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May we scrape your face for SCIENCE? I imagine this is not a question one generally expects to be asked when visiting his or her friendly neighborhood natural history museum. And yet it’s one we’ve asked on a fairly regular basis during public outreach events over the last few months at the Nature Research Center at the North Carolina Museum of Natural Sciences. You would be AMAZED (I know I have been) at the number of enthusiastic volunteers who have stepped right up to participate, […]
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From a virus' perspective, how do you translate your own messenger RNA (mRNA), whilst not allowing your host cell to continue manufacturing its own proteins, including those that might be detrimental to virus survival? It's a problem viruses have found various ways to overcome, often by manipulating the biology of the mRNAs, which have the following structure:
The classical polyadenylated mRNA ready for translation
Simply, an eIF4F cap-binding complex binds to the cap and a poly(A)
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Rubio, R., Mora, S., Romero, P., Arias, C. & Lopez, S. (2013). Rotavirus Prevents the Expression of Host Responses by Blocking the Nucleocytoplasmic Transport of Polyadenylated mRNAs, Journal of Virology, 87 (11) 6336-6345. DOI: 10.1128/JVI.00361-13
Piron, M. (1998). Rotavirus RNA-binding protein NSP3 interacts with eIF4GI and evicts the poly(A) binding protein from eIF4F, The EMBO Journal, 17 (19) 5811-5821. DOI: 10.1093/emboj/17.19.5811
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Screenshot from KSA Coronavirus update page # 7287 A barebones report (h/t to @Ironorehopper) appears today on the Saudi Ministry of Health website, announcing a 31st confirmed infection with the novel coronavirus. The following is machine translation. Register new cases for the new Corona virus in the eastern region July 07, 1434 Within the framework of continuous monitoring and epidemiological investigation of the new Corona virus, have been
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It’s still mildly ironic that diners in Silicon Valley, the IT creative center for the world, are only now being offer data about restaurant inspections. But three months after an NBC investigative unit exposed flaws in the system, the department … Continue reading →
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Nuts seem to have lots of Salmonella issues. The pathogen persists nicely in the low-moisture environment and the roasting process (which is done without water) makes the bug even more hardy. Peanut butter has had well-documented problems; so have pistachios … Continue reading →
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# 7286 The ECDC has updated their rapid risk assessment on the novel coronavirus (formerly nCoV) dubbed MERS-CoV, based on information received since their last update on May 7th. As we saw earlier in the day from the World Health Organization, the ECDC is warning that nasopharyngeal swabs are not an optimal sample collection method, and that deeper respiratory sampling may be required. Below you’ll find their press summary, links to
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Integrins modulate the infection efficiency of West Nile virus
West Nile virus (WNV) is a small, enveloped, single-stranded RNA virus in the family Flaviviridae. In the natural transmission cycle WNV circulates between mosquitoes as vectors and birds as reservoir hosts. WNV can infect a wide taxonomical range of vertebrate species but most of them do not sufficiently support virus replication for transmission. Disease symptoms rarely occur, except in humans and horses where WNV infections are
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Photo Credit WHO # 7285 An interesting and informative update today from the World Health Organization on the novel coronavirus (nCoV) – recently dubbed MERS-CoV - which has infected at least 40 people with ties to the Arabian peninsula. For the first time we learn that while many of the recent cases in Al-Ahsa are linked to a single health care facility, at least two cases in the community have been diagnosed without any apparent links to the
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Basic Preps: Emergency Weather Radio, First Aid Kit, Battery Lantern, Water storage # 7284 With the 2009 H1N1 pandemic behind us, and largely perceived as having been `mild’ by the public, the idea of planning for another pandemic seems to have fallen out of favor. Many people assume – since we went more than 40 years between the last two pandemics- that we now have decades before we need worry about another one. But nature
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This one is for you, Jac. Related articles New Image Page (mhrussel.wordpress.com) Image: E. coli on cellulosic biomass (mhrussel.wordpress.com) A proud day: I did it! Scene 1 from my bacteria animation (mhrussel.wordpress.com) Filed under: Bacteria, Education, Nature, STEM Tagged: Animation, Bacteria, bacteria as art, Biology, Microorganism, Nature, Science, STEM
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Robert Herriman of The Global Dispatch interviewed me this week on the H1N1 – H5N1 reassortant study that has been in the headlines: There was much written concerning the research published earlier this month in Science, where researchers from China’s Harbin Veterinary Research Institute reported creating an avian H5N1 (highly pathogenic) and pandemic 2009 H1N1 (easily transmissible) hybrid, that according to them, achieved airborne spread between [...]
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A CDC scientist uses a pipette to transfer H7N9 virus into vials for sharing with partner laboratories for public health research purposes. # 7283 Dr. Peter Sandman, and his wife and colleague Dr. Jody Lanard, together run The Peter M. Sandman Risk Communication Website. They provide consulting services to individuals, organizations, companies, and even governments – often during their worst public relations nightmares. Their website contains a wealth
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The cellular receptors and determinants that mediate entry of WNV are unclear to date.The post Integrins modulate the infection efficiency of West Nile virus appeared first on MicrobiologyBytes.
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The variety of foreign bodies in the rectum tests a surgeon's ingenuity to solve a myriad of geometric puzzles
So begins Major PT Mcdonald's 1976 paper, in which he has to deal with a patient with a somewhat unique problem.
The patient, a 49 year old baseball fan, who had serious trouble with his bowels ever since the Oakland A's won the world series in 1974. The doctors examined him, and noticed
" a firm, fixed, round object barely palpable which was lodged high in the
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McDonald M.P.T. & Rosenthal C.D. (1977). An unusual foreign body in the rectum—A baseball report of a case, Diseases of the Colon & Rectum, 20 (1) 56-57. DOI: 10.1007/BF02587455
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# 7282 The novel coronavirus, which first surfaced on the Arabian peninsula a little more than a year ago, has gone by a variety of names, including novel coronavirus, nCoV, hCoV-EMC, and (even worse for those of us with chronic carpel tunnel problems) betacoronavirus 2c EMC2012. About 10 days ago Martin Enserink brought us details of a new naming convention (see Picking A Novel Name For A Novel Virus) for the novel coronavirus, proposed by an international
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Just a notification about the extended abstract submission deadline for the 8th European Congress on Tropical Medicine and International Health which is now 20th of May, 2013. Her Royal Highness Crown Princess Mary of Denmark is Patron of the conference, which will take place 10-13 September, 2013, in Copenhagen.
The 5th Conference of the Scandinavian-Baltic Society for Parasitology will be held in conjunction with the TM&IH meeting.
Hope to see you at the conference...
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Seven cases of E. coli-related illness have been reported recently in the Stephens County area, public health officials said. Georgia Department of Public Health District 2 spokesman Dave Palmer told the Independent Mail the cases all have appeared in the … Continue reading →
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After being infected with E. coli for the second time in her life, a Seattle woman wants to make restaurant inspection reports in Washington as public as possible, modeling efforts in New York and California. Sarah Schacht told KING 5 … Continue reading →
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The Tampa Tribune says that Old McMicky’s Farm, the original petting zoo that survived while surrounding acreage was grabbed for development, only to succumb to an E. coli scare and a decline in visitors, has been resurrected – by a … Continue reading →
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Australia still has an egg problem; and it seems no matter how many outbreaks there are, how many people get sick, and how much business is lost, the cooks I talk with are fiercely committed to continue the use of … Continue reading →
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Sorenne been taking swimming lessons at this huge outdoor pool complex for over a year, and even with all the babies, I haven’t seen poop in the pool. But it happens, as shown by all those summertime Cryptosporidium outbreaks linked … Continue reading →
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WRAL cited Cumberland County health officials Thursday as noting that 44 people have symptoms consistent with salmonella infection, an increase from 16 first reported Tuesday. Thirty-six of the patients are from North Carolina and eight are out of state, officials … Continue reading →
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As South Australia cracks down on raw milk sales, the UK Food Standards Agency had dropped charges against The Moo Man after he agreed to stop selling the milk on non-farm premises. The Sussex Express explains London store Selfridges along … Continue reading →
