Posts

November 16, 2014

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8:27 PM | Beta-Blockers For Some Heart Failure Linked With Improved Survival
Up to 50 percent of patients with heart failure have normal or near-normal ejection fraction, termed heart failure with preserved ejection fraction (HFPEF). The risk of death in HFPEF may be as high as in heart failure with reduced ejection fraction (HFREF), but there is no proven therapy. Beta-blockers improve outcomes in HFREF and may be beneficial in HFPEF, but data are sparse and inconclusive, and beta-blockers are currently not indicated for treating HFPEF, according to background […]

November 06, 2014

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11:00 AM | Behind the scenes at an MRC Panel
We’ve looked at what it’s like to be a member of an MRC board, but what actually happens at a meeting? Katherine Nightingale sat in on part of a Panel […]

November 04, 2014

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3:52 PM | Anorexia Nervosa: Fasting and Starvation Brain Effects
Brain research in anorexia nervosa presents several challenges.Current knowledge of cognitive function in anorexia supports impairment in set shifting and global brain processing or central coherence.However, there are two issues that complicate understanding the underlying brain effects in anorexia nervosa.First, individuals with anorexia nervosa often have additional anxiety and mood disorders. It can be difficult to tease out the specific effects of anorexia nervosa from the effects of these […]

Pender, S., Gilbert, S. & Serpell, L. (2014). The Neuropsychology of Starvation: Set-Shifting and Central Coherence in a Fasted Nonclinical Sample, PLoS ONE, 9 (10) DOI: 10.1371/journal.pone.0110743

Billingsley-Marshall RL, Basso MR, Lund BC, Hernandez ER, Johnson CL, Drevets WC, McKee PA & Yates WR (2013). Executive function in eating disorders: the role of state anxiety., The International journal of eating disorders, 46 (4) 316-21. PMID: http://www.ncbi.nlm.nih.gov/pubmed/23354876

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3:52 PM | Anorexia Nervosa: Fasting and Starvation Brain Effects
Brain research in anorexia nervosa presents several challenges.Current knowledge of cognitive function in anorexia supports impairment in set shifting and global brain processing or central coherence.However, there are two issues that complicate understanding the underlying brain effects in anorexia nervosa.First, individuals with anorexia nervosa often have additional anxiety and mood disorders. It can be difficult to tease out the specific effects of anorexia nervosa from the effects of these […]

Pender, S., Gilbert, S. & Serpell, L. (2014). The Neuropsychology of Starvation: Set-Shifting and Central Coherence in a Fasted Nonclinical Sample, PLoS ONE, 9 (10) DOI: 10.1371/journal.pone.0110743

Billingsley-Marshall RL, Basso MR, Lund BC, Hernandez ER, Johnson CL, Drevets WC, McKee PA & Yates WR (2013). Executive function in eating disorders: the role of state anxiety., The International journal of eating disorders, 46 (4) 316-21. PMID: http://www.ncbi.nlm.nih.gov/pubmed/23354876

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10:43 AM | Bugs are us
There is growing recognition that the microorganisms which live in and on us ― our microbiome ― are crucial to our health. Anything that disrupts the delicate balance in which […]

November 03, 2014

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1:10 PM | The Age of Ebola: A Dallas Perspective
Working and living in the city where Ebola entered the United States caught me off guard. I wasn’t prepared to see downtown office workers don medical masks while walking the skywalks from one building to another. The occasional person pressing the elevator button with a tissue also surprised me. I caught myself worrying as I turned on the radio each morning. I hope there are no new cases. I heard reports that Air Canada airline attendants would wear gloves while attending to passengers. […]

October 30, 2014

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2:30 PM | The Risks And Rewards Of Two Popular Gastric Bypass Procedures
A recent study compared two of the most commonly performed bariatric surgery procedures. There are tradeoffs between the two surgical approaches in potential risks and benefits and so there has been an ongoing debate about which can achieve weight loss, with conflicting results in systematic reviews.  The two procedures were laparoscopic Roux-en-Y gastric bypass (RYGB) and adjustable gastric banding (AGB). The result was that RYGB resulted in much greater weight loss than AGB but had […]

October 27, 2014

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3:31 PM | E. Coli: Bacterial Diarrhea Vaccine Candidate Highly Efficacious
Each year, nearly 600,000 children die from severe, dehydrating diarrhea and millions more are hospitalized. Enterotoxigenic Escherichia coli (ETEC) may be the first enteric illness encountered by many infants, and it causes several hundred million cases of diarrhea each year, mainly in children. read more
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3:10 PM | Brain Imaging In Alcoholic Brain Thiamine Deficiency
Chronic consumption of large quantities of alcohol can produce severe deficiency of thiamine (vitamin B1).This can precipitate an acute brain failure known as Wernicke's encephalopathy. Wernicke's encephalopathy is characterized by sudden onset of mental status changes, eye muscle impairment and disturbed gait or ataxia.Other illnesses can also produce this level of severe thiamine deficiency. A partial list of these non-alcoholism causes for thiamine deficiency with encephalopathy […]

Manzo G, De Gennaro A, Cozzolino A, Serino A, Fenza G & Manto A (2014). MR imaging findings in alcoholic and nonalcoholic acute Wernicke's encephalopathy: a review., BioMed research international, 2014 503596. PMID: http://www.ncbi.nlm.nih.gov/pubmed/25050351

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