October 16, 2014

8:59 AM | MicroRNAs and Chronic Fatigue Syndrome
"No one User wrote me! I'm worth millions of their man-years!"Not so long ago I posted an entry talking about microRNAs and autism (see here). As well as including some rather interesting, if preliminary findings, that particular piece of work also served to introduce yet another layer of complexity to our genome and its expression: microRNAs.I was therefore always going to be more than a little intrigued by the results published by Ekua Brenu and colleagues [1] and their observations on […]

Brenu EW, Ashton KJ, Batovska J, Staines DR & Marshall-Gradisnik SM (2014). High-Throughput Sequencing of Plasma MicroRNA in Chronic Fatigue Syndrome/Myalgic Encephalomyelitis., PloS one, 9 (9) PMID:


October 09, 2014

8:41 AM | Physical activity and fitness levels and autism
Although at present having to be slightly more cautious following some recent surgery (general anaesthetic is awesome by the way!), I normally consider myself to be quite an active person. Through previous discussions on this blog covering topics on the positive effects of walking (see here) and the physical+ benefits of the martial arts (see here) I'd like to think that there are quite a few ways and means that the population at large can easily increase their daily physical activity levels. […]

Tyler, K., MacDonald, M. & Menear, K. (2014). Physical Activity and Physical Fitness of School-Aged Children and Youth with Autism Spectrum Disorders, Autism Research and Treatment, 2014 1-6. DOI: 10.1155/2014/312163


October 06, 2014

8:36 AM | Correcting vitamin D levels improves fatigue severity?
I was interested to read the paper by Satyajeet Roy and colleagues [1] (open-access here) concluding that: "Normalization of vitamin D levels with ergocalciferol therapy significantly improves the severity of... fatigue symptoms". Ergocalciferol by the way, means vitamin D2, which is distinct from cholecalciferol (vitamin D3), the seemingly more desirable form of vitamin D supplementation (see here)."It's beyond my control"The Roy paper is open-access but a few details might be […]

Roy S, Sherman A, Monari-Sparks MJ, Schweiker O & Hunter K (2014). Correction of Low Vitamin D Improves Fatigue: Effect of Correction of Low Vitamin D in Fatigue Study (EViDiF Study)., North American journal of medical sciences, 6 (8) 396-402. PMID:

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