Posts

July 28, 2014

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6:53 PM | Watch ALL the neurons in a brain: Ahrens and Freeman continue their reign of terror
Okay, not quite all of them. But it looks like Misha Ahrens and Jeremy Freeman are going to continue their reign of terror, imaging the whole zebrafish brain as if it’s no big deal. Yeah they’ve got almost every neuron of a vertebrate, so what? Besides figuring out that not shooting light at the eyes might […]

Freeman, J., Vladimirov, N., Kawashima, T., Mu, Y., Sofroniew, N., Bennett, D., Rosen, J., Yang, C., Looger, L. & Ahrens, M. & (2014). Mapping brain activity at scale with cluster computing, Nature Methods, DOI: 10.1038/nmeth.3041

Vladimirov, N., Mu, Y., Kawashima, T., Bennett, D., Yang, C., Looger, L., Keller, P., Freeman, J. & Ahrens, M. (2014). Light-sheet functional imaging in fictively behaving zebrafish, Nature Methods, DOI: 10.1038/nmeth.3040

Citation
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6:53 PM | Watch ALL the neurons in a brain: Ahrens and Freeman continue their reign of terror
Okay, not quite all of them. But it looks like Misha Ahrens and Jeremy Freeman are going to continue their reign of terror, imaging the whole zebrafish brain as if it’s no big deal. Yeah they’ve got almost every neuron of a vertebrate, so what? Besides figuring out that not shooting light at the eyes might […]

Freeman, J., Vladimirov, N., Kawashima, T., Mu, Y., Sofroniew, N., Bennett, D., Rosen, J., Yang, C., Looger, L. & Ahrens, M. & (2014). Mapping brain activity at scale with cluster computing, Nature Methods, DOI: 10.1038/nmeth.3041

Vladimirov, N., Mu, Y., Kawashima, T., Bennett, D., Yang, C., Looger, L., Keller, P., Freeman, J. & Ahrens, M. (2014). Light-sheet functional imaging in fictively behaving zebrafish, Nature Methods, DOI: 10.1038/nmeth.3040

Citation

July 27, 2014

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11:52 PM | This Man Is Able to Reproduce Meticulously Accurate Cityscapes After A Single Fly-Over (Video)
They call him the human camera. Stephen Wiltshire was born in London in 1974. As a child, Stephen was a mute. At the age of three he was diagnosed as autistic, and in that same year his father died in a motorcycle accident. At five he was sent to the Queensmill School for the autistic […]
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4:54 PM | Pavlov Would Be Proud: Teach The Brain To Feel Less Pain
People can be conditioned to feel less pain when they hear a neutral sound, new research from the University of Luxembourg has found. This lends weight to the idea that we can learn to use mind-over-matter to beat pain. Scientists have known for many years that on-going pain in one part of the body is reduced when a new pain is inflicted to another part of the body. This pain blocking is a physiological reaction by the nervous system to help the body deal with a potentially more relevant […]
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4:00 AM | Neuroscience and Creativity
Edited by Oshin Vartanian, Adam S Bristol and James C Kaufman Synopsis: This volume offers a comprehensive overview of the latest neuroscientific approaches to the scientific study of creativity. In chapters that progress logically from neurobiological […]

July 26, 2014

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8:02 PM | Morsels For The Mind – 25/07/2014
Every day we provide you with Six Incredible Things Before Breakfast to nibble away at. Here you can fill your brain with the most intellectually stimulating “amuse bouches” from the past week – a veritable smorgasbord for the cranium. They’re all here for you to load up your plate – this week’s “Morsels for the mind”. Enjoy! If you do nothing else, make sure to check out the “Reads / views / listens of the week”. **** Star Wars […]
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8:02 PM | Morsels For The Mind – 25/07/2014
Every day we provide you with Six Incredible Things Before Breakfast to nibble away at. Here you can fill your brain with the most intellectually stimulating “amuse bouches” from the past week – a veritable smorgasbord for the cranium. They’re all here for you to load up your plate – this week’s “Morsels for the mind”. Enjoy! If you do nothing else, make sure to check out the “Reads / views / listens of the week”. **** Star Wars […]
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6:34 PM | Why Calling People Dumb Just Proves Your Own Ignorance
I’m no saint. Just like everyone else, I get frustrated with people from time to time. If you catch me after a particularly maddening encounter, you may hear the words “ignorant”, “bigoted”, “close-minded”, and maybe even “asshole”. But one word you will never hear me use to describe a person is “dumb”. The increasingly popular idea that the […]
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5:18 PM | Save the Neurons: Fighting the Effects of Parkinsons
Possibly one of the most famous cases of parkinson’s is Michael J. Fox. More than just the “shakes” parkinson’s can cause a whole host of other problems mentally and physically […]

Barnum CJ, Chen X, Chung J, Chang J, Williams M, Grigoryan N, Tesi RJ & Tansey MG (2014). Peripheral Administration of the Selective Inhibitor of Soluble Tumor Necrosis Factor (TNF) XPro1595 Attenuates Nigral Cell Loss and Glial Activation in 6-OHDA Hemiparkinsonian Rats., Journal of Parkinson's disease, PMID: http://www.ncbi.nlm.nih.gov/pubmed/25061061

Citation
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5:18 PM | Save the Neurons: Fighting the Effects of Parkinsons
Possibly one of the most famous cases of parkinson’s is Michael J. Fox. More than just the “shakes” parkinson’s can cause a whole host of other problems mentally and physically […]

Barnum CJ, Chen X, Chung J, Chang J, Williams M, Grigoryan N, Tesi RJ & Tansey MG (2014). Peripheral Administration of the Selective Inhibitor of Soluble Tumor Necrosis Factor (TNF) XPro1595 Attenuates Nigral Cell Loss and Glial Activation in 6-OHDA Hemiparkinsonian Rats., Journal of Parkinson's disease, PMID: http://www.ncbi.nlm.nih.gov/pubmed/25061061

Citation
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5:18 PM | Save the Neurons: Fighting the Effects of Parkinsons
Possibly one of the most famous cases of parkinson’s is Michael J. Fox. More than just the “shakes” parkinson’s can cause a whole host of other problems mentally and physically […]

Barnum CJ, Chen X, Chung J, Chang J, Williams M, Grigoryan N, Tesi RJ & Tansey MG (2014). Peripheral Administration of the Selective Inhibitor of Soluble Tumor Necrosis Factor (TNF) XPro1595 Attenuates Nigral Cell Loss and Glial Activation in 6-OHDA Hemiparkinsonian Rats., Journal of Parkinson's disease, PMID: http://www.ncbi.nlm.nih.gov/pubmed/25061061

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11:15 AM | Robo rehab | Mo Costandi
Robot-assisted rehabilitation is gaining traction in hospital stroke units, but exoskeleton-type devices may actually discourage patients from performing their exercises.Hundreds of millions of people tuned in to the World Cup Opening Ceremony in São Paulo last month, to watch artists such as Jennifer Lopez and Shakira perform before the first match kicked off. But the real highlight - which was apparently ignored by most of the media outlets covering the event - was a one-minute […]

July 25, 2014

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5:47 PM | Fighting the Obesity Epidemic with X-box [No, not that one]
Despite all the efforts, people are losing the war on obesity. There is probably a number of factors involved, genetics, underlying medical problems, most of all diet, but in any […]

Williams KW, Liu T, Kong X, Fukuda M, Deng Y, Berglund ED, Deng Z, Gao Y, Liu T, Sohn JW & Jia L (2014). Xbp1s in Pomc Neurons Connects ER Stress with Energy Balance and Glucose Homeostasis., Cell metabolism, PMID: http://www.ncbi.nlm.nih.gov/pubmed/25017942

Citation
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5:47 PM | Fighting the Obesity Epidemic with X-box [No, not that one]
Despite all the efforts, people are losing the war on obesity. There is probably a number of factors involved, genetics, underlying medical problems, most of all diet, but in any […]

Williams KW, Liu T, Kong X, Fukuda M, Deng Y, Berglund ED, Deng Z, Gao Y, Liu T, Sohn JW & Jia L (2014). Xbp1s in Pomc Neurons Connects ER Stress with Energy Balance and Glucose Homeostasis., Cell metabolism, PMID: http://www.ncbi.nlm.nih.gov/pubmed/25017942

Citation
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5:47 PM | Fighting the Obesity Epidemic with X-box [No, not that one]
Despite all the efforts, people are losing the war on obesity. There is probably a number of factors involved, genetics, underlying medical problems, most of all diet, but in any […]

Williams KW, Liu T, Kong X, Fukuda M, Deng Y, Berglund ED, Deng Z, Gao Y, Liu T, Sohn JW & Jia L (2014). Xbp1s in Pomc Neurons Connects ER Stress with Energy Balance and Glucose Homeostasis., Cell metabolism, PMID: http://www.ncbi.nlm.nih.gov/pubmed/25017942

Citation
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5:47 PM | Fighting the Obesity Epidemic with X-box [No, not that one]
Despite all the efforts, people are losing the war on obesity. There is probably a number of factors involved, genetics, underlying medical problems, most of all diet, but in any […]

Williams KW, Liu T, Kong X, Fukuda M, Deng Y, Berglund ED, Deng Z, Gao Y, Liu T, Sohn JW & Jia L (2014). Xbp1s in Pomc Neurons Connects ER Stress with Energy Balance and Glucose Homeostasis., Cell metabolism, PMID: http://www.ncbi.nlm.nih.gov/pubmed/25017942

Citation
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2:36 PM | Pheromones And Urine: Why It Takes Two To Court
Researchers have identified the functions of two classes of pheromone receptors, and found pheromones crucial to triggering the mating process in mice.read more
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2:28 PM | The Human Brain Project kerfuffle
We’ve had a lot of controversy recently about the Human Brain Project, a European initiative that plans to spend a billion-plus Euros over the next few years to advance brain research.  To summarize ultra-briefly, a group of several hundred European neuroscientists have signed an open letter arguing that the Project is going in the wrong … Continue reading »
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2:01 PM | Neurosciences: Bringing the TReND to Africa
The Lindau-alumni founded NGO TReND in Africa is dedicated to improve research conditions on the continent. Whilst studying for her PhD in neurosciences at Cambridge University, Lindau alumna, Lucia Prieto-Godino (2014, physiology/medicine), met Sadiq Yusuf and was shocked to discover “that many East African neuroscientists were still using expensive rat models for their research despite […]
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5:00 AM | Matrix Metalloproteinase 9 Enzyme Linked To Autistic Behavior
Fragile X syndrome (FXS) is a genetic disorder that causes obsessive-compulsive and repetitive behaviors, and other behaviors on the autistic spectrum, as well as cognitive deficits. It is the most common inherited cause of mental impairment and linked to autism. Researchers have published a study that sheds light on the cause of autistic behaviors in FXS. The study describes how MMP-9, an enzyme, plays a critical role in the development of autistic behaviors and synapse irregularities, with […]
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12:47 AM | Know your brain: Meninges
Where are they? Close-up view of the meninges surrounding the brain. The term meninges comes from the Greek for "membrane" and refers to the three membranes that surround the brain and spinal cord. The membrane layers (discussed in detail below) from the outside in are the: dura mater, arachnoid mater, and pia mater. Their positioning around the brain can be seen in the image to the right.What are they and what do they do?The brain is soft and mushy, and […]

Patel, N. & Kirmi, O. (2009). Anatomy and Imaging of the Normal Meninges, Seminars in Ultrasound, CT and MRI, 30 (6) 559-564. DOI: 10.1053/j.sult.2009.08.006

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July 24, 2014

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11:24 PM | Salmon and Spinal Cod Regeneration, er… Cord
Fish might not be the first thing you think about when we talk spinal cord injury but that is exactly what scientists are doing. Don’t ask where they got the […]

Lewandowski, G. & Steward, O. (2014). AAVshRNA-Mediated Suppression of PTEN in Adult Rats in Combination with Salmon Fibrin Administration Enables Regenerative Growth of Corticospinal Axons and Enhances Recovery of Voluntary Motor Function after Cervical Spinal Cord Injury, Journal of Neuroscience, 34 (30) 9951-9962. DOI: 10.1523/JNEUROSCI.1996-14.2014

Citation
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11:24 PM | Salmon and Spinal Cod Regeneration, er… Cord
Fish might not be the first thing you think about when we talk spinal cord injury but that is exactly what scientists are doing. Don’t ask where they got the […]

Lewandowski, G. & Steward, O. (2014). AAVshRNA-Mediated Suppression of PTEN in Adult Rats in Combination with Salmon Fibrin Administration Enables Regenerative Growth of Corticospinal Axons and Enhances Recovery of Voluntary Motor Function after Cervical Spinal Cord Injury, Journal of Neuroscience, 34 (30) 9951-9962. DOI: 10.1523/JNEUROSCI.1996-14.2014

Citation
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11:24 PM | Salmon and Spinal Cod Regeneration, er… Cord
Fish might not be the first thing you think about when we talk spinal cord injury but that is exactly what scientists are doing. Don’t ask where they got the […]

Lewandowski, G. & Steward, O. (2014). AAVshRNA-Mediated Suppression of PTEN in Adult Rats in Combination with Salmon Fibrin Administration Enables Regenerative Growth of Corticospinal Axons and Enhances Recovery of Voluntary Motor Function after Cervical Spinal Cord Injury, Journal of Neuroscience, 34 (30) 9951-9962. DOI: 10.1523/JNEUROSCI.1996-14.2014

Citation
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11:24 PM | Salmon and Spinal Cod Regeneration, er… Cord
Fish might not be the first thing you think about when we talk spinal cord injury but that is exactly what scientists are doing. Don’t ask where they got the […]

Lewandowski, G. & Steward, O. (2014). AAVshRNA-Mediated Suppression of PTEN in Adult Rats in Combination with Salmon Fibrin Administration Enables Regenerative Growth of Corticospinal Axons and Enhances Recovery of Voluntary Motor Function after Cervical Spinal Cord Injury, Journal of Neuroscience, 34 (30) 9951-9962. DOI: 10.1523/JNEUROSCI.1996-14.2014

Citation
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11:24 PM | Salmon and Spinal Cod Regeneration, er… Cord
Fish might not be the first thing you think about when we talk spinal cord injury but that is exactly what scientists are doing. Don’t ask where they got the […]

Lewandowski, G. & Steward, O. (2014). AAVshRNA-Mediated Suppression of PTEN in Adult Rats in Combination with Salmon Fibrin Administration Enables Regenerative Growth of Corticospinal Axons and Enhances Recovery of Voluntary Motor Function after Cervical Spinal Cord Injury, Journal of Neuroscience, 34 (30) 9951-9962. DOI: 10.1523/JNEUROSCI.1996-14.2014

Citation
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9:20 PM | An Argument for More Biologically Accurate Emoji
Over at Beatrice the Biologist, cartoonist-cum-science blogger Katie McKissick has thrown down the gauntlet to "I <3 You." Because science. Read more...
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9:11 PM | Lucy’s Brain: Use it or lose it
With the Lucy movie coming out, we’ve been really curious here at NeuWrite about what marvelous new life skills Scarlett Johansson will accrue, now that she can use more than 10% of her brain. As forward-thinking neuroscientists, we’ve been speculating: what would Lucy be able to do with such incredible and unprecedented brain power? The […]
Editor's Pick
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8:58 PM | Why the new paper by Christakis and Fowler on friendship makes me queasy
I am a neuroscientist, and as a neuroscientist I have a strange belief that most of who we are comes from our brains. My entire career is based around understanding behavior from this neural level which I feel to be fairly justifiable. So when I see paper looking at the genetics of behavior, I expect to see at […]

Christakis NA & Fowler JH (2014). Friendship and natural selection., Proceedings of the National Academy of Sciences of the United States of America, 111 (Supplement 3) 10796-10801. PMID: http://www.ncbi.nlm.nih.gov/pubmed/25024208

Ripke, S., Neale, B., Corvin, A., Walters, J., Farh, K., Holmans, P., Lee, P., Bulik-Sullivan, B., Collier, D., Huang, H. & Pers, T. (2014). Biological insights from 108 schizophrenia-associated genetic loci, Nature, 511 (7510) 421-427. DOI: 10.1038/nature13595

Citation
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8:58 PM | Why the new paper by Christakis and Fowler on friendship makes me queasy
I am a neuroscientist, and as a neuroscientist I have a strange belief that most of who we are comes from our brains. My entire career is based around understanding behavior from this neural level which I feel to be fairly justifiable. So when I see paper looking at the genetics of behavior, I expect to see at […]

Christakis NA & Fowler JH (2014). Friendship and natural selection., Proceedings of the National Academy of Sciences of the United States of America, 111 (Supplement 3) 10796-10801. PMID: http://www.ncbi.nlm.nih.gov/pubmed/25024208

Ripke, S., Neale, B., Corvin, A., Walters, J., Farh, K., Holmans, P., Lee, P., Bulik-Sullivan, B., Collier, D., Huang, H. & Pers, T. (2014). Biological insights from 108 schizophrenia-associated genetic loci, Nature, 511 (7510) 421-427. DOI: 10.1038/nature13595

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