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Posts

April 19, 2014

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11:55 PM | Morsels For The Mind – 18/04/2014
Every day we provide you with Six Incredible Things Before Breakfast to nibble away at. Here you can fill your brain with the most intellectually stimulating “amuse bouches” from the past week – a veritable smorgasbord for the cranium. They’re all here for you to load up your plate – this week’s “Morsels for the mind”. Enjoy! If you do nothing else, make sure to check out the “Reads / views / listens of the week”. **** Feather, fur […]
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11:55 PM | Morsels For The Mind – 18/04/2014
Every day we provide you with Six Incredible Things Before Breakfast to nibble away at. Here you can fill your brain with the most intellectually stimulating “amuse bouches” from the past week – a veritable smorgasbord for the cranium. They’re all here for you to load up your plate – this week’s “Morsels for the mind”. Enjoy! If you do nothing else, make sure to check out the “Reads / views / listens of the week”. **** Feather, fur […]
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8:25 PM | Brains Anti-Distraction System Found
So once my Grandmother… oh wait sorry, I was distracted while typing. As it turns out I’m not the only one. But there is hope, two Psychologists at Simon Fraser University […]

Gaspar J.M. & McDonald J.J. (2014). Suppression of Salient Objects Prevents Distraction in Visual Search, Journal of Neuroscience, 34 (16) 5658-5666. DOI:

Citation
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8:25 PM | Brains Anti-Distraction System Found
So once my Grandmother… oh wait sorry, I was distracted while typing. As it turns out I’m not the only one. But there is hope, two Psychologists at Simon Fraser University […]

Gaspar J.M. & McDonald J.J. (2014). Suppression of Salient Objects Prevents Distraction in Visual Search, Journal of Neuroscience, 34 (16) 5658-5666. DOI:

Citation
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11:29 AM | Typing Method for Cryptosporidium Meleagridis
We recently developed a highly applicable method for typing of Cryptosporidium meleagridis isolates. C. meleagridis is the third most common species involved in human cryptosporidiosis, a dirrhoeal disease taking a major toll on global health. Molecular typing of Cryptosporidium is critical to understanding transmission and identifying outbreaks. Until now, no robust method has been available […]

Kotloff KL, Nataro JP, Blackwelder WC, Nasrin D, Farag TH, Panchalingam S, Wu Y, Sow SO, Sur D, Breiman RF & Faruque AS (2013). Burden and aetiology of diarrhoeal disease in infants and young children in developing countries (the Global Enteric Multicenter Study, GEMS): a prospective, case-control study., Lancet, 382 (9888) 209-22. PMID:

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11:29 AM | Typing Method for Cryptosporidium Meleagridis
We recently developed a highly applicable method for typing of Cryptosporidium meleagridis isolates. C. meleagridis is the third most common species involved in human cryptosporidiosis, a dirrhoeal disease taking a major toll on global health. Molecular typing of Cryptosporidium is critical to understanding transmission and identifying outbreaks. Until now, no robust method has been available […]

Kotloff KL, Nataro JP, Blackwelder WC, Nasrin D, Farag TH, Panchalingam S, Wu Y, Sow SO, Sur D, Breiman RF & Faruque AS (2013). Burden and aetiology of diarrhoeal disease in infants and young children in developing countries (the Global Enteric Multicenter Study, GEMS): a prospective, case-control study., Lancet, 382 (9888) 209-22. PMID:

Citation
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9:34 AM | Dump fossil fuels for the health of our hearts
Cleaning up air pollution will provide immediate health gains as well as longer-term climate benefits, highlights New York University's George Thurston

Pope, C. (2003). Cardiovascular Mortality and Long-Term Exposure to Particulate Air Pollution: Epidemiological Evidence of General Pathophysiological Pathways of Disease, Circulation, 109 (1) 71-77. DOI:

Smith, K., Jerrett, M., Anderson, H., Burnett, R., Stone, V., Derwent, R., Atkinson, R., Cohen, A., Shonkoff, S., Krewski, D. & Pope, C. (2009). Public health benefits of strategies to reduce greenhouse-gas emissions: health implications of short-lived greenhouse pollutants, The Lancet, 374 (9707) 2091-2103. DOI:

Horton, D., Harshvardhan, . & Diffenbaugh, N. (2012). Response of air stagnation frequency to anthropogenically enhanced radiative forcing, Environmental Research Letters, 7 (4) 44034. DOI:

Kelly, J., Makar, P. & Plummer, D. (2012). Projections of mid-century summer air-quality for North America: effects of changes in climate and precursor emissions, Atmospheric Chemistry and Physics Discussions, 12 (2) 3875-3940. DOI:

Thurston, G. (2013). Mitigation policy: Health co-benefits, Nature Climate Change, 3 (10) 863-864. DOI:

Rice, M., Thurston, G., Balmes, J. & Pinkerton, K. (2014). Climate Change. A Global Threat to Cardiopulmonary Health, American Journal of Respiratory and Critical Care Medicine, 189 (5) 512-519. DOI:

Citation
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9:34 AM | Dump fossil fuels for the health of our hearts
Cleaning up air pollution will provide immediate health gains as well as longer-term climate benefits, highlights New York University's George Thurston

Pope, C. (2003). Cardiovascular Mortality and Long-Term Exposure to Particulate Air Pollution: Epidemiological Evidence of General Pathophysiological Pathways of Disease, Circulation, 109 (1) 71-77. DOI:

Smith, K., Jerrett, M., Anderson, H., Burnett, R., Stone, V., Derwent, R., Atkinson, R., Cohen, A., Shonkoff, S., Krewski, D. & Pope, C. (2009). Public health benefits of strategies to reduce greenhouse-gas emissions: health implications of short-lived greenhouse pollutants, The Lancet, 374 (9707) 2091-2103. DOI:

Horton, D., Harshvardhan, . & Diffenbaugh, N. (2012). Response of air stagnation frequency to anthropogenically enhanced radiative forcing, Environmental Research Letters, 7 (4) 44034. DOI:

Kelly, J., Makar, P. & Plummer, D. (2012). Projections of mid-century summer air-quality for North America: effects of changes in climate and precursor emissions, Atmospheric Chemistry and Physics Discussions, 12 (2) 3875-3940. DOI:

Thurston, G. (2013). Mitigation policy: Health co-benefits, Nature Climate Change, 3 (10) 863-864. DOI:

Rice, M., Thurston, G., Balmes, J. & Pinkerton, K. (2014). Climate Change. A Global Threat to Cardiopulmonary Health, American Journal of Respiratory and Critical Care Medicine, 189 (5) 512-519. DOI:

Citation
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9:34 AM | Dump fossil fuels for the health of our hearts
Cleaning up air pollution will provide immediate health gains as well as longer-term climate benefits, highlights New York University's George Thurston

Pope, C. (2003). Cardiovascular Mortality and Long-Term Exposure to Particulate Air Pollution: Epidemiological Evidence of General Pathophysiological Pathways of Disease, Circulation, 109 (1) 71-77. DOI:

Smith, K., Jerrett, M., Anderson, H., Burnett, R., Stone, V., Derwent, R., Atkinson, R., Cohen, A., Shonkoff, S., Krewski, D. & Pope, C. (2009). Public health benefits of strategies to reduce greenhouse-gas emissions: health implications of short-lived greenhouse pollutants, The Lancet, 374 (9707) 2091-2103. DOI:

Horton, D., Harshvardhan, . & Diffenbaugh, N. (2012). Response of air stagnation frequency to anthropogenically enhanced radiative forcing, Environmental Research Letters, 7 (4) 44034. DOI:

Kelly, J., Makar, P. & Plummer, D. (2012). Projections of mid-century summer air-quality for North America: effects of changes in climate and precursor emissions, Atmospheric Chemistry and Physics Discussions, 12 (2) 3875-3940. DOI:

Thurston, G. (2013). Mitigation policy: Health co-benefits, Nature Climate Change, 3 (10) 863-864. DOI:

Rice, M., Thurston, G., Balmes, J. & Pinkerton, K. (2014). Climate Change. A Global Threat to Cardiopulmonary Health, American Journal of Respiratory and Critical Care Medicine, 189 (5) 512-519. DOI:

Citation
+
9:34 AM | Dump fossil fuels for the health of our hearts
Cleaning up air pollution will provide immediate health gains as well as longer-term climate benefits, highlights New York University's George Thurston

Pope, C. (2003). Cardiovascular Mortality and Long-Term Exposure to Particulate Air Pollution: Epidemiological Evidence of General Pathophysiological Pathways of Disease, Circulation, 109 (1) 71-77. DOI:

Smith, K., Jerrett, M., Anderson, H., Burnett, R., Stone, V., Derwent, R., Atkinson, R., Cohen, A., Shonkoff, S., Krewski, D. & Pope, C. (2009). Public health benefits of strategies to reduce greenhouse-gas emissions: health implications of short-lived greenhouse pollutants, The Lancet, 374 (9707) 2091-2103. DOI:

Horton, D., Harshvardhan, . & Diffenbaugh, N. (2012). Response of air stagnation frequency to anthropogenically enhanced radiative forcing, Environmental Research Letters, 7 (4) 44034. DOI:

Kelly, J., Makar, P. & Plummer, D. (2012). Projections of mid-century summer air-quality for North America: effects of changes in climate and precursor emissions, Atmospheric Chemistry and Physics Discussions, 12 (2) 3875-3940. DOI:

Thurston, G. (2013). Mitigation policy: Health co-benefits, Nature Climate Change, 3 (10) 863-864. DOI:

Rice, M., Thurston, G., Balmes, J. & Pinkerton, K. (2014). Climate Change. A Global Threat to Cardiopulmonary Health, American Journal of Respiratory and Critical Care Medicine, 189 (5) 512-519. DOI:

Citation
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4:46 AM | Energy Expenditure (Calories Burned) in Anorexia Nervosa Patients
How many calories do patients with anorexia nervosa need to eat to gain a kilo (2.2 lbs)? It seems like a simple question and one that we should have figured out a long time ago, given the importance (err, necessity) of refeeding and weight restoration in recovery from anorexia nervosa. Unfortunately, research in this area has often led to contradictory results (see Salisbury et al., 1995 and de Zwaan et al., 2002 for reviews). Fortunately, a paper by Stephan Zipfel and colleagues […]

Zipfel S, Mack I, Baur LA, Hebebrand J, Touyz S, Herzog W, Abraham S, Davies PS & Russell J (2013). Impact of exercise on energy metabolism in anorexia nervosa., Journal of Eating Disorders, 1 (1) 37. PMID:

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April 18, 2014

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3:00 PM | 1 in 20 Misdiagnosed by Doctors: 10 things you can do about it
A new study out this week says that 1 in 20 adults will be misdiagnosed in outpatient clinics in the US. Thats roughly 12 million people each year, if that […]

Singh H., Meyer A.N.D. & Thomas E.J. The frequency of diagnostic errors in outpatient care: estimations from three large observational studies involving US adult populations, BMJ Quality & Safety, DOI:

Citation
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3:00 PM | 1 in 20 Misdiagnosed by Doctors: 10 things you can do about it
A new study out this week says that 1 in 20 adults will be misdiagnosed in outpatient clinics in the US. Thats roughly 12 million people each year, if that […]

Singh H., Meyer A.N.D. & Thomas E.J. The frequency of diagnostic errors in outpatient care: estimations from three large observational studies involving US adult populations, BMJ Quality & Safety, DOI:

Citation
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3:00 PM | 1 in 20 Misdiagnosed by Doctors: 10 things you can do about it
A new study out this week says that 1 in 20 adults will be misdiagnosed in outpatient clinics in the US. Thats roughly 12 million people each year, if that […]

Singh H., Meyer A.N.D. & Thomas E.J. The frequency of diagnostic errors in outpatient care: estimations from three large observational studies involving US adult populations, BMJ Quality & Safety, DOI:

Citation
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3:00 PM | 1 in 20 Misdiagnosed by Doctors: 10 things you can do about it
A new study out this week says that 1 in 20 adults will be misdiagnosed in outpatient clinics in the US. Thats roughly 12 million people each year, if that […]

Singh H., Meyer A.N.D. & Thomas E.J. The frequency of diagnostic errors in outpatient care: estimations from three large observational studies involving US adult populations, BMJ Quality & Safety, DOI:

Citation
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2:03 PM | Glucosidase I: Could targeting N-linked glycosylation of proteins help us fight viral infection?
Viruses are sneaky.  As you probably already know from your last bout with the common cold or the flu, for most viral infections doctors will simply prescribe plenty of water and […]

Sadat, M., Moir, S., Chun, T., Lusso, P., Kaplan, G., Wolfe, L., Memoli, M., He, M., Vega, H., Kim, L. & Huang, Y. (2014). Glycosylation, Hypogammaglobulinemia, and Resistance to Viral Infections, New England Journal of Medicine, 2147483647. DOI:

Herscovics, A. (1999). Importance of glycosidases in mammalian glycoprotein biosynthesis, Biochimica et Biophysica Acta (BBA) - General Subjects, 1473 (1) 96-107. DOI:

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2:03 PM | Glucosidase I: Could targeting N-linked glycosylation of proteins help us fight viral infection?
Viruses are sneaky.  As you probably already know from your last bout with the common cold or the flu, for most viral infections doctors will simply prescribe plenty of water and […]

Sadat, M., Moir, S., Chun, T., Lusso, P., Kaplan, G., Wolfe, L., Memoli, M., He, M., Vega, H., Kim, L. & Huang, Y. (2014). Glycosylation, Hypogammaglobulinemia, and Resistance to Viral Infections, New England Journal of Medicine, 2147483647. DOI:

Herscovics, A. (1999). Importance of glycosidases in mammalian glycoprotein biosynthesis, Biochimica et Biophysica Acta (BBA) - General Subjects, 1473 (1) 96-107. DOI:

Citation
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1:31 PM | Faking Sick for a Living
(This post was first published in January 2014.) Lying to your doctor is encouraged in one situation: when your doctor is a student and you’re an actor asked to portray a certain condition. My friend Amy Savage does this for work. In between fake symptom bouts, I asked her to write a guest post sharing what she’s […]The post Faking Sick for a Living appeared first on Inkfish.
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1:30 PM | Ad hominem and harassment: How antivaccine activists work
For some reason, I was really beat last night, and, given that this weekend is a holiday for a large proportion of the country (if, perhaps, not for a large proportion of my readership), I don’t feel too bad about slacking off a bit by mentioning a couple of short bits that I wanted to…
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10:30 AM | Best of Our Blogs: April 18, 2014
When your heart sinks from disappointment, rejection, or loss, how do you cope? Do you get engulfed in it falling into a pool of despair? Do you see it as a single moment or an example of more dark ones to come? Is it possible that your latest challenge has a deeper purpose? Could there […]
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10:00 AM | Lost in Space
In sci-fi films we often see people being sucked out of their spaceship by holes blown in walls, but what really happens to us in space when we leave behind the essentials? As a carbon-based life form adapted to Earth’s conditions, we’re not suited to fleeing off into space armed only with the ability to …

April 17, 2014

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7:29 PM | Research on flies suggests that lost stem cells are naturally replaced by non-stem cells
Erika MatunisCreditJohns Hopkins researchers have discovered an unexpected phenomenon in the organs that produce sperm in fruit flies, when a certain kind of stem cell is killed off experimentally, another group of non-stem cells can come out of retirement to replace them.The discovery sheds light on the tiny "environments" that stem cells occupy in animal bodies and may help explain how stem cells in tumors replenish themselves, the researchers report in the May 8 issue of the journal Cell […]

Phylis Hétié, Margaret de Cuevas, Erika Matunis (2014). Conversion of Quiescent Niche Cells to Somatic Stem Cells Causes Ectopic Niche Formation in the Drosophila Testis, Cell Reports, Other: http://dx.doi.org/10.1016/j.celrep.2014.03.058

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7:17 PM | Mesenchymal stem cells require hydrogen sulfide to function properly
Professor Songtao ShiMesenchymal stem cells need to produce hydrogen sulfide in order to properly multiply and form bone tissue, according to a new study from the Center for Craniofacial Molecular Biology at the Ostrow School of Dentistry.Professor Songtao Shi, principal investigator on the project, said the presence of hydrogen sulfide produced by the cells governs the flow of calcium ions. The essential ions activate a chain of cellular signals that results in osteogenesis, or the creation of […]

Liu, Y., Yang, R., Liu, X., Zhou, Y., Qu, C., Kikuiri, T., Wang, S., Zandi, E., Du, J., Ambudkar, I. & Shi, S. (2014). Hydrogen Sulfide Maintains Mesenchymal Stem Cell Function and Bone Homeostasis via Regulation of Ca2+ Channel Sulfhydration, Cell Stem Cell, DOI:

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4:00 PM | Five [Medical] lies the TV told me
Fad diets, miracle weight loss super foods, and vaccines! Oh my! We live in the information age, a time where webMD will tell me what kind of cancer I am suffering […]
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1:30 PM | Stanislaw Burzynski publishes 42.5% of one clinical trial
Damn it. After hearing the horrible news that Laura Hymas had died on the same day that I found out that the pro-quackery “health freedom” Alliance for Natural Health (ANH) was supporting a federal “right to try” bill, I thought it would just be a one-off post about Burzynski, his allies, and the human toll…
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11:32 AM | Cannabis use and structural changes in the brain
  “One or two spliffs a week could mess up your brain” – Metro, 16 April 2014 Spark your interest? This headline caught the eyes of the Antisense team, so […]

Gilman, J., Kuster, J., Lee, S., Lee, M., Kim, B., Makris, N., van der Kouwe, A., Blood, A. & Breiter, H. (2014). Cannabis Use Is Quantitatively Associated with Nucleus Accumbens and Amygdala Abnormalities in Young Adult Recreational Users, Journal of Neuroscience, 34 (16) 5529-5538. DOI:

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10:29 AM | Modified stem cells may offer treatment for Alzheimer's disease
Mathew Blurton-JonesUC Irvine neurobiologists have found that genetically modified neural stem cells show positive results when transplanted into the brains of mice with the symptoms and pathology of Alzheimer's disease. The pre-clinical trial is published in the journal Stem Cells Research and Therapy, and the approach has been shown to work in two different mouse models.Alzheimer's disease, one of the most common forms of dementia, is associated with accumulation of the protein amyloid-beta […]

Blurton-Jones, M., Spencer, B., Michael, S., Castello, N., Agazaryan, A., Davis, J., Müller, F., Loring, J., Masliah, E. & LaFerla, F. & (2014). Neural stem cells genetically-modified to express neprilysin reduce pathology in Alzheimer transgenic models, Stem Cell Research & Therapy, 5 (2) 46. DOI:

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9:46 AM | New Journal: Canine Genetics and Epidemiology
  There is a new peer-review, open access journal focusing on all things related to canine genetics and epidemiology.  Over this blog’s history I’ve had to mine everything from Journal of Nucleic Acid research to the Journal of Biophysical Chemistry, not publications one thinks of when the subject of behavior or health pop to mind. I think it’s…
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8:31 AM | Mitochondrial dysfunction as a neurobiological subtype of autism
The paper by Suzanne Goh and colleagues [1] reporting on "a possible neurobiological subtype of mitochondrial dysfunction in ASD [autism spectrum disorder]" is a worthy addition to the research roll call which has graced this blog down the years. Based on the analysis of brain lactate levels - a potential marker of mitochondrial dysfunction - via the analysis of lactate doublets on brain magnetic resonance spectroscopic imaging (MRSI), authors picked up a significantly higher rate of […]

Goh, S., Dong, Z., Zhang, Y., DiMauro, S. & Peterson, B. (2014). Mitochondrial Dysfunction as a Neurobiological Subtype of Autism Spectrum Disorder, JAMA Psychiatry, DOI:

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8:29 AM | A global network of researchers? Not really – small worlds.
The high clustering coefficient coupled with a short average distance between nodes suggests a "small-world phenomenon" among HIV and HPV researchers. The post A global network of researchers? Not really – small worlds. appeared first on MicrobiologyBytes.
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