternatively, which fall under no institute’s purview. In these 52 years, the NIGMS has […]

October 24, 2014

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7:00 PM | No, Ebola Won't Decide The Outcome Of The Elections
Ebola is at the top of the headlines. The elections are eleven days away. Therefore, the Law of Punditry dictates that political commentators must link these two stories together, forecasting that fears of the deadly virus will determine who controls Congress. Here's why they're completely wrong.Read more...

October 23, 2014

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9:42 PM | The Ebola Outbreak: Hopeful News from the Front Lines
The coverage of the Ebola outbreak in West Africa by U.S. media has often seemed unremittingly grim. So it was with some trepidation that I boarded a plane for Sierra Leone. I was part of a field... -- Read more on ScientificAmerican.com

October 22, 2014

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6:00 PM | How The Hot Zone Created the Worst Myths About Ebola
As an infectious disease epidemiologist and a science communicator in the midst of the biggest Ebola outbreak in history, The Hot Zone is one of the banes of my existence. Read more...
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