Posts

August 08, 2014

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10:00 PM | Psychiatry and inflammation (again)
I'd like to bring two papers to your attention in today's very quick post."The Death Star plans are not in the main computer"First up is the article by Kahn & Sommer [1] (open-access) titled: 'The neurobiology and treatment of first-episode schizophrenia'. It's about as good a read as we have so far on the topic of "brain changes in the first phase of schizophrenia" and the various management options for first-episode schizophrenia. Outside of the very important fact that "It is highly […]

Kahn RS & Sommer IE (2014). The neurobiology and treatment of first-episode schizophrenia., Molecular psychiatry, PMID: http://www.ncbi.nlm.nih.gov/pubmed/25048005

Friedrich MJ (2014). Research on Psychiatric Disorders Targets Inflammation., JAMA : the journal of the American Medical Association, PMID: http://www.ncbi.nlm.nih.gov/pubmed/25054339

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7:00 AM | Toolkit for GP practices on reasonable adjustments to support people with learning disabilities
The past few years has seen the publication of a number of national reports which have highlighted the often poor response to people with learning disabilities by health services, (‘Death by Indifference’, ‘Healthcare for all’ ‘Six Lives’ investigation) which led to a number of key recommendations for improvement, including the need for reasonable adjustments in [read the full story...]
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6:30 AM | Can schools prevent eating disorders?
In 2012 there was a call from Parliament to research school interventions to reduce body dissatisfaction. Helen Bould reports on an RCT of school-based prevention programme for eating disorders, which highlights the need for more work in this area. The post Can schools prevent eating disorders? appeared first on The Mental Elf.

August 07, 2014

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10:41 AM | Reducing Impulsivity via 12 Step Mutual Aid Group Affiliation
AA helps to reduce Impulsivity by alcoholicsguide One constant in studies on addiction and in alcoholism, in particular is the  fundamental role played by impulsivity in these disorders. It is seen to be present in early use but appears to be … Continue reading →
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7:42 AM | Vitamin D and schizophrenia meta-analysed
It's been a few weeks since I last talked about vitamin D on this blog and some finding or other talking about a deficiency of the stuff. Indeed, the last occasion was the publication of the Eva Kočovská study (see here) talking about issues with vitamin D being present across quite a few people on the autism spectrum, continuing a research trend (see here).So as to remedy this vitamin D blogging deficiency, today I'm talking about the systematic review and meta-analysis […]

Valipour G, Saneei P & Esmaillzadeh A (2014). Serum Vitamin D Levels in Relation to Schizophrenia: A Systematic Review and Meta-Analysis of Observational Studies., The Journal of clinical endocrinology and metabolism, PMID: http://www.ncbi.nlm.nih.gov/pubmed/25050991

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6:30 AM | New study estimates that UK smokers with mental illness cost the economy £2.34 billion
This new study estimates that there are approximately 3 million smokers in the UK with mental illness, and the direct cost of treatment to the NHS in this population was £719 million in 2010. The total smoking-attributable costs for this group are estimated at £2.34 billion. The post New study estimates that UK smokers with mental illness cost the economy £2.34 billion appeared first on The Mental Elf.

August 06, 2014

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8:39 AM | Gastrointestinal response to A1 vs A2 milk
I want to talk about the findings from Ho and colleagues [1] today, and in particular their observation of: "differences in gastrointestinal responses in some adult humans consuming milk containing beta-casein of either the A1 or the A2 beta-casein type". If you're wondering why such a paper finds it's way on to a blog predominantly about autism research, well stay with me on this rather long blogging entry...Start your engines... @ Wikipedia Before progressing, I am going to put a […]

Ho, S., Woodford, K., Kukuljan, S. & Pal, S. (2014). Comparative effects of A1 versus A2 beta-casein on gastrointestinal measures: a blinded randomised cross-over pilot study, European Journal of Clinical Nutrition, DOI: 10.1038/ejcn.2014.127

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6:30 AM | Psychotherapy for depression in older adults: promising results, but insufficient good quality research
This recent meta-analysis confirms that psychotherapy has a moderate to high effect on depression in older adults. However, a note of caution is sounded because of publication bias and the low quality of several of the included studies. The post Psychotherapy for depression in older adults: promising results, but insufficient good quality research appeared first on The Mental Elf.

August 05, 2014

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4:31 PM | Parents of Young Athletes: Protect Your Child’s Brain in 8 Steps
When I was kid, I remember my dad scolding my brother and me when one of us decided to hold the other one upside-down. In that position, he reasoned, we could fall on our head. As a cognitive... -- Read more on ScientificAmerican.com
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10:30 AM | Demonstrating Neouroplasticity in Short-Term versus Long-Term Abstinent Alcoholics
Alcohol dependence is thought of as a disorder with an overwhelming impulsive and compulsive “drive” towards alcohol consumption (Kamarajan et al. 2005), and an inability to “hit the brakes”, or inhibit alcohol consumption despite negative biological, psychological, legal, and social … Continue reading →
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8:05 AM | Bipolar disorder is frequent in adult Asperger syndrome
"BD [bipolar disorder] in AS [Asperger syndrome] patients is frequent, usually it onsets during adolescence and is often characterized by atypical presentation, making its correct identification particularly difficult".Maybe I'm better suited as a brunette? @ WikipediaThat was the primary finding reported by Vannucchi and colleagues [1] based on their systematic review of the relevant peer-reviewed research literature in this area. They found that the prevalence of BD ranged […]

Vannucchi G, Masi G, Toni C, Dell׳Osso L, Erfurth A & Perugi G (2014). Bipolar disorder in adults with Asperger׳s Syndrome: A systematic review., Journal of affective disorders, 168C 151-160. PMID: http://www.ncbi.nlm.nih.gov/pubmed/25046741

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6:30 AM | Statins have no beneficial effect on cognition in dementia, but can cause serious side-effects
This updated Cochrane review on statins for the treatment of dementia contains worrying adverse effects data, but Caroline Struthers has to do a significant amount of digging to root it all out. The post Statins have no beneficial effect on cognition in dementia, but can cause serious side-effects appeared first on The Mental Elf.

August 04, 2014

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2:43 PM | Unpacking Eating Disorder Recovery Part 1: The Recovery Model
What does eating disorder recovery really look like? When you say the word “recovery,” differences of opinion loom large. The lack of definitional clarity around the concept of recovery came up many times at ICED, and continues to surface in discussions among researchers, clinicians, and individuals with eating disorders themselves. We’ve looked at recovery on the blog before (for example, Gina looked at how patients define recovery here; Tetyana surveyed […]

Dawson L, Rhodes P & Touyz S (2014). The recovery model and anorexia nervosa., The Australian and New Zealand journal of psychiatry, PMID: http://www.ncbi.nlm.nih.gov/pubmed/24927735

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8:10 AM | Stopping gliadin peptides in their tracks?
A micropost if you will, to bring to your attention the paper by Marco Sarno and colleagues [1] and their suggestion of "a novel effect of probiotics in the prevention of undigested gliadin peptides toxic effects".Knitting on't Moors @ Wikipedia The probiotic in question is something called Lactobacillus paracasei CBA L74, which if I'm not mistaken is connected with a certain '57 varieties' company. The authors (which included one Alessio Fasano) indicated that said probiotic […]
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7:00 AM | Staff supporting people ageing with learning disabilities identify their needs for training
Last week we posted a second blog about a project aimed at helping older people with learning disabilities have an active and inclusive retirement. The number of people with learning disabilities in England aged over 60 continues to rise with the most recent predictions suggesting that by 2030 the number of adults aged over 70 [read the full story...]
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6:30 AM | Homelessness and mental illness in children and young people
This study explores the prevalence of psychiatric disorder and comorbidity among a UK sample of young people with experience of homelessness. It finds an extremely high prevalence of mental illness, combined with low levels of mental health service use. The post Homelessness and mental illness in children and young people appeared first on The Mental Elf.

August 03, 2014

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5:11 AM | Barefoot Water Skiing
Never saw this before. Barefoot water skiing. Didn’t believe it. Here is a behind the scene video: http://youtu.be/rezN4lfcs38  

August 01, 2014

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10:41 AM | Prolonged Abstinence and Changes in Alcoholic Personality?
                  Guest Blog Measuring the “Psychic” Change by alcoholicsguide Prolonged Abstinence and Changes in Alcoholic Personality? When I came into AA I remember hearing the words “the need for a psychic change” which … Continue reading →
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7:46 AM | Restricted and repetitive behaviours disappeared? More optimal outcome and autism
Today I'm bringing to your attention the paper by Eva Troyb and colleagues [1] and the quite dramatic assertion: "Reports of current behavior indicated that RRB's [restricted and repetitive behaviors] had almost totally disappeared in the OO [optimal outcomes] group". RRBs just in case you might not know include quite an array of behaviours, some of which might not be considered 'disabling' such as the presence of certain circumscribed interests. Others, such as an […]
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7:00 AM | Supporting older people with learning disabilities with inclusive retirement
A short while ago, we posted about the reflections of mentors in a programme in Australia aimed at helping older people get connected to and take part in community groups. The paper we are posting about today draws on data from that project. The researchers developed the project in the context of increasing numbers of [read the full story...]
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6:30 AM | Schizophrenia and genetics: a new landmark study
Genome-wide association studies have proved extremely successful in identifying reliable genetic associations with a number of disease outcomes, but until now studies of psychiatric outcomes have lagged behind. This latest schizophrenia study is therefore an important advance. The post Schizophrenia and genetics: a new landmark study appeared first on The Mental Elf.
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5:49 AM | Twitter Psychosis
This abstract came up in my RSS feed, I was flabbergasted. Could that be true. Is it internet addiction or video game addiction all over again? Reading the full article showed the authors have very little to back up their suggested causal relation between twitter and psychosis. Other factors could more likely contribute to the […]
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5:22 AM | Cocoa workers tasting chocolate for the first time
The farmers who harvest cocoa beans for a few cents in the Ivory Coast never tasted chocolate. Watch their faces when they eat it for the first time. For us westerners chocolate is just one more thing. It’s inconsequential. We like to eat it, sometimes we get delighted by it for a minute. But more […]

July 31, 2014

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11:18 PM | Serious Restrictive Eating Disorders Occur at Any Weight
Although the words “anorexia nervosa” typically conjure up images of emaciated bodies, eating disorders characterized by dietary restriction or weight loss can — and do — occur at any weight. However, precisely because anorexia nervosa is associated with underweight, doctors are less likely to identify eating disorders among individuals who are in the so-called “normal” or above normal weight range, even if they […]

Lebow, J., Sim, L. & Kransdorf, L. (2014). Prevalence of a History of Overweight and Obesity in Adolescents With Restrictive Eating Disorders, Journal of Adolescent Health, DOI: 10.1016/j.jadohealth.2014.06.005

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8:18 AM | Dipeptidyl peptidase (DPP) IV and autism: supporting opioid-excess?
Serum levels of dipeptidyl peptidase (DPP) IV were found to be lower in children with autism compared to asymptomatic controls according to the study by Shahid Bashira & Laila AL-Ayadhi [1]. Based on analysis by ELISA, researchers concluded that "alterations in the plasma level of DPP IV play a role in the pathophysiology of autism".A sailor went to sea, sea, sea... @ Wikipedia Anyone who has followed the autism research scene for any length of time might have already heard […]

Bashir, S. & AL-Ayadhi, L. (2014). Alterations in plasma dipeptidyl peptidase IV in autism: A pilot study, Neurology, Psychiatry and Brain Research, 20 (2) 41-44. DOI: 10.1016/j.npbr.2014.03.001

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6:30 AM | Internet-based alcohol and cannabis prevention: Climate Schools and salami slicing
Matt Field summarises the findings of a recent cluster RCT that uses internet-based prevention (an Australian programme called Climate Schools) to reduce alcohol and cannabis use, truancy, psychological distress and moral disengagement. The post Internet-based alcohol and cannabis prevention: Climate Schools and salami slicing appeared first on The Mental Elf.
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5:33 AM | Adapt Your Digital Footprint
Things change, the way yoy think, feel and act will also change during your life. In that sense your digital footprint is always there. Start using the Internet at a later age usually has the advantage of being aware of temporality of things, thoughts and feelings. Students are usually not aware of their digital footprint […]

July 30, 2014

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9:48 AM | Predicting Resilience or Vulnerability to later Alcoholism?
What makes some children of alcoholics vulnerable, and some resilient? by alcoholicsguide I come from a family of four siblings, two of whom are alcoholic and two who are not. I have often wondered why this is the case? Why is … Continue reading →
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8:52 AM | Immunological effects from risperidone treatment in autism
The findings from Jai Eun Choi and colleagues [1] suggesting that use of the antipsychotic risperidone may impact on levels of certain cytokines - messenger cells of the immune system - in some cases of autism spectrum disorder (ASD) grabbed my attention recently. I've always been pretty interested in the complexity of the immune system when it comes to something like autism (see here) as well as the various examples of how many of the medications used to 'manage' aspects of […]

Choi JE, Widjaja F, Careaga M, Bent S, Ashwood P & Hendren RL (2014). Change in Plasma Cytokine Levels During Risperidone Treatment in Children with Autism., Journal of child and adolescent psychopharmacology, PMID: http://www.ncbi.nlm.nih.gov/pubmed/24828014

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6:30 AM | Joint crisis plans: cost-effective for whom?
Chris Sampson looks at the economic outcomes of a recent RCT of joint crisis plans to reduce compulsory treatment for people with psychosis. The study reports the potential for gains specifically among Black patients. The post Joint crisis plans: cost-effective for whom? appeared first on The Mental Elf.
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