Posts

December 22, 2014

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5:38 PM | Autism presentation and genetic variance
People with autism have a wide range of symptoms, with no two people sharing the exact type and severity of behaviors. This has made finding a cause (or causes) difficult, leaving pseudoscientists to claim vaccines are the cause as if it were that simple (hint: vaccines do not cause autism). Now a large-scale analysis of […]

Chang, J., Gilman, S., Chiang, A., Sanders, S. & Vitkup, D. (2014). Genotype to phenotype relationships in autism spectrum disorders, Nature Neuroscience, DOI: 10.1038/nn.3907

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5:38 PM | Autism presentation and genetic variance
People with autism have a wide range of symptoms, with no two people sharing the exact type and severity of behaviors. This has made finding a cause (or causes) difficult, leaving pseudoscientists to claim vaccines are the cause as if it were that simple (hint: vaccines do not cause autism). Now a large-scale analysis of […]

Chang, J., Gilman, S., Chiang, A., Sanders, S. & Vitkup, D. (2014). Genotype to phenotype relationships in autism spectrum disorders, Nature Neuroscience, DOI: 10.1038/nn.3907

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4:32 PM | Suppressing a protein reduces cancer spread in mice
Scientists have found that decreasing the levels of or blocking a specific protein commonly found in humans and many other animals allowed them to slow the spread of two different […]
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2:00 PM | Stanford Identifies Drug That May Improve Cardiac Stents
Stanford researchers believe they’ve found a drug for cardiac stents that can more effectively prevent complications, because the drug targets the actual cause of stent disease.
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1:34 PM | Lens-free microscope can detect cancer at the cellular level
UCLA researchers have developed a lens-free microscope that can be used to detect the presence of cancer or other cell-level abnormalities with the same accuracy as larger and more expensive […]
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1:17 PM | Fast-Food Consumption Linked to Lower Test Score Gains in 8th Graders
The more children ate in 5th grade, the slower their academic growth by 8th grade The amount of fast food children eat may be linked to how well they do […]
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10:48 AM | Cytokines activating the kynurenine pathway in schizophrenia?
I'm a bit of a fan of tryptophan biochemistry on this blog. This quite remarkable aromatic amino acid and it's off-shoot metabolites, which appear to have no end of biological uses, have taken quite a bit of my blogging time down the years. Most recently was the suggestion that a metabolite slotting in between serotonin (5-HT) and melatonin might require quite a bit more investigation when it comes to at least some cases of autism (see here).See ya later, President Fartfeathers.The findings […]

Schwieler L, Larsson MK, Skogh E, Kegel ME, Orhan F, Abdelmoaty S, Finn A, Bhat M, Samuelsson M, Lundberg K & Dahl ML (2014). Increased levels of IL-6 in the cerebrospinal fluid of patients with chronic schizophrenia - significance for activation of the kynurenine pathway., Journal of psychiatry & neuroscience : JPN, 39 (6) 140126. PMID: http://www.ncbi.nlm.nih.gov/pubmed/25455350

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5:20 AM | Go to Bed Early and Cure Your Negative Ruminations!
Source: Alyssa L. Miller, Flickr.For nearly 9 years, this blog has been harping on the blight of overblown press releases, with posts like:Irresponsible Press Release Gives False Hope to People With Tourette's, OCD, and SchizophreniaPress Release: Press Releases Are PrestidigitationNew research provides fresh evidence that bogus press releases may depend largely on our biological make-upSave Us From Misleading Press Releasesetc.So it was heartening to see a team of UK researchers formally […]

Nota, J. & Coles, M. (2014). Duration and Timing of Sleep are Associated with Repetitive Negative Thinking, Cognitive Therapy and Research, DOI: 10.1007/s10608-014-9651-7

Sumner, P., Vivian-Griffiths, S., Boivin, J., Williams, A., Venetis, C., Davies, A., Ogden, J., Whelan, L., Hughes, B., Dalton, B. & Boy, F. (2014). The association between exaggeration in health related science news and academic press releases: retrospective observational study, BMJ, 349 (dec09 7) DOI: 10.1136/bmj.g7015

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5:20 AM | Go to Bed Early and Cure Your Negative Ruminations!
Source: Alyssa L. Miller, Flickr.For nearly 9 years, this blog has been harping on the blight of overblown press releases, with posts like:Irresponsible Press Release Gives False Hope to People With Tourette's, OCD, and SchizophreniaPress Release: Press Releases Are PrestidigitationNew research provides fresh evidence that bogus press releases may depend largely on our biological make-upSave Us From Misleading Press Releasesetc.So it was heartening to see a team of UK researchers formally […]

Nota, J. & Coles, M. (2014). Duration and Timing of Sleep are Associated with Repetitive Negative Thinking, Cognitive Therapy and Research, DOI: 10.1007/s10608-014-9651-7

Sumner, P., Vivian-Griffiths, S., Boivin, J., Williams, A., Venetis, C., Davies, A., Ogden, J., Whelan, L., Hughes, B., Dalton, B. & Boy, F. (2014). The association between exaggeration in health related science news and academic press releases: retrospective observational study, BMJ, 349 (dec09 7) DOI: 10.1136/bmj.g7015

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12:06 AM | Nepal’s “Miracle Doctor” Has Personally Restored the Vision of More Than 100,000 People
For many of his patients, Sanduk Ruit is truly a miracle worker. Over the past 30 years, Ruit has personally restored vision to more than 100,000 people in Asia and Africa. He has also taught his simply and inexpensive methods to countless other eye surgeons across the world, in countries as remote as North Korea. The entire process takes around five minutes. The doctor makes a small incision in the patient’s eye, allowing him to remove cloudy cataracts that impair vision

December 21, 2014

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9:00 PM | Why Do We Eat Spoiled Food?
Not all spoiled food is created equal. Most everyone has an aversion to rotten foods. After all, they taste awful . But what about the foods we spoil intentionally? What separates rancid meet, for example, from moldy cheese, or bacteria-laden Salami?Read more...
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8:21 PM | Vaccine against prion disease, not for humans… yet
Prions, misfolded proteins that wreak havoc on the brain, may have finally met their match. Best known for things like mad cow disease and possibly alzheimer’s disease scientists have had no luck stopping prions, until now. Researchers say that a vaccination they have developed to fight a brain-based, wasting syndrome among deer and other animals […]

Goñi, F., Mathiason, C., Yim, L., Wong, K., Hayes-Klug, J., Nalls, A., Peyser, D., Estevez, V., Denkers, N., Xu, J. & Osborn, D. (2014). Mucosal immunization with an attenuated Salmonella vaccine partially protects white-tailed deer from chronic wasting disease, Vaccine, DOI: 10.1016/j.vaccine.2014.11.035

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8:21 PM | Vaccine against prion disease, not for humans… yet
Prions, misfolded proteins that wreak havoc on the brain, may have finally met their match. Best known for things like mad cow disease and possibly alzheimer’s disease scientists have had no luck stopping prions, until now. Researchers say that a vaccination they have developed to fight a brain-based, wasting syndrome among deer and other animals […]

Goñi, F., Mathiason, C., Yim, L., Wong, K., Hayes-Klug, J., Nalls, A., Peyser, D., Estevez, V., Denkers, N., Xu, J. & Osborn, D. (2014). Mucosal immunization with an attenuated Salmonella vaccine partially protects white-tailed deer from chronic wasting disease, Vaccine, DOI: 10.1016/j.vaccine.2014.11.035

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8:21 PM | Vaccine against prion disease, not for humans… yet
Prions, misfolded proteins that wreak havoc on the brain, may have finally met their match. Best known for things like mad cow disease and possibly alzheimer’s disease scientists have had no luck stopping prions, until now. Researchers say that a vaccination they have developed to fight a brain-based, wasting syndrome among deer and other animals […]

Goñi, F., Mathiason, C., Yim, L., Wong, K., Hayes-Klug, J., Nalls, A., Peyser, D., Estevez, V., Denkers, N., Xu, J. & Osborn, D. (2014). Mucosal immunization with an attenuated Salmonella vaccine partially protects white-tailed deer from chronic wasting disease, Vaccine, DOI: 10.1016/j.vaccine.2014.11.035

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8:12 PM | What’s so healthy about skepticism?
He was known to the hospital as someone who would try to manipulate his caregivers. And I fell for it anyway. Frequently admitted for pain crises associated with a chronic illness, he spent most of... -- Read more on ScientificAmerican.com
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8:51 AM | Vitamin D for autism... a double-take?
Yes, I know. Another post on the 'day of rest' but I promise you that this will not become a habit. The reason: the paper by Feiyong Jia and colleagues [1] published in the premier journal Pediatrics. The authors describe a case report of a young child with autism who is observed to have shown improvement in some of the core symptoms of autism following supplementation with the [sunshine] vitamin/hormone of the hour: vitamin D. Further reporting on the paper can be seen […]

Feiyong Jia, Bing Wang, Ling Shan, Zhida Xu, Wouter G. Staal & Lin Du (2014). Core Symptoms of Autism Improved After Vitamin D Supplementation, Pediatrics, Other:

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1:11 AM | Cold Weather Myths: Healthcare Triage Is there a mother out...
Cold Weather Myths: Healthcare Triage Is there a mother out there who doesn’t warn their children that going out in the cold is going to make them sick? Have you heard that old chestnut about losing all of your body’s heat through your head? Do you think drinking alcohol will warm you up? All myths! We’ll discuss them on this week’s Healthcare Triage. For those of you who want to read more, go here: http://theincidentaleconomist.com/wordpress/?p=60130 By: Healthcare […]

December 20, 2014

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6:46 PM | Antidepressants and the effects on your unborn child
Think you know what causes depression? Well unfortunately scientists don’t have the exact answer, surprised? That’s not the only problem, there is an ever growing concern that we live in […]

Altieri SC, Yang H, O'Brien HJ, Redwine HM, Senturk D, Hensler JG & Andrews AM (2014). Perinatal vs. Genetic Programming of Serotonin States Associated with Anxiety., Neuropsychopharmacology, PMID: http://www.ncbi.nlm.nih.gov/pubmed/25523893

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6:46 PM | Antidepressants and the effects on your unborn child
Think you know what causes depression? Well unfortunately scientists don’t have the exact answer, surprised? That’s not the only problem, there is an ever growing concern that we live in […]

Altieri SC, Yang H, O'Brien HJ, Redwine HM, Senturk D, Hensler JG & Andrews AM (2014). Perinatal vs. Genetic Programming of Serotonin States Associated with Anxiety., Neuropsychopharmacology, PMID: http://www.ncbi.nlm.nih.gov/pubmed/25523893

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6:46 PM | Antidepressants and the effects on your unborn child
Think you know what causes depression? Well unfortunately scientists don’t have the exact answer, surprised? That’s not the only problem, there is an ever growing concern that we live in […]

Altieri SC, Yang H, O'Brien HJ, Redwine HM, Senturk D, Hensler JG & Andrews AM (2014). Perinatal vs. Genetic Programming of Serotonin States Associated with Anxiety., Neuropsychopharmacology, PMID: http://www.ncbi.nlm.nih.gov/pubmed/25523893

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6:46 PM | Antidepressants and the effects on your unborn child
Think you know what causes depression? Well unfortunately scientists don’t have the exact answer, surprised? That’s not the only problem, there is an ever growing concern that we live in […]

Altieri SC, Yang H, O'Brien HJ, Redwine HM, Senturk D, Hensler JG & Andrews AM (2014). Perinatal vs. Genetic Programming of Serotonin States Associated with Anxiety., Neuropsychopharmacology, PMID: http://www.ncbi.nlm.nih.gov/pubmed/25523893

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6:38 PM | 9 Tips To Save Your Life Sitting can be lethal - here’s...
9 Tips To Save Your Life Sitting can be lethal - here’s how to counteract it! By: AsapTHOUGHT.
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2:22 PM | AIDS Drug Also Offers Protection Against Malaria
Children with HIV/AIDS in Africa are at a higher-than-average risk for another deadly disease: malaria. But a team of Yale School of Public Health researchers has discovered that people taking […]
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2:21 PM | Knee meniscus fixed using revolutionary stem cell procedure
Researchers report on a revolutionary new procedure that uses 3-D printing and the body’s stem cells to regenerate knee meniscus, a tissue lining that acts as a natural cushion between […]
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9:00 AM | Joint hypermobility and links to psychiatry
"The relationship between JH/HDCT [joint hypermobility / heritable disorders of connective tissue] and mental disorders merits further attention in order to improve current knowledge and clarify a possible common etiology."There is nothing in the desert and no man needs nothing.That was the conclusion reached in the paper by Carolina Baeza-Velasco and colleagues [1] looking at the possibility of some interesting connections, outside of just physical presentation, when it […]

Baeza-Velasco C, Pailhez G, Bulbena A & Baghdadli A (2014). Joint hypermobility and the heritable disorders of connective tissue: clinical and empirical evidence of links with psychiatry., General hospital psychiatry, PMID: http://www.ncbi.nlm.nih.gov/pubmed/25459977

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December 19, 2014

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8:16 PM | Are You Sitting Too Much? by asapscience: Sitting too much can...
Are You Sitting Too Much? by asapscience: Sitting too much can literally be lethal. So here’s an excuse to take more breaks at work - just tell your boss “science said so!” There’s also some tips on how you can prevent these problems!
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7:58 PM | Lawsuit About Mayonnaise Dropped
In the old days, the battle between condiments was fought by Hellmann’s Mayonnaise and Miracle Whip. That was mostly a debate about taste rather than substance. Nowadays,…
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7:06 PM | Why “fat shaming” makes the problem worse
Thanks to the internet age we have lost touch with the fact that there is a human out there reading these words. Because of this, the golden rule –treat others […]

LOGEL, C., STINSON, D., GUNN, G., WOOD, J., HOLMES, J. & CAMERON, J. (2014). A little acceptance is good for your health: Interpersonal messages and weight change over time, Personal Relationships, 21 (4) 583-598. DOI: 10.1111/pere.12050

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7:06 PM | Why “fat shaming” makes the problem worse
Thanks to the internet age we have lost touch with the fact that there is a human out there reading these words. Because of this, the golden rule –treat others […]

LOGEL, C., STINSON, D., GUNN, G., WOOD, J., HOLMES, J. & CAMERON, J. (2014). A little acceptance is good for your health: Interpersonal messages and weight change over time, Personal Relationships, 21 (4) 583-598. DOI: 10.1111/pere.12050

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7:06 PM | Why “fat shaming” makes the problem worse
Thanks to the internet age we have lost touch with the fact that there is a human out there reading these words. Because of this, the golden rule –treat others […]

LOGEL, C., STINSON, D., GUNN, G., WOOD, J., HOLMES, J. & CAMERON, J. (2014). A little acceptance is good for your health: Interpersonal messages and weight change over time, Personal Relationships, 21 (4) 583-598. DOI: 10.1111/pere.12050

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