Posts

November 27, 2014

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3:00 AM | Survival of the Nicest: How Altruism Made Us Human and Why It Pays to Get Along
By Stefan Klein Synopsis: This revelatory tour de force by an acclaimed and internationally bestselling science writer upends our understanding of “survival of the fittest”—and invites us all to think and act more altruistically. The phrase […]

November 26, 2014

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8:20 PM | Need to turn off the pain? Well now we can!
 My sister suffers from chronic pain issues. I’ve written several posts about how her autoimmune disease is a special brand of pain that you will thankfully (almost certainly) never have […]

Little JW, Ford A, Symons-Liguori AM, Chen Z, Janes K, Doyle T, Xie J, Luongo L, Tosh DK, Maione S & Bannister K (2014). Endogenous adenosine A3 receptor activation selectively alleviates persistent pain states., Brain : a journal of neurology, PMID: http://www.ncbi.nlm.nih.gov/pubmed/25414036

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Editor's Pick
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8:20 PM | Need to turn off the pain? Well now we can!
 My sister suffers from chronic pain issues. I’ve written several posts about how her autoimmune disease is a special brand of pain that you will thankfully (almost certainly) never have […]

Little JW, Ford A, Symons-Liguori AM, Chen Z, Janes K, Doyle T, Xie J, Luongo L, Tosh DK, Maione S & Bannister K (2014). Endogenous adenosine A3 receptor activation selectively alleviates persistent pain states., Brain : a journal of neurology, PMID: http://www.ncbi.nlm.nih.gov/pubmed/25414036

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Editor's Pick
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6:45 PM | Long-Lost Turkey Bacteria May Bring New Antibiotics
'Good' bacteria inside the holiday food favorite produces medicine that can kill roughly half of all infectious bacteria.
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11:55 AM | Lab-grown spinal cords
Researchers in Germany have grown complete spinal cords in a Petri dish. As regenerative medicine and stem cell technologies continue to progress, so the list of tissues and organs that can be grown from scratch – and potentially replaced – continues to grow. In the past few years, researchers have used stem cells to grow windpipes, bladders, urethras and vaginas in the lab, and, in some cases, successfully transplanted them into patients.Others are making progress in growing liver […]
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11:32 AM | How to heal paralysis: modern day miracles
Without doubt, Geoffrey Raisman is in line for a Nobel Prize. The little-known British professor has been the brains behind a breakthrough that ‘cured’ a paraplegic man. Bulgarian Darek Fidyka was left paralysed after a knife attack four years ago; images of him now standing upright shot across the globe a few weeks ago. For … Continue reading →
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11:00 AM | Can you destroy a meter other than an irony meter?
I don’t think I mentioned this, but I’m on a bit of a staycation this week. I figured, what the heck? After coming home from Skepticon I could do with a little R&R. Of course, fool that I am, I still can’t resist blogging a bit. On the other hand, the day before Thanksgiving I…
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9:54 AM | The gut microbiome in Down Syndrome
The recent preliminary findings from Elena Biagi and colleagues [1] (open-access) reporting on the constitution of the gut microbiome - the collected bacteria which reside in the deepest, darkest recesses of our gastrointestinal (GI) tract - in a small number of cases of Down's syndrome caught my eye recently.It's a funny feeling being taken under the wing of a dragonPerhaps a little bit unusually looking at the gut microbiome because of the link between premature ageing in Down's syndrome […]

Biagi E, Candela M, Centanni M, Consolandi C, Rampelli S, Turroni S, Severgnini M, Peano C, Ghezzo A, Scurti M & Salvioli S (2014). Gut Microbiome in Down Syndrome., PloS one, 9 (11) PMID: http://www.ncbi.nlm.nih.gov/pubmed/25386941

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November 25, 2014

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8:38 PM | Is Milk Really All That Good For You?
Would it surprise you to find out that most people are lactose-intolerant? Most mammals (including humans) drink milk at a young age, but as we start to grow older, our bodies begin to stop digesting lactose properly. According to the National Library of Medicine, approximately 65% of people on the planet have trouble digesting milk. For these people, drinking milk can cause constipation, acid-reflex, migraines, increased eczema, and even joint pain! But we’ve all seen those ads on TV […]
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7:38 PM | The Chemistry of Asthma Inhalers
If you’re an asthma sufferer, you likely need at least one inhaler to keep your symptoms in check – or maybe even two different types. Commonly, those afflicted with asthma will have both a blue and a brown inhaler. Whilst the colours can vary, the purpose of the chemical compounds contained therein differ dependent on […]
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6:18 PM | Oy. I worry about this with cell line studies a lot. Mis-IDed + contaminated.
Via NCBI Announce mailing list: NCBI BioSample includes curated list of over 400 known misidentified and contaminated cell lines The NCBI BioSample database now includes a curated list of over 400 known misidentified and contaminated cell lines. Scientists should check this list before they start working with a new cell line to see if that cell line […]

A.T.C.C.S.D.O.W.A.0. (2010). Cell line misidentification: the beginning of the end, Nature Reviews Cancer, 10 (6) 441-448. DOI: http://dx.doi.org/10.1038/nrc2852

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3:00 PM | The invasion of well-meaning quacks into West Africa continues apace, part deux
I realize that I risk getting repetitive by writing about this again, but it’s a rich vein that just keeps on producing and producing. It also demonstrates that, for every tragedy as huge as the ongoing Ebola outbreak that has killed over 5,000 people in West Africa thus far, there always exist well-meaning people who…
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2:20 PM | "Throckmorton Sign" Is A Rather Naughty Medical Condition
Here's a hint as to what the Throckmorton Sign is. It's also known as the John Thomas Sign, and it's going to make the x-ray in this entry ever so slightly not safe for work. Read more...
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12:29 PM | Consuming raw or undercooked frogs may increase your risk of getting a rare tapeworm in your brain
A 50-year-old UK resident had been living with an unwelcome visitor for the past 4 years and it was such a headache. Surgeons from Addenbrooke’s Hospital in Cambridge removed the tapeworm during a biopsy after noticing a small circular lesion … Continue reading →
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11:00 AM | Diabetes Awareness Month
Assistant Editor Inez Imray tells us about November as the National Diabetes Awareness month. With Halloween officially over, most of us will now be spending the next month getting ready for the festive season! November always seems to be remarkably easy to forget about. Many of us celebrated Bonfire Night but what else is there? Actually,…
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8:20 AM | Serotonin - melatonin (and the in-betweeners) linked to autism
The paper by Pagan and colleagues [1] (open-access) looking at "serotonin, melatonin and the intermediate N-acetylserotonin (NAS) in a large cohort of patients with ASD [autism spectrum disorder] and their relatives" set the old grey-pink matter into action recently. Not only because I have some real interest in the starting material for these compounds - the aromatic amino acid known as tryptophan - but because this research group included some quite important analysis of the […]

Pagan C, Delorme R, Callebert J, Goubran-Botros H, Amsellem F, Drouot X, Boudebesse C, Le Dudal K, Ngo-Nguyen N, Laouamri H & Gillberg C (2014). The serotonin-N-acetylserotonin-melatonin pathway as a biomarker for autism spectrum disorders., Translational psychiatry, 4 PMID: http://www.ncbi.nlm.nih.gov/pubmed/25386956

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November 24, 2014

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8:26 PM | Hiding cells to prevent HIV transmission
The fight against HIV is ongoing and despite our rapid progression against the disease we still lack a cure or even adequate treatment for people infected. However, new research suggests […]

Byrareddy, S., Kallam, B., Arthos, J., Cicala, C., Nawaz, F., Hiatt, J., Kersh, E., McNicholl, J., Hanson, D., Reimann, K. & Brameier, M. (2014). Targeting α4β7 integrin reduces mucosal transmission of simian immunodeficiency virus and protects gut-associated lymphoid tissue from infection, Nature Medicine, DOI: 10.1038/nm.3715

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8:26 PM | Hiding cells to prevent HIV transmission
The fight against HIV is ongoing and despite our rapid progression against the disease we still lack a cure or even adequate treatment for people infected. However, new research suggests […]

Byrareddy, S., Kallam, B., Arthos, J., Cicala, C., Nawaz, F., Hiatt, J., Kersh, E., McNicholl, J., Hanson, D., Reimann, K. & Brameier, M. (2014). Targeting α4β7 integrin reduces mucosal transmission of simian immunodeficiency virus and protects gut-associated lymphoid tissue from infection, Nature Medicine, DOI: 10.1038/nm.3715

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8:26 PM | Hiding cells to prevent HIV transmission
The fight against HIV is ongoing and despite our rapid progression against the disease we still lack a cure or even adequate treatment for people infected. However, new research suggests […]

Byrareddy, S., Kallam, B., Arthos, J., Cicala, C., Nawaz, F., Hiatt, J., Kersh, E., McNicholl, J., Hanson, D., Reimann, K. & Brameier, M. (2014). Targeting α4β7 integrin reduces mucosal transmission of simian immunodeficiency virus and protects gut-associated lymphoid tissue from infection, Nature Medicine, DOI: 10.1038/nm.3715

Citation
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8:26 PM | Hiding cells to prevent HIV transmission
The fight against HIV is ongoing and despite our rapid progression against the disease we still lack a cure or even adequate treatment for people infected. However, new research suggests […]

Byrareddy, S., Kallam, B., Arthos, J., Cicala, C., Nawaz, F., Hiatt, J., Kersh, E., McNicholl, J., Hanson, D., Reimann, K. & Brameier, M. (2014). Targeting α4β7 integrin reduces mucosal transmission of simian immunodeficiency virus and protects gut-associated lymphoid tissue from infection, Nature Medicine, DOI: 10.1038/nm.3715

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12:03 PM | Garlic for the common cold
Can garlic cure the common cold? Continue reading →
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11:30 AM | Cracked Science Video 4: Irreproducible
We often hear the science corrects itself in the long run, but how efficient is this mechanism? Jonathan Jarry reports that reproducibility in the scientific literature is not always a given. (Des sous-titres en français seront bientôt disponibles!) Just so you are not too demoralized, the landscape may be changing: http://www.nature.com/news/journals-u… http://www.nature.com/news/metascienc… Continue reading →
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11:00 AM | Prolonged Marijuana Use Linked with Brain Changes
Using marijuana daily for four years or longer may be related to certain changes in the brain, according to new research.
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10:15 AM | Helicobacter pylori and stem cells in the gastric crypt
Last Friday, the 4th Integrated Mathematical Oncology Workshop finished here at Moffitt. The event drew a variety of internal and external participants — you can see a blurry photo of many of them above — and was structured as a competition between four teams specializing in four different domains: Microbiome, Hepatitis C, Human papillomavirus, and […]

Houghton, J., Stoicov, C., Nomura, S., Rogers, A.B., Carlson, J., Li, H., Cai, X., Fox, J.G., Goldenring, J.R. & Wang, T.C. & (2004). Gastric cancer originating from bone marrow-derived cells., Science, 306 (5701) 1568-71. PMID: http://www.ncbi.nlm.nih.gov/pubmed/15567866

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November 22, 2014

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9:08 PM | Morsels For The Mind – 21/11/2014
Every day we provide you with Six Incredible Things Before Breakfast to nibble away at. Here you can fill your brain with the most intellectually stimulating “amuse bouches” from the past week – a veritable smorgasbord for the cranium. They’re all here for you to load up your plate – this week’s “Morsels for the mind”. Enjoy! If you do nothing else, make sure to check out the “Reads / views / listens of the week”. This week: Deeply […]
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9:08 PM | Morsels For The Mind – 21/11/2014
Every day we provide you with Six Incredible Things Before Breakfast to nibble away at. Here you can fill your brain with the most intellectually stimulating “amuse bouches” from the past week – a veritable smorgasbord for the cranium. They’re all here for you to load up your plate – this week’s “Morsels for the mind”. Enjoy! If you do nothing else, make sure to check out the “Reads / views / listens of the week”. This week: Deeply […]
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7:45 PM | Mental Health- The invisible barrier for women’s care
A while back I wrote a post about mental health and jail sentences, it seems like no one takes mental health seriously and that leads to lack of care for […]

Xiang, X. (2014). Serious Psychological Distress as a Barrier to Cancer Screening Among Women, Women's Health Issues, DOI: 10.1016/j.whi.2014.09.001

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7:45 PM | Mental Health- The invisible barrier for women’s care
A while back I wrote a post about mental health and jail sentences, it seems like no one takes mental health seriously and that leads to lack of care for […]

Xiang, X. (2014). Serious Psychological Distress as a Barrier to Cancer Screening Among Women, Women's Health Issues, DOI: 10.1016/j.whi.2014.09.001

Citation
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7:45 PM | Mental Health- The invisible barrier for women’s care
A while back I wrote a post about mental health and jail sentences, it seems like no one takes mental health seriously and that leads to lack of care for […]

Xiang, X. (2014). Serious Psychological Distress as a Barrier to Cancer Screening Among Women, Women's Health Issues, DOI: 10.1016/j.whi.2014.09.001

Citation
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7:45 PM | Mental Health- The invisible barrier for women’s care
A while back I wrote a post about mental health and jail sentences, it seems like no one takes mental health seriously and that leads to lack of care for […]

Xiang, X. (2014). Serious Psychological Distress as a Barrier to Cancer Screening Among Women, Women's Health Issues, DOI: 10.1016/j.whi.2014.09.001

Citation
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