Posts

February 23, 2015

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11:25 PM | Humans in the Wild.
This recent publication comes out of the lab of my graduate mentor. We actually brainstormed this experiment over libations on Bourbon Street in New Orleans. Sometimes, the best science comes to mind outside of the lab and when your guard is down. Anyways, Adam, DG, and a group of undergrads sorted through the power grid of […]

Stowie, A., Amacarelli, M., Crosier, C., Mymko, R. & Glass, J. (2014). Circadian analysis of large human populations: Inferences from the power grid, Chronobiology International, 1-7. DOI: 10.3109/07420528.2014.965316

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9:21 PM | Brain waves help memory formation
Our brains generate a constant hum of activity: As neurons fire, they produce brain waves that oscillate at different frequencies. Long thought to be merely a byproduct of neuron activity, recent studies suggest that these waves may play a critical role in communication between different parts of the brain. A new study adds to that […]

Brincat, S. & Miller, E. (2015). Frequency-specific hippocampal-prefrontal interactions during associative learning, Nature Neuroscience, DOI: 10.1038/nn.3954

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7:32 PM | Merging bacteria and solar technology to make fuel
Can living creatures be used to form part of a machine? While this might sound like something out of Doctor Who, the ever-trusty scientific barometer that is popular culture will tell us that this idea is perhaps not as horrific to us as it might first seem – from Robocop to hamster-powered school projects, the…

Torella JP, Gagliardi CJ, Chen JS, Bediako DK, Colón B, Way JC, Silver PA & Nocera DG (2015). Efficient solar-to-fuels production from a hybrid microbial-water-splitting catalyst system., Proceedings of the National Academy of Sciences of the United States of America, PMID: http://www.ncbi.nlm.nih.gov/pubmed/25675518

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3:06 PM | Effects of Iron Deficiency in Female Runners (A Guest Post)
By Ana Breit When people think of nutritional deficiencies, they probably picture women with goiters due to lack of iodine or other newsworthy examples. In reality, the most common nutritional deficiency in the United States is iron deficiency. Iron Deficiency (ID) is especially common in endurance athletes, especially female athletes. Start of 2013 Roy Griak Invitational Cross Country Meet at the University of Minnesota. Photo courtesy of Jennifer Larson.Iron is the metal in humans […]

Auersperger I, Škof B, Leskošek B, Knap B, Jerin A & Lainscak M (2013). Exercise-induced changes in iron status and hepcidin response in female runners., PloS one, 8 (3) PMID: http://www.ncbi.nlm.nih.gov/pubmed/23472137

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9:34 AM | Late, delayed and mis-diagnosis of autism
It's inevitable that with all the mountains of autism research published on a daily basis, certain themes will occur at certain times. My post today is reflective of one of those themes and how, on occasion, the autism diagnostic process does not run as smoothly as we would all like to think.I start this post with a link to an article discussing some forthcoming research to be published titled: 'The autistic pupils ‘traumatised’ by delayed diagnosis'. Describing the results of a […]

Davidovitch M, Levit-Binnun N, Golan D & Manning-Courtney P (2015). Late Diagnosis of Autism Spectrum Disorder After Initial Negative Assessment by a Multidisciplinary Team., Journal of developmental and behavioral pediatrics : JDBP, PMID: http://www.ncbi.nlm.nih.gov/pubmed/25651066

Aggarwal S & Angus B (2015). Misdiagnosis versus missed diagnosis: diagnosing autism spectrum disorder in adolescents., Australasian psychiatry : bulletin of Royal Australian and New Zealand College of Psychiatrists, PMID: http://www.ncbi.nlm.nih.gov/pubmed/25653302

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9:18 AM | The “Backfire Effect”: Correcting false beliefs about vaccines can be surprisingly counterproductive
Nearly half of the US population wrongly believes the flu vaccine can give you flu,but correcting this error has the opposite of the desired effectBy guest blogger Simon OxenhamAccording to a new study, 43 per cent of the US population wrongly believes that the flu vaccine can give you flu. In actual fact this is not the case – any adverse reaction, besides a temperature and aching muscles for a short time, is rare. It stands to reason that correcting this misconception would be a good […]

Nyhan, B. & Reifler, J. (2015). Does correcting myths about the flu vaccine work? An experimental evaluation of the effects of corrective information, Vaccine, 33 (3) 459-464. DOI: 10.1016/j.vaccine.2014.11.017

Brendan Nyhan, Jason Reifler, Sean Richey & Gary L. Freed (2014). Effective Messages in Vaccine Promotion: A Randomized Trial, PEDIATRICS, 133 (4) DOI: 10.1542/peds.2013-2365d

Lewandowsky, S., Ecker, U., Seifert, C., Schwarz, N. & Cook, J. (2012). Misinformation and Its Correction: Continued Influence and Successful Debiasing, Psychological Science in the Public Interest, 13 (3) 106-131. DOI: 10.1177/1529100612451018

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5:38 AM | Yes, autism is on the rise. Read this before blaming vaccines.
Waiting for the rain, © EEGBecause I work on HIV vaccine design, lately I've often been involved in debates concerning the safety of vaccines. I have the greatest respect for parents who struggle with disabilities of any kind, especially in children. I'm a parent too and can't even imagine what life is like when your child has a permanent disability. But I'm also a scientist, and I believe in the good cause of my work. My boss has been working day and night for thirty years on a vaccine […]

Nevison CD (2014). A comparison of temporal trends in United States autism prevalence to trends in suspected environmental factors., Environmental health : a global access science source, 13 73. PMID: http://www.ncbi.nlm.nih.gov/pubmed/25189402

Kalkbrenner AE, Windham GC, Serre ML, Akita Y, Wang X, Hoffman K, Thayer BP & Daniels JL (2015). Particulate matter exposure, prenatal and postnatal windows of susceptibility, and autism spectrum disorders., Epidemiology (Cambridge, Mass.), 26 (1) 30-42. PMID: http://www.ncbi.nlm.nih.gov/pubmed/25286049

Al-Farsi YM, Al-Sharbati MM, Waly MI, Al-Farsi OA, Al-Shafaee MA, Al-Khaduri MM, Trivedi MS & Deth RC (2012). Effect of suboptimal breast-feeding on occurrence of autism: a case-control study., Nutrition (Burbank, Los Angeles County, Calif.), 28 (7-8) 32. PMID: http://www.ncbi.nlm.nih.gov/pubmed/22541054

Le Belle JE, Sperry J, Ngo A, Ghochani Y, Laks DR, López-Aranda M, Silva AJ & Kornblum HI (2014). Maternal inflammation contributes to brain overgrowth and autism-associated behaviors through altered redox signaling in stem and progenitor cells., Stem cell reports, 3 (5) 725-34. PMID: http://www.ncbi.nlm.nih.gov/pubmed/25418720

Mulle, J., Sharp, W. & Cubells, J. (2013). The Gut Microbiome: A New Frontier in Autism Research, Current Psychiatry Reports, 15 (2) DOI: 10.1007/s11920-012-0337-0

Arrieta, M., Stiemsma, L., Amenyogbe, N., Brown, E. & Finlay, B. (2014). The Intestinal Microbiome in Early Life: Health and Disease, Frontiers in Immunology, 5 DOI: 10.3389/fimmu.2014.00427

Sandler RH, Finegold SM, Bolte ER, Buchanan CP, Maxwell AP, Väisänen ML, Nelson MN & Wexler HM (2000). Short-term benefit from oral vancomycin treatment of regressive-onset autism., Journal of child neurology, 15 (7) 429-35. PMID: http://www.ncbi.nlm.nih.gov/pubmed/10921511

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12:00 AM | New neurons in the adult brain help us adapt
The discovery that the human brain continues to produce new neurons in adulthood challenged a major dogma in the field of neuroscience, but the role of these neurons in behavior and cognition is still not clear. In a review article researchers synthesize the vast literature on this topic, reviewing environmental factors that influence the birth of […]

Opendak, M. & Gould, E. (2015). Adult neurogenesis: a substrate for experience-dependent change, Trends in Cognitive Sciences, DOI: 10.1016/j.tics.2015.01.001

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February 22, 2015

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4:11 PM | Of tree rings and rain: droughts predicted to worsen in southwestern United States
Droughts have intensified in already dry regions around the world, including in the Southwest United States and in Australia throughout the first decade of this century.  The severity of these droughts has been attributed to global warming and climate change, which … Continue reading →

Benjamin I. Cook, Toby R. Ault, Jason E. Smerdon (2015). Unprecedented 21st century drought risk in the American Southwest and Central Plains, Science Advances,

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4:55 AM | Pairwise games as a special case of public goods
Usually, when we are looking at public goods games, we consider an agent interacting with a group of n other agents. In our minds, we often imagine n to be large, or sometimes even take the limit as n goes to infinity. However, this isn’t the only limit that we should consider when we are […]

Bomze, I.M. (1983). Lotka-Volterra equation and replicator dynamics: A two-dimensional classification., Biological Cybernetics, 48 (3) 201-211. DOI: 10.1007/BF00318088

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February 21, 2015

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8:00 PM | Pandillas y Bandas Juveniles
El Fondo de las Naciones Unidas para la Infancia  (UNICEF, 2002) señala que en el mundo hay 1.200 millones de jóvenes de entre 10 y 19 años de edad, la mayor generación de adolescentes de la historia. Muchos de ellos llevan las riendas de un hogar, cuidan de hermanos pequeños y de progenitores enfermos, educan a sus compañeros sobre los desafíos de la vida y la mejor manera de protegerse frente a las enfermedades, entre ellas el SIDA, y […]

Jiménez Ornelas, R. (2005). La delincuencia juvenil: fenómeno de la sociedad actual, Papeles de Población, 11 (43) 215-261. Other:

Mateo, C. & González, C (1998). Bandas juveniles: violencia y moda, Revista Venezolana de Análisis de Coyuntura, 4 (1) 229-247.

Mejía Navarrete, J. (2001). Factores sociales que explican el pandillerismo juvenil, Sociología, 9 129-148.

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7:36 PM | Mental illness and ultradian rhythms
In the relatively new 24 hour, always on the go, digital lifestyle we live — might living a structured life with regularly established mealtimes and early bedtimes lead to a better life and perhaps even prevent the onset of mental illness? Well according to a new study, it might do just that, you could have a better quality […]

Blum, I., Zhu, L., Moquin, L., Kokoeva, M., Gratton, A., Giros, B. & Storch, K. (2014). A highly tunable dopaminergic oscillator generates ultradian rhythms of behavioral arousal, eLife, 3 DOI: 10.7554/eLife.05105

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10:39 AM | Coeliac disease: genes, autoimmunity, gut bacteria and bafflement?
Some things in life really do baffle me. When it comes to this blog, nothing seems to baffle me more than some of the talk about the triad that is autoimmunity, coeliac disease and gluten (see here for an example).My bafflement continued upon reading the papers by Emilsson and colleagues [1] and by Olivares and colleagues [2]. Respectively suggesting that: "spouses of individuals with celiac disease are at increased risk of non-celiac autoimmune disease" and "a specific disease-biased host […]

Emilsson L, Wijmenga C, Murray JA & Ludvigsson JF (2015). Autoimmune Disease in First-degree Relatives and Spouses of Individuals with Celiac Disease., Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association, PMID: http://www.ncbi.nlm.nih.gov/pubmed/25645875

Olivares M, Neef A, Castillejo G, Palma GD, Varea V, Capilla A, Palau F, Nova E, Marcos A, Polanco I & Ribes-Koninckx C (2014). The HLA-DQ2 genotype selects for early intestinal microbiota composition in infants at high risk of developing coeliac disease., Gut, PMID: http://www.ncbi.nlm.nih.gov/pubmed/24939571

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4:08 AM | Getting your tonsils removed: A (sometimes) cure for bedwetting
Kids who snore are more likely to wet the bed than kids who don’t. Strangely enough, the reason may be their too-big tonsils, which can cause the snoring and sleep apnea affecting 1 in 10 kids. In 2013, Michigan scientists … Continue reading →

Kovacevic L, Wolfe-Christensen C, Lu H, Toton M, Mirkovic J, Thottam PJ, Abdulhamid I, Madgy D & Lakshmanan Y (2014). Why does adenotonsillectomy not correct enuresis in all children with sleep disordered breathing?, The Journal of urology, 191 (5 Suppl) 1592-6. PMID: http://www.ncbi.nlm.nih.gov/pubmed/24679871

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February 20, 2015

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9:59 PM | Overriding muscles’ energy efficiency to burn more fat
What started as an evolutionary protection against starvation has become a biological “bad joke” for people who need to lose weight. The human body doesn’t distinguish between dieting and possible starvation, so when there is a decrease in calories consumed, human metabolism increases its energy efficiency and weight loss is resisted. In a new study […]

Koganti, S., Zhu, Z., Subbotina, E., Gao, Z., Sierra, A., Proenza, M., Yang, L., Alekseev, A., Hodgson-Zingman, D. & Zingman, L. & (2015). Disruption of KATP channel expression in skeletal muscle by targeted oligonucleotide delivery promotes activity-linked thermogenesis, Molecular Therapy, DOI: 10.1038/mt.2015.21

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8:43 AM | Behavioural sleep intervention for ADHD?
I was really quite interested to read about the study from Harriet Hiscock and colleagues [1] (open-access) suggesting that: "A brief behavioural sleep intervention modestly improves the severity of ADHD [attention deficit hyperactivity disorder] symptoms in a community sample of children with ADHD." I had heard that these results would be forthcoming based on the publication of the study trial protocol [2] a few years back, alongside the trial entry listed in the ISRCTN registry […]

Hiscock H, Sciberras E, Mensah F, Gerner B, Efron D, Khano S & Oberklaid F (2015). Impact of a behavioural sleep intervention on symptoms and sleep in children with attention deficit hyperactivity disorder, and parental mental health: randomised controlled trial., BMJ (Clinical research ed.), 350 PMID: http://www.ncbi.nlm.nih.gov/pubmed/25646809

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5:22 AM | One Brain Network for All Mental Illness
What do schizophrenia, bipolar disorder, major depression, addiction, obsessive compulsive disorder, and anxiety have in common? A loss of gray matter in the dorsal anterior cingulate cortex (dACC) and bilateral anterior insula, according to a recent review of the structural neuroimaging literature (Goodkind et al., 2015). These two brain regions are important for executive functions, the top-down cognitive processes that allow us to maintain goals and flexibly alter our behavior in response to […]

Goodkind, M., Eickhoff, S., Oathes, D., Jiang, Y., Chang, A., Jones-Hagata, L., Ortega, B., Zaiko, Y., Roach, E., Korgaonkar, M. & Grieve, S. (2015). Identification of a Common Neurobiological Substrate for Mental Illness, JAMA Psychiatry, DOI: 10.1001/jamapsychiatry.2014.2206

Kanai, R. & Rees, G. (2011). The structural basis of inter-individual differences in human behaviour and cognition, Nature Reviews Neuroscience, 12 (4) 231-242. DOI: 10.1038/nrn3000

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February 19, 2015

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8:31 PM | Predicting the effectiveness of cancer vaccines
Cancer vaccines, once they were science fiction and now they are designed to turn the body’s own immune system specifically against tumor cells. Particularly promising are vaccines that are directed against so-called neoantigens — which are proteins that have undergone a genetic mutation in tumor cells and, therefore, differ from their counterparts in healthy cells. […]

Bunse, L., Schumacher, T., Sahm, F., Pusch, S., Oezen, I., Rauschenbach, K., Gonzalez, M., Solecki, G., Osswald, M., Capper, D. & Wiestler, B. (2015). Proximity ligation assay evaluates IDH1R132H presentation in gliomas, Journal of Clinical Investigation, DOI: 10.1172/JCI77780

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12:06 PM | Threat of punishment makes us better judges of our own knowledge
People show better understanding oftheir own knowledge when threatenedwith large penalties for wrong answers. There are some walks of life where trying to be right as often as possible is not enough. Just as important is having insight into the likely accuracy of your own knowledge.Think of doctors and surgeons making diagnostic decisions. They can't be right all the time, and neither can they be completely certain over their judgments. What becomes important then, is that they have an […]

Arnold, M., Chisholm, L. & Prike, T. (2014). No pain no gain: The positive impact of punishment on the strategic regulation of accuracy, Memory, 1-8. DOI: 10.1080/09658211.2014.990982

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8:39 AM | Metal sensitisation and chronic fatigue syndrome?
I have to admit that I pondered longer than usual over whether I should talk about the paper by Vera Stejskal [1] (open-access here) and the idea that: "Patients with CFS [chronic fatigue syndrome] and fibromyalgia are frequently sensitized to metals found in the environment or used in dentistry and surgery."It was't that I doubted that metals - certain types present in the wrong place or wrong concentration - can affect physical and psychological health and wellbeing as per the […]

Stejskal V (2014). Metals as a common trigger of inflammation resulting in non-specific symptoms: diagnosis and treatment., The Israel Medical Association journal : IMAJ, 16 (12) 753-8. PMID: http://www.ncbi.nlm.nih.gov/pubmed/25630203

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February 18, 2015

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11:16 PM | The biofuel controversy
“Buses powered by soybeans.  Agricultural waste transformed into car fuel.  These possibilities have inspired governments around the world to include biofuels as a substantial part of their renewable energy standards, which mandate some percent of a country’s energy come from … Continue reading →

Horita, M., Kitamoto, H., Kawaide, T., Tachibana, Y. & Shinozaki, Y. (2015). On-farm solid state simultaneous saccharification and fermentation of whole crop forage rice in wrapped round bale for ethanol production, Biotechnology for Biofuels, 8 (1) DOI: 10.1186/s13068-014-0192-9

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8:13 PM | Scientists find anti-HIV agent and possible start for a vaccine
We may just have found a missing link in the fight towards an HIV vaccine. No, this is not an over-hyped headline, in a remarkable new advance against the virus that causes AIDS, scientists have announced the creation of a novel drug candidate that is so potent and universally effective, it might work as part of […]

Gardner, M., Kattenhorn, L., Kondur, H., von Schaewen, M., Dorfman, T., Chiang, J., Haworth, K., Decker, J., Alpert, M., Bailey, C. & Neale, E. (2015). AAV-expressed eCD4-Ig provides durable protection from multiple SHIV challenges, Nature, DOI: 10.1038/nature14264

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3:01 PM | Video Tip of the Week: RStudio as an interface for using R
Although typically we focus on databases and algorithms in use in bioinformatics and genomics, there are some other tools that support this work that are crucial as well. The statistical software and computing tools associated with R fall into this category. Increasingly RStudio is being adopted by folks in genomics, and although we talked about […]

Racine J.S. (2011). RStudio: A Platform-Independent IDE for R and Sweave, Journal of Applied Econometrics, 27 (1) 167-172. DOI: http://dx.doi.org/10.1002/jae.1278

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1:30 PM | What Do Young Children Learn From Pets?
Is a better understanding of biology something children can learn from dogs and cats?Young children are very interested in animals. One study even found children aged 11 – 40 months would prefer to look at an animal behind a glass screen (even if the animal is fast asleep) rather than play with a toy (LoBue et al 2013). Now researchers are asking whether this interest in animals means that children with a cat or dog know more about biology than those without.The study, by Megan Geerdts […]

LoBue, V., Bloom Pickard, M., Sherman, K., Axford, C. & DeLoache, J. (2013). Young children's interest in live animals, British Journal of Developmental Psychology, 31 (1) 57-69. DOI: 10.1111/j.2044-835X.2012.02078.x

Muldoon, J., Williams, J. & Lawrence, A. (2014). 'Mum cleaned it and I just played with it': Children's perceptions of their roles and responsibilities in the care of family pets, Childhood, DOI: 10.1177/0907568214524457

Geerdts, M., Van de Walle, G. & LoBue, V. (2015). Daily animal exposure and children’s biological concepts, Journal of Experimental Child Psychology, 130 132-146. DOI: 10.1016/j.jecp.2014.10.001

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12:30 PM | Space – It’ll Mess You Up
Biology concepts –  undulipodia, primary cilia, motile cilia, ependyma, spaceflight, pathology, osteopenia, radiation damage, osteoblast/osteoclast, osteocytes, No one wanted the elation of the moon visit to turn to disaster as a moon germ spread through-out the world and killed every living thing. So they moved the astronauts from splashdown to airstream. What a bummer that would have been to go all Andromeda Strain…. although it might have saved us from Watergate.Going into […]

Finetti, F., Paccani, S., Rosenbaum, J. & Baldari, C. (2011). Intraflagellar transport: a new player at the immune synapse, Trends in Immunology, 32 (4) 139-145. DOI: 10.1016/j.it.2011.02.001

Conroy, P., Saladino, C., Dantas, T., Lalor, P., Dockery, P. & Morrison, C. (2014). C-NAP1 and rootletin restrain DNA damage-induced centriole splitting and facilitate ciliogenesis, Cell Cycle, 11 (20) 3769-3778. DOI: 10.4161/cc.21986

Troshichev, O., Gorshkov, E., Shapovalov, S., Sokolovskii, V., Ivanov, V. & Vorobeitchikov, V. (2004). Variations of the gravitational field as a motive power for rhythmics of biochemical processes, Advances in Space Research, 34 (7) 1619-1624. DOI: 10.1016/j.asr.2004.02.013

Fitts, R., Trappe, S., Costill, D., Gallagher, P., Creer, A., Colloton, P., Peters, J., Romatowski, J., Bain, J. & Riley, D. & (2010). Prolonged space flight-induced alterations in the structure and function of human skeletal muscle fibres, The Journal of Physiology, 588 (18) 3567-3592. DOI: 10.1113/jphysiol.2010.188508

Rimmer J, Patel M, Agarwal K, Hogg C, Arshad Q & Harcourt J (2014). Peripheral Vestibular Dysfunction in Patients with Primary Ciliary Dyskinesia: Abnormal Otoconial Development?, Otology & neurotology : official publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology, PMID: http://www.ncbi.nlm.nih.gov/pubmed/25226371

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8:59 AM | Autism and the inter-pregnancy interval (again)
The paper from Maureen Durkin and colleagues [1] adds to something of a growing research evidence base suggesting that the temporal spacing between pregnancies / births - the inter-pregnancy interval (IPI) - may have something of an effect on the risk of receipt of a diagnosis of autism or autism spectrum disorder (ASD).We've been here before. In fact, a couple of times I've talked about the IPI in relation to autism risk (see here and see here) not including other, similar research findings in […]

Durkin MS, DuBois LA & Maenner MJ (2015). Inter-Pregnancy Intervals and the Risk of Autism Spectrum Disorder: Results of a Population-Based Study., Journal of autism and developmental disorders, PMID: http://www.ncbi.nlm.nih.gov/pubmed/25636677

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February 17, 2015

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7:26 PM | Shopping while hungry leads to more non-food purchases
Ever go shopping when you’re hungry and notice you walked out with a lot more than you were expecting to buy? While most people know that when you are hungry, you typically will buy more food (as illustrated by The Oatmeal above), new research shows that there is a clear link between hunger and buying […]

Alison Jing Xu, Norbert Schwarz & Robert S. Wyer, Jr (2015). Hunger promotes acquisition of nonfood objects, Proceedings of the National Academy of Sciences of the United States of America, Other:

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8:57 AM | Congenital rubella, autism and remote stroke
Case reports. I know they rank pretty low in the order of what counts as objective scientific evidence [1] despite their often interesting findings. That being said, when it comes to a diagnosis like autism, with all its associated heterogeneity and elevated risk of various comorbidity probably better encapsulated in a more 'plural autisms' understanding, case reports can offer something of an important view into the many and varied ways in which someone might arrive on the autism spectrum and […]

George J Hutton, J. (2014). Congenital Rubella with Autism and Evidence of a Remote Stroke, Journal of Vaccines & Vaccination, 05 (06) DOI: 10.4172/2157-7560.1000258

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February 16, 2015

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11:00 PM | Why low-carb or fasting diets are good for your health
While most research regarding fat loss focuses on the risks of being overweight, a new study shows that fasting, low-carb diets, or high-intensity exercise have specific health benefits. Specifically, researchers have found that a compound produced by the body when dieting or fasting can block a part of the immune system involved in several inflammatory […]

Youm, Y., Nguyen, K., Grant, R., Goldberg, E., Bodogai, M., Kim, D., D'Agostino, D., Planavsky, N., Lupfer, C., Kanneganti, T. & Kang, S. (2015). The ketone metabolite β-hydroxybutyrate blocks NLRP3 inflammasome–mediated inflammatory disease, Nature Medicine, DOI: 10.1038/nm.3804

Coll, R., Robertson, A., Chae, J., Higgins, S., Muñoz-Planillo, R., Inserra, M., Vetter, I., Dungan, L., Monks, B., Stutz, A. & Croker, D. (2015). A small-molecule inhibitor of the NLRP3 inflammasome for the treatment of inflammatory diseases, Nature Medicine, DOI: 10.1038/nm.3806

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8:54 PM | Cigarette Smoking Leads to Thinning of the Brain’s Cortex
Cigarette smoking is associated with cognitive decline and dementia, but the extent of the association between smoking and structural brain changes remains unclear. According to recent study published by Karama et.al., in Molecular Psychiatry, “long-term smoking could cause thinning of the outer layer of the brain involved in critical cognitive functions such as memory and language.” Although the cortex grows thinner with normal ageing, the study found that smoking appears to […]

Karama, S., Ducharme, S., Corley, J., Chouinard-Decorte, F., Starr, J., Wardlaw, J., Bastin, M. & Deary, I. (2015). Cigarette smoking and thinning of the brain’s cortex, Molecular Psychiatry, DOI: 10.1038/mp.2014.187

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