Posts

September 18, 2014

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5:00 PM | Mike Adams and “natural biopreparedness” against Ebola and pandemics
This one will be much shorter than usual, mainly because I was out late last night for a dinner function at which I was on a panel of breast cancer experts. I must admit, even after having been an attending surgeon for 15 years, it never ceases to make me feel a bit weird to…
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3:50 PM | Sanford-Burnham welcomes five new Trustees
Sanford-Burnham today announced the election of 5 new Trustees to our Board.
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3:11 PM | Genetics of Social Skills: Oxytocin Receptor Gene
Social neuroscience is an emerging emphasis in the field of neuroscience research.Social cognition is the subset of cognitive functions related to social processes and includes factors such as facial recognition, social memory and ability to form friendships and other social bonds.Impairment in social cognition is a known feature in autism, schizophrenia and other mental disorders. This type of impairment can produce significant problems in life adjustment, employment and human […]
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2:52 PM | Genetic Testing For All: Is It Eugenics?
In recent weeks, there’s been talk of three types of genetic testing transitioning from targeted populations to the general public: carrier screens for recessive diseases, tests for BRCA mutations, and non-invasive prenatal testing (NIPT) to spot extra chromosomes in fetuses from DNA in the maternal bloodstream.… Read the restThe post Genetic Testing For All: Is It Eugenics? appeared first on DNA Science Blog.
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1:45 PM | WHO Ebola Roadmap Update – Sept 18th
    # 9091 Although it has been two days since their last update, today’s Ebola roadmap appears to only add one day’s worth of data to the case count tally, with a jump of 372 cases between September 13th and 14th.   Deaths over the same period jumped by 167 cases.   The good news is that the situations in both Nigeria and Senegal appear to have stabilized, with no new cases reported in the month of September.  Several hundred contacts […]
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1:25 PM | Emotion Is Not the Enemy of Reason
This is a post about emotion, so — fair warning — I’m going to begin with an emotional …
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1:15 PM | The Science of Identifying Jack the Ripper!
The Science of Identifying Jack the Ripper! Support more videos like this at http://patreon.com/rebecca The full 30-min discussion will be available to + Patrons shortly! Daily Mail links: http://www.dailymail.co.uk/news/article-2746321/Jack-Ripper-unmasked-How-amateur-sleuth-used-DNA-breakthrough-identify-Britains-notorious-criminal-126-years-string-terrible-murders.html […]
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12:18 PM | BiotechDueDiligence Journal Watch
An overview of FDA-approved new molecular entities: 1827–2013Kinch et al. Drug Discovery Today. A Good Death — Ebola and SacrificeMugele and Priest. NEJM.Open Access to Clinical Trials DataKrumholz and Peterson. Journal of the American Medical Association.Analysis of “Real World” Sovaldi® (sofosbuvir) Use and Discontinuation RatesBrennan et al. Published by CVS Health $CVSAngiotensin–Neprilysin Inhibition versus Enalapril in Heart FailureMcMurray […]
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12:18 PM | CIDRAP Commentary: Health workers need optimal respiratory protection for Ebola
Credit CIDRAP   # 9090   Last night CIDRAP published what I suspect will become a highly controversial commentary, which urges a higher standard of PPE (Personal Protective Equipment) for Healthcare Workers (HCWs) dealing with suspected or confirmed Ebola cases.     In doing so, they also revive the `airborne’ transmission debate.   As things stand now, contact (gloves, gown) and droplet protection (surgical masks, eye protection) are […]
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12:12 PM | Artificial Sweeteners and Diabetes
A new study published in Nature is getting a lot of press, and it seems making a lot of people worried. The Nature News article discussing the study has the headline: Sugar substitutes linked to obesity. I think this headline is misleading. Here’s a breakdown of what the study does and does not tell us. [...]
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12:00 PM | In Honor of Dr. Elisabetta Ullu
Kasturi Haldar, PLOS Pathogens Editor-in-Chief, reflects on Elisabetta Ullu’s pioneering contributions to the understanding of molecular mechanisms of RNAi in T. brucei. On the eve of 25th anniversary of the premier Molecular Parasitology Meeting (MPM) held at the …The post In Honor of Dr. Elisabetta Ullu appeared first on Speaking of Medicine.
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11:37 AM | Biotech Reading List
Billionaire inventor Alfred Mann is on a missionStuart Pfeifer (Los Angeles Times)A somewhat glowing profile of the $MNKD on the occasion of thhe FDA approval of his AFREZZA inhaled insulin.Medicine's Manhattan Project: Can The World's Richest Doctor Fix Health Care?Matthew Herper (Forbes)Perhaps the most detailed profile so far of Patrick Soon-Shiong's NantHealth ventures.The "Purple Book" Makes its DebutKurt Karst (FDA Law Blog)John Maraganore: From “Prototypical Geek” To Canny […]
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9:30 AM | Childhood cancer research – what are the barriers?
We look at some of the challenges in running childhood cancer clinical trails.
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8:00 AM | Working life: Richard Coward
Dr Richard Coward is an MRC Senior Clinical Fellow and Head of Research for the School of Clinical Sciences at the University of Bristol. Here he tell us about his […]
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6:00 AM | Sustaining Health: Linking environment, nutrition and health
The Wellcome Trust is increasingly aware of the links between environment, nutrition and health. To help examine the role of science and technology on climate and health, and discuss potential levers for change, the Wellcome Trust is co-hosting an event to coincide with the UN Climate Summit in New York. Saskia Heijnen of the Trust’s […]
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5:00 AM | Missouri tackles primary care shortage with “assistant physicians”
A new law in Missouri will allow medical school graduates who have not completed a residency to practice in underserved areas. They will be able to call themselves “doctor” but will be licensed as “assistant physicians” with significant limitations on their practice. (The first link is to Senate Bill 716, the bill that was passed […]

September 17, 2014

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9:53 PM | The University of Chicago Medicine launches “Dare to C.A.R.E.”
The University of Chicago Medicine is launching a free heart and vascular disease screening program to identify individuals at risk -- and intervene early when treatment is most effective.
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7:25 PM | The bright side of free radicals
ROS control heart function through a paracrine system.
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7:22 PM | MSF: French Volunteer Infected With Ebola, Will Be Evacuated
  # 9089   Although MSF (Médecins Sans Frontières) has had hundreds of volunteers working in the Ebola Hot Zones for months, they have had an enviable safety record.  Up until today, no MSF volunteer has contracted the Ebola virus.  Sadly that exemplary record now falls, as we learn from the following translated press release from the MSF website.        Ebola: a French MSF volunteer infected in Liberia "September 17, […]
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6:21 PM | WHO GAR Notice On Enterovirus D68
    # 9088   Infectious diseases don’t observe political borders, and in this 21st century, can spread quickly around the globe.  The recent outbreak of EV-D68 which has been detected in at least a dozen US states has now apparently crossed into Canada (see Three B.C. enterovirus cases now confirmed, authorities say & Alberta Health Services confirms 18 cases of Enterovirus D68 ).     Respiratory cases in other Canadian cities are being […]
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4:29 PM | Saudi MOH Reports MERS Case In Taif
  # 9087   After taking most of July and August off, MERS is beginning to bubble up again in Saudi Arabia with a new case reported for the third day running, and the 6th case reported over the past 10 days.    This is also the second case reported from Taif – which is about 60 miles from Mecca – this week.   As usual, details on this case are scant, with no word as to the route of exposure.  With the start of the Hajj just over 2 weeks […]
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3:28 PM | Antidepressants Modulate Memory in the Healthy Brain
The mechanism of antidepressant drug response is not well understood.One theory posits antidepressant effects are only seen in those with clinical depression leaving the healthy brain unchanged.In a previous post, I outlined a study demonstrating effects of antidepressants on brain connectivity measures in the healthy brain.A recent fMRI study extends our understanding of the potential mechanisms for antidepressant drugs.CT Cerqueira and colleagues from Brazil studied the effects of the […]

Cerqueira CT, Sato JR, de Almeida JR, Amaro E Jr, Leite CC, Gorenstein C, Gentil V & Busatto GF (2014). Healthy individuals treated with clomipramine: an fMRI study of brain activity during autobiographical recall of emotions., Translational psychiatry, 4 PMID: http://www.ncbi.nlm.nih.gov/pubmed/24984192

Citation
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3:23 PM | Follow the Leader
I read a really interesting post on the Harvard Business Review’s blog yesterday titled, “Convincing Employees to Use New Technology.” Any regular reader of my blog knows that I’m fascinated with new technologies, behavior change, and the intersection of the two. I’m particularly interested in how they come into play in science and in libraries, the […]
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1:59 PM | Vietnam Reports Additional H5N6 Outbreaks In Poultry
Credit Wikipedia   # 9086   We continue to see reports out of both Vietnam (see Vietnam: More H5N6 Outbreaks In Poultry) and China (see China: H5N6 Outbreak In Heilongjiang Poultry) that the recently emerged H5N6 avian flu virus keeps popping up over a wide swath of Eastern Asia.    Previously low pathogenic versions of H5N6 have been reported around the world, including in the United States and Europe. But as we learned last Sunday (see Whole-Genome Sequence Of […]
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12:47 PM | A Great Save
Running along the Schulykill River Trail was a frequent outing for Todd Tewksbury, a 27-year-old mechanical engineer. So when he started his run last one evening last month, the last place he expected to end up was in the emergency room of the Hospital of the University of Pennsylvania. “I...
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12:44 PM | The Little Things | The Science of Love
The Little Things | The Science of Love In our previous episode of The Science of Love, we asked four couples to participate in an experiment on compliments. Here we talk to the couples to find out what kind of impact it had on them. Watch the episode here: http://youtu.be/opMQxa1JkuM Watch more episodes of TheRead More »
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12:21 PM | Privileged Antivaxxers
The Hollywood Reporter recently published what is mostly an exposé on privileged Hollywood parents who have elected to delay, limit, or avoid altogether immunizing their children. The most common headline coming out of this article is that some LA communities have vaccination rates at third-world levels, such as South Sudan. The issues raises many questions […]
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12:00 PM | It’s not just oil pulling, it’s ozone-infused oil pulling!
As I so love to remind my readers, I’ve been at this blogging thing a long time now. In early December, it will have been a full decade since that strange, cold, dreary winter afternoon (well, technically late fall) when, inspired by an article in TIME Magazine about blogging, sat down in front of my…
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11:37 AM | `Mystery Diseases’ In Hard To Verify Places
    # 9085   A day scarcely goes by where the dedicated volunteers at FluTrackers, the Flu Wiki, or ProMed Mail don’t come across a media report of an `unidentified disease’ raging in some remote part of the world.  Often initial news reports are either highly speculative, or just downright wrong, and so I approach these stories with caution.   Fever is, by the way, the most common presenting symptom of an infection, and FUO (Fever of Undetermined […]
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7:13 AM | Can You Come for a Visit? My ME/CFS Says No
New grandma Jody Smith shares her frustrations about not being able to visit the new baby… My daughter and son-in-law just had a baby last week. We are thrilled. But we won’t be able to see the baby or hold her any time soon. We won’t be able to take over little gifts or help out with housework or babysitting. The little family lives a province away and we can’t afford to make the trip. And that includes not being able to afford the energy it would require. People […]
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