Posts

November 21, 2014

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11:09 AM | Could computers help GPs diagnose cancer early?
We discuss results of an evaluation of a new computer based system to help GPs diagnose cancer.
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10:03 AM | Image of the Week: Freud’s Porcupine
In honour of The Institute of Sexology opening yesterday at Wellcome Collection, we’ve decided to showcase a very special object from the exhibition. This little porcupine has been gaining quite a bit of attention recently, but we feel that it is well deserved. What is the link between porcupines and sexology you may wonder? Whilst […]
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4:26 AM | Praise from Science Borealis
Thank you to the Science Borealis blog for making Science-Based Pharmacy an Editors’ Pick for 2014! The blog won in the category of “Health, Medicine and Veterinary Science“. Given the output and quality of other Canadian health professionals and colleagues that blog, I’m surprised and very grateful for the recognition. I’m a strong supporter of […]
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3:44 AM | Naturopathy and “biomedical” treatments for autism
For the past several months I’ve been contrasting the advice from naturopaths against the scientific evidence, in a series I’ve been calling “naturopathy versus science”.  In past posts I’ve looked at the naturopathic perspectives on fake diseases, infertility, prenatal vitamins, vaccinations, allergies and even scientific facts themselves. From a blogging perspective, naturopathy is a fascinating […]

November 20, 2014

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10:21 PM | EDELMAN IS THE ROOT OF ALMOST ALL GOOD IN NEPHROLOGY
Almost all the formulas we use in the management of the disorders of water homeostasis are derived from the Edelman equation. I am presenting where these formulas come from for the math aficionados.Edelman equation·         Original Edelman equation (J Clin Invest. 1958;37:1236-56): [Na+] = {1.1 x (Nae + Ke)/TBW} – 25.6Where [Na+] = plasma sodium concentration, Nae=total body exchangeable sodium, Ke=total body exchangeable potassium, TBW […]
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9:46 PM | A sense of deja vu: the advertising of e-cigarettes
Glamourising smoking, targeting advertising at young people, using imagery of healthy, sporty smokers – all old, outlawed techniques for the tobacco industry. But the advent of e-cigarettes has lit the embers of this debate again. The BMA has complained to the Advertising Standards Authority (ASA) about a television advertisement for e-cigarettes, saying it breaches two […]
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7:46 PM | What I Am Reading: Recent Airport Edition
I spent a bunch of time in airports recently (thanks, winter), and I read several books. Instead of trying to review each one separately, I will just list them with a short synopsis of my thoughts.  The Prince Lestat (Ann Rice)  Ann Rice abandoned her muse, the bad-boy Lestat, and wrote about other things for […]
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7:26 PM | ECDC Updated Rapid Risk Assessment On H5N8
H5N8 – A long way from home   # 9354   A week ago – when there was but one outbreak (in Germany) of HPAI H5N8 in Europe – the ECDC issued a Rapid Risk Assessment for EU Countries, noting that:   The public health threat from this event is considered very low. To date, no human infections with this virus have ever been reported world-wide and the risk for zoonotic transmission to the general public in the EU/EEA countries is considered to be extremely […]
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7:06 PM | The $1,000 Genome de Kevin Davies
The $1,000 GenomeThe Revolution in DNA Sequencing and the New Era of Personalized MedicineFree Press |  352 pages | ISBN 9781416569596 | September 2010Terminé de releerlo hace un par de días. Sigue siendo muy recomendable, si bien mucha agua ha pasado bajo el puente en estos últimos 4 años.
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6:41 PM | Egyptian Hospitals On Alert For H5N1
  # 9353   While Europe finds itself on the receiving end of a new H5N8 avian influenza virus this week, Egypt is fighting an old nemesis, the H5N1 virus. Unlike the emerging H5N8 virus, this venerable bird flu has a limited but deadly track record in humans.   H5N1 arrived in Egypt in eight years ago during the great bird flu expansion of 2006 (see H5N8: A Case Of Deja Flu?), and despite aggressive poultry vaccination schemes and attempts to discourage the raising of […]
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5:38 PM | Eurosurveillance: Avian H10N7 Influenza In Harbor Seals
  # 9352   Just about a month ago, in Avian H10N7 Linked To Dead European Seals, I wrote about the recent die off of seals in Denmark and Germany and the determination that their deaths were the result of a combination of avian H10N7 influenza, pneumonia, and bacterial infection.   In 2011 a similar die off of seals in New England made headlines, which was eventually linked to a different avian flu virus (see New England Seal Deaths Tied to H3N8 Flu Virus). In 2012, […]
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4:53 PM | Regeneron Builds a Database of Human Knockouts in Search for Drug Clues | MIT Technology Review
Regeneron Builds a Database of Human Knockouts in Search for Drug Clues | MIT Technology Review
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4:24 PM | Why Mentoring Makes a Difference to Medical Students and Faculty
A recent post on this blog by Dr. Yvette Calderon, associate dean for diversity enhancement at Albert Einstein College of Medicine, described the importance of mentors and role models as she navigated her way through the unfamiliar territory of medical school and residency in the 1980s. Now, one of her central roles is to act [...]
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4:20 PM | Saudi MOH Announces 4th MERS Case In Al-Kharj In A Week
  # 9351   The mini-outbreak in Al-Kharj continues, with the announcement of a 4th case – that of a 48 y.o. female (exposure unknown) who is reportedly in stable condition. The MOH also reports the death of an earlier announced 70 y.o. female from Taif.  
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4:02 PM | CDC: Best Practices On Procuring PPEs For Ebola Response
Packing PPE Container – Credit CDC   # 9350   One of the realities of living in a just-in-time inventory oriented world is that no one keeps large stockpiles of supplies on hand just in case an unusual demand arises.  Grocery stores which a couple of decades ago might have been restocked once or twice a week now received tailored deliveries (based on real-time data collected from their Point of Sale system) – several times a day. Hospitals, too, rely on […]
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3:59 PM | something something antibiotics something something
It's been a crazy couple weeks out here on the edge of the prairie. Clinical service, grants, papers, holidays, Ebola?, the ESCMID-SHEA course in Phuket and SHEA2015 have swallowed up my fall. Get those SHEA abstracts ready folks - the deadline is fast approaching - January 16th.In the middle of this chaos, the CDC's Get Smart About Antibiotics Week seemingly appeared out of nowhere and CDDEP investigators just published a very nice antibiotic use point prevalence study in 6 US […]
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3:43 PM | Copy-number: exomes vs genomes, proposing a better strategy
Comparing CNVsExome sequencing (@Exome_seq) can be used to generate CNV maps bit the data are noisy compared to WGS or SNP-arrays. In this post I’ll describe a novel workflow to get high-quality CNV from an exome-seq pipeline and show some very new data…Image reproduced and enlarged at the bottom of this post. Copy-number is a driving event in cancer and as such we've done lots and lots of copy-number analysis. The majority of this has been on microarrays, which even today offer […]
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2:49 PM | First the Biome, Now the Virome
We've heard much about the gut microbiome. However, have you ever heard of the virome?...
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2:00 PM | Naturopathy vs. Science: Autism
Just when I thought I was out, they pull me back in. My blogging plan was to take a break from my series of naturopathy versus science posts, where I’ve been contrasting the advice from naturopaths against the scientific evidence. From a blogging perspective, naturopathy is a fascinating subject to scrutinize as there is seemingly […]
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2:00 PM | Guest post: Economists should focus on the economy, not public health
Ed note: Please welcome Dr Travis Saunders back for another guest post. Travis Saunders has a PhD in Human Kinetics at the University of Ottawa. His research focuses on the health impact of physical activity and sedentary behaviour. He blogs … Continue reading »The post Guest post: Economists should focus on the economy, not public health appeared first on Public Health.
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1:15 PM | The invasion of well-meaning quacks into West Africa continues apace
Here we go yet again. I’ve been interested in the Ebola outbreak that’s been going on for months in west Africa for a number of reasons. First, it’s a bad disease, and this is the largest outbreak in history. over 5,000 people have died. Second, there’s been a lot of unreasonable fear mongering about the…
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1:04 PM | The risk factor – new evidence on obesity and prostate cancer
The World Cancer Research Fund has published some important new research on prostate cancer and obesity - we explore the findings.
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12:50 PM | Personhood Week: People and Their Pets
It’s Personhood Week here on Only Human. Today’s installment is about people and our fur babies. Monday’s post …
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12:00 PM | Does Your Social Network Shape Your Weight?
According to scientific studies, your wellbeing, your opinions and even your weight are shaped by your social networks. Now many of these factors are broadcast online. How do they affect us? Nicholas Christakis, physician, social scientist and professor at Yale University, has explored how our face-to-face social networks affect everything we think, feel, and do. […]
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8:33 AM | Join the National PR Campaign for ME: Power to the Patient (P2tP)
Have you had enough of all the neglect and abuse of ME/CFS patients?  Gabby Klein says now is the time for a National PR Campaign for ME/CFS to impress a change. Join the Patient Revolution to restore power to ME patients … Thirty years of neglect, incompetence and malfeasance by the Department of Human services (HHS) have rendered ME patients angry, frustrated and disgruntled.  They remain invisible, misunderstood and very sick. Any possible advance in the science of the […]

November 19, 2014

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11:36 PM | Hey vaccine deniers–it’s just simple math
Updated 19 November 2014. When dealing with those pushing pseudoscience, like the antivaccination cult, the most frustrating thing is that they tend to ignore and deny the most basic tenets of science. If denying the fact of gravity would further their goals of “proving” vaccines are neither effective nor safe, they would do so. For […]Continue reading «Hey vaccine deniers–it's just simple math»
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11:00 PM | What does science say about GMO’s–they’re safe
Updated 19 November 2014. The science deniers of the world, whether they deny evolution, global warming, vaccines, or GMO safety, spend their time inventing pseudoscience to support their beliefs and claims. As I have written previously, “Pseudoscience is easy. It doesn’t take work. It’s the lazy man’s (or woman’s) “science.” But it has no value, […]Continue reading «What does science say about GMO's–they're safe»
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10:22 PM | Splash of Cold Water for Clinical Genomics at Cold Spring Harbor Personal Genomes Meeting - Bio-IT World
Splash of Cold Water for Clinical Genomics at Cold Spring Harbor Personal Genomes Meeting - Bio-IT World
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6:43 PM | Ask The Experts: Epilepsy medication used to treat Alzheimer’s
I recently received the following question from a reader based on a prior blog entry on how a medication used to treat epilepsy also helps reverse memory loss with Alzheimer’s disease. You can see the original blog here Question: “I find it a little confusing as to how it is possible that this medication can improve…
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6:41 PM | World Toilet Day: Recommitting to a Clean India
My thoughts on the occasion of World Toilet Day. Let us embrace the spirit of this day and instead of photo-shoots in the name of cleaning India up, try and clean India up for real. Time to put a loo in every house in India!
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