Posts

September 30, 2014

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9:06 AM | Autoimmune thyroiditis and depressive disorder
"Our study demonstrates a strong association between anti-TPO levels, which are considered to be of diagnostic value for autoimmune thyroiditis... with uni- or bipolar depression.""Beware the bad cat bearing a grudge"So said the study published by Detlef Degner and colleagues [1]. Anti-TPO antibodies by the way, refers to anti-thyroid peroxidase antibodies which, as the name suggests, are antibodies against thyroid peroxidase, an important step in the production of thyroid […]

Degner D, Haust M, Meller J, Rüther E & Reulbach U (2014). Association between autoimmune thyroiditis and depressive disorder in psychiatric outpatients., European archives of psychiatry and clinical neuroscience, PMID: http://www.ncbi.nlm.nih.gov/pubmed/25193677

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September 25, 2014

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2:37 PM | A New Discovery in the Treatment of Autoimmunity and Chronic Inflammation
Lupus, Type 1 diabetes, and multiple sclerosis are all diseases brought on by autoimmunity — the bodies inability to tell itself apart from foreign invaders. Finding a cure, or even a suitable […]

Dubiella C, Cui H, Gersch M, Brouwer AJ, Sieber SA, Krüger A, Liskamp RM & Groll M (2014). Selective Inhibition of the Immunoproteasome by Ligand-Induced Crosslinking of the Active Site., Angewandte Chemie (International ed. in English), PMID: http://www.ncbi.nlm.nih.gov/pubmed/25244435

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September 19, 2014

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11:28 PM | Nanosponges Clean up Antibody-mediated Autoimmune Disease
What does lupus, rheumatoid arthritis, type I diabetes, multiple sclerosis, and rheumatic heart disease have in common? All of these (and many other) apparently unrelated disorders are caused by autoimmunity, […]

Copp JA, Fang RH, Luk BT, Hu CM, Gao W, Zhang K & Zhang L (2014). Clearance of pathological antibodies using biomimetic nanoparticles., Proceedings of the National Academy of Sciences of the United States of America, 111 (37) 13481-6. PMID: http://www.ncbi.nlm.nih.gov/pubmed/25197051

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September 17, 2014

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10:29 AM | Autoimmune disease risk and eating disorders
"We were set up. The cops were waiting for us.""We observed an association between eating disorders and several autoimmune diseases with different genetic backgrounds. Our findings support the link between immune-mediated mechanisms and development of eating disorders".So said the paper by Anu Raevuori and colleagues [1] (open-access) based on an analysis of over 2300 people "treated at the Eating Disorder Unit of Helsinki University Central Hospital between 1995 and 2010" compared with […]

September 03, 2014

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6:35 PM | Are Viruses Causing Celiac Disease?
Celiac disease is triggered by the body's autoimmune response to the protein gluten, but do viruses contribute to this reaction too? UChicago Celiac Disease Center research Dr. Valentina Discepolo writes about how understanding the body's response could lead to better treatment.
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