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Posts

April 07, 2014

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6:53 PM | Researchers Use Sun to Make Solar Energy Materials
Researchers at Oregon State University have discovered a way to tap the sun not only as a source of power, but also to directly produce the solar energy materials that make this possible. Read more »

Kim, K., Oleksak, R., Pan, C., Knapp, M., Kreider, P., Herman, G. & Chang, C. (2014). Continuous synthesis of colloidal chalcopyrite copper indium diselenide nanocrystal inks, RSC Advances, 4 (32) 16418. DOI:

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6:04 PM | Speciation in Reverse
I don’t usually advertise my Accumulating Glitches posts on here, but I decided to make an exception for today’s post. …Continue reading →

Kleindorfer S, O'Connor JA, Dudaniec RY, Myers SA, Robertson J & Sulloway FJ (2014). Species collapse via hybridization in Darwin's tree finches., The American naturalist, 183 (3) 325-41. PMID:

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5:58 PM | New Electrolyte to Enable Fast-Charging Li-Ion Batteries
Scientists in Japan have developed an innovative electrolyte that may be the key to the next great breakthrough in advanced lithium-ion batteries. Read more »

Yamada, Y., Furukawa, K., Sodeyama, K., Kikuchi, K., Yaegashi, M., Tateyama, Y. & Yamada, A. (2014). Unusual Stability of Acetonitrile-Based Superconcentrated Electrolytes for Fast-Charging Lithium-Ion Batteries, Journal of the American Chemical Society, 136 (13) 5039-5046. DOI:

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4:58 PM | Neuronal memory
Francis Crick‘s astonishing hypothesis (1995) is that “You, your joys and your sorrows, your memories and your ambitions, your sense of personal identity and free will, are in fact no more than the behavior of a vast assembly of nerve cells and their associated molecules.” Actually, more than a hypothesis, this is the basis of […]

Larimer P. & Strowbridge B.W. (2009). Representing information in cell assemblies: persistent activity mediated by semilunar granule cells, Nature Neuroscience, 13 (2) 213-222. DOI:

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4:41 PM | Multi-Gene Engineering Could Boost Seed Oil Content in Oilseed Crops
A team of researchers from Rothamsted Research, one of the oldest agricultural research institutions in the world, have published the first study to target multiple genes that control a series of important steps in the pathway for seed oil production (see footnote). Read more »

van Erp, H., Kelly, A., Menard, G. & Eastmond, P. (2014). Multi-gene engineering of triacylglycerol metabolism boosts seed oil content in Arabidopsis, PLANT PHYSIOLOGY, DOI:

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3:02 PM | Illacme plenipes - World's leggiest creature
Illacme plenipesCredit: Paul Marek et. al.Kingdom: AnimaliaPhylum: ArthropodaClass: Diplopoda Order: Siphonophorida Family: SiphonorhinidaeGenus: IllacmeSpecies: Illacme plenipesConservation Status: Not officially assessed, possibly threatened by extinctionCommon Name: NoneDespite their name, we have yet to discover a millipede species that has one thousand legs. However, the rare Illacme plenipes comes very close to this number, with one recorded specimen having 750 legs.The species has […]

Marek PE & Bond JE (2006). Biodiversity hotspots: rediscovery of the world's leggiest animal., Nature, 441 (7094) 707. PMID:

Marek, P., Shear, W. & Bond, J. (2012). A redescription of the leggiest animal, the millipede Illacme plenipes, with notes on its natural history and biogeography (Diplopoda, Siphonophorida, Siphonorhinidae), ZooKeys, 241 77-112. DOI:

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12:53 PM | Hummingbirds: still evolving endless forms most wonderful | @GrrlScientist
A new study finds that the rising Andes is tied to the rapid speciation of hummingbirds. This study also predicts that hummingbirds will evolve twice as many species as what we see today."There is grandeur in this view of life, with its several powers, having been originally breathed into a few forms or into one; and that, whilst this planet has gone cycling on according to the fixed law of gravity, from so simple a beginning endless forms most beautiful and most wonderful have been, and are […]

McGuire J.A., Witt C.C., Remsen, Jr. J.V., Corl A., Rabosky D.L., Altshuler D.L. & Dudley R. (2014). Molecular Phylogenetics and the Diversification of Hummingbirds, Current Biology, DOI:

Hoorn C., Wesselingh F.P., ter Steege H., Bermudez M.A., Mora A., Sevink J., Sanmartin I., Sanchez-Meseguer A., Anderson C.L. & Figueiredo J.P. & (2010). Amazonia Through Time: Andean Uplift, Climate Change, Landscape Evolution, and Biodiversity, Science, 330 (6006) 927-931. DOI:

Mayr G. (2004). Old World Fossil Record of Modern-Type Hummingbirds, Science, 304 (5672) 861-864. DOI:

Doorn G.S.V., Noest A.J. & Hogeweg P. (1998). Sympatric speciation and extinction driven by environment dependent sexual selection, Proceedings of the Royal Society B: Biological Sciences, 265 (1408) 1915-1919. DOI:

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12:35 PM | Usher Syndrome and Cochlear Implants – Hearing Sound for the First Time
There aren’t many of us who won’t have read the heart-warming story about Joanne Milne, an Usher syndrome sufferer who, after being profoundly deaf her whole life, was able to […]

Cosgrove, D. & Zallocchi, M. (2014). Usher protein functions in hair cells and photoreceptors, The International Journal of Biochemistry & Cell Biology, 46 80-89. DOI:

Loundon, N., Marlin, S., Busquet, D., Denoyelle, F., Roger, G., Renaud, F. & Garabedian, E. (2003). Usher Syndrome and Cochlear Implantation, Otology & Neurotology, 24 (2) 216-221. DOI:

Petit C (2001). Usher syndrome: from genetics to pathogenesis, Annu Rev Genomics Hum Genet,

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11:03 AM | “7 a Day” is the new “5 a Day”: stop being so serious about veg!
You probably saw the news last week that you should “Forget five a day: You need SEVEN portions a day for a long life”. Yes you read that correctly, research now tells us that should eat seven – or possibly even ten – portions of fruit and veg every day to help keep disease at … Continue reading →

WHO (2009). Diet, Nutrition and the Prevention of Chronic Diseases* A Report of the WHO Study Group on Diet, Nutrition and Prevention of Noncommunicable Diseases**, Nutrition Reviews, 49 (10) 291-301. DOI:

Oyebode, O., Gordon-Dseagu, V., Walker, A. & Mindell, J. (2014). Fruit and vegetable consumption and all-cause, cancer and CVD mortality: analysis of Health Survey for England data, Journal of Epidemiology & Community Health, DOI:

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3:45 AM | Kleene’s variant of the Church-Turing thesis
In 1936, Alonzo Church, Alan Turing, and Emil Post each published independent papers on the Entscheidungsproblem and introducing the lambda calculus, Turing machines, and Post-Turing machines as mathematical models of computation. A myriad of other models followed, many of them taking seemingly unrelated approaches to the computable: algebraic, combinatorial, linguistic, logical, mechanistic, etc. Of course, […]

Dershowitz, N. & Gurevich, Y. (2008). A natural axiomatization of computability and proof of Church's Thesis, Bulletin of Symbolic Logic, 14 (3) 299-350. DOI:

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April 06, 2014

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4:41 PM | Look! A Morsel of Good Vaccination News
It’s been a bad few weeks for vaccination. Whooping cough continues to make a comeback; it was revealed that some New York City schools have third-world vaccination rates; and a study led by Brendan Nyhan found that four different interventions were unable to shift vaccination intentions. So it may come as a surprise that a […]

Cox, D., Sturm, L. & Cox, A. (2014). Effectiveness of Asking Anticipated Regret in Increasing HPV Vaccination Intention in Mothers., Health Psychology, DOI:

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2:37 PM | Can 7-a-day save your life?
On the 1st of April I heard over my morning cup of coffee that new research suggests that the staple 5-a-day which has been ingrained into our idea of health since […]

Oyebode O, Gordon-Dseagu V, Walker A & Mindell JS (2014). Fruit and vegetable consumption and all-cause, cancer and CVD mortality: analysis of Health Survey for England data., Journal of epidemiology and community health, PMID:

Lock K, Pomerleau J, Causer L, Altmann DR & McKee M (2005). The global burden of disease attributable to low consumption of fruit and vegetables: implications for the global strategy on diet., Bulletin of the World Health Organization, 83 (2) 100-8. PMID:

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12:00 PM | Enceladus and Water – What This Means for Life
Scientists at the California Institute of Technology recently announced that they have evidence of water on Saturn’s tiny moon Enceladus. And not only is there water, it is probably liquid water. How can this be possible on an object that is almost 900 million miles away from the Sun (about 10 times the Earth-Sun distance) and has a temperature of – 201 degrees Celsius (-330 … Read More → The post Enceladus and Water – What This Means for Life appeared first on […]

Iess L., Stevenson D.J., Parisi M., Hemingway D., Jacobson R.A., Lunine J.I., Nimmo F., Armstrong J.W., Asmar S.W. & Ducci M. & (2014). The Gravity Field and Interior Structure of Enceladus, Science, 344 (6179) 78-80. DOI:

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9:09 AM | The Himalaya: mountains made from mountains
Good building stones get reused. Sometimes the only traces of very old buildings are their stones, built into more modern ones. It’s the same with rocks and mountain belts. Stone that now forms parts of the Himalaya was once part … Continue reading →

Mottram C.M., Argles T.W., Harris N.B.W., Parrish R.R., Horstwood M.S.A., Warren C.J. & Gupta S. (2014). Tectonic interleaving along the Main Central Thrust, Sikkim Himalaya, Journal of the Geological Society, 171 (2) 255-268. DOI:

Argles T.W., Prince C.I., Foster G.L. & Vance D. (1999). New garnets for old? Cautionary tales from young mountain belts, Earth and Planetary Science Letters, 172 (3-4) 301-309. DOI:

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6:47 AM | Vitamin D deficiency and more and risk of ADHD
"Vitamin D – could it stop 'modern’ diseases?" was one of the headlines I read quite recently as more pressure is being applied on the sunshine vitamin to perform when it comes to our health and welbeing. Indeed, not so long ago I posted an entry updating where we're at when it comes to the 'sunshine' vitamin D and the autism spectrum conditions. The conclusion buried in that post was that whilst there is some interesting work potentially linking vitamin D and autism, there is still […]

Bener A & Kamal M (2013). Predict attention deficit hyperactivity disorder? Evidence -based medicine., Global journal of health science, 6 (2) 47-57. PMID:

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6:45 AM | Review on PCR based diagnostic approaches for detection of intestinal parasites
My colleague Jaco Verweij – a pioneer in terms of developing and applying real-time PCR diagnostics in clinical parasitology – and I have put together a review in the journal Clinical Microbiology Reviews with the title: Molecular Testing for Clinical Diagnosis and Epidemiological Investigations of Intestinal Parasitic Infections It’s available form the journal’s website here. […]

Verweij JJ & Stensvold CR (2014). Molecular testing for clinical diagnosis and epidemiological investigations of intestinal parasitic infections., Clinical microbiology reviews, 27 (2) 371-418. PMID:

Lee MY, Cho EJ, Lee JH, Han SH & Park YS (2011). A ten-year survey of Giardia cysts in drinking water supplies of Seoul, the Republic of Korea., The Korean journal of parasitology, 49 (1) 9-15. PMID:

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4:21 AM | How does BT work?
Life, at it’s most basic level is really just a series of chemical reactions. Biochemists and molecular biologists, such as myself, look at how life works at the very most basic level. Unfortunately, this stuff is all very complicated and there are few resources online to explain how this work. Anastasia has a wonderful post about how Bt corn works in transformed plants, titled simply ‘Bt‘. In the post, she focuses on how the protein works from the angle of a plant biologist. […]

Harris T.J.C. & Tepass U. (2010). Adherens junctions: from molecules to morphogenesis, Nature Reviews Molecular Cell Biology, 11 (7) 502-514. DOI:

Lallès J.P. (2010). Intestinal alkaline phosphatase: multiple biological roles in maintenance of intestinal homeostasis and modulation by diet, Nutrition Reviews, 68 (6) 323-332. DOI:

Pardo-López L., Soberón M. & Bravo A. (2013). Bacillus thuringiensis insecticidal three-domain Cry toxins: mode of action, insect resistance and consequences for crop protection , FEMS Microbiology Reviews, 37 (1) 3-22. DOI:

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1:37 AM | Blue Brain Red Brain: Science predicts political preference
Which way does your moral compass point? When you read the news and suddenly feel a sense of injustice. Or outrage. Or more rarely, objectivity? When you write a check supporting the party of your choice. When you confidently select a box come election time. Why do you feel so strongly you have made the right choice? Science suggests we don’t have much choice, after all.

Kanai, R., Feilden, T., Firth, C. & Rees, G. (2011). Political Orientations Are Correlated with Brain Structure in Young Adults, Current Biology, 21 (8) 677-680. DOI:

Schreiber, D., Fonzo, G., Simmons, A., Dawes, C., Flagan, T., Fowler, J. & Paulus, M. (2013). Red Brain, Blue Brain: Evaluative Processes Differ in Democrats and Republicans, PLoS ONE, 8 (2) DOI:

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April 05, 2014

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8:53 PM | Can reducing ammonia production during exercise improve performance?
Ammonia may be a central player in fatigue and exhaustion.  Exercise releases of ammonia into the blood stream.  Once in the blood stream it travels to the brain where it can accumulate if the pace of entry is faster than the body’s ability to metabolize it.   Athletes in studies who had the hardest time completing […] The post Can reducing ammonia production during exercise improve performance? appeared first on WODMasters.

Qiu J, Tsien C, Thapalaya S, Narayanan A, Weihl CC, Ching JK, Eghtesad B, Singh K, Fu X, Dubyak G & McDonald C (2012). Hyperammonemia-mediated autophagy in skeletal muscle contributes to sarcopenia of cirrhosis., American journal of physiology. Endocrinology and metabolism, 303 (8) 93. PMID:

Nybo L, Dalsgaard MK, Steensberg A, Møller K & Secher NH (2005). Cerebral ammonia uptake and accumulation during prolonged exercise in humans., The Journal of physiology, 563 (Pt 1) 285-90. PMID:

Snow RJ, Carey MF, Stathis CG, Febbraio MA & Hargreaves M (2000). Effect of carbohydrate ingestion on ammonia metabolism during exercise in humans., Journal of applied physiology (Bethesda, Md. : 1985), 88 (5) 1576-80. PMID:

Bassini-Cameron, A., Monteiro, A., Gomes, A., Werneck-de-Castro, J. & Cameron, L. (2008). Glutamine protects against increases in blood ammonia in football players in an exercise intensity-dependent way, British Journal of Sports Medicine, 42 (4) 260-266. DOI:

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4:10 PM | U.Va. researchers turn embryonic stem cells into a fish embryo
The U.Va. researchers have created a zebrafish embryo using stem cells.Researchers at the University of Virginia School of Medicine have overcome one of the greatest challenges in biology and taken a major step toward being able to grow whole organs and tissues from stem cells.By manipulating the appropriate signaling, the U.Va. researchers have turned embryonic stem cells into a fish embryo, essentially controlling embryonic development.The research will have dramatic impact on the future use […]

Xu, P., Houssin, N., Ferri-Lagneau, K., Thisse, B. & Thisse, C. (2014). Construction of a Vertebrate Embryo from Two Opposing Morphogen Gradients, Science, 344 (6179) 87-89. DOI:

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3:50 PM | Light-activated neurons from stem cells restore function in paralyzed mice
A new method to artificially control muscles using light, with the potential to restore function to muscles paralyzed by conditions such as motor neuron disease and spinal cord injury, has been developed by scientists at UCL and King's College London.The technique involves transplanting specially-designed motor neurons created from stem cells into injured nerve branches. These motor neurons are designed to react to pulses of blue light, allowing scientists to fine-tune muscle control by […]

Bryson, J., Machado, C., Crossley, M., Stevenson, D., Bros-Facer, V., Burrone, J., Greensmith, L. & Lieberam, I. (2014). Optical Control of Muscle Function by Transplantation of Stem Cell-Derived Motor Neurons in Mice, Science, 344 (6179) 94-97. DOI:

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2:23 PM | The man with 1000 children: the limit of male fertility
By Greg Downey; (long read: 5500 words) Moulay Ismail ibn Sharif succeeded to the sultanate of Morocco after his brother fell from a horse and died in 1672. Twenty-six when he became the Sharifian Emperor, Moulay Ismael “the Bloodthirsty” — …The post The man with 1000 children: the limit of male fertility appeared first on Neuroanthropology.

Betzig L. (1992). Roman polygyny, Ethology and Sociobiology, 13 (5-6) 309-349. DOI:

Confer J.C., Easton J.A., Fleischman D.S., Goetz C.D., Lewis D.M.G., Perilloux C. & Buss D.M. (2010). Evolutionary psychology: Controversies, questions, prospects, and limitations., American Psychologist, 65 (2) 110-126. DOI:

Cooper T.G., Noonan E., von Eckardstein S., Auger J., Baker H.W.G., Behre H.M., Haugen T.B., Kruger T., Wang C. & Mbizvo M.T. & (2010). World Health Organization reference values for human semen characteristics, Human Reproduction Update, 16 (3) 231-245. DOI:

Einon D. (1998). How Many Children Can One Man Have?, Evolution and Human Behavior, 19 (6) 413-426. DOI:

FREUND M. (1963). Effect of frequency of emission on semen output and an estimate of daily sperm production in man, Reproduction, 6 (2) 269-286. DOI:

Gould R.G. (2000). How many children could Moulay Ismail have had?, Evolution and Human Behavior, 21 (4) 295-296. DOI:

Oberzaucher E., Grammer K. & Szolnoki A. (2014). The Case of Moulay Ismael - Fact or Fancy?, PLoS ONE, 9 (2) e85292. DOI:

Oldereid N.B., Gordeladze J.O., Kirkhus B. & Purvis K. (1984). Human sperm characteristics during frequent ejaculation, Reproduction, 71 (1) 135-140. DOI:

Shackelford T. & Goetz A. (2009). Sexual conflict in humans: evolutionary consequences of asymmetric parental investment and paternity uncertainty, Animal Biology, 59 (4) 449-456. DOI:

Valsa J., Skandhan K.P., Gusani P.H., Sahab Khan P. & Amith S. (2013). Quality of 4-hourly ejaculates - levels of calcium and magnesium, Andrologia, 45 (1) 10-17. DOI:

Woods D.C., Telfer E.E., Tilly J.L. & Barsh G.S. (2012). Oocyte Family Trees: Old Branches or New Stems?, PLoS Genetics, 8 (7) e1002848. DOI:

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2:02 PM | The immortality paradox
"Untold stories" © EEGThis is an old post, which I originally wrote in response to a friend's question. I'm reposting today because it's one of the topics you will discover in the plot of my detective thriller CHIMERAS, which will be released on Amazon next week. Here's the question my friend Tim raised:Is it true that our cells die and are replaced every 7 days? Now it is my understanding that as we age the memory of the cells is that of the previous cell’s age. Can we turn off […]

Jaskelioff M, Muller FL, Paik JH, Thomas E, Jiang S, Adams AC, Sahin E, Kost-Alimova M, Protopopov A, Cadiñanos J & Horner JW (2011). Telomerase reactivation reverses tissue degeneration in aged telomerase-deficient mice., Nature, 469 (7328) 102-6. PMID:

Hartwig FP, Bertoldi D, Larangeira M & Wagner MS (2014). Up-regulating telomerase and tumor suppressors: focusing on anti-aging interventions at the population level., Aging and disease, 5 (1) 17-26. PMID:

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11:11 AM | Curious publicity
Our conscious image of what we are seeing usually appears complete; it is the whole visual field. This is an illusion. The image is built up from many narrower views of parts of the scene that we attend to in rapid succession. Our visual system also establishes a knowledge of the general balance of the […]

Howe, P. & Webb, M. (2014). Detecting Unidentified Changes, PLoS ONE, 9 (1) DOI:

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9:21 AM | Blogger's Desk- What’s wrong with our science
Greetings      Lately, a few days ago I happened to stumble on an important point regarding “publication of research work”. Several blogs, podcasts, high level meetings, editorials etc.. are now pouring in opinions on how science is not working, the way it is supposed to. I have written on topics of very broad interest in this blog. Things that I have expressed below, is my personal opinion based on what I have found from polling (Link), talking in person to people […]

Bohannon J (2013). Who's afraid of peer review?, Science (New York, N.Y.), 342 (6154) 60-5. PMID:

Casadevall A & Fang FC (2014). Causes for the persistence of impact factor mania., mBio, 5 (2) PMID:

Siegel, V. (2008). The promise of peer review, Disease Models and Mechanisms, 1 (2-3) 73-77. DOI:

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8:16 AM | RCT Study on Dientamoeba fragilis in CID
In the string of papers coming out from Dr Dennis Röser’s PhD study on the epidemiology, transmission, and clinical significance of Dientamoeba fragilis, the most recent article was published a few days ago in Clinical Infectious Diseases and available (uncorrected proof) from the journal’s website here. DOI =  10.1093/cid/ciu188. Currently, the full text can be […]

Röser D, Simonsen J, Stensvold R, Olsen KE, Bytzer P, Nielsen HV & Mølbak K (2014). Metronidazole therapy for treating dientamoebiasis in children is not associated with better clinical outcomes: A randomized, double-blinded and placebo-controlled clinical trial., Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, PMID:

Röser D, Simonsen J, Nielsen HV, Stensvold CR & Mølbak K (2013). Dientamoeba fragilis in Denmark: epidemiological experience derived from four years of routine real-time PCR., European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology, 32 (10) 1303-10. PMID:

Röser D, Nejsum P, Carlsgart AJ, Nielsen HV & Stensvold CR (2013). DNA of Dientamoeba fragilis detected within surface-sterilized eggs of Enterobius vermicularis., Experimental parasitology, 133 (1) 57-61. PMID:

Clark CG, Röser D & Stensvold CR (2014). Transmission of Dientamoeba fragilis: pinworm or cysts?, Trends in parasitology, 30 (3) 136-140. PMID:

Stensvold CR, Clark CG & Röser D (2013). Limited intra-genetic diversity in Dientamoeba fragilis housekeeping genes., Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases, 18 284-6. PMID:

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7:07 AM | Weather extremes take twin crop and disease toll
Extreme rain has boosted harvests and droughts have harmed them, but both are linked to outbreaks of deadly viruses show NASA's Assaf Anyamba and his colleagues.

Anyamba, A., Small, J., Britch, S., Tucker, C., Pak, E., Reynolds, C., Crutchfield, J. & Linthicum, K. (2014). Recent Weather Extremes and Impacts on Agricultural Production and Vector-Borne Disease Outbreak Patterns, PLoS ONE, 9 (3) DOI:

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1:37 AM | Is your biological clock ticking? Maybe you should ignore it
As I've transitioned into middle age, I've gotten used to seeing my Facebook feed filled with baby pictures, descriptions of charming family outings, and adorable quotations from the mouths of toddlers. If I knew nothing about what it were like to have a child (mine is just finishing up the terrible twos), I would assume from scrolling through these perfectly tailored social media portraits of others' lives that having kids is a non-stop fun-filled procession of treasured moments. Of course, […]

Deaton, A. & Stone, A. (2014). Evaluative and hedonic wellbeing among those with and without children at home, Proceedings of the National Academy of Sciences, 111 (4) 1328-1333. DOI:

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April 04, 2014

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2:00 PM | The forgotten third and cosmic inflation
In the last days there has been an important breakthrough in physics and particularly in cosmology due to the publication of the results of […] Read more The post The forgotten third and cosmic inflation appeared first on Mapping Ignorance. Related posts:Quantum Thermodynamics I: Foundations and concepts Anti de Sitter space happens to be unstable Solid state physics could teach us how to quantize gravity: Horava’s theory

Starobinsky A.A. (1980). A new type of isotropic cosmological models without singularity, Physics Letters B, 91 (1) 99-102. DOI:

Brans C. & Dicke R.H. (1961). Mach's Principle and a Relativistic Theory of Gravitation, Physical Review, 124 (3) 925-935. DOI:

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1:17 PM | Why Do We Take Personality Tests?
I often get questions from friends and family that they would like answered in a post. This month, my post is inspired by a question from my grandmother. Kudos to my grandma for asking a question about a popular trend on the internet! […]

Gollwitzer, P. M. & Kirchhof, O. (1998). The Willful Pursuit of Identity, J. Heckhausen & C. S. Dweck (Eds.), Life-span perspectives on motivation and control., 389-423. Other: Link

Swann, W. B. (2012). Self-verification theory, In P. Van Lang, A. Kruglanski, & E.T. Higgins (Eds.) Handbook of Theories of Social Psychology,, 23-42. Other: Link

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