Posts

July 24, 2014

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8:14 AM | Prenatal valproate exposure and brains
The paper by Amanda Wood and colleagues [1] (open-access) makes a potentially very important contribution to the growing literature looking at how prenatal exposure to sodium valproate (VPA) may affect some children. Authors reported on: "regional structural cortical brain changes in humans exposed to VPA in utero" and specifically, increased cortical thickness in the left inferior frontal gyrus.Lightning and lava @ Oliver Spalt @ Wikipedia In case you need any background on the […]

Wood, A., Chen, J., Barton, S., Nadebaum, C., Anderson, V., Catroppa, C., Reutens, D., O'Brien, T. & Vajda, F. (2014). Altered cortical thickness following prenatal sodium valproate exposure, Annals of Clinical and Translational Neurology, DOI: 10.1002/acn3.74

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July 23, 2014

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7:26 PM | Physicians face difficult choices when treating patients with bipolar and obsessive compulsive disorders
New research suggests patients with both bipolar disorder and obsessive compulsive disorder should receive treatments for bipolar disorder alone.1 Bipolar and obsessive compulsive disorder therapies taken together can cause worsening of disease symptoms, making it difficult for physicians to treat both conditions. This is a concern as over 1 in 5 patients with bipolar disorder […]

Pacchiarotti I, Bond DJ, Baldessarini RJ & et al. (2013). The International Society for Bipolar Disorders (ISBD) task force report on antidepressant use in bipolar disorders., The American journal of psychiatry, 170 (11) 1249-62. PMID: http://www.ncbi.nlm.nih.gov/pubmed/24030475

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7:14 PM | Prototype Meter Tests Accuracy of Hydrogen Fuel Dispensers
Scientists at the National Institute of Standards and Technology (NIST) have developed a prototype field test standard to test the accuracy of hydrogen fuel dispensers.

Pope, J. & Wright, J. (2014). Performance of Coriolis meters in transient gas flows, Flow Measurement and Instrumentation, 37 42-53. DOI: 10.1016/j.flowmeasinst.2014.02.003

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5:41 PM | Wind Turbines Provide Feeding Opportunities for Wildlife
Scientists at the University of St Andrews have discovered that offshore pipelines and wind turbines can provide new feeding opportunities for the wildlife population in the area.

Russell, D., Brasseur, S., Thompson, D., Hastie, G., Janik, V., Aarts, G., McClintock, B., Matthiopoulos, J., Moss, S. & McConnell, B. & (2014). Marine mammals trace anthropogenic structures at sea, Current Biology, 24 (14) DOI: 10.1016/j.cub.2014.06.033

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5:21 PM | Voyager has hit interstellar space…. maybe?
Poor Voyager, he just can’t catch a break. We’ve said it’s hit interstellar space more times than we want to admit and in 2012, the Voyager mission team announced that […]

G. Gloeckler & L. A. Fisk (2014). A test for whether or not Voyager 1 has crossed the heliopause, Geophysical Research Letters, Other:

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5:13 PM | Preregistration for All Medical Animal Research
Writing in the European Journal of Clinical Investigation, three Dutch researchers say that All preclinical trials should be registered in advance in an online registry Citing the fact that all clinical trials are (in theory) already registered, authors Jansen of Lorkeers et al say that the system should be extended to cover preclinical medical research, […]The post Preregistration for All Medical Animal Research appeared first on Neuroskeptic.

Jansen of Lorkeers, S., Doevendans, P. & Chamuleau, S. (2014). All preclinical trials should be registered in advance in an online registry, European Journal of Clinical Investigation, DOI: 10.1111/eci.12299

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4:46 PM | As a butterfly flaps its wings in Tokyo, a neuron in your head veers slightly heavenward…
When you look at the edge of a table, there is a neuron in your head that goes from silence to pop pop pop. As you extend your arm, a nerve commanding the muscle does the same thing. Your retina has neurons whose firing rate goes up or down depending on whether it detects a light spot […]

Kaufman MT, Churchland MM, Ryu SI & Shenoy KV (2014). Cortical activity in the null space: permitting preparation without movement., Nature neuroscience, 17 (3) 440-8. PMID: http://www.ncbi.nlm.nih.gov/pubmed/24487233

Mante V, Sussillo D, Shenoy KV & Newsome WT (2013). Context-dependent computation by recurrent dynamics in prefrontal cortex., Nature, 503 (7474) 78-84. PMID: http://www.ncbi.nlm.nih.gov/pubmed/24201281

Churchland, M., Cunningham, J., Kaufman, M., Foster, J., Nuyujukian, P., Ryu, S. & Shenoy, K. (2012). Neural population dynamics during reaching, Nature, DOI: 10.1038/nature11129

Shenoy KV, Sahani M & Churchland MM (2013). Cortical control of arm movements: a dynamical systems perspective., Annual review of neuroscience, 36 337-59. PMID: http://www.ncbi.nlm.nih.gov/pubmed/23725001

Ames KC, Ryu SI & Shenoy KV (2014). Neural dynamics of reaching following incorrect or absent motor preparation., Neuron, 81 (2) 438-51. PMID: http://www.ncbi.nlm.nih.gov/pubmed/24462104

Churchland, M., Cunningham, J., Kaufman, M., Ryu, S. & Shenoy, K. (2010). Cortical Preparatory Activity: Representation of Movement or First Cog in a Dynamical Machine?, Neuron, 68 (3) 387-400. DOI: 10.1016/j.neuron.2010.09.015

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3:54 PM | The Adolescent Dog: One Last Chance?
A synthesis of the latest research on social influences on development suggests adolescence is an important time for mammals – including dogs.Photo: dezi / ShutterstockMost people are familiar with the idea of a sensitive period for puppies that ends around 12 or 14 weeks. Is it possible that adolescence is also an important period for brain development and future behaviour?Social experience plays an important role in shaping animal behaviour throughout development according to Sachser et […]

Riemer, S., Müller, C., Virányi, Z., Huber, L. & Range, F. (2014). The Predictive Value of Early Behavioural Assessments in Pet Dogs – A Longitudinal Study from Neonates to Adults, PLoS ONE, 9 (7) DOI: 10.1371/journal.pone.0101237

Sachser, N., Kaiser, S. & Hennessy, M. (2013). Behavioural profiles are shaped by social experience: when, how and why, Philosophical Transactions of the Royal Society B: Biological Sciences, 368 (1618) 20120344-20120344. DOI: 10.1098/rstb.2012.0344

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