Posts

July 30, 2014

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8:52 AM | Immunological effects from risperidone treatment in autism
The findings from Jai Eun Choi and colleagues [1] suggesting that use of the antipsychotic risperidone may impact on levels of certain cytokines - messenger cells of the immune system - in some cases of autism spectrum disorder (ASD) grabbed my attention recently. I've always been pretty interested in the complexity of the immune system when it comes to something like autism (see here) as well as the various examples of how many of the medications used to 'manage' aspects of […]

Choi JE, Widjaja F, Careaga M, Bent S, Ashwood P & Hendren RL (2014). Change in Plasma Cytokine Levels During Risperidone Treatment in Children with Autism., Journal of child and adolescent psychopharmacology, PMID: http://www.ncbi.nlm.nih.gov/pubmed/24828014

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7:00 AM | Women, antibiotics and the Longitude Prize | Athene Donald
Athene Donald: Times have changed since the first Longitude Prize and women now form an important part of the scientific workforce. Can the resultant diversity help to find creative solutions to this challenge prize?Across the world many leaders are speaking out about the challenges our global society faces as antibiotic resistance grows and our medical arsenal to defeat infection shrinks. In the last few months the World Health Organization (WHO), David Cameron and Sally Davies (the UKs Chief […]

July 29, 2014

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8:15 PM | Pseudoaccomodation in Pseudophakes
If you’ve kept up with the literature about pseudophakes, you are probably already familiar with the study by Plotkinov and friends: “Objective assessment of pseudoaccommodation in pseudophakia” [article in Russian], I.A. Plotnikov, V. M. Sheludenko, and N. P. Narbut, Vestnik oftalmologii, vol. 123, no. 6 (2006): 35-37. BONUS: Also from the year 2006, Tarek Abd El-Basset […]
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7:07 PM | How a Mysterious Body Part Called Fascia Is Challenging Medicine
Fascia is a web of fibrous tissue that permeates the body, but is it really the "Cinderella Tissue" that new age therapists, Rolfers, and yoga instructors suggest? The fascial system is still a medical mystery. But that could soon change, thanks to an unlikely alliance between researchers and alternative therapists.Read more...
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5:15 PM | Can’t Handle the Stress? Blame your Brain
Do you rise to the occasion, or do you fold under the pressure? No matter which side of the fence you’re, you can thank [or blame] your brain. Some people […]

Kumar, S., Hultman, R., Hughes, D., Michel, N., Katz, B. & Dzirasa, K. (2014). Prefrontal cortex reactivity underlies trait vulnerability to chronic social defeat stress, Nature Communications, 5 DOI: 10.1038/ncomms5537

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5:15 PM | Can’t Handle the Stress? Blame your Brain
Do you rise to the occasion, or do you fold under the pressure? No matter which side of the fence you’re, you can thank [or blame] your brain. Some people […]

Kumar, S., Hultman, R., Hughes, D., Michel, N., Katz, B. & Dzirasa, K. (2014). Prefrontal cortex reactivity underlies trait vulnerability to chronic social defeat stress, Nature Communications, 5 DOI: 10.1038/ncomms5537

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7:02 AM | Déjà vu all over again: “Natural medicine” wikis
Regular readers will know that über-quack Mike Adams got himself into a bit of a pickle last week. Basically, he wrote a now-infamous post in which he likened scientists working on GMOs to Nazi scientists and pro-science bloggers refuting the sort of nonsensical fear mongering (from a scientific perspective) Adams and other anti-GMO activists like…

July 28, 2014

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5:13 PM | A New Hepatitis C Treatment offers Hope
Well this might seem weird, but today is world hepatitis day. I guess I should qualify weird with the fact that it’s only weird because no one really knows. What […]

Lawitz, E., Sulkowski, M., Ghalib, R., Rodriguez-Torres, M., Younossi, Z., Corregidor, A., DeJesus, E., Pearlman, B., Rabinovitz, M., Gitlin, N. & Lim, J. (2014). Simeprevir plus sofosbuvir, with or without ribavirin, to treat chronic infection with hepatitis C virus genotype 1 in non-responders to pegylated interferon and ribavirin and treatment-naive patients: the COSMOS randomised study, The Lancet, DOI: 10.1016/S0140-6736(14)61036-9

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5:13 PM | A New Hepatitis C Treatment offers Hope
Well this might seem weird, but today is world hepatitis day. I guess I should qualify weird with the fact that it’s only weird because no one really knows. What […]

Lawitz, E., Sulkowski, M., Ghalib, R., Rodriguez-Torres, M., Younossi, Z., Corregidor, A., DeJesus, E., Pearlman, B., Rabinovitz, M., Gitlin, N. & Lim, J. (2014). Simeprevir plus sofosbuvir, with or without ribavirin, to treat chronic infection with hepatitis C virus genotype 1 in non-responders to pegylated interferon and ribavirin and treatment-naive patients: the COSMOS randomised study, The Lancet, DOI: 10.1016/S0140-6736(14)61036-9

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5:13 PM | A New Hepatitis C Treatment offers Hope
Well this might seem weird, but today is world hepatitis day. I guess I should qualify weird with the fact that it’s only weird because no one really knows. What […]

Lawitz, E., Sulkowski, M., Ghalib, R., Rodriguez-Torres, M., Younossi, Z., Corregidor, A., DeJesus, E., Pearlman, B., Rabinovitz, M., Gitlin, N. & Lim, J. (2014). Simeprevir plus sofosbuvir, with or without ribavirin, to treat chronic infection with hepatitis C virus genotype 1 in non-responders to pegylated interferon and ribavirin and treatment-naive patients: the COSMOS randomised study, The Lancet, DOI: 10.1016/S0140-6736(14)61036-9

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2:40 PM | Elephants Might Be Able To Self-Medicate To Induce Labor
We know that animals have found ways to get themselves drunk or high by eating certain plants or fermented fruit, but recently, scientists have started studying the self-medication of animals — a branch of science dubbed zoopharmacognosy. This is how we discovered elephants might have a way to bring on labor. Read more...
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8:24 AM | Prenatal and neonatal blood mercury levels and autism
Acknowledging that some topics have the ability to furrow brows when it comes to autism research, mercury and autism is becoming something of a frequent talking point on this blog as a function of a whole slew of articles appearing in the peer-reviewed domain. If I were to [very tentatively] summarise the collected literature so far, it would be to say something like:Mosaic of mercury @ Wikipedia (i) there is quite a bit more research to be done on some sources of mercury being […]

Yau VM, Green PG, Alaimo CP, Yoshida CK, Lutsky M, Windham GC, Delorenze G, Kharrazi M, Grether JK & Croen LA & (2014). Prenatal and neonatal peripheral blood mercury levels and autism spectrum disorders., Environmental research, 133C 294-303. PMID: http://www.ncbi.nlm.nih.gov/pubmed/24981828

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July 27, 2014

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4:00 AM | Neuroscience and Creativity
Edited by Oshin Vartanian, Adam S Bristol and James C Kaufman Synopsis: This volume offers a comprehensive overview of the latest neuroscientific approaches to the scientific study of creativity. In chapters that progress logically from neurobiological […]

July 26, 2014

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8:02 PM | Morsels For The Mind – 25/07/2014
Every day we provide you with Six Incredible Things Before Breakfast to nibble away at. Here you can fill your brain with the most intellectually stimulating “amuse bouches” from the past week – a veritable smorgasbord for the cranium. They’re all here for you to load up your plate – this week’s “Morsels for the mind”. Enjoy! If you do nothing else, make sure to check out the “Reads / views / listens of the week”. **** Star Wars […]
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8:02 PM | Morsels For The Mind – 25/07/2014
Every day we provide you with Six Incredible Things Before Breakfast to nibble away at. Here you can fill your brain with the most intellectually stimulating “amuse bouches” from the past week – a veritable smorgasbord for the cranium. They’re all here for you to load up your plate – this week’s “Morsels for the mind”. Enjoy! If you do nothing else, make sure to check out the “Reads / views / listens of the week”. **** Star Wars […]
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5:18 PM | Save the Neurons: Fighting the Effects of Parkinsons
Possibly one of the most famous cases of parkinson’s is Michael J. Fox. More than just the “shakes” parkinson’s can cause a whole host of other problems mentally and physically […]

Barnum CJ, Chen X, Chung J, Chang J, Williams M, Grigoryan N, Tesi RJ & Tansey MG (2014). Peripheral Administration of the Selective Inhibitor of Soluble Tumor Necrosis Factor (TNF) XPro1595 Attenuates Nigral Cell Loss and Glial Activation in 6-OHDA Hemiparkinsonian Rats., Journal of Parkinson's disease, PMID: http://www.ncbi.nlm.nih.gov/pubmed/25061061

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5:18 PM | Save the Neurons: Fighting the Effects of Parkinsons
Possibly one of the most famous cases of parkinson’s is Michael J. Fox. More than just the “shakes” parkinson’s can cause a whole host of other problems mentally and physically […]

Barnum CJ, Chen X, Chung J, Chang J, Williams M, Grigoryan N, Tesi RJ & Tansey MG (2014). Peripheral Administration of the Selective Inhibitor of Soluble Tumor Necrosis Factor (TNF) XPro1595 Attenuates Nigral Cell Loss and Glial Activation in 6-OHDA Hemiparkinsonian Rats., Journal of Parkinson's disease, PMID: http://www.ncbi.nlm.nih.gov/pubmed/25061061

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5:18 PM | Save the Neurons: Fighting the Effects of Parkinsons
Possibly one of the most famous cases of parkinson’s is Michael J. Fox. More than just the “shakes” parkinson’s can cause a whole host of other problems mentally and physically […]

Barnum CJ, Chen X, Chung J, Chang J, Williams M, Grigoryan N, Tesi RJ & Tansey MG (2014). Peripheral Administration of the Selective Inhibitor of Soluble Tumor Necrosis Factor (TNF) XPro1595 Attenuates Nigral Cell Loss and Glial Activation in 6-OHDA Hemiparkinsonian Rats., Journal of Parkinson's disease, PMID: http://www.ncbi.nlm.nih.gov/pubmed/25061061

Citation
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5:18 PM | Save the Neurons: Fighting the Effects of Parkinsons
Possibly one of the most famous cases of parkinson’s is Michael J. Fox. More than just the “shakes” parkinson’s can cause a whole host of other problems mentally and physically […]

Barnum CJ, Chen X, Chung J, Chang J, Williams M, Grigoryan N, Tesi RJ & Tansey MG (2014). Peripheral Administration of the Selective Inhibitor of Soluble Tumor Necrosis Factor (TNF) XPro1595 Attenuates Nigral Cell Loss and Glial Activation in 6-OHDA Hemiparkinsonian Rats., Journal of Parkinson's disease, PMID: http://www.ncbi.nlm.nih.gov/pubmed/25061061

Citation
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5:18 PM | Save the Neurons: Fighting the Effects of Parkinsons
Possibly one of the most famous cases of parkinson’s is Michael J. Fox. More than just the “shakes” parkinson’s can cause a whole host of other problems mentally and physically […]

Barnum CJ, Chen X, Chung J, Chang J, Williams M, Grigoryan N, Tesi RJ & Tansey MG (2014). Peripheral Administration of the Selective Inhibitor of Soluble Tumor Necrosis Factor (TNF) XPro1595 Attenuates Nigral Cell Loss and Glial Activation in 6-OHDA Hemiparkinsonian Rats., Journal of Parkinson's disease, PMID: http://www.ncbi.nlm.nih.gov/pubmed/25061061

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1:00 PM | Françoise Barré-Sinoussi’s Fight Against AIDS
Why HIV research always has a political dimension and why a renowned researcher can also be an international political activist. To be a scientist and an activist at the same time – for Nobel laureate Barré-Sinoussi this is an inevitable combination: after decades of research on the HI virus, she has truly worked ‘for the […]

July 25, 2014

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7:34 PM | A woman who tested positive for the deadly Ebola virus has escaped quarantine and is wandering in Fr
A woman who tested positive for the deadly Ebola virus has escaped quarantine and is wandering in Freetown, Sierra Leone, a city of 1 million people. Over the past several weeks, deadly outbreaks of Ebola have killed many people in Sierra Leone and elsewhere in western Africa.Read more...
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5:47 PM | Fighting the Obesity Epidemic with X-box [No, not that one]
Despite all the efforts, people are losing the war on obesity. There is probably a number of factors involved, genetics, underlying medical problems, most of all diet, but in any […]

Williams KW, Liu T, Kong X, Fukuda M, Deng Y, Berglund ED, Deng Z, Gao Y, Liu T, Sohn JW & Jia L (2014). Xbp1s in Pomc Neurons Connects ER Stress with Energy Balance and Glucose Homeostasis., Cell metabolism, PMID: http://www.ncbi.nlm.nih.gov/pubmed/25017942

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5:47 PM | Fighting the Obesity Epidemic with X-box [No, not that one]
Despite all the efforts, people are losing the war on obesity. There is probably a number of factors involved, genetics, underlying medical problems, most of all diet, but in any […]

Williams KW, Liu T, Kong X, Fukuda M, Deng Y, Berglund ED, Deng Z, Gao Y, Liu T, Sohn JW & Jia L (2014). Xbp1s in Pomc Neurons Connects ER Stress with Energy Balance and Glucose Homeostasis., Cell metabolism, PMID: http://www.ncbi.nlm.nih.gov/pubmed/25017942

Citation
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5:47 PM | Fighting the Obesity Epidemic with X-box [No, not that one]
Despite all the efforts, people are losing the war on obesity. There is probably a number of factors involved, genetics, underlying medical problems, most of all diet, but in any […]

Williams KW, Liu T, Kong X, Fukuda M, Deng Y, Berglund ED, Deng Z, Gao Y, Liu T, Sohn JW & Jia L (2014). Xbp1s in Pomc Neurons Connects ER Stress with Energy Balance and Glucose Homeostasis., Cell metabolism, PMID: http://www.ncbi.nlm.nih.gov/pubmed/25017942

Citation
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5:47 PM | Fighting the Obesity Epidemic with X-box [No, not that one]
Despite all the efforts, people are losing the war on obesity. There is probably a number of factors involved, genetics, underlying medical problems, most of all diet, but in any […]

Williams KW, Liu T, Kong X, Fukuda M, Deng Y, Berglund ED, Deng Z, Gao Y, Liu T, Sohn JW & Jia L (2014). Xbp1s in Pomc Neurons Connects ER Stress with Energy Balance and Glucose Homeostasis., Cell metabolism, PMID: http://www.ncbi.nlm.nih.gov/pubmed/25017942

Citation
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5:47 PM | Fighting the Obesity Epidemic with X-box [No, not that one]
Despite all the efforts, people are losing the war on obesity. There is probably a number of factors involved, genetics, underlying medical problems, most of all diet, but in any […]

Williams KW, Liu T, Kong X, Fukuda M, Deng Y, Berglund ED, Deng Z, Gao Y, Liu T, Sohn JW & Jia L (2014). Xbp1s in Pomc Neurons Connects ER Stress with Energy Balance and Glucose Homeostasis., Cell metabolism, PMID: http://www.ncbi.nlm.nih.gov/pubmed/25017942

Citation
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5:47 PM | Fighting the Obesity Epidemic with X-box [No, not that one]
Despite all the efforts, people are losing the war on obesity. There is probably a number of factors involved, genetics, underlying medical problems, most of all diet, but in any […]

Williams KW, Liu T, Kong X, Fukuda M, Deng Y, Berglund ED, Deng Z, Gao Y, Liu T, Sohn JW & Jia L (2014). Xbp1s in Pomc Neurons Connects ER Stress with Energy Balance and Glucose Homeostasis., Cell metabolism, PMID: http://www.ncbi.nlm.nih.gov/pubmed/25017942

Citation
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5:40 PM | Google Wants to Create a Map of What a Healthy Human Body Looks Like
It's the ultimate baseline study — an effort to collect the fullest picture of what a healthy human being should look like. Read more...
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2:01 PM | Neurosciences: Bringing the TReND to Africa
The Lindau-alumni founded NGO TReND in Africa is dedicated to improve research conditions on the continent. Whilst studying for her PhD in neurosciences at Cambridge University, Lindau alumna, Lucia Prieto-Godino (2014, physiology/medicine), met Sadiq Yusuf and was shocked to discover “that many East African neuroscientists were still using expensive rat models for their research despite […]
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