Posts

December 09, 2014

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6:52 PM | Enzymes could be key for brain cancer and Alzheimer’s disease
Laszlo Nagy and his team recently discovered that enzymes called protein arginine methyl transferases 1 and 8 play key roles in regulating the effects of retinoic acid on gene activity and cellular specification.
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5:23 PM | Incentives in the Treatment of Cocaine Dependence
Relapse rates are high in treatment samples of adults with cocaine dependence.Cognitive behavioral therapy (CBT) is a common standard of care for cocaine dependence.A recent clinical trial from Switzerland examined the use of financial prize incentives to augment standard CBT in the treatment of cocaine dependence.Sixty subjects participated in this trial with the following inclusion criteria: least 18 years of age, had a DSM-IV diagnosis of cocaine dependence with at least one […]
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3:55 PM | Einstein’s Research Efforts to Fight Malaria
Editors’ Note: Malaria causes over 200 million new infections annually. Each year, more than 600,000 people die from the disease. The WHO estimates that an African child dies every minute from malaria. There has been progress, however. In April, the U.N. reported that malaria rates for children in Africa are down by half. Still, there is much to be [...]
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3:36 PM | Guest Post: Be Smart: Healthy Living Is In
This is a guest post by Darrell J. Hunt. Hope you enjoy it. Living a healthy lifestyle can add years to your life and increase happiness. Make these six healthy lifestyle choices habits that will benefit you for a lifetime. Eat More Fruits, Vegetables, and Whole Grains A healthy diet should include a wide range…
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3:01 PM | Top 100 papers of 2014: courtesy of Altmetric
Congratulations to Marc Tischkowitz and colleagues for getting into Altmetrics Top 100 papers of the year. Their NEJM paper on increase risk of breast cancer in loss-of-function PALB2 carriers was number 87 and one of two papers from the University of Cambridge.The Altmetric Top 100 is heavily influenced by the media coverage of "newsworthy" publications and it is perhaps not surprising that the Number1 spot is taken by Facebook's rather controversial "emotional contagion" paper (covered by […]
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3:00 PM | Candy Cane No. 9!
 December 9 - Go, Libraries, Go! I love a mobile library, a bookmobile, and biblioburros! Several years ago, my neighbor introduced me to the Mobile Library Mystery Series by the Northern Ireland author, Ian Sansom. The Case of the Missing Books got me hooked! I love the Little Free Library movement and book trading posts. I loved James […]
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1:14 PM | WHO Influenza At The Human-Animal Interface – December Update
WHO December Update # 9425   While Ebola and MERS have garnered much of the infectious disease attention over the past year, in terms of having pandemic potential, novel influenza viruses remain atop the list of viruses of most concern.   Over the past 125 years we’ve seen 6 pandemics arise, all presumably from reassortant avian or swine influenza viruses.   Of the novel viruses circulating in the wild, up until a couple of years ago, the avian H5N1 […]
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1:00 PM | No Permission Required
One of the most valuable things an academic can do requires no permission from your supervisor. While some departments and groups perform the activity formally, many faculty do it on their own. It should not be a solo activity, though. Strength comes from input from others. I am talking about the CV review. In The […]
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12:00 PM | How the Sense of Taste Works?
Taste, or gustatory perception, is one of our basic senses. It tells us from early childhood what is edible and what is not, what is good for our body and what can be potentially dangerous. Taking into account how important the sense of taste is for us, it is surprising how little we know about […]
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12:00 PM | Quackademic medicine marches on: Essential oils and quackademia for the poor
After having written about how the Society for Integrative Oncology (SIO) has promoted guidelines for cancer patients that are—shall we say?—less than scientifically rigorous, I was immediately confronted with just what we face in academic medicine when it comes to the infiltration of quackery, or, as I like to call it, quackademic medicine. It came…
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11:19 AM | Los Angeles Unveils Earthquake Retrofit & Resilience Plan
Resilient By Design PDF     # 9424   Last December, in Dr. Lucy Jones: `Imagine America Without Los Angeles’, we looked at a presentation given by noted seismologist Dr. Jones at the  annual meeting of the American Geophysical Union (held  in San Francisco),  that emphasized that should the `big one’ hit Southern California, we could literally `lose’ Los Angeles.   Dr. Jones warned that the damage could be far greater, and last […]
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10:46 AM | Wising up on older people and cancer
A new report has launched looking at what we know, and what we still need to understand, about cancer and older people in the UK - we look at the findings.
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10:18 AM | CFIA Sets Bird Flu Control Zones In BC
Credit Wikipedia – British Columbia   # 9423   Last night CFIA  (the Canadian Food Inspection Agency) outlined new steps to control the spread of the HPAI (Highly Pathogenic) H5N2 virus detected last week at 5 poultry operations in southern British Columbia.      Fully half of the province – everything south of Highway 16 – becomes part of the primary control zone.   Although no new farms have been announced as infected, […]
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8:00 AM | Pesticides: Just How Bad Are They?
I think everyone would agree that it would not be a good idea to put pesticides in a saltshaker and add them to our food at the table. But there is little agreement when it comes to their use in agriculture. How much gets into our food? What are the effects on our health? On […]

December 08, 2014

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10:57 PM | Genetically engineered insulin does not cause cancer in diabetics
I have a lot of issues with the pseudo-medicine pushed by many many websites whose sole purpose is to push woo, or nonsense, to their readers. Then they have links to buy junk medicine from their website. Natural News, Mercola, and others have become multimillionaires with this business model. These “entrepreneurs” deceive their readers with […]Continue reading «Genetically engineered insulin does not cause cancer in diabetics»
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10:12 PM | MAP-ping Networks That Control Cell Movement: Implications for Understanding Metastasis
Xiaoyang Wu and his team identify a cellular protein that plays a key role in metastasis, or how cancer cells spread to another part of the body.
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8:49 PM | 5 Things Fitness Experts Wish You Would Stop Doing in the Gym
I was a guest contributor on a recent top.me article surveying fitness experts about what they would wish people would stop doing when they go to the gym. I weigh in on #3 and #4. You can read the article here.
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8:40 PM | Médicos contra computadoras 2
Tarda pero llega. Sigo con la discusión del artículo: Do We Need Doctors or Algorithms? de Vinod Khosla, ¡que había empezado en febrero de 2012! En aquel entonces había prometido una segunda parte. El tema es vastísimo y claramente no me iba a dar para abordarlo de una,  pero fue quedando para atrás y recién ahora lo encaro de nuevo.Pueden leer la primera parte aquí (con algunas correcciones actuales, pero esencialmente […]
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8:36 PM | This year’s flu vaccine isn’t perfect, but you should still get a shot every year
After the CDC reported that this year's flu vaccine doesn't protect against some strains, we round up what our experts are saying about how the vaccine works, and why you should always get a shot anyway.
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8:31 PM | Cerebrovascular physiology – article alert #91
Migraine and brain blood flow 472- Migraine and cerebral blood flow in the general population – Loehrer et al. Orthostatic hypotension and the brain 473- Influence of nocturnal and daytime sleep on initial orthostatic hypotension – Lewis et al. Cerebrovascular regulation 474- Rapid pressure-to-flow dynamics of cerebral autoregulation induced by instantaneous changes of arterial CO2 […]
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5:09 PM | Young adults with acute lymphoblastic leukemia benefit from treatments developed for children
Results from a large clinical trial by Wendy Stock, MD, add to mounting evidence that adolescent and young adult patients ALL tend to fare better when treated with high-intensity pediatric protocols.
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4:32 PM | The FaLaLaLa Fallacies about Holiday Weight Gain
Despite the joy and festivity of the holiday season, this time of year has a bad reputation for people who are trying to lose weight—or even just avoid gaining weight. Amid the office parties, the family gatherings and all the baked goodies, the time between Thanksgiving and New Year’s Day...
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4:07 PM | Candy Canes 6, 7, and 8!
 December 6 - Share and Share Alike! One of the best characteristics of our profession is sharing. Librarians share things freely and openly. Unfortunately, I’m as guilty as anyone in too often forgetting this fact. Libraries, library organizations, and the like are GREAT places to find archives of useful materials. One of these is the archives […]
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3:40 PM | Saudi King Appoints New MOH Amid Sweeping Changes To Ministries
Saudi Arabia ****  UPDATED ****   # 9422   It was only last April that the long-standing  Minister of Health  Dr. Abdullah Al-Rabiah  was abruptly replaced by Dr. Adel bin Mohammed Faqih (see Saudi Minister Of Health Replaced), presumably over his inability to get control over their growing MERS problem.   Today we’ve word of a massive reshuffling of Cabinet Ministers in Saudi Arabia that includes replacements for the Ministers of Health […]
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3:14 PM | Saudi MOH Reports 1 MERS Case In Najran
  # 9421 Although not as big a focus point for MERS cases as Riyadh or Taif, Najran - near the Yemen border – has reported 1 or 2 cases a month since late in the summer.     The last case we saw reported was 6 days ago (link) – that of a 28 year old ex-pat with `animal exposure’.   Today, the MOH is reporting another case – a 61 year old male in critical condition.   While a source of infection has not been […]
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2:37 PM | A welcome review of how treatments get to patients
The UK Government has announced it will review the process for getting new cancer treatments to patients more quickly - so what happens next?
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12:10 PM | Genomes, exomes or amplicones: what's best for the clinic?
Clinical sequencing is looming and recently I've heard more, and better, arguments for using whole genomes. These have mainly focused on the quality of PCR-free genomes, which have uniform coverage and few regions of missing or very low coverage. Compared to the PCR and hybridisation-capture artefact's in exomes, or the focus on a biased set of genes a genome can sound very convincing (especially if you ignore the analysis/storage issues). Until recently the cost has still been too high, but […]
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12:04 PM | Wellcome Trust Research Round-up: 08.12.14
Our fortnightly round-up of research news from the Wellcome Trust community… Competition and climate change may help exotic parasites spread to UK honeybees Scientists have found that an exotic parasite out-competes its native relative when introduced into UK honeybees, which may lead to disease spreading in bees as our climate changes. The research, published in […]
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12:00 PM | Is the DSM-5 A “Book of Woe”?
The American Psychiatric Association (APA) published the first version of the Diagnostic and Statistical Manual of Mental Disorders (DSM) in 1952. Its ongoing aim is to establish a common language and standard criteria for the classification of mental disorders. Since the APA published the fifth edition of the DSM in May 2013, there has been […]
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10:05 AM | Molecular ‘safety-net’ stops tumour cell DNA being torn apart
We explore new research on how cancer cells divide, and a potential weakness that could be exploited to kill them.
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