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Posts

April 10, 2014

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5:02 AM | Resources For Blastocystis Epidemiology Research
 I often get questions related to Blastocystis epidemiology research, and many of these are 'how-to' questions.And as announced, I've chosen to dedicate a separate post listing some easy-to-use tools for subtyping Blastocystis from humans and animals.First, I want to guide your attention to the YouTube video that I made; it takes you through various important steps of subtyping and introduces you to the online database that can be used to call subtypes by BLASTing batches of fasta files - […]

Stensvold CR (2013). Comparison of sequencing (barcode region) and sequence-tagged-site PCR for Blastocystis subtyping., Journal of clinical microbiology, 51 (1) 190-4. PMID:

Alfellani MA, Taner-Mulla D, Jacob AS, Imeede CA, Yoshikawa H, Stensvold CR & Clark CG (2013). Genetic Diversity of Blastocystis in Livestock and Zoo Animals., Protist, 164 (4) 497-509. PMID:

Stensvold CR (2013). Blastocystis: Genetic diversity and molecular methods for diagnosis and epidemiology., Tropical parasitology, 3 (1) 26-34. PMID:

Alfellani MA, Stensvold CR, Vidal-Lapiedra A, Onuoha ES, Fagbenro-Beyioku AF & Clark CG (2013). Variable geographic distribution of Blastocystis subtypes and its potential implications., Acta tropica, 126 (1) 11-8. PMID:

Clark CG, van der Giezen M, Alfellani MA & Stensvold CR (2013). Recent developments in blastocystis research., Advances in parasitology, 82 1-32. PMID:

Stensvold CR, Ahmed UN, Andersen LO & Nielsen HV (2012). Development and Evaluation of a Genus-Specific, Probe-Based, Internal-Process-Controlled Real-Time PCR Assay for Sensitive and Specific Detection of Blastocystis spp., Journal of clinical microbiology, 50 (6) 1847-51. PMID:

Stensvold CR, Suresh GK, Tan KS, Thompson RC, Traub RJ, Viscogliosi E, Yoshikawa H & Clark CG (2007). Terminology for Blastocystis subtypes--a consensus., Trends in parasitology, 23 (3) 93-6. PMID:

Citation
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5:02 AM | Resources For Blastocystis Epidemiology Research
 I often get questions related to Blastocystis epidemiology research, and many of these are 'how-to' questions.And as announced, I've chosen to dedicate a separate post listing some easy-to-use tools for subtyping Blastocystis from humans and animals.First, I want to guide your attention to the YouTube video that I made; it takes you through various important steps of subtyping and introduces you to the online database that can be used to call subtypes by BLASTing batches of fasta files - […]

Stensvold CR (2013). Comparison of sequencing (barcode region) and sequence-tagged-site PCR for Blastocystis subtyping., Journal of clinical microbiology, 51 (1) 190-4. PMID:

Alfellani MA, Taner-Mulla D, Jacob AS, Imeede CA, Yoshikawa H, Stensvold CR & Clark CG (2013). Genetic Diversity of Blastocystis in Livestock and Zoo Animals., Protist, 164 (4) 497-509. PMID:

Stensvold CR (2013). Blastocystis: Genetic diversity and molecular methods for diagnosis and epidemiology., Tropical parasitology, 3 (1) 26-34. PMID:

Alfellani MA, Stensvold CR, Vidal-Lapiedra A, Onuoha ES, Fagbenro-Beyioku AF & Clark CG (2013). Variable geographic distribution of Blastocystis subtypes and its potential implications., Acta tropica, 126 (1) 11-8. PMID:

Clark CG, van der Giezen M, Alfellani MA & Stensvold CR (2013). Recent developments in blastocystis research., Advances in parasitology, 82 1-32. PMID:

Stensvold CR, Ahmed UN, Andersen LO & Nielsen HV (2012). Development and Evaluation of a Genus-Specific, Probe-Based, Internal-Process-Controlled Real-Time PCR Assay for Sensitive and Specific Detection of Blastocystis spp., Journal of clinical microbiology, 50 (6) 1847-51. PMID:

Stensvold CR, Suresh GK, Tan KS, Thompson RC, Traub RJ, Viscogliosi E, Yoshikawa H & Clark CG (2007). Terminology for Blastocystis subtypes--a consensus., Trends in parasitology, 23 (3) 93-6. PMID:

Citation

April 07, 2014

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4:58 PM | Neuronal memory
Francis Crick‘s astonishing hypothesis (1995) is that “You, your joys and your sorrows, your memories and your ambitions, your sense of personal identity and free will, are in fact no more than the behavior of a vast assembly of nerve cells and their associated molecules.” Actually, more than a hypothesis, this is the basis of […]

Larimer P. & Strowbridge B.W. (2009). Representing information in cell assemblies: persistent activity mediated by semilunar granule cells, Nature Neuroscience, 13 (2) 213-222. DOI:

Citation

April 04, 2014

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12:36 PM | Evidence indicates that VSELs from human adult tissues are multipotent
Rare, very small embryonic-like stem cells (VSELs) isolated from human adult tissues could provide a new source for developing regenerative therapies to repair complex tissues damaged by disease or trauma. The ability of these most-primitive, multipotent stem cells to differentiate into bone, neurons, connective tissue, and other cell types, and the proper criteria for identifying and isolating VSELs, are described in two new papers published in Stem Cells and Development, a peer-reviewed […]

Havens A.M., Sun H., Shiozawa Y., Jung Y., Wang J., Mishra A., Jiang Y., O'Neill D.W., Krebsbach P.H. & Rodgerson D.O. & (2014). Human and Murine Very Small Embryonic-Like Cells Represent Multipotent Tissue Progenitors, In Vitro and In Vivo, Stem Cells and Development, 23 (7) 689-701. DOI:

Suszynska M., Zuba-Surma E.K., Maj M., Mierzejewska K., Ratajczak J., Kucia M. & Ratajczak M.Z. (2014). The Proper Criteria for Identification and Sorting of Very Small Embryonic-Like Stem Cells, and Some Nomenclature Issues, Stem Cells and Development, 23 (7) 702-713. DOI:

Citation
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12:36 PM | Evidence indicates that VSELs from human adult tissues are multipotent
Rare, very small embryonic-like stem cells (VSELs) isolated from human adult tissues could provide a new source for developing regenerative therapies to repair complex tissues damaged by disease or trauma. The ability of these most-primitive, multipotent stem cells to differentiate into bone, neurons, connective tissue, and other cell types, and the proper criteria for identifying and isolating VSELs, are described in two new papers published in Stem Cells and Development, a peer-reviewed […]

Havens A.M., Sun H., Shiozawa Y., Jung Y., Wang J., Mishra A., Jiang Y., O'Neill D.W., Krebsbach P.H. & Rodgerson D.O. & (2014). Human and Murine Very Small Embryonic-Like Cells Represent Multipotent Tissue Progenitors, In Vitro and In Vivo, Stem Cells and Development, 23 (7) 689-701. DOI:

Suszynska M., Zuba-Surma E.K., Maj M., Mierzejewska K., Ratajczak J., Kucia M. & Ratajczak M.Z. (2014). The Proper Criteria for Identification and Sorting of Very Small Embryonic-Like Stem Cells, and Some Nomenclature Issues, Stem Cells and Development, 23 (7) 702-713. DOI:

Citation
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12:36 PM | Evidence indicates that VSELs from human adult tissues are multipotent
Rare, very small embryonic-like stem cells (VSELs) isolated from human adult tissues could provide a new source for developing regenerative therapies to repair complex tissues damaged by disease or trauma. The ability of these most-primitive, multipotent stem cells to differentiate into bone, neurons, connective tissue, and other cell types, and the proper criteria for identifying and isolating VSELs, are described in two new papers published in Stem Cells and Development, a peer-reviewed […]

Havens A.M., Sun H., Shiozawa Y., Jung Y., Wang J., Mishra A., Jiang Y., O'Neill D.W., Krebsbach P.H. & Rodgerson D.O. & (2014). Human and Murine Very Small Embryonic-Like Cells Represent Multipotent Tissue Progenitors, In Vitro and In Vivo, Stem Cells and Development, 23 (7) 689-701. DOI:

Suszynska M., Zuba-Surma E.K., Maj M., Mierzejewska K., Ratajczak J., Kucia M. & Ratajczak M.Z. (2014). The Proper Criteria for Identification and Sorting of Very Small Embryonic-Like Stem Cells, and Some Nomenclature Issues, Stem Cells and Development, 23 (7) 702-713. DOI:

Citation
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12:36 PM | Evidence indicates that VSELs from human adult tissues are multipotent
Rare, very small embryonic-like stem cells (VSELs) isolated from human adult tissues could provide a new source for developing regenerative therapies to repair complex tissues damaged by disease or trauma. The ability of these most-primitive, multipotent stem cells to differentiate into bone, neurons, connective tissue, and other cell types, and the proper criteria for identifying and isolating VSELs, are described in two new papers published in Stem Cells and Development, a peer-reviewed […]

Havens A.M., Sun H., Shiozawa Y., Jung Y., Wang J., Mishra A., Jiang Y., O'Neill D.W., Krebsbach P.H. & Rodgerson D.O. & (2014). Human and Murine Very Small Embryonic-Like Cells Represent Multipotent Tissue Progenitors, In Vitro and In Vivo, Stem Cells and Development, 23 (7) 689-701. DOI:

Suszynska M., Zuba-Surma E.K., Maj M., Mierzejewska K., Ratajczak J., Kucia M. & Ratajczak M.Z. (2014). The Proper Criteria for Identification and Sorting of Very Small Embryonic-Like Stem Cells, and Some Nomenclature Issues, Stem Cells and Development, 23 (7) 702-713. DOI:

Citation
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12:22 PM | New hope for the treatment of Amyotrophic lateral sclerosis
Kevin EgganHarvard stem cell researchers have discovered that a recently approved medication for epilepsy might be a meaningful treatment for patients with amyotrophic lateral sclerosis (ALS), also known as Lou Gehrig’s disease, a uniformly fatal neurodegenerative disorder. The researchers are now collaborating with Massachusetts General Hospital (MGH) to design an initial clinical trial testing the safety of the treatment in ALS patients.The investigators all caution that a great […]

Wainger B., Kiskinis E., Mellin C., Wiskow O., Han S.W., Sandoe J., Perez N., Williams L., Lee S. & Boulting G. & (2014). Intrinsic Membrane Hyperexcitability of Amyotrophic Lateral Sclerosis Patient-Derived Motor Neurons, Cell Reports, DOI:

Kiskinis E., Sandoe J., Williams L., Boulting G., Moccia R., Wainger B., Han S., Peng T., Thams S. & Mikkilineni S. & (2014). Pathways Disrupted in Human ALS Motor Neurons Identified through Genetic Correction of Mutant SOD1, Cell Stem Cell, DOI:

Citation
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12:22 PM | New hope for the treatment of Amyotrophic lateral sclerosis
Kevin EgganHarvard stem cell researchers have discovered that a recently approved medication for epilepsy might be a meaningful treatment for patients with amyotrophic lateral sclerosis (ALS), also known as Lou Gehrig’s disease, a uniformly fatal neurodegenerative disorder. The researchers are now collaborating with Massachusetts General Hospital (MGH) to design an initial clinical trial testing the safety of the treatment in ALS patients.The investigators all caution that a great […]

Wainger B., Kiskinis E., Mellin C., Wiskow O., Han S.W., Sandoe J., Perez N., Williams L., Lee S. & Boulting G. & (2014). Intrinsic Membrane Hyperexcitability of Amyotrophic Lateral Sclerosis Patient-Derived Motor Neurons, Cell Reports, DOI:

Kiskinis E., Sandoe J., Williams L., Boulting G., Moccia R., Wainger B., Han S., Peng T., Thams S. & Mikkilineni S. & (2014). Pathways Disrupted in Human ALS Motor Neurons Identified through Genetic Correction of Mutant SOD1, Cell Stem Cell, DOI:

Citation
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12:22 PM | New hope for the treatment of Amyotrophic lateral sclerosis
Kevin EgganHarvard stem cell researchers have discovered that a recently approved medication for epilepsy might be a meaningful treatment for patients with amyotrophic lateral sclerosis (ALS), also known as Lou Gehrig’s disease, a uniformly fatal neurodegenerative disorder. The researchers are now collaborating with Massachusetts General Hospital (MGH) to design an initial clinical trial testing the safety of the treatment in ALS patients.The investigators all caution that a great […]

Wainger B., Kiskinis E., Mellin C., Wiskow O., Han S.W., Sandoe J., Perez N., Williams L., Lee S. & Boulting G. & (2014). Intrinsic Membrane Hyperexcitability of Amyotrophic Lateral Sclerosis Patient-Derived Motor Neurons, Cell Reports, DOI:

Kiskinis E., Sandoe J., Williams L., Boulting G., Moccia R., Wainger B., Han S., Peng T., Thams S. & Mikkilineni S. & (2014). Pathways Disrupted in Human ALS Motor Neurons Identified through Genetic Correction of Mutant SOD1, Cell Stem Cell, DOI:

Citation
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12:22 PM | New hope for the treatment of Amyotrophic lateral sclerosis
Kevin EgganHarvard stem cell researchers have discovered that a recently approved medication for epilepsy might be a meaningful treatment for patients with amyotrophic lateral sclerosis (ALS), also known as Lou Gehrig’s disease, a uniformly fatal neurodegenerative disorder. The researchers are now collaborating with Massachusetts General Hospital (MGH) to design an initial clinical trial testing the safety of the treatment in ALS patients.The investigators all caution that a great […]

Wainger B., Kiskinis E., Mellin C., Wiskow O., Han S.W., Sandoe J., Perez N., Williams L., Lee S. & Boulting G. & (2014). Intrinsic Membrane Hyperexcitability of Amyotrophic Lateral Sclerosis Patient-Derived Motor Neurons, Cell Reports, DOI:

Kiskinis E., Sandoe J., Williams L., Boulting G., Moccia R., Wainger B., Han S., Peng T., Thams S. & Mikkilineni S. & (2014). Pathways Disrupted in Human ALS Motor Neurons Identified through Genetic Correction of Mutant SOD1, Cell Stem Cell, DOI:

Citation

March 28, 2014

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2:56 PM | Parenthood, Trial or Tribulation? Part 2
On New Year’s Day I became a parent, sparking my curiosity in the research on parenting and well-being and inspiring a four-part series on parenthood and happiness. This is the second post. Check out the first post here.Are parents happier than non-parents? Researchers have generally set about trying to answer this deceptively simple question in three ways:Are people with children happier than those without children?This is the most common approach to research on parenthood and […]

Callan, V. (1987). The Personal and Marital Adjustment of Mothers and of Voluntarily and Involuntarily Childless Wives, Journal of Marriage and the Family, 49 (4) 847. DOI:

Kahneman, D. (2004). A Survey Method for Characterizing Daily Life Experience: The Day Reconstruction Method, Science, 306 (5702) 1776-1780. DOI:

Lucas, R., Clark, A., Georgellis, Y. & Diener, E. (2003). Reexamining adaptation and the set point model of happiness: Reactions to changes in marital status., Journal of Personality and Social Psychology, 84 (3) 527-539. DOI:

Luhmann, M., Hofmann, W., Eid, M. & Lucas, R. (2012). Subjective well-being and adaptation to life events: A meta-analysis., Journal of Personality and Social Psychology, 102 (3) 592-615. DOI:

Nelson, S., Kushlev, K., English, T., Dunn, E. & Lyubomirsky, S. (2012). In Defense of Parenthood: Children Are Associated With More Joy Than Misery, Psychological Science, 24 (1) 3-10. DOI:

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March 19, 2014

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4:15 PM | Cigarette Smoking and Epigenetics: DNA Methylation Differences Between Ethnic Groups
Cigarette smoking leads to some of the most preventable causes of death and illness in the world. The Centers for Disease Control (CDC) in the United States has reported that there are approximately 440,000 deaths due to smoking each year, and an additional 49,000 deaths due to secondhand smoke.  Roughly 600 chemicals are found in ...The post Cigarette Smoking and Epigenetics: DNA Methylation Differences Between Ethnic Groups appeared first on EpiBeat.

Elliott HR, Tillin T, McArdle WL, Ho K, Duggirala A, Frayling TM, Davey Smith G, Hughes AD, Chaturvedi N & Relton CL & (2014). Differences in smoking associated DNA methylation patterns in South Asians and Europeans., Clinical epigenetics, 6 (1) 4. PMID:

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March 18, 2014

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10:09 PM | Sexual Dimorphism Found in Olfactory Processing Circuit
Chances are you have never heard of 14,16- androstadien-3-one (AND), but you have definitely smelled it if ever you’ve caught a whiff of a sweaty jogger who mistakenly forgot his deodorant.  AND is derived from testosterone and is found in male sweat, saliva, and semen. Its exposure has been shown to increase physiological arousal in […]

Ruta V., Datta S.R., Vasconcelos M.L., Freeland J., Looger L.L. & Axel R. (2010). A dimorphic pheromone circuit in Drosophila from sensory input to descending output, Nature, 468 (7324) 686-690. DOI:

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March 17, 2014

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2:13 PM | Uncovering the Life and Death of a Mummy
Deciphering how an ancient person lived and died is based heavily on the context of the buried body or mummy, including the soil around the gravesite, artifacts present in the grave and if nothing else, the location of the remains. What happens when there is no context? With skeletal remains or even bone fragments, which […]

Panzer S., Peschel O., Haas-Gebhard B., Bachmeier B.E., Pusch C.M. & Nerlich A.G. (2014). Reconstructing the Life of an Unknown (ca. 500 Years-Old South American Inca) Mummy - Multidisciplinary Study of a Peruvian Inca Mummy Suggests Severe Chagas Disease and Ritual Homicide., PloS one, PMID:

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