Posts

March 26, 2015

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6:20 PM | High-fat diet causes brain inflammation and alters behavior
We hear in the media all the time, obesity is effecting our health. In most cases when we talk obesity we are talking about heart disease, sedentary activity, or chronic overeating. But what if a high-fat diet — regardless of obesity — has more than just an affect on your waistline? What if the consumption of fatty […]

Bruce-Keller, A., Salbaum, J., Luo, M., Blanchard, E., Taylor, C., Welsh, D. & Berthoud, H. (2015). Obese-type Gut Microbiota Induce Neurobehavioral Changes in the Absence of Obesity, Biological Psychiatry, 77 (7) 607-615. DOI: 10.1016/j.biopsych.2014.07.012

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6:20 PM | High-fat diet causes brain inflammation and alters behavior
We hear in the media all the time, obesity is effecting our health. In most cases when we talk obesity we are talking about heart disease, sedentary activity, or chronic overeating. But what if a high-fat diet — regardless of obesity — has more than just an affect on your waistline? What if the consumption of fatty […]

Bruce-Keller, A., Salbaum, J., Luo, M., Blanchard, E., Taylor, C., Welsh, D. & Berthoud, H. (2015). Obese-type Gut Microbiota Induce Neurobehavioral Changes in the Absence of Obesity, Biological Psychiatry, 77 (7) 607-615. DOI: 10.1016/j.biopsych.2014.07.012

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4:30 PM | Liver Bile May Extend Life & Destroy TumorsThis study is...
Liver Bile May Extend Life & Destroy TumorsThis study is still in early phases, so don’t go around drinking any gross bile stuff. (And I won’t even ask how you got that!)Also, pretty cool that this discovery stemmed from anti-aging research. I’m still wondering if I’ll be part of the first generation of humans that can decide when and if to die - or if I’ll be a member of the last generation to not have those options! Highlights:..For the study, the research […]
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12:15 PM | The quack view of preventing cancer versus reality and Angelina Jolie, part 3
I happen to be in Houston right now attending the Society of Surgical Oncology annual meeting. Sadly, I’m only about 12 miles away from the lair of everybody’s favorite faux clinical researcher and purveyor of a cancer cure that isn’t, Stanislaw Burzynski. Such is life. In any case, this conference is all about cancer and…
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11:39 AM | Autism increases risk of nonaffective psychotic disorder and bipolar disorder
Published at the same time and in the same journal as the 'MoBa does bowel issues in autism' paper from Bresnahan and colleagues [1], the study results from Jean-Paul Selten et al [2] reporting that "A diagnosis of ASD [autism spectrum disorder] is associated with a substantially increased risk for NAPD [nonaffective psychotic disorder] and BD [bipolar disorder]" has, at the time of writing this post, received little or no press attention in comparison despite […]

Selten JP, Lundberg M, Rai D & Magnusson C (2015). Risks for Nonaffective Psychotic Disorder and Bipolar Disorder in Young People With Autism Spectrum Disorder: A Population-Based Study., JAMA psychiatry, PMID: http://www.ncbi.nlm.nih.gov/pubmed/25806797

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March 25, 2015

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9:59 PM | Immunotherapy, a promising new treatment of Alzheimer’s disease
Alzheimer’s disease, it slowly takes things away from the person without giving anything back. Right now there is no cure and at best we can slow the progression in some cases. Time is always a factor and no two cases are the same. However, new treatments are in the works and a new study has […]

Castillo-Carranza, D., Guerrero-Munoz, M., Sengupta, U., Hernandez, C., Barrett, A., Dineley, K. & Kayed, R. (2015). Tau Immunotherapy Modulates Both Pathological Tau and Upstream Amyloid Pathology in an Alzheimer's Disease Mouse Model, Journal of Neuroscience, 35 (12) 4857-4868. DOI: 10.1523/JNEUROSCI.4989-14.2015

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9:59 PM | Immunotherapy, a promising new treatment of Alzheimer’s disease
Alzheimer’s disease, it slowly takes things away from the person without giving anything back. Right now there is no cure and at best we can slow the progression in some cases. Time is always a factor and no two cases are the same. However, new treatments are in the works and a new study has […]

Castillo-Carranza, D., Guerrero-Munoz, M., Sengupta, U., Hernandez, C., Barrett, A., Dineley, K. & Kayed, R. (2015). Tau Immunotherapy Modulates Both Pathological Tau and Upstream Amyloid Pathology in an Alzheimer's Disease Mouse Model, Journal of Neuroscience, 35 (12) 4857-4868. DOI: 10.1523/JNEUROSCI.4989-14.2015

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9:59 PM | Immunotherapy, a promising new treatment of Alzheimer’s disease
Alzheimer’s disease, it slowly takes things away from the person without giving anything back. Right now there is no cure and at best we can slow the progression in some cases. Time is always a factor and no two cases are the same. However, new treatments are in the works and a new study has […]

Castillo-Carranza, D., Guerrero-Munoz, M., Sengupta, U., Hernandez, C., Barrett, A., Dineley, K. & Kayed, R. (2015). Tau Immunotherapy Modulates Both Pathological Tau and Upstream Amyloid Pathology in an Alzheimer's Disease Mouse Model, Journal of Neuroscience, 35 (12) 4857-4868. DOI: 10.1523/JNEUROSCI.4989-14.2015

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9:57 PM | MoBa does bowel issues in autism
'MoBa' in the title of this post, refers to the Norwegian Mother and Child Cohort Study and a handy resource which has already impacted on autism research (see here for example).Now MoBa has turned its epidemiological clout to an issue which less and less is encountering scientific resistance: are gastrointestinal (GI) symptoms over-represented when it comes to a diagnosis of autism? Further, when do such bowel issues start to present?The answer, shown in the paper by Michaeline […]

Bresnahan, M., Hornig, M., Schultz, A., Gunnes, N., Hirtz, D., Lie, K., Magnus, P., Reichborn-Kjennerud, T., Roth, C., Schjølberg, S. & Stoltenberg, C. (2015). Association of Maternal Report of Infant and Toddler Gastrointestinal Symptoms With Autism, JAMA Psychiatry, DOI: 10.1001/jamapsychiatry.2014.3034

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5:30 PM | Wondering What To Expect After A Medical Abortion? Read This.
The latest installment of Oh Joy, Sex Toy offers an accessible, informative, and non-judgmental overview of medical abortion, one of several choices available to newly pregnant persons. Read more...
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5:03 PM | Cracking the blood-brain barrier with magnetic nanoparticles
The blood-brain barrier, the thorn in the side of medicine. It makes using drugs directed for the brain ineffective at best and unusable at worst. This barrier runs inside almost all vessels in the brain and protects it from elements circulating in the blood that may be toxic to the brain. This barrier means that […]

Tabatabaei, S., Girouard, H., Carret, A. & Martel, S. (2015). Remote control of the permeability of the blood–brain barrier by magnetic heating of nanoparticles: A proof of concept for brain drug delivery, Journal of Controlled Release, 206 49-57. DOI: 10.1016/j.jconrel.2015.02.027

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5:03 PM | Cracking the blood-brain barrier with magnetic nanoparticles
The blood-brain barrier, the thorn in the side of medicine. It makes using drugs directed for the brain ineffective at best and unusable at worst. This barrier runs inside almost all vessels in the brain and protects it from elements circulating in the blood that may be toxic to the brain. This barrier means that […]

Tabatabaei, S., Girouard, H., Carret, A. & Martel, S. (2015). Remote control of the permeability of the blood–brain barrier by magnetic heating of nanoparticles: A proof of concept for brain drug delivery, Journal of Controlled Release, 206 49-57. DOI: 10.1016/j.jconrel.2015.02.027

Citation
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5:03 PM | Cracking the blood-brain barrier with magnetic nanoparticles
The blood-brain barrier, the thorn in the side of medicine. It makes using drugs directed for the brain ineffective at best and unusable at worst. This barrier runs inside almost all vessels in the brain and protects it from elements circulating in the blood that may be toxic to the brain. This barrier means that […]

Tabatabaei, S., Girouard, H., Carret, A. & Martel, S. (2015). Remote control of the permeability of the blood–brain barrier by magnetic heating of nanoparticles: A proof of concept for brain drug delivery, Journal of Controlled Release, 206 49-57. DOI: 10.1016/j.jconrel.2015.02.027

Citation
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5:03 PM | Cracking the blood-brain barrier with magnetic nanoparticles
The blood-brain barrier, the thorn in the side of medicine. It makes using drugs directed for the brain ineffective at best and unusable at worst. This barrier runs inside almost all vessels in the brain and protects it from elements circulating in the blood that may be toxic to the brain. This barrier means that […]

Tabatabaei, S., Girouard, H., Carret, A. & Martel, S. (2015). Remote control of the permeability of the blood–brain barrier by magnetic heating of nanoparticles: A proof of concept for brain drug delivery, Journal of Controlled Release, 206 49-57. DOI: 10.1016/j.jconrel.2015.02.027

Citation
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5:03 PM | Cracking the blood-brain barrier with magnetic nanoparticles
The blood-brain barrier, the thorn in the side of medicine. It makes using drugs directed for the brain ineffective at best and unusable at worst. This barrier runs inside almost all vessels in the brain and protects it from elements circulating in the blood that may be toxic to the brain. This barrier means that […]

Tabatabaei, S., Girouard, H., Carret, A. & Martel, S. (2015). Remote control of the permeability of the blood–brain barrier by magnetic heating of nanoparticles: A proof of concept for brain drug delivery, Journal of Controlled Release, 206 49-57. DOI: 10.1016/j.jconrel.2015.02.027

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11:00 AM | Medical marijuana and the new herbalism, part 3: Cannabis does not cure breast cancer
It’s been a while since I discussed medical marijuana, even though it’s a topic I’ve been meaning to come back to since I first dubbed medical marijuana to be the equivalent of herbalism and discussed how the potential of cannabinoids to treat cancer has been, thus far, unimpressive, with relatively modest antitumor effects. The reason…
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10:50 AM | Three parent babies: it’s not what you think
Most of us came into this world through a moment of passion between our father and mother. Not so for everyone. In the world today there are 200,000 people who were not conceived in the conventional way – but in a Petri dish. For the past 35 years, IVF (In Vitro Fertilisation) and similar ‘test … Continue reading →
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9:33 AM | Autism and depression: interlinked?
"A possible implication is that interventions aimed at either autism symptoms or symptoms of depression may improve the other."That was the intriguing statement made by Per Normann Andersen and colleagues [1] who "investigated the course of and association among changes in autism symptoms, depression symptoms and executive functions (EF) in children with high-functioning autism (HFA)." Aside from frowning a little at the mention of the concept of 'high-functioning' I assume to denote those […]

Andersen PN, Skogli EW, Hovik KT, Egeland J & Øie M (2015). Associations Among Symptoms of Autism, Symptoms of Depression and Executive Functions in Children with High-Functioning Autism: A 2 Year Follow-Up Study., Journal of autism and developmental disorders, PMID: http://www.ncbi.nlm.nih.gov/pubmed/25763986

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12:00 AM | Science Book a Day Interviews Paul J Zak
Special thanks to Paul J Zak for answering 5 questions about his recently featured book – The Moral Molecule: The Source of Love and Prosperity Paul J. Zak is a scientist, prolific author, and public speaker. His book […]

March 24, 2015

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7:41 PM | Most published medical research is a failure – it’s not what you think
The Skeptical Raptor, stalking pseudoscience in the internet jungle. Yes, you read that right. This so-called shill for the pharmaceutical industry is calling them as I see them–most published medical research articles present information that is eventually a failure. Now by failure I mean that more often than not, claims that are supported by one or two published articles, rarely lead to a marketed product. I … Continue reading Most published medical research is a […]
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5:44 PM | Milk, not just for your bones, for your brain
Milk, depending on who you ask it’s either great or the devil. In the US drinking milk is common; not so much in other parts of the world. This has lead to questions about why we even drink milk and how real its reported health claims actually are. Well new research has found a correlation between […]

Choi, I., Lee, P., Denney, D., Spaeth, K., Nast, O., Ptomey, L., Roth, A., Lierman, J. & Sullivan, D. (2014). Dairy intake is associated with brain glutathione concentration in older adults, American Journal of Clinical Nutrition, 101 (2) 287-293. DOI: 10.3945/ajcn.114.096701

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5:44 PM | Milk, not just for your bones, for your brain
Milk, depending on who you ask it’s either great or the devil. In the US drinking milk is common; not so much in other parts of the world. This has lead to questions about why we even drink milk and how real its reported health claims actually are. Well new research has found a correlation between […]

Choi, I., Lee, P., Denney, D., Spaeth, K., Nast, O., Ptomey, L., Roth, A., Lierman, J. & Sullivan, D. (2014). Dairy intake is associated with brain glutathione concentration in older adults, American Journal of Clinical Nutrition, 101 (2) 287-293. DOI: 10.3945/ajcn.114.096701

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5:44 PM | Milk, not just for your bones, for your brain
Milk, depending on who you ask it’s either great or the devil. In the US drinking milk is common; not so much in other parts of the world. This has lead to questions about why we even drink milk and how real its reported health claims actually are. Well new research has found a correlation between […]

Choi, I., Lee, P., Denney, D., Spaeth, K., Nast, O., Ptomey, L., Roth, A., Lierman, J. & Sullivan, D. (2014). Dairy intake is associated with brain glutathione concentration in older adults, American Journal of Clinical Nutrition, 101 (2) 287-293. DOI: 10.3945/ajcn.114.096701

Citation
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5:44 PM | Milk, not just for your bones, for your brain
Milk, depending on who you ask it’s either great or the devil. In the US drinking milk is common; not so much in other parts of the world. This has lead to questions about why we even drink milk and how real its reported health claims actually are. Well new research has found a correlation between […]

Choi, I., Lee, P., Denney, D., Spaeth, K., Nast, O., Ptomey, L., Roth, A., Lierman, J. & Sullivan, D. (2014). Dairy intake is associated with brain glutathione concentration in older adults, American Journal of Clinical Nutrition, 101 (2) 287-293. DOI: 10.3945/ajcn.114.096701

Citation
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5:44 PM | Milk, not just for your bones, for your brain
Milk, depending on who you ask it’s either great or the devil. In the US drinking milk is common; not so much in other parts of the world. This has lead to questions about why we even drink milk and how real its reported health claims actually are. Well new research has found a correlation between […]

Choi, I., Lee, P., Denney, D., Spaeth, K., Nast, O., Ptomey, L., Roth, A., Lierman, J. & Sullivan, D. (2014). Dairy intake is associated with brain glutathione concentration in older adults, American Journal of Clinical Nutrition, 101 (2) 287-293. DOI: 10.3945/ajcn.114.096701

Citation
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5:44 PM | Milk, not just for your bones, for your brain
Milk, depending on who you ask it’s either great or the devil. In the US drinking milk is common; not so much in other parts of the world. This has lead to questions about why we even drink milk and how real its reported health claims actually are. Well new research has found a correlation between […]

Choi, I., Lee, P., Denney, D., Spaeth, K., Nast, O., Ptomey, L., Roth, A., Lierman, J. & Sullivan, D. (2014). Dairy intake is associated with brain glutathione concentration in older adults, American Journal of Clinical Nutrition, 101 (2) 287-293. DOI: 10.3945/ajcn.114.096701

Citation
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2:57 PM | Today Is World Tuberculosis Day
Robert Koch identified the tuberculosis bacterium, and is the founder of modern bacteriology – but his story also has a dark chapter. In the summer of 1890, the award-winning physician felt under pressure. Eight years earlier, on March 24, 1882, he had announced that he had identified Mycobacterium tuberculosis. This is why the World Health […]
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1:15 PM | New Snakebite Antidote Borrows from Opossum's Immunity
The humble marsupial's immunity to snake venom underpins a new potential antidote.
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1:00 PM | Angelina Jolie Has Ovaries Removed Over Cancer Fears
Although tests showed she was not in the early stages of cancer, Jolie said she chose to go ahead with the surgery because of her family history.
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10:00 AM | Dr. Hidaeka Tsuda demonstrates that antineoplastons don’t work against colon cancer
Two things have reminded me that it’s been a while since I’ve written about Stanislaw Burzynski, nearly five months, to be precise. First, on Wednesday evening I’ll be heading to the city where Burzynski preys on unsuspecting cancer patients, Houston, TX, to attend this year’s Society of Surgical Oncology meeting to imbibe the latest research…
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