Posts

February 26, 2013

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5:59 PM | A Perspective on Psychological Theories of Autism

Clinicians have proposed different psychological theories to explain mental illness from the perspective of the mind. Some of them are imaginative explanations of facts that have not or can’t be [...]

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9:29 AM | Bioinformatician (Smith Lab and Hendrich Lab) Wellcome Trust-Medical Research Coucil Cambridge Stem Cell Institute

The Wellcome Trust – Medical Research Council Stem Cell Institute provides outstanding scientists with the opportunity and resources to undertake ground-breaking research into the fundamental properties of mammalian stem cells. Salary: £24,049-£27,047 A new post has become available to perform bioinformatic analysis of high-throughput data generated by the research teams of Professor Austin Smith and [...]

February 25, 2013

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10:56 AM | Research Fellow Position in Stem Cell Biology on Heart Development in Aberdeen

Research Fellow in Stem Cell Biology WNT signalling in heart development and regeneration An exciting opportunity has arisen for a Research Fellow at the University of Aberdeen. This project focuses on how WNT/β-catenin signalling regulates heart development and cardiomyocyte differentiation. We aim to dissect context-specific roles of WNT signalling at different stages of development and [...]

February 21, 2013

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2:06 PM | Goodbye!

Today was my last day as Community Manager for the Node, so this is goodbye from me! I’ve had a great time these past three years, setting up the site and learning what’s of interest to the developmental biology community. My favourite part of the job was meeting people in person at conferences and lab [...]

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7:00 AM | myIDP (Individual Development Plan) by Science Careers

The myIDP (Individual Development Plan) is career aptitude test and career planning site for scientists developed by Science Careers. I recently changed careers, starting my own scientific writing company after a postdoc in developmental biology, so I was interested to see how the software worked. The first thing you do is go through a few [...]

February 20, 2013

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12:10 PM | Breakthrough Prize floors winners with sheer amount of money

Eleven biologists received some unbelievable news this week: They will each receive 3 MILLION dollars from a newly established award. The Breakthrough Prize was founded by Mark Zuckerberg (Facebook) , Sergey Brin (Google) and venture capitalist Yuri Milner, with the goal of supporting research into life extension and curing diseases. Among the eleven winners are [...]

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10:00 AM | Image competition: stem cells

In a journal like Development, full of beautiful immunofluorescence images of developing tissues and organisms, it’s quite rare that a picture of stem cells stands out from an aesthetic point of view. Cells growing in a dish just aren’t quite as pretty as multicolour embryos or organs. At least, that’s the impression that we get [...]

February 19, 2013

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2:38 PM | Mouse Molecular Genetics: Save the date 18-21 September 2013

We are pleased to announce that the 26th annual Mouse Molecular Genetics meeting will be held at the Wellcome Trust Genome Campus, from 18 to 21 September 2013. This meeting is a leading forum for researchers who apply genetics and genomics techniques to address fundamental issues in mammalian biology, including stem cell biology, development, epigenetics [...]

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12:30 PM | Cover winner: mouse confocal

We have a winner! This colourful image quickly took the lead, and stayed there. It will appear on the cover of Development soon. This confocal image (extended focus Z stack) of an E10.5 day mouse embryo was taken by Joyce Pieretti (University of Chicago), Manuela Truebano (Plymouth University), Saori Tani (Kobe University) and Daniela Di [...]

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12:33 AM | Good News!!!!

Unless you live in the United States, Suriname, Liberia, Tonga, Western Samoa, Papua New Guinea, or Palau...

February 18, 2013

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8:18 PM | Things that look like Xenopus

Have you ever thought to yourself ‘Hey, that inanimate object looks just like a xenopus!’ No? Well maybe after reading this you will. I started a PhD in a Xenopus lab in 2010 and ever since I’ve been seeing Xenopus everywhere. So much so that I decided to set up a facebook page called ‘Things that [...]

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5:18 AM | The UCL-Tohoku University joint Symposium is coming soon!

Dear developmental biologists and neurobiologists, I’d like to give you some information on the UCL-Tohoku University joint Symposium from 21st to 22nd Feburary. If you are interested in research fields from cell/developmental biology to Neuroscience, you are free to join it.

February 15, 2013

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3:47 PM | Stem cell decisions and the cell cycle

A lot of things cycle in life, even down to the cellular level. In the developing central nervous system, regulators of the cell cycle play important roles in maintaining the balance between stem cell self-renewal and differentiation. A recent paper in the journal Development describes a cell cycle regulator in stem and progenitor cells in [...]

Liang, H., Xiao, G., Yin, H., Hippenmeyer, S., Horowitz, J. & Ghashghaei, H. (2013). Neural development is dependent on the function of specificity protein 2 in cell cycle progression, Development, 140 (3) 552-561. DOI: 10.1242/dev.085621

Citation

February 12, 2013

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3:18 PM | Marsupials are a missing link in vertebrate development

Marsupials were popular models for early development in the early 1900s , with classic morphological studies performed by notable embryologists such as J.P. Hill, C.G. Hartman, T.T. Flynn (Errol Flynn’s father) and E. McCrady. These workers were fascinated by the marsupial mode of blastocyst formation, which contrasts starkly with that of eutherians. One key difference [...]

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1:00 PM | In Development this week (Vol. 140, Issue 5)

Here are the research highlights from the current issue of Development: Evolution of mesoderm induction Fibroblast growth factors (FGFs) are essential for mesoderm induction in vertebrates and for early mesoderm formation in invertebrate chordates. However, functional studies to date do not support a role for FGF signalling in mesoderm induction in other deuterostomes (animals [...]

February 07, 2013

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4:36 PM | Review: Electric shock

Last year, Matter launched, after a successful Kickstarter campaign, as a magazine that publishes only long, well-written articles related to “science, technology and the ideas shaping our future”. Each issue is one article, which costs $0.99 to access. (On my iPad, they ‘re categorized as books, and are each about 40 pages long, which I [...]

Tseng A. & Levin M. (2013). Cracking the bioelectric code: Probing endogenous ionic controls of pattern formation, Communicative & Integrative Biology, 6 (1) e22595. DOI: 10.4161/cib.22595

Tseng A.S., Beane W.S., Lemire J.M., Masi A. & Levin M. (2010). Induction of Vertebrate Regeneration by a Transient Sodium Current, Journal of Neuroscience, 30 (39) 13192-13200. DOI: 10.1523/JNEUROSCI.3315-10.2010

Beane W.S., Morokuma J., Lemire J.M. & Levin M. (2013). Bioelectric signaling regulates head and organ size during planarian regeneration, Development, 140 (2) 313-322. DOI: 10.1242/dev.086900

Pai V.P., Aw S., Shomrat T., Lemire J.M. & Levin M. (2012). Transmembrane voltage potential controls embryonic eye patterning in Xenopus laevis, Development, 139 (2) 313-323. DOI: 10.1242/dev.073759

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February 04, 2013

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4:42 PM | Human Breast Milk Contains PLURIPOTENT Stem Cells!

Last September, during the Bi-Annual Meeting of the International […]

February 01, 2013

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11:00 AM | Science Online Conference

The annual Science Online conference is currently underway in North Carolina. It attracts mainly scientists and science writers who use the internet to advance science communication. Everyone at the conference is extremely Twitter-savvy, and it’s impossible to keep up with the #scio13 hashtag, but I’ve created a Storify below that includes some of the tweets [...]

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12:34 AM | Retroviruses for Axolotl Research

Many salamanders can regenerate limbs, and even a seven-year-old child appreciates exactly the reasons why this feat is so remarkable. How can an animal that has been living its life, using its leg full of muscles and bones and tendons and nerves every single day, suddenly grow a new one at some random time? When [...]

January 31, 2013

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5:21 PM | This month on the Node – January 2013

Let’s start this monthly summary with two fantastic posts that were left out of last month’s roundup due to the holiday period (and scheduled posts). Idoia Quintana studies shark brain development in Spain, and travelled to Scotland recently to learn how to work with mouse brains, so she could do some cross-species comparison. “At the [...]

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12:47 PM | Post-doc position in evolution and development in Paris

A two-year post-doctoral positionis available in the group of Guillaume Balavoine and Michel Vervoort (http://www.ijm.fr/en/ijm/research/research-groups/metazoaires/) at the Institut Jacques Monod (IJM) in Paris (France). The IJM is a leading French biological research institute, comprising about 25 interactive research groups and high-quality technological facilities, including a cutting-edge imaging platform. The primary research focus of the group is to [...]

January 30, 2013

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2:53 PM | Vote for a Development cover – Woods Hole 2012 class round 1

Each year, students of the Woods Hole Embryology course produce some amazing images. Last year, readers of the Node selected four images from the 2011 course to appear on the cover of Development. Now it’s time to do the same with the images from the 2012 course. Here’s the first batch of [...]

January 29, 2013

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1:09 PM | In Development this week (Vol. 140, Issue 4)

Here are the highlights from the current issue of Development: Pancreatic injury unlocks cell potential Identifying methods by which pancreatic β-cells can be produced is of major therapeutic importance. Whether there are adult pancreatic cells with the potential to make new β-cells is a matter of much debate. During embryonic development, the transcription factor [...]

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9:13 AM | Stem cells at school, plus new fact sheets on EuroStemCell

Happy 2013 everyone! I hope you’re all settling into the year nicely.We sent out our EuroStemCell January newsletter last week and I thought some of you might be interested in our latest schools activities and fact sheets on stem cell research. Highlights this month include a new lesson for 12-14 year olds on Stem cell [...]

January 28, 2013

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12:20 PM | Woods Hole course application deadline extended

The Woods Hole image voting posts are some of the most popular posts on the Node (and yes, there will be a new one up VERY soon!). These images are all made by students of the Woods Hole Embryology course, and you still have a chance to be part of the 2013 class! The application [...]

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2:32 AM | Microinjection of preimplantation mouse embryos

Hello, my name is Stephanie and I’m a graduate student in Dr. Amy Ralston’s lab at the University of California Santa Cruz. I just returned from a trip to Dr. Yojiro Yamanaka’s lab at McGill University in Montreal, Quebec. This trip was funded by the Development Travelling Fellowship from Company of Biologists. I highly recommend checking [...]

January 17, 2013

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5:58 PM | PhD opportunity available in Dundee

O-GlcNAc signalling during embryonic stem cell differentiation My lab is studying the signalling mechanisms governing the onset of differentiation of pluripotent embryonic stem (ES) cells. Work from this and other labs (e.g. 1, 2) has revealed a critical role for autocrine FGF signalling and consequent sustained phosphorylation of the kinase Erk during the differentiation process. [...]

January 16, 2013

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5:49 PM | http://feedproxy.google.com/~r/the_Node/~3/2azNyArykJQ/

PhD position in the UK for a Developmental Geneticist PhD project title: Non-genetic mechanisms of inheritance influenced by the maternal environment Project description: In the last few decades, it has been becoming increasingly clear that organisms can express phenotypes that are inherited in a non-Mendelian fashion. Studies in humans, for example, show [...]

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5:49 PM | PhD position in the UK for a Developmental Geneticist

PhD project title: Non-genetic mechanisms of inheritance influenced by the maternal environment Project description: In the last few decades, it has been becoming increasingly clear that organisms can express phenotypes that are inherited in a non-Mendelian fashion. Studies in humans, for example, show that grandfathers who experienced dramatic diet fluctuations as children influenced the incidence [...]

January 15, 2013

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4:37 AM | Early mouse development seen in real time

Developmental biologists have long relied on the power of observation to understand how embryos develop. In addition, pharmacologic and genetic manipulation of embryos gives us clues as to the mechanisms involved in proper developmental processes. The ability to combine embryo manipulation with observation of embryonic development in real time has been possible for quite some [...]

Massarwa R. & Niswander L. (2012). In toto live imaging of mouse morphogenesis and new insights into neural tube closure, Development, 140 (1) 226-236. DOI: 10.1242/dev.085001

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February 26, 2013

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