Posts

October 01, 2014

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9:11 AM | Maternal complement C1q and offspring psychosis
"In conclusion, exposure to maternal C1q activity during pregnancy may be a risk factor for the development of schizophrenia and psychosis in offspring". That was the primary observation made by Emily Severance and colleagues [1] at Johns Hopkins, extending their scientific interest in immune system involvement being potentially linked to psychiatry [2]."Serve the public trust, protect the innocent, uphold the law"I've already talked about Dr Severance's previous research forays into complement […]

Emily G. Severance, Kristin L. Gressitt, Stephen L. Buka, Tyrone D. Cannon & Robert H. Yolken (2014). Maternal complement C1q and increased odds for psychosis in adult offspring, Schizophrenia Research, Other:

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September 30, 2014

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10:10 PM | New Immune System Discovery
The immune system is sort of this big enigma, we know how pieces of it work, but we don’t know it as well as we would like or we wouldn’t […]

Zhou RW, Mkhikian H, Grigorian A, Hong A, Chen D, Arakelyan A & Demetriou M (2014). N-glycosylation bidirectionally extends the boundaries of thymocyte positive selection by decoupling Lck from Ca2+ signaling., Nature immunology, PMID: http://www.ncbi.nlm.nih.gov/pubmed/25263124

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8:47 PM | Ritratti: Winifred Edgerton Merrill
Winifred Edgerton Merrill fu la prima americana ad ottenere un dottorato in matematica presso la Columbia University nel 1886. Nella sua tesi sviluppò una rappresentazione geometrica degli infinitesimi in diversi sistemi di coordinate, utilizzando lo jacobiano per per derivare le trasformazioni tra gli integrali nei diversi sistemi.Tra matematica e astronomiaNata a Ripon, nel Wisconsin, il 24 settembre del 1862 da Emmet e Clara Edgerton, si trasferisce con la famiglia a New York intorno […]

Kelly S.E. & Rozner S.A. (2012). Winifred Edgerton Merrill: "She Opened the Door", Notices of the American Mathematical Society, 59 (04) 504-512. DOI: http://dx.doi.org/10.1090/noti818

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8:13 PM | How space dust teaches us about scientific progresses
Sometimes I feel that it sucks to be a physicist. (Just to clarify – I am not one, and this is my personal opinion, having worked years in a department full of physicists, and with a background in non-physics fields. This is not after any discussion with other physicists in my dept – they might agree, they might […]

Ade P.A.R., M. Amiri, D. Barkats, S. J. Benton, C. A. Bischoff, J. J. Bock, J. A. Brevik, I. Buder, E. Bullock & G. Davis & (2014). BICEP2. II. EXPERIMENT AND THREE-YEAR DATA SET, The Astrophysical Journal, 792 (1) 62. DOI: http://dx.doi.org/10.1088/0004-637x/792/1/62

Ade P.A.R., D. Barkats, S. J. Benton, C. A. Bischoff, J. J. Bock, J. A. Brevik, I. Buder, E. Bullock, C. D. Dowell & L. Duband & (2014). Detection of B-Mode Polarization at Degree Angular Scales by BICEP2, Physical Review Letters, 112 (24) DOI: http://dx.doi.org/10.1103/physrevlett.112.241101

Planck Collaboration, R. Adam, P. A. R. Ade, N. Aghanim, M. Arnaud, J. Aumont, C. Baccigalupi, A. J. Banday, R. B. Barreiro, J. G. Bartlett & N. Bartolo (2014). Planck intermediate results. XXX. The angular power spectrum of polarized dust emission at intermediate and high Galactic latitudes, arXiv: http://arxiv.org/abs/1409.5738v1

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4:25 PM | This Month in Blastocystis Research (SEP 2014)
Before leaving for Venice and Padova to introduce Blastocystis to the XXX National Congress of The Italian Society of Protistology (ONLUS), allow me to kick in just a few words for the September issue of 'This Month in Blastocystis Research'.I will highlight two papers.The first is a study from the US (Yes, - US data! How rare is that?). The team investigated the prevalence and subtype distribution of Blastocystis among client-owned and shelter-resident cats and dogs. Studies of Blastocystis in […]

Krogsgaard LR, Engsbro AL, Stensvold CR, Vedel Nielsen H & Bytzer P (2014). The Prevalence of Intestinal Parasites is not Greater Among Individuals with IBS: a Population-Based Case-Control Study., Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association, PMID: http://www.ncbi.nlm.nih.gov/pubmed/25229421

Krogsgaard LR, Engsbro AL & Bytzer P (2013). The epidemiology of irritable bowel syndrome in Denmark. A population-based survey in adults ≤50 years of age., Scandinavian journal of gastroenterology, 48 (5) 523-9. PMID: http://www.ncbi.nlm.nih.gov/pubmed/23506174

Ruaux CG & Stang BV (2014). Prevalence of Blastocystis in Shelter-Resident and Client-Owned Companion Animals in the US Pacific Northwest., PloS one, 9 (9) PMID: http://www.ncbi.nlm.nih.gov/pubmed/25226285

Wang W, Cuttell L, Bielefeldt-Ohmann H, Inpankaew T, Owen H & Traub RJ (2013). Diversity of Blastocystis subtypes in dogs in different geographical settings., Parasites & vectors, 6 215. PMID: http://www.ncbi.nlm.nih.gov/pubmed/23883734

Wawrzyniak I, Poirier P, Viscogliosi E, Dionigia M, Texier C, Delbac F & Alaoui HE (2013). Blastocystis, an unrecognized parasite: an overview of pathogenesis and diagnosis., Therapeutic advances in infectious disease, 1 (5) 167-78. PMID: http://www.ncbi.nlm.nih.gov/pubmed/25165551

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9:06 AM | Autoimmune thyroiditis and depressive disorder
"Our study demonstrates a strong association between anti-TPO levels, which are considered to be of diagnostic value for autoimmune thyroiditis... with uni- or bipolar depression.""Beware the bad cat bearing a grudge"So said the study published by Detlef Degner and colleagues [1]. Anti-TPO antibodies by the way, refers to anti-thyroid peroxidase antibodies which, as the name suggests, are antibodies against thyroid peroxidase, an important step in the production of thyroid […]

Degner D, Haust M, Meller J, Rüther E & Reulbach U (2014). Association between autoimmune thyroiditis and depressive disorder in psychiatric outpatients., European archives of psychiatry and clinical neuroscience, PMID: http://www.ncbi.nlm.nih.gov/pubmed/25193677

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4:18 AM | Conscious content
I have been thinking about some information in a not too recent paper. (see citation below) Panagiotaropoulos and others looked at the location of the content of consciousness in primates. They used binocular flash suppression (BFS) to give two different visual stimulation that compete for a place in the content of consciousness. Here is their […]

Panagiotaropoulos, T., Deco, G., Kapoor, V. & Logothetis, N. (2012). Neuronal Discharges and Gamma Oscillations Explicitly Reflect Visual Consciousness in the Lateral Prefrontal Cortex, Neuron, 74 (5) 924-935. DOI: 10.1016/j.neuron.2012.04.013

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12:52 AM | There’s nothing quite like renewables: Modeling indicates natural gas production will not reduce future greenhouse gas emissions as hoped
Appropriate and useful climate policy-making requires accurate and reliable data about the future.  Nowhere is this more important than when setting carbon emission standards and projecting percentages of each energy source to match energy needs (coal, natural gas, nuclear, renewables, etc.). … Continue reading →

Steven J Davis and Robert H Socolow (2014). Commitment accounting of CO2 emissions, Environmental Research Letters, 9 (084018)

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September 29, 2014

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9:12 PM | New Protein Implicated in Alzheimer’s
Alzheimer’s prevention has made some strides in recent years. We’ve even identified some new causes, and in some cases we can do both. In fact, researchers have now shown that low […]

Minami, S., Min, S., Krabbe, G., Wang, C., Zhou, Y., Asgarov, R., Li, Y., Martens, L., Elia, L., Ward, M. & Mucke, L. (2014). Progranulin protects against amyloid β deposition and toxicity in Alzheimer's disease mouse models, Nature Medicine, DOI: 10.1038/nm.3672

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7:04 PM | Wind Turbines Kill Bats by Impersonating Trees
Survival tip: don’t hang around machines that have giant spinning blades. It’s a lesson bats have been slow to learn, judging by the large numbers of their corpses found beneath wind turbines. New video footage suggests some bats are attracted to wind farms because they can’t tell turbines apart from trees. If it’s true, this […]The post Wind Turbines Kill Bats by Impersonating Trees appeared first on Inkfish.

Paul. M. Cryan, P. Marcos Gorresen, Cris D. Hein, Michael R. Schirmacher, Robert H. Diehl, Manuela M. Huso, David T. S. Hayman, Paul D. Fricker, Frank J. Bonaccorso, Douglas H. Johnson & Kevin Heist (2014). Behavior of bats at wind turbines, PNAS, Other:

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8:35 AM | Term vs. preterm birth and the presentation of autism
The paper by Katherine Bowers and colleagues [1] continues the interest in the concept of 'the autisms' with their observations on the presentation of autism (and its comorbidities) when looking at those "born preterm versus those born at term".We'd better get back, 'cause it'll be dark soon, and they mostly come at night... mostlyBased on an analysis of quite a healthy participant number heading up to 900 "males and females with autism spectrum disorder", authors reported on several phenotypic […]

Bowers K, Wink LK, Pottenger A, McDougle CJ & Erickson C (2014). Phenotypic differences in individuals with autism spectrum disorder born preterm and at term gestation., Autism : the international journal of research and practice, PMID: http://www.ncbi.nlm.nih.gov/pubmed/25192860

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September 28, 2014

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7:37 PM | The Genetic Evolutionary Arms Race
Genes are tricky little buggers, the stuff that makes us up has fought the test of time to make it to where we are today. It is thought that our genes […]

Jacobs, Greenberg, Nguyen, Haeussler, Ewing, Katzman, Paten, Salama & Haussler (2014). An evolutionary arms race betweenKRAB zinc-finger genes ZNF91/93 and SVA/L1 retrotransposons, Nature, Other:

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8:54 AM | Andinobates Geminisae: New Fingernail Sized Poison Dart Frog from Panama
This is the hololotype specimen that the researchers used to describe the newly discovered Andinobates geminisaeCredit: Cesar Jaramillo, STRIA team of scientists from the Smithsonian Tropical Research Institute, the Universidad Autónoma de Chiriquí in Panama, and the Universidad de los Andes in Colombia recently announced the discovery of a new bright orange poison dart frog. The new species is so small that it can fit on a fingernail and was found in a rain forest near the […]

BATISTA, A., JARAMILLO, C., PONCE, M. & CRAWFORD, A. (2014). A new species of Andinobates (Amphibia: Anura: Dendrobatidae) from west central Panama, Zootaxa, 3866 (3) 333. DOI: 10.11646/zootaxa.3866.3.2

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September 27, 2014

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11:54 PM | How to Look for Pine Marten
The pine marten (Martes martes) is one of Ireland’s most beautiful but elusive mammals. It is notoriously difficult to see as it tends to be mostly nocturnal, and is a naturally shy animal. It is about the size of a … Continue reading →

O’Mahony, D., O’Reilly, C. & Turner, P. (2012). Pine marten (Martes martes) distribution and abundance in Ireland: A cross-jurisdictional analysis using non-invasive genetic survey techniques, Mammalian Biology - Zeitschrift für Säugetierkunde, 77 (5) 351-357. DOI: 10.1016/j.mambio.2012.04.001

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11:54 PM | How to Look for Pine Marten
The pine marten (Martes martes) is one of Ireland’s most beautiful but elusive mammals. It is notoriously difficult to see as it tends to be mostly nocturnal, and is a naturally shy animal. It is about the size of a … Continue reading →

O’Mahony, D., O’Reilly, C. & Turner, P. (2012). Pine marten (Martes martes) distribution and abundance in Ireland: A cross-jurisdictional analysis using non-invasive genetic survey techniques, Mammalian Biology - Zeitschrift für Säugetierkunde, 77 (5) 351-357. DOI: 10.1016/j.mambio.2012.04.001

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6:18 PM | Sometimes choices are not thought out
In some competitive situations animals can produce random behavior rather than behavior based on prior experience. The anterior cingulate cortex is where strategies based on models of reality and history are generated; switching to random behavior is done by inputs to this part of the brain from the locus coeruleus. This was reported in a […]

Tervo, D., Proskurin, M., Manakov, M., Kabra, M., Vollmer, A., Branson, K. & Karpova, A. (2014). Behavioral Variability through Stochastic Choice and Its Gating by Anterior Cingulate Cortex, Cell, 159 (1) 21-32. DOI: 10.1016/j.cell.2014.08.037

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5:29 PM | Are Black Holes just in Our Imagination?!
Black holes, physicists have been fighting over them forever, heck there is even a book entitled the black hole war! (which I do recommend for anyone interested) It’s no real […]

Laura Mersini-Houghton (2014). Backreaction of Hawking Radiation on a Gravitationally Collapsing Star I: Black Holes?, Physics Letters B, arXiv: http://arxiv.org/abs/1406.1525v1

Laura Mersini-Houghton, Harald P. Pfeiffer (2014). Back-reaction of the Hawking radiation flux on a gravitationally collapsing star II: Fireworks instead of firewalls , Physics Letters B, Other:

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12:37 PM | The Memory Fades, The Emotion Remains
People with Alzheimer’s disease can experience severe memory impairments.However, according to a new study, the emotions associated with events can persist long after the events themselves have been forgotten: Feelings Without Memory in Alzheimer Disease In their paper, the researchers, University of Iowa neurologists Edmarie Guzman-Velez and colleagues, showed volunteers a series of emotional video […]The post The Memory Fades, The Emotion Remains appeared first on Neuroskeptic.

Guzmán-Vélez E, Feinstein JS & Tranel D (2014). Feelings without memory in Alzheimer disease., Cognitive and behavioral neurology : official journal of the Society for Behavioral and Cognitive Neurology, 27 (3) 117-29. PMID: http://www.ncbi.nlm.nih.gov/pubmed/25237742

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7:50 AM | Yes, people with autism do have headaches
I don't mean to be haughty but a sentence included in the paper by Victorio [1] led to the title of today's very quick post. Based on a chart review of patients diagnosed with an autism spectrum disorder (ASD) attending a neurology clinic, the author concluded that "ASD patients, despite being known to have indifference to pain, can experience headaches".Pain is something which has cropped up quite a bit in the autism research arena and has appeared more than once on this blog (see here and see […]

Victorio, M. (2014). EHMTI-0290. Headaches in patients with autism spectrum disorder, The Journal of Headache and Pain, 15 (Suppl 1) DOI: 10.1186/1129-2377-15-S1-B37

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September 26, 2014

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6:15 PM | “GMO” Foods (Once Again) Proven Safe
GMO, I shudder every time I hear someone talk about the “dangers”. It’s one of the new buzzwords that doesn’t actually mean anything, but still manages to scare people. Well […]

Van Eenennaam AL & Young AE (2014). Prevalence and impacts of genetically engineered feedstuffs on livestock populations., Journal of animal science, PMID: http://www.ncbi.nlm.nih.gov/pubmed/25184846

Hirschberg, J. (2001). Carotenoid biosynthesis in flowering plants, Current Opinion in Plant Biology, 4 (3) 210-218. DOI: 10.1016/S1369-5266(00)00163-1

Paine JA, Shipton CA, Chaggar S, Howells RM, Kennedy MJ, Vernon G, Wright SY, Hinchliffe E, Adams JL, Silverstone AL & Drake R (2005). Improving the nutritional value of Golden Rice through increased pro-vitamin A content., Nature biotechnology, 23 (4) 482-7. PMID: http://www.ncbi.nlm.nih.gov/pubmed/15793573

Ahloowalia, B., Maluszynski, M. & Nichterlein, K. (2004). Global impact of mutation-derived varieties, Euphytica, 135 (2) 187-204. DOI: 10.1023/B:EUPH.0000014914.85465.4f

Brian P. Forster et al. (2001). Mutation genetics of salt tolerance in barley: An assessment of Golden Promise and other semi-dwarf mutants, Euphytica, DOI: 10.1007/978-94-015-9996-2_1

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2:30 PM | Walking Really Is Just Falling and Catching Yourself
The flailing of a gymnast who’s missed a step on the balance beam might not be far off from what the rest of us experience every day. Each step we take is really a tiny fall, a mathematical model suggests. The random-looking variation in our footfalls is actually a series of corrections. Our strides are […]The post Walking Really Is Just Falling and Catching Yourself appeared first on Inkfish.

Wang, Y. & Srinivasan, M. (2014). Stepping in the direction of the fall: the next foot placement can be predicted from current upper body state in steady-state walking, Biology Letters, 10 (9) 20140405-20140405. DOI: 10.1098/rsbl.2014.0405

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12:00 PM | Breaking Research: Fruit flies provide insights into metabolism and how we age
Why do we age? It’s more than just a philosophical question; it’s a puzzle that has frustrated scientists for decades. Currently, the most accepted hypothesis is that aging is the result of accumulated damage to our cells during our lifetime. “Accumulated damage” encompasses a variety of things that can go wrong, including DNA mutations, problems […]

Avanesov A.S., Kerry A Pierce, Sun Hee Yim, Byung Cheon Lee, Clary B Clish & Vadim N Gladyshev (2014). Age- and diet-associated metabolome remodeling characterizes the aging process driven by damage accumulation, eLife, 3 DOI: http://dx.doi.org/10.7554/elife.02077

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11:51 AM | Anthropomorphic Neuroscience Driven by Researchers with Large TPJs
For immediate release — SEPTEMBER 26, 2014Research from the UCL lab of Professor Geraint Rees has proven that the recent craze for suggesting that rats have “regrets” or show “disappointment” is solely due to the size of the left temporal-parietal junction (TPJ) in the human authors of those papers (Cullen et al., 2014). This startling breakthrough was part of a larger effort to associate every known personality trait, political attitude, and individual difference […]

Cullen, H., Kanai, R., Bahrami, B. & Rees, G. (2013). Individual differences in anthropomorphic attributions and human brain structure, Social Cognitive and Affective Neuroscience, 9 (9) 1276-1280. DOI: 10.1093/scan/nst109

Shabel, S., Proulx, C., Piriz, J. & Malinow, R. (2014). GABA/glutamate co-release controls habenula output and is modified by antidepressant treatment, Science, 345 (6203) 1494-1498. DOI: 10.1126/science.1250469

Steiner, A. & Redish, A. (2014). Behavioral and neurophysiological correlates of regret in rat decision-making on a neuroeconomic task, Nature Neuroscience, 17 (7) 995-1002. DOI: 10.1038/nn.3740

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9:30 AM | Cat and Dogs: seeking solutions with sniffing canines and science
Hi Mia and Julie,  First of all, I LOVE your blog! After meeting at SPARCS this past summer (summer for us in North America.. I take it summer is just beginning in Australia!), I’ve followed it closely.  You do amazing things for the promotion of  canine science. Serious love. A bit of background for the readers: I’m currently doing my PhD at Dalhousie University in Halifax, Nova Scotia in Canada, under the supervision of Dr. Simon […]

Brown S.W. & Strong V. (2001). The use of seizure-alert dogs, Seizure, 10 (1) 39-41. DOI: http://dx.doi.org/10.1053/seiz.2000.0481

Gonder-Frederick L., D. Warren, K. Vajda & J. Shepard (2013). Diabetic Alert Dogs: A Preliminary Survey of Current Users, Diabetes Care, 36 (4) e47-e47. DOI: http://dx.doi.org/10.2337/dc12-1998

Rooney N.J. & Claire Guest (2013). Investigation into the Value of Trained Glycaemia Alert Dogs to Clients with Type I Diabetes, PLoS ONE, 8 (8) e69921. DOI: http://dx.doi.org/10.1371/journal.pone.0069921

Matyka K.A. (2002). Sweet dreams? - nocturnal hypoglycemia in children with type 1 diabetes, Pediatric Diabetes, 3 (2) 74-81. DOI: http://dx.doi.org/10.1034/j.1399-5448.2002.30203.x

Wells D.L., Lawson S.W. & Siriwardena A.N. Canine responses to hypoglycemia in patients with type 1 diabetes., Journal of alternative and complementary medicine (New York, N.Y.), PMID: http://www.ncbi.nlm.nih.gov/pubmed/19040375

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8:00 AM | Suizid mit Koffein
Gegen 11 Uhr klingelte ihr Telefon. Sie schaute aufs Display und verdrehte genervt die Augen. Nicht der schon wieder! Ihr Ex hatte wieder einmal bei ihr übernachtet, weil sie es immer noch nicht über sich brachte, ihn rauszuschmeißen. Um 8 hatte sie ihn in ihrer Wohnung zurückgelassen und war zur Arbeit gegangen. Er hatte Probleme,…

Bonsignore A, Sblano S, Pozzi F, Ventura F, Dell'Erba A & Palmiere C (2014). A case of suicide by ingestion of caffeine., Forensic science, medicine, and pathology, 10 (3) 448-51. PMID: http://www.ncbi.nlm.nih.gov/pubmed/24771479

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7:00 AM | Eye contact makes us more aware of our own bodies
If you've ever felt acutely self conscious upon making eye contact with another person, a new study may help you understand why. Matias Baltazar and his colleagues have found that making eye contact activates people's awareness of their own bodies. That feeling of self consciousness induced by mutual gaze might be based in part on the fact that your brain is suddenly more attuned to your body.The researchers presented 32 participants with a series of positive and negative images on a computer […]

Baltazar M, Hazem N, Vilarem E, Beaucousin V, Picq JL & Conty L (2014). Eye contact elicits bodily self-awareness in human adults., Cognition, 133 (1) 120-7. PMID: http://www.ncbi.nlm.nih.gov/pubmed/25014360

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September 25, 2014

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2:37 PM | A New Discovery in the Treatment of Autoimmunity and Chronic Inflammation
Lupus, Type 1 diabetes, and multiple sclerosis are all diseases brought on by autoimmunity — the bodies inability to tell itself apart from foreign invaders. Finding a cure, or even a suitable […]

Dubiella C, Cui H, Gersch M, Brouwer AJ, Sieber SA, Krüger A, Liskamp RM & Groll M (2014). Selective Inhibition of the Immunoproteasome by Ligand-Induced Crosslinking of the Active Site., Angewandte Chemie (International ed. in English), PMID: http://www.ncbi.nlm.nih.gov/pubmed/25244435

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September 24, 2014

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10:08 PM | Profumo di particelle
Direi che oggi pomeriggio è stato un bel respirare, al Palazzo Brera. Cristina Lazzeroni dell'Università di Birmingham è venuta alle 18 (come avevo scritto nel post precedente) per raccontare del bosone di Higgs, del modello standard e di materia e antimateria. E' una sperimentale presso l'esperimento LHCb al CERN, l'esperimento dedicato proprio alla ricerca su uno dei grandi misteri dell'universo: perché in esso c'è un eccesso di materia (e d'altra parte se […]

Aaij R., B. Adeva, M. Adinolfi, C. Adrover, A. Affolder, Z. Ajaltouni, J. Albrecht, F. Alessio, M. Alexander & S. Ali & (2013). First Observation of CP Violation in the Decays of B_{s}^{0} Mesons, Physical Review Letters, 110 (22) DOI: http://dx.doi.org/10.1103/physrevlett.110.221601

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7:54 PM | A new Medicine may help Lupus Sufferers
Lupus, a particularly bad hell on earth for people suffering from it. Lupus is caused by autoimmunity, in where the body attacks itself. I have a special place in my […]

Wu T, Ye Y, Min SY, Zhu J, Khobahy E, Zhou J, Yan M, Hemachandran S, Pathak S, Zhou XJ & Andreeff M (2014). Targeting multiple signaling axes and oxidative stress using a synthetic triterpenoid prevents murine lupus nephritis., Arthritis & rheumatology (Hoboken, N.J.), PMID: http://www.ncbi.nlm.nih.gov/pubmed/25047252

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September 23, 2014

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10:40 PM | A shale’s life: first life cycle assessment of shale gas used for electricity in Great Britain
An interesting article came out a few days ago in Applied Energy that is of particular importance because its directly relevant to current politics in Great Britain.  With an estimated 38 trillion cubic meters of shale gas estimated to be lurking underneath … Continue reading →

Stamford, L. & Azapagic, A. (2014). Life cycle environmental impacts of UK shale gas, Applied Energy, 134 506-518. DOI: 10.1016/j.apenergy.2014.08.063

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