Posts

August 28, 2014

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6:27 PM | Visceral leishmaniasis-HIV coinfection: Time for Concerted Action
In 2013, PLOS Neglected Tropical Diseases decided to dedicate a special collection to VL-HIV co-infection. With Ed Zijlstra, Asrat Hailu, and myself as guest editors, they sent out a call for papers. Today the Visceral Leishmaniasis-HIV Collection is launched, …The post Visceral leishmaniasis-HIV coinfection: Time for Concerted Action appeared first on Speaking of Medicine.
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6:10 PM | The Science Of Mountain Climbing!
The Science Of Mountain Climbing! Mountain climbing is one of the most difficult sports, but it can be very rewarding. Trace is here today to discuss all of the aspects of climbing. Read More: Into Thin Air: Mountain Climbing Kills Brain Cells http://www.scientificamerican.com/article/brain-cells-into-thin-air/ “IN THE LATE 1890s in a laboratory atop a 4,554-meter peak inRead More »
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6:07 PM | Kidney Organ Allocation in the USA - Upcoming Changes!
This is a short video describing the current and new policies regarding deceased donor kidney allocation in the USA. These policies may significantly affect certain groups of patients and physicians must be aware of those in order to best represent their patients. For more details, also check prior blog.Link for the video here
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6:00 PM | Brain Zaps Boost Memory
Researchers who study memory have had a thrilling couple of years. Some have erased memories in people with electroshock therapy, …
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5:41 PM | Another reason to admire the naked mole rat
The naked mole rat is the longest lived rodent species (>31 years). Unlike most mammals, they seem resistant to many age-associated ailments until much later in life, making them an exciting model of healthy aging. They are also resistant to the development of cancer as mentioned in this prior post. According to the CDC, cardiovascular…
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5:23 PM | Hypokalemic Periodic Paralysis
A recent renal consult I encountered was a Cantonese gentleman with a classical symptomatic history for Hypokalemic Periodic Paralysis (HPP). He presented with a serum K of 1.4 mmol/l and profound weakness. Initially beginning in his teenage years, he had intermittent attacks of weakness lasting hours and affecting proximal muscle groups. Emergency department admissions invariably revealed low serum K.Many of us will know the classical features to look for in the history:High risk Asian […]
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5:07 PM | UK Govt. Strongly Advises Against Travel To Sierra Leone, Liberia & Guinea
Source OCHA   # 9014     A change in the advice  by the UK’s Foreign Office today now advises against all but essential travel to the three primary Ebola-stricken nations, and warns that as conditions deteriorate and air service to the region diminishes, it may become increasingly difficult for people to leave.     Foreign Office Sierra Leone, Guinea and Liberia travel advice update Published 28 August 2014 The UK has changed its travel […]
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4:51 PM | The Role of Culture in Health
Each year, the University of Pennsylvania sponsors a series of events throughout its campus focusing on a central theme chosen by faculty, staff and students. The focal point of the 2014-2015 academic year is Health. The Year of Health was chosen, in part, because of the national focus on health-care...
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4:41 PM | The Fix for Bad Slides: MORE SLIDES!
I love this slide-show about breaking dense slides into "layers of slides." I have been trying to get some colleagues to do something like this for awhile. Enjoy and please take this advice! by JonathanSchwabish.
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4:19 PM | Superfoods and breast cancer: Study takes a closer look at broccoli and green tea
Could a combination of broccoli sprouts and green tea offer protection against breast cancer — and transform hard-to-treat breast tumors into a type that responds to medication?A series of studies in the lab of UAB biologist Trygve Tollefsbol, Ph.D., D.O., have generated encouraging findings. Tollefsbol, who is also a senior scientist in the UAB Comprehensive Cancer Center, has shown that mice given sprouts in their chow and green tea polyphenols in their water are protected against tumor […]
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4:16 PM | The immortality enzyme? Telomerase fights aging, fuels cancer
In a lab in the heart of Campbell Hall, UAB biologist Trygve Tollefsbol, Ph.D., D.O., stores the secret to immortality.Trygve Tollefsbol is a renowned expert on telomerase, an enzyme thatplays crucial roles in determining our lifespans and fueling cancer growth.Telomerase, the enzyme in question, is a quirky character. Even though it is dormant most of the time, it appears to play a key role in all three of Tollefsbol’s main research interests: aging, cancer, and […]
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3:40 PM | Gambler Sub-types: Three Distinct Profiles
One method to advance understanding of a disorder is to use statistical modeling for sub-type or class analysis.Lia Nower and colleagues recently published the results of such an analysis from the large general population data-set known as the U.S. National Epidemiologic Survey on Alcohol and Related Conditions (NESARC).In this sample, 851 adults 18 years and older were identified with disordered gambling.This group then underwent a type of latent class statistical analysis known as the […]
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2:13 PM | Bt and Leukemia – Another Anti-GMO Myth
The headline of an article on the Organic Consumers Association proclaims, “New Study Links GMO Food To Leukemia.” The same article trumpets the thoroughly discredited Seralini study. The claim is not true, but is part of a pattern of behavior that is depressingly familiar. The pattern is not unique to anti-GMO activism. In fact, it [...]
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2:01 PM | NIH To Launch Trials On Ebola Vaccine Candidate
Credit CDC PHIL   # 9014   The story has been filtering through the news wires for a couple of hours, but the embargo has just come off the following NIH press release, which outlines the plans for testing this (and other) experimental vaccine candidates.   NIH to Launch Human Safety Study of Ebola Vaccine Candidate Trial is First in Series of Accelerated Safety Studies of Ebola Vaccines Embargoed for Release: Thursday, August 28, 2014, 9:30 a.m. EDT   […]
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1:07 PM | SEQC kills microarrays: not quite
I've been working with microarrays since 2000 and ever since RNA-seq came on the scene the writing has been on the wall. RNA-seq has so many advantages over arrays that we've been recommending them as the best way to generate differential gene expression data for a number of years. However the cost, and lack of maturity in analysis meant we still ran over 1000 arrays in 2013, but it looks like 2014 might be the end of the line. RIP: microarrays.A slew of RNA-seq papers were published in Nature […]
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1:00 PM | A summer of science journalism with the Wellcome Trust-New Statesman scholarship
 Earlier this year the Wellcome Trust and New Statesman announced a joint programme offering paid internships to aspiring science writers from traditionally underrepresented backgrounds. The recipients of the first two scholarships spent eight weeks working at New Statesman. Ajit Niranjan, tells us about the experience… This summer I worked as a science writer for the […]
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11:00 AM | Naturopathy vs. Science: Facts edition
This is another post in the naturopathy versus science series, where a naturopath’s advice is assessed against the scientific literature. When you think medicine, your first thought may be “physician”. But the practice of medicine today is a collaboration, as few health professionals, even physicians, can deliver health care completely independently. As a pharmacist I’ve […]
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10:57 AM | WHO Ebola Response Roadmap
    # 9013   With the Ebola outbreak in Western Africa continuing to accelerate, and the breadth and scope of the outbreak already greater than all previously described outbreaks combined, the World Health Organization has today released a 27 page PDF file outlining a roadmap to contain the outbreak over the next 6 to 9 months. This roadmap contains a number of assumptions, including:   This Roadmap assumes that in many areas of intense transmission the […]
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10:24 AM | Nigerian Setback: Two More Ebola Cases
  # 9012   Two days ago the Nigerian Ministry of Health was all but proclaiming victory over the introduction of Ebola to his country (see media report  Nigeria Has Contained Ebola, Minister of Health Says), but this morning is now facing fresh challenges as two new cases have been reported in the port city of Harcourt.   These two cases involve a doctor (now deceased) who treated a contact of the index case Patrick Sawyer, and his wife.  The MOH […]
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10:01 AM | WHO Ebola Update – August 28th
    # 9011   It has been more than a week since the last World Health Organization update on the Ebola situation in Africa, and so as one might expect, today’s catch-up report presents some pretty big numbers.   Between the 20th and 26th, nearly 600 new cases have been reported, and just over 200 additional deaths.   The situation in Liberia and Sierra Leone remains chaotic and confused, and these numbers should not be perceived as a full […]
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9:44 AM | Mackay On The NEJM MERS-CoV Transmission Study
Coronavirus – Credit CDC PHIL     # 9010     Last night the NEJM published a study looking at the transmission of the MERS coronavirus to secondary contacts within a household, penned by such notables as Dr. Christian Drosten and Dr. Ziad Memish. The study focused on 26 index cases and their 280 household contacts, and found a relatively low (12 cases, 4%) incidence of household transmission.   Additionally, of the 26 index cases, only 6 (23%) appeared […]
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7:34 AM | Nitric oxide and its possible implication in ME/CFS (Part 2 of 2)
Andrew Gladman explores the current and historic hypotheses relating to nitric oxide problems in ME/CFS. This second article in a 2-Part series puts nitric oxide under the microscope and explores what it is, what it does and why it is so frequently discussed in the world of ME/CFS. The focus of this article is to build upon the previous article and explore how the hypotheses surrounding ME/CFS and nitric oxide weigh up against one another. It is therefore advised […]
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4:01 AM | A bad day for antivaccinationists: A possible retraction, and the “CDC whistleblower” issues a statement
They say that truth is stranger than fiction. I never really necessarily believed it, but today is a day that might well serve as anecdotal evidence to support that adage. Indeed, the day was perfectly bookended by two major developments in the case of the so-called “CDC whistleblower,” the senior CDC scientist who, if you…
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2:20 AM | BiotechDueDiligence Journal Watch
Ebola OutbreakSpecial feature / homepage from the New England Journal of Medicine. You can also check out the FDA webpage dedicated to the Ebola crisis. $TKMR $SRPTMicrobiology: Microbiome science needs a healthy dose of skepticismWilliam Hanage. Nature.Efficacy of High-Dose versus Standard-Dose Influenza Vaccine in Older AdultsDiazGranados et al. New England Journal of Medicine. $SNYDesign of Phase I Combination Trials: Recommendations of the Clinical Trial Design Task Force of the NCI […]
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12:00 AM | Reading the new map of breast cancer
In 2012 a landmark study produced a new genetic 'map' of breast cancer - today, the same researchers reveal one way to read it.

August 27, 2014

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7:48 PM | Contraceptive Equity Summit grapples with family planning changes under Obamacare
The summit comes as public health officials across the country address changes in insurance coverage for patients following the implementation of the Affordable Care Act.
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5:12 PM | Cancer policies: Still room for improvement in Illinois
How did Illinois measure up in the American Cancer Society's new report on legislative activity to fight cancer? There's good news and bad news.
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5:00 PM | Immune boosting pills: the latest snake oil?
Head into any supermarket or chemist, and you will find shelves filled with all kinds of products. Some are useful, evidence-proven medications (such as aspirin), others are more palliative like sore throat lozenges. However, in recent years there has been a rise in what I will term “Immune pills” for this article. You have probably […] The post Immune boosting pills: the latest snake oil? appeared first on MostlyScience.
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3:54 PM | The Science of Cats and Dogs
The Science of Cats and Dogs Main Episode: http://youtu.be/5jLfJ2AfR-o Get the GMM Coffee Mug! http://dftba.com/product/1bv/Good-Mythical-Morning-Mug Get the GMM Signed Poster plus the GMM T-shirt! http://dftba.com/artist/26/Rhett–Link MAIN YOUTUBE CHANNEL: http://youtube.com/rhettandlink Listen to Ear Biscuits! iTunes: https://itunes.apple.com/podcast/ear-biscuits/id717407884 SoundCloud: https://soundcloud.com/earbiscuits JOIN the RhettandLinKommunity! http://bit.ly/rlkommunity LIKE us […]
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2:58 PM | Diagnostic Profile in Pathological Gamblers
Behavioral disorders like pathological gambling (PG) rarely occur alone as a single uncomplicated disorder.In a previous post, I noted the overlap of PG with personality disorder, anxiety disorder, depression, bipolar disorder and substance abuse.A recent study from Germany adds to our knowledge of the general diagnostic profile in the PG population.Erbas and Buchner reviewed German national data sources and other German studies to come up with a series of findings:Twelve month prevalence rates […]

Erbas B & Buchner UG (2012). Pathological gambling: prevalence, diagnosis, comorbidity, and intervention in Germany., Deutsches Arzteblatt international, 109 (10) 173-9. PMID: http://www.ncbi.nlm.nih.gov/pubmed/22470406

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