March 29, 2015

3:40 PM | Human Respiratory Tissue Model For Toxicity Of Inhaled Pollutants
A 3-dimensional model of human respiratory tissue has been shown to be effective for measuring the impact of chemicals, like those found in cigarette smoke or other aerosols, on the lung.  More effective lab-based tests are required to reduce the need for animal testing in assessing the toxicological effects of inhaled chemicals and safety of medicines. Traditional lab-based tests use cell lines that do not reflect normal lung structure and physiology, and in some cases have reduced, or […]

March 20, 2015

2:03 PM | AstraZeneca's Antibiotic Spin Off
I just came back from Boston and the annual meeting of BAARN – the Boston Area Antibiotic Resistance Network symposium held at the Broad Institute.  The meeting was interesting but the atmosphere was funereal. Many of those losing their jobs with the closure of Cubist’s research center in Lexington, Mass were there as were many whose jobs are threatened at AZ’s facility in Waltham, Mass. One major topic of discussion during the breaks was – where will all the […]

March 18, 2015

2:30 PM | Science doesn’t only need sprinters
At the moment, researchers have a certain number of years after their PhD to apply for MRC fellowships, after which point they’re ineligible. But is a ticking clock the best […]

March 17, 2015

2:02 AM | Glucose-Lowering Therapies To Treat Diabetes May Trigger Heart Failure
An examination of clinical trials covering more than 95,000 patients has found that glucose or sugar-lowering medications prescribed to patients with diabetes may pose an increased risk for the development of heart failure in these patients.Heart failure is a common occurrence for patients with type 2 diabetes and has a major impact on one's life expectancy and quality of life as well as representing a major driver of health care costs. Overall, the study found that for every one kilogram of […]

March 11, 2015

11:43 PM | Industry Clinical Trial Results More Likely To Be Disclosed Than Academic Ones
Academics have written a lot of articles claiming their competitors in the private sector selectively publish trials that favor their own interests don't care as much about transparency as academia, but is that really true? When it comes to investigational drugs, devices and biologic therapies, the data is available and it shows that industry was actually 3X more likely to comply with legal requirements than academic studies after disclosure was mandated. read more

March 04, 2015

5:52 PM | The “Right to Try” – Compassionate Use of Experimental Medicine, 5th Annual Cathy Shine Lecture
The “Right to Try” –  Compassionate Use of Experimental Medicine 5th Annual Cathy Shine Lecture Thursday, March 19, Noon – 1 p.m. Boston University Medical Campus Instructional Building Bakst Auditorium 72 East Concord Street, Boston, MA Free and open to … Continue reading →
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