Posts

November 14, 2014

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1:00 PM | Breaking Research: Lithium may protect against Alzheimer’s and other aging-related diseases
As human life expectancy continues to increase at a steady rate in most countries worldwide, the prevalence of aging-related diseases is also increasing. One such example is Alzheimer’s disease (AD), the most common cause of dementia in the aging population. There is currently no cure for AD, and the only treatments that exist temporarily cover […]

Sofola-Adesakin O., Charalampos Rallis, Luke S. Tain, Ivana Bjedov, Iain Rogers, Li Li, Pedro Martinez, Mobina Khericha, Melissa Cabecinha & Jürg Bähler & (2014). Lithium suppresses Aβ pathology by inhibiting translation in an adult Drosophila model of Alzheimer's disease, Frontiers in Aging Neuroscience, 6 DOI: http://dx.doi.org/10.3389/fnagi.2014.00190

Forlenza O.V., Rodrigo Machado-Vieira, Breno S. Diniz & Wagner F. Gattaz (2012). Does Lithium Prevent Alzheimerʼs Disease?, Drugs , 29 (5) 335-342. DOI: http://dx.doi.org/10.2165/11599180-000000000-00000

Diniz B. & Forlenza (2013). Lithium and neuroprotection: translational evidence and implications for the treatment of neuropsychiatric disorders, Neuropsychiatric Disease and Treatment, 493. DOI: http://dx.doi.org/10.2147/ndt.s33086

Citation
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1:00 PM | Breaking Research: Lithium may protect against Alzheimer’s and other aging-related diseases
As human life expectancy continues to increase at a steady rate in most countries worldwide, the prevalence of aging-related diseases is also increasing. One such example is Alzheimer’s disease (AD), the most common cause of dementia in the aging population. There is currently no cure for AD, and the only treatments that exist temporarily cover […]

Sofola-Adesakin O., Charalampos Rallis, Luke S. Tain, Ivana Bjedov, Iain Rogers, Li Li, Pedro Martinez, Mobina Khericha, Melissa Cabecinha & Jürg Bähler & (2014). Lithium suppresses Aβ pathology by inhibiting translation in an adult Drosophila model of Alzheimer's disease, Frontiers in Aging Neuroscience, 6 DOI: http://dx.doi.org/10.3389/fnagi.2014.00190

Forlenza O.V., Rodrigo Machado-Vieira, Breno S. Diniz & Wagner F. Gattaz (2012). Does Lithium Prevent Alzheimerʼs Disease?, Drugs , 29 (5) 335-342. DOI: http://dx.doi.org/10.2165/11599180-000000000-00000

Diniz B. & Forlenza (2013). Lithium and neuroprotection: translational evidence and implications for the treatment of neuropsychiatric disorders, Neuropsychiatric Disease and Treatment, 493. DOI: http://dx.doi.org/10.2147/ndt.s33086

Citation
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1:00 PM | Breaking Research: Lithium may protect against Alzheimer’s and other aging-related diseases
As human life expectancy continues to increase at a steady rate in most countries worldwide, the prevalence of aging-related diseases is also increasing. One such example is Alzheimer’s disease (AD), the most common cause of dementia in the aging population. There is currently no cure for AD, and the only treatments that exist temporarily cover […]

Sofola-Adesakin O., Charalampos Rallis, Luke S. Tain, Ivana Bjedov, Iain Rogers, Li Li, Pedro Martinez, Mobina Khericha, Melissa Cabecinha & Jürg Bähler & (2014). Lithium suppresses Aβ pathology by inhibiting translation in an adult Drosophila model of Alzheimer's disease, Frontiers in Aging Neuroscience, 6 DOI: http://dx.doi.org/10.3389/fnagi.2014.00190

Forlenza O.V., Rodrigo Machado-Vieira, Breno S. Diniz & Wagner F. Gattaz (2012). Does Lithium Prevent Alzheimerʼs Disease?, Drugs , 29 (5) 335-342. DOI: http://dx.doi.org/10.2165/11599180-000000000-00000

Diniz B. & Forlenza (2013). Lithium and neuroprotection: translational evidence and implications for the treatment of neuropsychiatric disorders, Neuropsychiatric Disease and Treatment, 493. DOI: http://dx.doi.org/10.2147/ndt.s33086

Citation

November 07, 2014

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3:37 PM | Breaking Research: A method by which invading bacteria avoid detection could also be our key to defeating them
Have you ever wondered how our body recognizes when it’s being invaded by harmful bacteria? Nearly all forms of life—from single-celled organisms all the way to humans—have an “innate” immune system, which has evolved to recognize cellular components shared by broad groups of pathogens. One such example is peptidoglycan, a molecule found on the cell […]

Atilano M.L., Filipa Vaz, Maria João Catalão, Patricia Reed, Inês Ramos Grilo, Rita Gonçalves Sobral, Petros Ligoxygakis, Mariana Gomes Pinho & Sérgio Raposo Filipe (2014). Bacterial autolysins trim cell surface peptidoglycan to prevent detection by the Drosophila innate immune system, eLife, 3 DOI: http://dx.doi.org/10.7554/elife.02277

Citation
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3:37 PM | Breaking Research: A method by which invading bacteria avoid detection could also be our key to defeating them
Have you ever wondered how our body recognizes when it’s being invaded by harmful bacteria? Nearly all forms of life—from single-celled organisms all the way to humans—have an “innate” immune system, which has evolved to recognize cellular components shared by broad groups of pathogens. One such example is peptidoglycan, a molecule found on the cell […]

Atilano M.L., Filipa Vaz, Maria João Catalão, Patricia Reed, Inês Ramos Grilo, Rita Gonçalves Sobral, Petros Ligoxygakis, Mariana Gomes Pinho & Sérgio Raposo Filipe (2014). Bacterial autolysins trim cell surface peptidoglycan to prevent detection by the Drosophila innate immune system, eLife, 3 DOI: http://dx.doi.org/10.7554/elife.02277

Citation
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3:37 PM | Breaking Research: A method by which invading bacteria avoid detection could also be our key to defeating them
Have you ever wondered how our body recognizes when it’s being invaded by harmful bacteria? Nearly all forms of life—from single-celled organisms all the way to humans—have an “innate” immune system, which has evolved to recognize cellular components shared by broad groups of pathogens. One such example is peptidoglycan, a molecule found on the cell […]

Atilano M.L., Filipa Vaz, Maria João Catalão, Patricia Reed, Inês Ramos Grilo, Rita Gonçalves Sobral, Petros Ligoxygakis, Mariana Gomes Pinho & Sérgio Raposo Filipe (2014). Bacterial autolysins trim cell surface peptidoglycan to prevent detection by the Drosophila innate immune system, eLife, 3 DOI: http://dx.doi.org/10.7554/elife.02277

Citation

October 31, 2014

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3:48 PM | Halloween Special: The Drosophila Halloween Genes
In the movies, spooks and phantoms are often undead humans with unfinished business. But would you be afraid of a ghostly fruit fly? In 1995, fruit fly researchers Christiane Nüsslein-Volhard and Eric Wieschaus were awarded a Nobel Prize for their research on development. They were interested in understanding how a fertilized egg develops into a complex […]

Gilbert L.I. (2008). Drosophila is an inclusive model for human diseases, growth and development, Molecular and Cellular Endocrinology, 293 (1-2) 25-31. DOI: http://dx.doi.org/10.1016/j.mce.2008.02.009

Gilbert L.I. (2004). Halloween genes encode P450 enzymes that mediate steroid hormone biosynthesis in Drosophila melanogaster, Molecular and Cellular Endocrinology, 215 (1-2) 1-10. DOI: http://dx.doi.org/10.1016/j.mce.2003.11.003

Citation
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3:48 PM | Halloween Special: The Drosophila Halloween Genes
In the movies, spooks and phantoms are often undead humans with unfinished business. But would you be afraid of a ghostly fruit fly? In 1995, fruit fly researchers Christiane Nüsslein-Volhard and Eric Wieschaus were awarded a Nobel Prize for their research on development. They were interested in understanding how a fertilized egg develops into a complex […]

Gilbert L.I. (2008). Drosophila is an inclusive model for human diseases, growth and development, Molecular and Cellular Endocrinology, 293 (1-2) 25-31. DOI: http://dx.doi.org/10.1016/j.mce.2008.02.009

Gilbert L.I. (2004). Halloween genes encode P450 enzymes that mediate steroid hormone biosynthesis in Drosophila melanogaster, Molecular and Cellular Endocrinology, 215 (1-2) 1-10. DOI: http://dx.doi.org/10.1016/j.mce.2003.11.003

Citation
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3:48 PM | Halloween Special: The Drosophila Halloween Genes
In the movies, spooks and phantoms are often undead humans with unfinished business. But would you be afraid of a ghostly fruit fly? In 1995, fruit fly researchers Christiane Nüsslein-Volhard and Eric Wieschaus were awarded a Nobel Prize for their research on development. They were interested in understanding how a fertilized egg develops into a complex […]

Gilbert L.I. (2008). Drosophila is an inclusive model for human diseases, growth and development, Molecular and Cellular Endocrinology, 293 (1-2) 25-31. DOI: http://dx.doi.org/10.1016/j.mce.2008.02.009

Gilbert L.I. (2004). Halloween genes encode P450 enzymes that mediate steroid hormone biosynthesis in Drosophila melanogaster, Molecular and Cellular Endocrinology, 215 (1-2) 1-10. DOI: http://dx.doi.org/10.1016/j.mce.2003.11.003

Citation
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3:48 PM | Halloween Special: The Drosophila Halloween Genes
In the movies, spooks and phantoms are often undead humans with unfinished business. But would you be afraid of a ghostly fruit fly? In 1995, fruit fly researchers Christiane Nüsslein-Volhard and Eric Wieschaus were awarded a Nobel Prize for their research on development. They were interested in understanding how a fertilized egg develops into a complex […]

Gilbert L.I. (2008). Drosophila is an inclusive model for human diseases, growth and development, Molecular and Cellular Endocrinology, 293 (1-2) 25-31. DOI: http://dx.doi.org/10.1016/j.mce.2008.02.009

Gilbert L.I. (2004). Halloween genes encode P450 enzymes that mediate steroid hormone biosynthesis in Drosophila melanogaster, Molecular and Cellular Endocrinology, 215 (1-2) 1-10. DOI: http://dx.doi.org/10.1016/j.mce.2003.11.003

Citation
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3:48 PM | Halloween Special: The Drosophila Halloween Genes
In the movies, spooks and phantoms are often undead humans with unfinished business. But would you be afraid of a ghostly fruit fly? In 1995, fruit fly researchers Christiane Nüsslein-Volhard and Eric Wieschaus were awarded a Nobel Prize for their research on development. They were interested in understanding how a fertilized egg develops into a complex […]

Gilbert L.I. (2008). Drosophila is an inclusive model for human diseases, growth and development, Molecular and Cellular Endocrinology, 293 (1-2) 25-31. DOI: http://dx.doi.org/10.1016/j.mce.2008.02.009

Gilbert L.I. (2004). Halloween genes encode P450 enzymes that mediate steroid hormone biosynthesis in Drosophila melanogaster, Molecular and Cellular Endocrinology, 215 (1-2) 1-10. DOI: http://dx.doi.org/10.1016/j.mce.2003.11.003

Citation
+
3:48 PM | Halloween Special: The Drosophila Halloween Genes
In the movies, spooks and phantoms are often undead humans with unfinished business. But would you be afraid of a ghostly fruit fly? In 1995, fruit fly researchers Christiane Nüsslein-Volhard and Eric Wieschaus were awarded a Nobel Prize for their research on development. They were interested in understanding how a fertilized egg develops into a complex […]

Gilbert L.I. (2008). Drosophila is an inclusive model for human diseases, growth and development, Molecular and Cellular Endocrinology, 293 (1-2) 25-31. DOI: http://dx.doi.org/10.1016/j.mce.2008.02.009

Gilbert L.I. (2004). Halloween genes encode P450 enzymes that mediate steroid hormone biosynthesis in Drosophila melanogaster, Molecular and Cellular Endocrinology, 215 (1-2) 1-10. DOI: http://dx.doi.org/10.1016/j.mce.2003.11.003

Citation
+
3:48 PM | Halloween Special: The Drosophila Halloween Genes
In the movies, spooks and phantoms are often undead humans with unfinished business. But would you be afraid of a ghostly fruit fly? In 1995, fruit fly researchers Christiane Nüsslein-Volhard and Eric Wieschaus were awarded a Nobel Prize for their research on development. They were interested in understanding how a fertilized egg develops into a complex […]

Gilbert L.I. (2008). Drosophila is an inclusive model for human diseases, growth and development, Molecular and Cellular Endocrinology, 293 (1-2) 25-31. DOI: http://dx.doi.org/10.1016/j.mce.2008.02.009

Gilbert L.I. (2004). Halloween genes encode P450 enzymes that mediate steroid hormone biosynthesis in Drosophila melanogaster, Molecular and Cellular Endocrinology, 215 (1-2) 1-10. DOI: http://dx.doi.org/10.1016/j.mce.2003.11.003

Citation
+
3:48 PM | Halloween Special: The Drosophila Halloween Genes
In the movies, spooks and phantoms are often undead humans with unfinished business. But would you be afraid of a ghostly fruit fly? In 1995, fruit fly researchers Christiane Nüsslein-Volhard and Eric Wieschaus were awarded a Nobel Prize for their research on development. They were interested in understanding how a fertilized egg develops into a complex […]

Gilbert L.I. (2008). Drosophila is an inclusive model for human diseases, growth and development, Molecular and Cellular Endocrinology, 293 (1-2) 25-31. DOI: http://dx.doi.org/10.1016/j.mce.2008.02.009

Gilbert L.I. (2004). Halloween genes encode P450 enzymes that mediate steroid hormone biosynthesis in Drosophila melanogaster, Molecular and Cellular Endocrinology, 215 (1-2) 1-10. DOI: http://dx.doi.org/10.1016/j.mce.2003.11.003

Citation

October 24, 2014

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3:29 PM | Breaking Research: WIDE AWAKE is a newly identified gene that explains how we become sleepy at night
The body’s biological clock is responsible for keeping track of time and synchronizing behavior with the environment, so that you feel alert during daylight hours and sleepy at night. This biological clock (also called the circadian clock or circadian rhythms) consists of three major parts: The central pacemaker, which oscillates with a period of about […]

Liu S., Qili Liu, Masashi Tabuchi, Yong Yang, Melissa Fowler, Rajnish Bharadwaj, Julia Zhang, Joseph Bedont, Seth Blackshaw & Thomas E. Lloyd & (2014). WIDE AWAKE Mediates the Circadian Timing of Sleep Onset, Neuron, 82 (1) 151-166. DOI: http://dx.doi.org/10.1016/j.neuron.2014.01.040

Citation
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3:29 PM | Breaking Research: WIDE AWAKE is a newly identified gene that explains how we become sleepy at night
The body’s biological clock is responsible for keeping track of time and synchronizing behavior with the environment, so that you feel alert during daylight hours and sleepy at night. This biological clock (also called the circadian clock or circadian rhythms) consists of three major parts: The central pacemaker, which oscillates with a period of about […]

Liu S., Qili Liu, Masashi Tabuchi, Yong Yang, Melissa Fowler, Rajnish Bharadwaj, Julia Zhang, Joseph Bedont, Seth Blackshaw & Thomas E. Lloyd & (2014). WIDE AWAKE Mediates the Circadian Timing of Sleep Onset, Neuron, 82 (1) 151-166. DOI: http://dx.doi.org/10.1016/j.neuron.2014.01.040

Citation
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3:29 PM | Breaking Research: WIDE AWAKE is a newly identified gene that explains how we become sleepy at night
The body’s biological clock is responsible for keeping track of time and synchronizing behavior with the environment, so that you feel alert during daylight hours and sleepy at night. This biological clock (also called the circadian clock or circadian rhythms) consists of three major parts: The central pacemaker, which oscillates with a period of about […]

Liu S., Qili Liu, Masashi Tabuchi, Yong Yang, Melissa Fowler, Rajnish Bharadwaj, Julia Zhang, Joseph Bedont, Seth Blackshaw & Thomas E. Lloyd & (2014). WIDE AWAKE Mediates the Circadian Timing of Sleep Onset, Neuron, 82 (1) 151-166. DOI: http://dx.doi.org/10.1016/j.neuron.2014.01.040

Citation
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3:29 PM | Breaking Research: WIDE AWAKE is a newly identified gene that explains how we become sleepy at night
The body’s biological clock is responsible for keeping track of time and synchronizing behavior with the environment, so that you feel alert during daylight hours and sleepy at night. This biological clock (also called the circadian clock or circadian rhythms) consists of three major parts: The central pacemaker, which oscillates with a period of about […]

Liu S., Qili Liu, Masashi Tabuchi, Yong Yang, Melissa Fowler, Rajnish Bharadwaj, Julia Zhang, Joseph Bedont, Seth Blackshaw & Thomas E. Lloyd & (2014). WIDE AWAKE Mediates the Circadian Timing of Sleep Onset, Neuron, 82 (1) 151-166. DOI: http://dx.doi.org/10.1016/j.neuron.2014.01.040

Citation
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3:29 PM | Breaking Research: WIDE AWAKE is a newly identified gene that explains how we become sleepy at night
The body’s biological clock is responsible for keeping track of time and synchronizing behavior with the environment, so that you feel alert during daylight hours and sleepy at night. This biological clock (also called the circadian clock or circadian rhythms) consists of three major parts: The central pacemaker, which oscillates with a period of about […]

Liu S., Qili Liu, Masashi Tabuchi, Yong Yang, Melissa Fowler, Rajnish Bharadwaj, Julia Zhang, Joseph Bedont, Seth Blackshaw & Thomas E. Lloyd & (2014). WIDE AWAKE Mediates the Circadian Timing of Sleep Onset, Neuron, 82 (1) 151-166. DOI: http://dx.doi.org/10.1016/j.neuron.2014.01.040

Citation
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