Posts

March 05, 2015

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12:03 AM | Team accidentally finds key to DNA vaccination and genetic engineering
It might have been an accident, but like some lucky researchers accidents are a good thing. In this particular case, scientists have discovered a new way to manipulate how cells function, a finding that might help advance an experimental approach to improving public health: DNA vaccines, which could be more efficient, less expensive and easier […]

Gou, Y., Byun, H., Zook, A., B. Singh, G., Nash, A., Lozano, M. & Dudley, J. (2015). Retroviral vectors elevate coexpressed protein levels in trans through cap dependent translation through cap-dependent translation , Proceedings of the National Academy of Sciences, 201420477. DOI: 10.1073/pnas.1420477112

Citation
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12:03 AM | Team accidentally finds key to DNA vaccination and genetic engineering
It might have been an accident, but like some lucky researchers accidents are a good thing. In this particular case, scientists have discovered a new way to manipulate how cells function, a finding that might help advance an experimental approach to improving public health: DNA vaccines, which could be more efficient, less expensive and easier […]

Gou, Y., Byun, H., Zook, A., B. Singh, G., Nash, A., Lozano, M. & Dudley, J. (2015). Retroviral vectors elevate coexpressed protein levels in trans through cap dependent translation through cap-dependent translation , Proceedings of the National Academy of Sciences, 201420477. DOI: 10.1073/pnas.1420477112

Citation

March 04, 2015

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9:02 PM | A study of twins shows that autism is largely genetic
In the fight against misinformation about autism it seems science is starting to come out on top, finally. A new study hopes to add to the recent advancements made in the understanding of autism, which finds that a substantial genetic and moderate environmental influences were associated with risk of autism spectrum disorder (ASD) and broader autism […]

Colvert, E., Tick, B., McEwen, F., Stewart, C., Curran, S., Woodhouse, E., Gillan, N., Hallett, V., Lietz, S., Garnett, T. & Ronald, A. (2015). Heritability of Autism Spectrum Disorder in a UK Population-Based Twin Sample, JAMA Psychiatry, DOI: 10.1001/jamapsychiatry.2014.3028

Citation
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9:02 PM | A study of twins shows that autism is largely genetic
In the fight against misinformation about autism it seems science is starting to come out on top, finally. A new study hopes to add to the recent advancements made in the understanding of autism, which finds that a substantial genetic and moderate environmental influences were associated with risk of autism spectrum disorder (ASD) and broader autism […]

Colvert, E., Tick, B., McEwen, F., Stewart, C., Curran, S., Woodhouse, E., Gillan, N., Hallett, V., Lietz, S., Garnett, T. & Ronald, A. (2015). Heritability of Autism Spectrum Disorder in a UK Population-Based Twin Sample, JAMA Psychiatry, DOI: 10.1001/jamapsychiatry.2014.3028

Citation
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9:02 PM | A study of twins shows that autism is largely genetic
In the fight against misinformation about autism it seems science is starting to come out on top, finally. A new study hopes to add to the recent advancements made in the understanding of autism, which finds that a substantial genetic and moderate environmental influences were associated with risk of autism spectrum disorder (ASD) and broader autism […]

Colvert, E., Tick, B., McEwen, F., Stewart, C., Curran, S., Woodhouse, E., Gillan, N., Hallett, V., Lietz, S., Garnett, T. & Ronald, A. (2015). Heritability of Autism Spectrum Disorder in a UK Population-Based Twin Sample, JAMA Psychiatry, DOI: 10.1001/jamapsychiatry.2014.3028

Citation
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2:41 PM | Video Tip of the Week: Beacon, to locate genome variants of potential clinical significance
This week’s Video Tip of the Week follows on last week’s chatter about the Internet of DNA. As I mentioned then, the Beacon tool we touched on was going to get more coverage. So this week’s video is provided by the Beacon team, part of the larger Global Alliance for Genomics and Health project (GA4GH). […]

Nguyen N., Daniel R. Zerbino, Brian Raney, Dent Earl, Joel Armstrong, W. James Kent, David Haussler & Benedict Paten (2015). Building a Pan-Genome Reference for a Population, Journal of Computational Biology, 150107093755006. DOI: http://dx.doi.org/10.1089/cmb.2014.0146

Citation
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1:00 PM | Looking Sideways In The Mirror
Biology Concepts – platyhelminthes, asymmetry, bilateral symmetry, evolution, cephalization, natural selection, fish, lepidophagyWhat is the largest living structure on Earth? No, it’s not the 2200 acre Armillaria ostoyae fungus in Oregon that we talked about previously. That is the largest single organism, but there is something bigger. The Great Barrier Reef houses more species of coral than any other place on earth, more than 600 species call the reef home. You see how […]

Takeuchi, Y., Hori, M. & Oda, Y. (2012). Lateralized Kinematics of Predation Behavior in a Lake Tanganyika Scale-Eating Cichlid Fish, PLoS ONE, 7 (1) DOI: 10.1371/journal.pone.0029272

Lee, H., Kusche, H. & Meyer, A. (2012). Handed Foraging Behavior in Scale-Eating Cichlid Fish: Its Potential Role in Shaping Morphological Asymmetry, PLoS ONE, 7 (9) DOI: 10.1371/journal.pone.0044670

Kusche, H., Lee, H. & Meyer, A. (2012). Mouth asymmetry in the textbook example of scale-eating cichlid fish is not a discrete dimorphism after all, Proceedings of the Royal Society B: Biological Sciences, 279 (1748) 4715-4723. DOI: 10.1098/rspb.2012.2082

Takahashi, T. & Hori, M. (2008). Evidence of disassortative mating in a Tanganyikan cichlid fish and its role in the maintenance of intrapopulation dimorphism, Biology Letters, 4 (5) 497-499. DOI: 10.1098/rsbl.2008.0244

Hori, M., Ochi, H. & Kohda, M. (2007). Inheritance Pattern of Lateral Dimorphism in Two Cichlids (a Scale Eater, Perissodus microlepis, and an Herbivore, Neolamprologus moorii) in Lake Tanganyika, Zoological Science, 24 (5) 486-492. DOI: 10.2108/zsj.24.486

Citation
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1:00 PM | Looking Sideways In The Mirror
Biology Concepts – platyhelminthes, asymmetry, bilateral symmetry, evolution, cephalization, natural selection, fish, lepidophagyWhat is the largest living structure on Earth? No, it’s not the 2200 acre Armillaria ostoyae fungus in Oregon that we talked about previously. That is the largest single organism, but there is something bigger. The Great Barrier Reef houses more species of coral than any other place on earth, more than 600 species call the reef home. You see how […]

Takeuchi, Y., Hori, M. & Oda, Y. (2012). Lateralized Kinematics of Predation Behavior in a Lake Tanganyika Scale-Eating Cichlid Fish, PLoS ONE, 7 (1) DOI: 10.1371/journal.pone.0029272

Lee, H., Kusche, H. & Meyer, A. (2012). Handed Foraging Behavior in Scale-Eating Cichlid Fish: Its Potential Role in Shaping Morphological Asymmetry, PLoS ONE, 7 (9) DOI: 10.1371/journal.pone.0044670

Kusche, H., Lee, H. & Meyer, A. (2012). Mouth asymmetry in the textbook example of scale-eating cichlid fish is not a discrete dimorphism after all, Proceedings of the Royal Society B: Biological Sciences, 279 (1748) 4715-4723. DOI: 10.1098/rspb.2012.2082

Takahashi, T. & Hori, M. (2008). Evidence of disassortative mating in a Tanganyikan cichlid fish and its role in the maintenance of intrapopulation dimorphism, Biology Letters, 4 (5) 497-499. DOI: 10.1098/rsbl.2008.0244

Hori, M., Ochi, H. & Kohda, M. (2007). Inheritance Pattern of Lateral Dimorphism in Two Cichlids (a Scale Eater, Perissodus microlepis, and an Herbivore, Neolamprologus moorii) in Lake Tanganyika, Zoological Science, 24 (5) 486-492. DOI: 10.2108/zsj.24.486

Citation
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1:00 PM | Looking Sideways In The Mirror
Biology Concepts – platyhelminthes, asymmetry, bilateral symmetry, evolution, cephalization, natural selection, fish, lepidophagyWhat is the largest living structure on Earth? No, it’s not the 2200 acre Armillaria ostoyae fungus in Oregon that we talked about previously. That is the largest single organism, but there is something bigger. The Great Barrier Reef houses more species of coral than any other place on earth, more than 600 species call the reef home. You see how […]

Takeuchi, Y., Hori, M. & Oda, Y. (2012). Lateralized Kinematics of Predation Behavior in a Lake Tanganyika Scale-Eating Cichlid Fish, PLoS ONE, 7 (1) DOI: 10.1371/journal.pone.0029272

Lee, H., Kusche, H. & Meyer, A. (2012). Handed Foraging Behavior in Scale-Eating Cichlid Fish: Its Potential Role in Shaping Morphological Asymmetry, PLoS ONE, 7 (9) DOI: 10.1371/journal.pone.0044670

Kusche, H., Lee, H. & Meyer, A. (2012). Mouth asymmetry in the textbook example of scale-eating cichlid fish is not a discrete dimorphism after all, Proceedings of the Royal Society B: Biological Sciences, 279 (1748) 4715-4723. DOI: 10.1098/rspb.2012.2082

Takahashi, T. & Hori, M. (2008). Evidence of disassortative mating in a Tanganyikan cichlid fish and its role in the maintenance of intrapopulation dimorphism, Biology Letters, 4 (5) 497-499. DOI: 10.1098/rsbl.2008.0244

Hori, M., Ochi, H. & Kohda, M. (2007). Inheritance Pattern of Lateral Dimorphism in Two Cichlids (a Scale Eater, Perissodus microlepis, and an Herbivore, Neolamprologus moorii) in Lake Tanganyika, Zoological Science, 24 (5) 486-492. DOI: 10.2108/zsj.24.486

Citation
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1:00 PM | Looking Sideways In The Mirror
Biology Concepts – platyhelminthes, asymmetry, bilateral symmetry, evolution, cephalization, natural selection, fish, lepidophagyWhat is the largest living structure on Earth? No, it’s not the 2200 acre Armillaria ostoyae fungus in Oregon that we talked about previously. That is the largest single organism, but there is something bigger. The Great Barrier Reef houses more species of coral than any other place on earth, more than 600 species call the reef home. You see how […]

Takeuchi, Y., Hori, M. & Oda, Y. (2012). Lateralized Kinematics of Predation Behavior in a Lake Tanganyika Scale-Eating Cichlid Fish, PLoS ONE, 7 (1) DOI: 10.1371/journal.pone.0029272

Lee, H., Kusche, H. & Meyer, A. (2012). Handed Foraging Behavior in Scale-Eating Cichlid Fish: Its Potential Role in Shaping Morphological Asymmetry, PLoS ONE, 7 (9) DOI: 10.1371/journal.pone.0044670

Kusche, H., Lee, H. & Meyer, A. (2012). Mouth asymmetry in the textbook example of scale-eating cichlid fish is not a discrete dimorphism after all, Proceedings of the Royal Society B: Biological Sciences, 279 (1748) 4715-4723. DOI: 10.1098/rspb.2012.2082

Takahashi, T. & Hori, M. (2008). Evidence of disassortative mating in a Tanganyikan cichlid fish and its role in the maintenance of intrapopulation dimorphism, Biology Letters, 4 (5) 497-499. DOI: 10.1098/rsbl.2008.0244

Hori, M., Ochi, H. & Kohda, M. (2007). Inheritance Pattern of Lateral Dimorphism in Two Cichlids (a Scale Eater, Perissodus microlepis, and an Herbivore, Neolamprologus moorii) in Lake Tanganyika, Zoological Science, 24 (5) 486-492. DOI: 10.2108/zsj.24.486

Citation
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1:00 PM | Looking Sideways In The Mirror
Biology Concepts – platyhelminthes, asymmetry, bilateral symmetry, evolution, cephalization, natural selection, fish, lepidophagyWhat is the largest living structure on Earth? No, it’s not the 2200 acre Armillaria ostoyae fungus in Oregon that we talked about previously. That is the largest single organism, but there is something bigger. The Great Barrier Reef houses more species of coral than any other place on earth, more than 600 species call the reef home. You see how […]

Takeuchi, Y., Hori, M. & Oda, Y. (2012). Lateralized Kinematics of Predation Behavior in a Lake Tanganyika Scale-Eating Cichlid Fish, PLoS ONE, 7 (1) DOI: 10.1371/journal.pone.0029272

Lee, H., Kusche, H. & Meyer, A. (2012). Handed Foraging Behavior in Scale-Eating Cichlid Fish: Its Potential Role in Shaping Morphological Asymmetry, PLoS ONE, 7 (9) DOI: 10.1371/journal.pone.0044670

Kusche, H., Lee, H. & Meyer, A. (2012). Mouth asymmetry in the textbook example of scale-eating cichlid fish is not a discrete dimorphism after all, Proceedings of the Royal Society B: Biological Sciences, 279 (1748) 4715-4723. DOI: 10.1098/rspb.2012.2082

Takahashi, T. & Hori, M. (2008). Evidence of disassortative mating in a Tanganyikan cichlid fish and its role in the maintenance of intrapopulation dimorphism, Biology Letters, 4 (5) 497-499. DOI: 10.1098/rsbl.2008.0244

Hori, M., Ochi, H. & Kohda, M. (2007). Inheritance Pattern of Lateral Dimorphism in Two Cichlids (a Scale Eater, Perissodus microlepis, and an Herbivore, Neolamprologus moorii) in Lake Tanganyika, Zoological Science, 24 (5) 486-492. DOI: 10.2108/zsj.24.486

Citation
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9:41 AM | Asthma and autism: a spanner in the works?
As happens so many times in autism research, spanners are thrown in works. Take the paper from Ousseny Zerbo and colleagues [1] who concluded that: "children with autism have elevated prevalence of specific immune-related comorbidities". Nothing surprising about that finding based on the volumes of other research which seemed to have reached similar conclusions (see here).Then the spanner: "asthma was diagnosed significantly less often" in autism cases compared with asymptomatic controls. […]

Zerbo O, Leong A, Barcellos L, Bernal P, Fireman B & Croen LA (2015). Immune Mediated Conditions in Autism Spectrum Disorders., Brain, behavior, and immunity, PMID: http://www.ncbi.nlm.nih.gov/pubmed/25681541

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9:33 AM | Rules for the black birdwatcher | @GrrlScientist
Black bird watchers are rare birds themselves, and there are special rules that the black birder must observe to remain safe when out in the field chasing rare birds. “Any bird that’s black is my bird.”Are you a bird watcher, especially one who chases rare birds? If so, you most likely are white, fifty-five or older, and male. Female birders and young birders are unusual (in my experience), but the rarest birds of all are non-white birders. Continue reading...
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3:00 AM | Slug Slime Is A Liquid Crystal And It's Actually Pretty Incredible
You do not become a forest-floor-creeping mollusk on good looks alone; to crawl effectively, you need something with which to lubricate your wriggling, slimy, slithering self. Mucus, secreted in abundance from your entire body, is just the ticket. But slug slime is good for a lot more than whole-body lubrication.Read more...
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2:38 AM | For Hoff Yeti Crabs Food, Sex, and Birth Determine Living Space At Vents  
Within just a few short centimeters the temperature drops from 350˚C to -1.5˚C (692 to 29.3˚F). At 2.6 kilometers deep in the Antarctic Ocean lies the East Scotia Ridge (ESR) dotted with hydrothermal vents. Here, in this unique spot the world’s coldest ocean is in contact with one of the seafloor’s hottest environments. Life residing at hostile vents […]
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2:38 AM | For Hoff Yeti Crabs Food, Sex, and Birth Determine Living Space At Vents  
Within just a few short centimeters the temperature drops from 350˚C to -1.5˚C (692 to 29.3˚F). At 2.6 kilometers deep in the Antarctic Ocean lies the East Scotia Ridge (ESR) dotted with hydrothermal vents. Here, in this unique spot the world’s coldest ocean is in contact with one of the seafloor’s hottest environments. Life residing at hostile vents […]

March 03, 2015

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11:53 PM | Vivid New Seadragon Found Hiding in a Museum
Science has just introduced the first new seadragon species in 150 years, and the first new ichthyosaur species in 130 years. The coincidence illustrates the value of museum collections.
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10:40 PM | Humans Unconsciously Sniff Their Hands After Handshaking
Unlike dogs and other animals, humans — for the most part — don't sniff each other. Well, at least that's what we thought. A rather unsettling new study from the Weizmann Institute shows that practically all of us sniff our hands after handshaking — a possible sign of social chemosignaling behavior.Read more...
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10:13 PM | Is Cracking Your Knuckles Bad For You? Greg Foot answers whether...
Is Cracking Your Knuckles Bad For You? Greg Foot answers whether or not you can get arthritis from cracking your knuckles? Footnote 1 - http://www.medicalnewstoday.com/articles/259603.php Footnote 2 - deWeber , Olszewski and Ortolano, 2011. J Am Board Fam Med 24 (2), 169-174. Footnote 3 - DeWeber et al. 2011 Footnote 4 - http://www.jabfm.org/content/24/2/169 Footnote 5 - http://onlinelibrary.wiley.com/doi/10.1002/1529-0131%28199805%2941:5%3C949::AID-ART36%3E3.0.CO;2-3/abstract Footnote 6 - […]
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8:50 PM | From Drifter to Dynamo: The Story of Plankton
Most plankton are tiny drifters, wandering in a vast ocean. But where wind and currents converge they become part of a grander story… an explosion of vitality that affects all life on Earth, including our own.
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8:19 PM | Why Your Hair Will Turn Gray Why Does Hair Turn Gray with Old...
Why Your Hair Will Turn Gray Why Does Hair Turn Gray with Old Age? By: Life Noggin.
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7:41 PM | Early life stress may result in a serotonin deficit later
If you have experienced — or are experiencing — mood disorders like anxiety or depression, you know about SSRI’s and chances are they didn’t do much for you. In fact studies indicate that the majority of people with mood and anxiety disorders who receive Selective Serotonin Reuptake Inhibitors (SSRI’s) are not helped by these medications. Sadly, they […]

Coplan, J., Fulton, S., Reiner, W., Jackowski, A., Panthangi, V., Perera, T., Gorman, J., Huang, Y., Tang, C., Hof, P. & Kaffman, A. (2014). Elevated cerebrospinal fluid 5-hydroxyindoleacetic acid in macaques following early life stress and inverse association with hippocampal volume: preliminary implications for serotonin-related function in mood and anxiety disorders, Frontiers in Behavioral Neuroscience, 8 DOI: 10.3389/fnbeh.2014.00440

Coplan, J., Gopinath, S., Abdallah, C. & Berry, B. (2014). A Neurobiological Hypothesis of Treatment-Resistant Depression -- Mechanisms for Selective Serotonin Reuptake Inhibitor Non-Efficacy, Frontiers in Behavioral Neuroscience, 8 DOI: 10.3389/fnbeh.2014.00189

Citation
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7:41 PM | Early life stress may result in a serotonin deficit later
If you have experienced — or are experiencing — mood disorders like anxiety or depression, you know about SSRI’s and chances are they didn’t do much for you. In fact studies indicate that the majority of people with mood and anxiety disorders who receive Selective Serotonin Reuptake Inhibitors (SSRI’s) are not helped by these medications. Sadly, they […]

Coplan, J., Fulton, S., Reiner, W., Jackowski, A., Panthangi, V., Perera, T., Gorman, J., Huang, Y., Tang, C., Hof, P. & Kaffman, A. (2014). Elevated cerebrospinal fluid 5-hydroxyindoleacetic acid in macaques following early life stress and inverse association with hippocampal volume: preliminary implications for serotonin-related function in mood and anxiety disorders, Frontiers in Behavioral Neuroscience, 8 DOI: 10.3389/fnbeh.2014.00440

Coplan, J., Gopinath, S., Abdallah, C. & Berry, B. (2014). A Neurobiological Hypothesis of Treatment-Resistant Depression -- Mechanisms for Selective Serotonin Reuptake Inhibitor Non-Efficacy, Frontiers in Behavioral Neuroscience, 8 DOI: 10.3389/fnbeh.2014.00189

Citation
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7:41 PM | Early life stress may result in a serotonin deficit later
If you have experienced — or are experiencing — mood disorders like anxiety or depression, you know about SSRI’s and chances are they didn’t do much for you. In fact studies indicate that the majority of people with mood and anxiety disorders who receive Selective Serotonin Reuptake Inhibitors (SSRI’s) are not helped by these medications. Sadly, they […]

Coplan, J., Fulton, S., Reiner, W., Jackowski, A., Panthangi, V., Perera, T., Gorman, J., Huang, Y., Tang, C., Hof, P. & Kaffman, A. (2014). Elevated cerebrospinal fluid 5-hydroxyindoleacetic acid in macaques following early life stress and inverse association with hippocampal volume: preliminary implications for serotonin-related function in mood and anxiety disorders, Frontiers in Behavioral Neuroscience, 8 DOI: 10.3389/fnbeh.2014.00440

Coplan, J., Gopinath, S., Abdallah, C. & Berry, B. (2014). A Neurobiological Hypothesis of Treatment-Resistant Depression -- Mechanisms for Selective Serotonin Reuptake Inhibitor Non-Efficacy, Frontiers in Behavioral Neuroscience, 8 DOI: 10.3389/fnbeh.2014.00189

Citation
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7:41 PM | Early life stress may result in a serotonin deficit later
If you have experienced — or are experiencing — mood disorders like anxiety or depression, you know about SSRI’s and chances are they didn’t do much for you. In fact studies indicate that the majority of people with mood and anxiety disorders who receive Selective Serotonin Reuptake Inhibitors (SSRI’s) are not helped by these medications. Sadly, they […]

Coplan, J., Fulton, S., Reiner, W., Jackowski, A., Panthangi, V., Perera, T., Gorman, J., Huang, Y., Tang, C., Hof, P. & Kaffman, A. (2014). Elevated cerebrospinal fluid 5-hydroxyindoleacetic acid in macaques following early life stress and inverse association with hippocampal volume: preliminary implications for serotonin-related function in mood and anxiety disorders, Frontiers in Behavioral Neuroscience, 8 DOI: 10.3389/fnbeh.2014.00440

Coplan, J., Gopinath, S., Abdallah, C. & Berry, B. (2014). A Neurobiological Hypothesis of Treatment-Resistant Depression -- Mechanisms for Selective Serotonin Reuptake Inhibitor Non-Efficacy, Frontiers in Behavioral Neuroscience, 8 DOI: 10.3389/fnbeh.2014.00189

Citation
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7:41 PM | Early life stress may result in a serotonin deficit later
If you have experienced — or are experiencing — mood disorders like anxiety or depression, you know about SSRI’s and chances are they didn’t do much for you. In fact studies indicate that the majority of people with mood and anxiety disorders who receive Selective Serotonin Reuptake Inhibitors (SSRI’s) are not helped by these medications. Sadly, they […]

Coplan, J., Fulton, S., Reiner, W., Jackowski, A., Panthangi, V., Perera, T., Gorman, J., Huang, Y., Tang, C., Hof, P. & Kaffman, A. (2014). Elevated cerebrospinal fluid 5-hydroxyindoleacetic acid in macaques following early life stress and inverse association with hippocampal volume: preliminary implications for serotonin-related function in mood and anxiety disorders, Frontiers in Behavioral Neuroscience, 8 DOI: 10.3389/fnbeh.2014.00440

Coplan, J., Gopinath, S., Abdallah, C. & Berry, B. (2014). A Neurobiological Hypothesis of Treatment-Resistant Depression -- Mechanisms for Selective Serotonin Reuptake Inhibitor Non-Efficacy, Frontiers in Behavioral Neuroscience, 8 DOI: 10.3389/fnbeh.2014.00189

Citation
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7:41 PM | Early life stress may result in a serotonin deficit later
If you have experienced — or are experiencing — mood disorders like anxiety or depression, you know about SSRI’s and chances are they didn’t do much for you. In fact studies indicate that the majority of people with mood and anxiety disorders who receive Selective Serotonin Reuptake Inhibitors (SSRI’s) are not helped by these medications. Sadly, they […]

Coplan, J., Fulton, S., Reiner, W., Jackowski, A., Panthangi, V., Perera, T., Gorman, J., Huang, Y., Tang, C., Hof, P. & Kaffman, A. (2014). Elevated cerebrospinal fluid 5-hydroxyindoleacetic acid in macaques following early life stress and inverse association with hippocampal volume: preliminary implications for serotonin-related function in mood and anxiety disorders, Frontiers in Behavioral Neuroscience, 8 DOI: 10.3389/fnbeh.2014.00440

Coplan, J., Gopinath, S., Abdallah, C. & Berry, B. (2014). A Neurobiological Hypothesis of Treatment-Resistant Depression -- Mechanisms for Selective Serotonin Reuptake Inhibitor Non-Efficacy, Frontiers in Behavioral Neuroscience, 8 DOI: 10.3389/fnbeh.2014.00189

Citation
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7:41 PM | Early life stress may result in a serotonin deficit later
If you have experienced — or are experiencing — mood disorders like anxiety or depression, you know about SSRI’s and chances are they didn’t do much for you. In fact studies indicate that the majority of people with mood and anxiety disorders who receive Selective Serotonin Reuptake Inhibitors (SSRI’s) are not helped by these medications. Sadly, they […]

Coplan, J., Fulton, S., Reiner, W., Jackowski, A., Panthangi, V., Perera, T., Gorman, J., Huang, Y., Tang, C., Hof, P. & Kaffman, A. (2014). Elevated cerebrospinal fluid 5-hydroxyindoleacetic acid in macaques following early life stress and inverse association with hippocampal volume: preliminary implications for serotonin-related function in mood and anxiety disorders, Frontiers in Behavioral Neuroscience, 8 DOI: 10.3389/fnbeh.2014.00440

Coplan, J., Gopinath, S., Abdallah, C. & Berry, B. (2014). A Neurobiological Hypothesis of Treatment-Resistant Depression -- Mechanisms for Selective Serotonin Reuptake Inhibitor Non-Efficacy, Frontiers in Behavioral Neuroscience, 8 DOI: 10.3389/fnbeh.2014.00189

Citation
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7:41 PM | Early life stress may result in a serotonin deficit later
If you have experienced — or are experiencing — mood disorders like anxiety or depression, you know about SSRI’s and chances are they didn’t do much for you. In fact studies indicate that the majority of people with mood and anxiety disorders who receive Selective Serotonin Reuptake Inhibitors (SSRI’s) are not helped by these medications. Sadly, they […]

Coplan, J., Fulton, S., Reiner, W., Jackowski, A., Panthangi, V., Perera, T., Gorman, J., Huang, Y., Tang, C., Hof, P. & Kaffman, A. (2014). Elevated cerebrospinal fluid 5-hydroxyindoleacetic acid in macaques following early life stress and inverse association with hippocampal volume: preliminary implications for serotonin-related function in mood and anxiety disorders, Frontiers in Behavioral Neuroscience, 8 DOI: 10.3389/fnbeh.2014.00440

Coplan, J., Gopinath, S., Abdallah, C. & Berry, B. (2014). A Neurobiological Hypothesis of Treatment-Resistant Depression -- Mechanisms for Selective Serotonin Reuptake Inhibitor Non-Efficacy, Frontiers in Behavioral Neuroscience, 8 DOI: 10.3389/fnbeh.2014.00189

Citation
+
7:41 PM | Early life stress may result in a serotonin deficit later
If you have experienced — or are experiencing — mood disorders like anxiety or depression, you know about SSRI’s and chances are they didn’t do much for you. In fact studies indicate that the majority of people with mood and anxiety disorders who receive Selective Serotonin Reuptake Inhibitors (SSRI’s) are not helped by these medications. Sadly, they […]

Coplan, J., Fulton, S., Reiner, W., Jackowski, A., Panthangi, V., Perera, T., Gorman, J., Huang, Y., Tang, C., Hof, P. & Kaffman, A. (2014). Elevated cerebrospinal fluid 5-hydroxyindoleacetic acid in macaques following early life stress and inverse association with hippocampal volume: preliminary implications for serotonin-related function in mood and anxiety disorders, Frontiers in Behavioral Neuroscience, 8 DOI: 10.3389/fnbeh.2014.00440

Coplan, J., Gopinath, S., Abdallah, C. & Berry, B. (2014). A Neurobiological Hypothesis of Treatment-Resistant Depression -- Mechanisms for Selective Serotonin Reuptake Inhibitor Non-Efficacy, Frontiers in Behavioral Neuroscience, 8 DOI: 10.3389/fnbeh.2014.00189

Citation
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