Posts

July 11, 2014

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6:40 AM | Induced pluripotent stem cells in the treatment of retinitis pigmentosa
Researchers at the Columbia University Medical Center (CUMC) have have created a way to develop personalized gene therapies for patients with retinitis pigmentosa (RP), a leading cause of vision loss. The approach, the first of its kind, takes advantage of induced pluripotent stem cells (iPSCs) cell technology to transform skin cells into retinal cells, which are then used as a patient-specific model for disease study and preclinical testing.Using this approach, researchers led by Stephen […]

Li Y, Wu WH, Hsu CW, Nguyen HV, Tsai YT, Chan L, Nagasaki T, Maumenee IH, Yannuzzi LA, Hoang QV & Hua H (2014). Gene Therapy in Patient-specific Stem Cell Lines and a Preclinical Model of Retinitis Pigmentosa With Membrane Frizzled-related Protein Defects., Molecular therapy : the journal of the American Society of Gene Therapy, PMID: http://www.ncbi.nlm.nih.gov/pubmed/24895994

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6:30 AM | Shared decision making in antipsychotic prescribing: the perspective of psychiatrists
Shared decision making is now commonplace, but will this approach ever be fully embraced in relation to antipsychotic prescribing? Liz Hughes reports on a recent qualitative study of consultant psychiatrists' experiences that sheds some light on the issue. The post Shared decision making in antipsychotic prescribing: the perspective of psychiatrists appeared first on The Mental Elf.
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5:51 AM | Samsung incentivises African mHealth project with music
Will also offer discounted handsets and tablets to consumers and health workers
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5:00 AM | Bayesian evidence synthesis and bootstrapping for trial-based economic evaluations: comfortable bed fellows?
By Mohsen Sadatsafavi and Stirling Bryan In economic evaluation of health technologies, evidence synthesis is typically about quantification of the evidence in terms of parameters. Bootstrapping is a non-parametric inferential method in trial-based economic evaluations. On the surface the two paradigms seem incompatible. In a recent paper, we show that a simple and intuitive modification […]
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5:00 AM | NIH Funds Research into Alzheimer’s Disease Genome
Scientists will analyze genome sequence data to identify gene risk, protective factors.
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4:59 AM | Silicone impressions for complete dentures improve patients’ quality of life but increase costs
Yesterday (Dental Elf 10th July 2014) we looked at a trial that compared dentures made with silicone and alginate impression materials. In a study undertaken alongside that trial the authors aimed to assess the cost effectiveness of silicone and alginate impressions for complete dentures. The cost effectiveness analysis (CEA) took the perspective of the UK [read the full story...]
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4:43 AM | Cipla invests £100m in UK
Indian pharma company to fund both commercial and R&D activities
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4:01 AM | These Fruits Were Made for Grilling
Just a few minutes on a grill brings out juices and warms up summer fruit like peaches, apricots and watermelon, which can served simply with a honey and lemon zest, or used in salads and crêpes.
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12:55 AM | Pharma’s shrinking waterhole
A natural metaphor makes us think about our strategy

July 10, 2014

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11:15 PM | UDG buys Galliard and Nyxeon
Will add UK comms firms to Ashfield Healthcare Communications division
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11:00 PM | Baxter reshuffles financial heads
Names CFOs for biotech spin-off and 'new' Baxter
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11:00 PM | Illumina to provide sequencing for UK gene project
Genomics England wants company to sequence genomes of 100,000 NHS patients
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10:54 PM | New study shows drinking alcohol provides no heart health benefit
Results call into question previous studies suggesting one drink per […]
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10:53 PM | Despite setback, ‘Mississippi Baby’ represents significant breakthrough in effort to end AIDS
Statement from the Elizabeth Glaser Pediatric AIDS Foundation In response […]
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10:52 PM | Hubble Spots Spiral Bridge of Young Stars Linking Two Ancient Galaxies
NASA’s Hubble Space Telescope has photographed an unusual structure 100,000 […]
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6:14 PM | Five Inspirational Non-Fiction Books by Physician-Writers You Won’t Want To Put Down
Becoming Dr. Q: My Journey from Migrant Farm Worker to Brain Surgeon   In this spellbinding memoir, Dr. Q, short for Alfredo Quinones-Hinojosa, reveals his tumultuous, yet exciting journey, from his impoverished childhood in Mexico, to literally jumping the fence to enter the United States, to farming tomatoes for pennies under the unforgiving California sun, […]
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5:28 PM | New Parkinson's drug shows promise for 'off' periods
New Parkinson's drug shows promise for 'off' periods 10 July 2014 Finnish pharmaceutical company Biotie have announced promising results showing their new drug 'tozadenant' may help reduce troublesome 'off' periods in Parkinson's. This post has been generated by Page2RSS
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5:27 PM | Living With Cancer: Parting Gifts
Being in a cancer support group eventually means losing a friend.
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1:26 PM | Speeding up data storage by a thousand times with ‘spin current’
A hard drive stores bits in the form of tiny […]
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1:25 PM | Men’s hot flashes: Hypnotic relaxation may ease the discomfort men don’t talk about
Men who experience hot flashes are unlikely to talk much […]
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1:23 PM | New med shows promise in treating eczema
An investigational medication shows promise in treating the most common […]
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1:11 PM | How Twitter can address specific health issues
Childhood obesity is one of the top public health concerns […]
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1:10 PM | Virtual humans inspire patients to open up
When we feel down and find ourselves at the doctor’s […]
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1:09 PM | World Cup Fever: Study Shows Group Fervor Stems from Shared Experiences
The 2014 World Cup has captured the attention of billions […]
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1:06 PM | Amphibians can acquire resistance to deadly fungus
Emerging fungal pathogens pose a greater threat to biodiversity than […]
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1:05 PM | Observing Polar Bears from Space
Monitoring wildlife in the Arctic is difficult. Study areas are […]
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1:04 PM | Lessons Learned from Down Under
At Penn Medicine, we’re fortunate to offer world-class care to our patients, and have facilities that can support groundbreaking research that works to shed light on some of the biggest questions facing medicine today. Often, our faculty and staff are able to take their skills to the far corners of...
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1:00 PM | On the road again
The past 12 months have been quite busy for my wife and I.  In September I defended my PhD at the University of Ottawa/Children’s Hospital of Eastern Ontario.  In December we moved across the country to Halifax so that I …
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12:54 PM | Is a heart attack waiting in your medicine cabinet?
For women taking certain kinds of pain relievers, a heart […]
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12:52 PM | Climate, genetics can affect how long virus-carrying mosquitoes live
It’s just math: The longer a mosquito lives, the better […]
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