Posts

October 08, 2014

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9:00 AM | Landscapes of Ladakh (1)
  Recently we undertook some work in Ladakh (India), amongst some beautiful landscapes. To see and learn more – why not come to this event at The Geological Society. Photos: Geology for Global Development (2014)

October 07, 2014

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11:58 AM | In Development this week (Vol. 141, Issue 20)
Here are the highlights from the current issue of Development:   Small (molecule) steps to making bone The repair of cartilage and bone following damage remains a clinical challenge. Current cell-based therapies rely mostly on adult mesenchymal stromal cells, but the expansion of these into correctly differentiated and functionally competent chondrocytes, which give rise to […]

October 06, 2014

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12:01 PM | THE ROLE OF THE KETOGENIC DIET IN AUTISM OR WHY BACON IS YOUR FRIEND PART 1: HISTORICAL BACKGROUND
Shortly after my grandson was born it became evident that he was suffering from relentless seizures. Although something was definitely wrong to us his primary physicians believed that we were […]
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8:56 AM | Event: The Lost World of Ladakh: Reclaiming the Past, Sustaining the Future
THE LOST WORLD OF LADAKH: RECLAIMING THE PAST, SUSTAINING THE FUTURE Venue: The Geological Society, Burlington House, Piccadilly, London W1J 0BG. 24 October 2014, 5.30pm – 8.30pm  www.geolsoc.org.uk/Lost-world-of-Ladakh The Geological Society recently co-organised an international conference in Leh, the capital of the historic Himalayan kingdom of Ladakh. Sustainable Resource Development in the Himalayas brought together scientists from […]

October 03, 2014

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10:46 PM | Tough decisions for the developing brain
To form complex organs, somatic stem cells proliferate and then differentiate during development. In this process, intrinsic factors, i.e. the sequential expression of transcriptional genes, and extrinsic factors, i.e. extracellular microenvironment, are intimately involved. Recent in vitro studies have revealed that the physical properties of the extracellular niche, possibly tissue stiffness, may play an important […]
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5:21 PM | Pregnant women’s immune systems overreact to the flu
A new study offers an exception to the assumption that a pregnant woman’s immune system fades to keep from attacking the growing fetus.
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2:03 PM | ‘From Stem Cells to Human Development’ – A Company of Biologists’ Workshop
Last week, several of the Company of Biologists’ team de-camped to Surrey for our latest Workshop ‘From Stem Cells to Human Development’. Unlike previous events, this was a larger meeting, with 112 participants from all over the world. Organised by the editors of Development, the theme of the meeting (as implied by the title!) was […]
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12:26 PM | A Graphic on Vaccines and Autism
I recently received a request to post a graphic on vaccines and autism on my blog. The same came from Healthcare Management Degree Guide (http://www.healthcare-management-degree.net/). The request was made by […]

October 02, 2014

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10:37 AM | What do sperm have to do with brain tumors?
  This post was originally published in the Knoepfler Lab Stem Cell Blog.      Sometimes in science there are unexpected threads tying seemingly very different things together. Unraveling the knots in these threads can lead to new insights into important developmental processes and mechanisms of disease. My lab studies epigenomic and transcription factors including […]

Yuen, B., Bush, K., Barrilleaux, B., Cotterman, R. & Knoepfler, P. (2014). Histone H3.3 regulates dynamic chromatin states during spermatogenesis, Development, 141 (18) 3483-3494. DOI: 10.1242/dev.106450

Citation

October 01, 2014

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1:24 PM | This month on the Node- September 2014
Here are some of the highlights for September:   Research: - Sylvain discussed his recent Development paper on the tristable regulatory network behind cell fate decisions in the early embryo. - Aryeh wrote about his research on spontaneous patterning of human ES cells, recently published in Nature Methods (he is also hiring a postdoc!). - and Christelle highlighted a recent […]
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12:27 PM | Cómo seguir la creciente tasa de prevalencia del autismo?
Desde el 1988 la Organización Mundial de la Salud en colaboración con el Centro para la Investigación sobre la Epidemiología de Desastres ha mantenido una base de datos (EM-DAT) sobre […]
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2:07 AM | The Future of Research Symposium:The Funding of Research
This is the last of four posts relating to the Future of Research symposium which was announced in a previous blog post. Each of these posts will discuss a topic that is the focus of a workshop at the Symposium. Even if you can’t attend, please tweet @FORsymp with suggestions, or follow us to respond […]

September 30, 2014

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8:57 PM | “Smells Like Development” – The 73rd Society for Developmental Biology Meeting
Hosted in beautiful Seattle, the Society for Developmental Biology (SDB) held its 73rd Annual Meeting on the University of Washington campus in (mostly) sunny July. Here researchers from around the world working on different developmental processes and models come together to share their results and learn about advances in the field. SDB is quite generous […]
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12:47 AM | USA Tenure Track Faculty Position, University of Chicago, Department of Neurobiology
The University of Chicago’s Department of Neurobiology seeks to recruit tenure-track faculty. Appointments can be made at any rank from Assistant Professor to Professor, and in any area of neurobiology. Candidates must have a doctoral degree and at least two years of postdoctoral training. Researchers in molecular/cellular neurobiology or neural development/plasticity are particularly encouraged to apply. […]

September 29, 2014

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11:54 AM | The National Database for Autism Research (NDAR): Playing Favorites in Autism Research
According to their web site (http://ndar.nih.gov/): “The National Database for Autism Research (NDAR) is an NIH-funded research data repository that aims to accelerate progress in autism spectrum disorders (ASD) research […]

September 28, 2014

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11:37 PM | The Future of Research Symposium:Metrics: The Folly of Hoping for X whilst Rewarding Y
This is the third of four posts relating to the Future of Research symposium which was announced in a previous blog post. Each of these posts will discuss a topic that is the focus of a workshop at the Symposium. Even if you can’t attend, please tweet @FORsymp with suggestions, or follow us to respond […]

September 26, 2014

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9:30 AM | Friday Photo (129) – Annual Conference
  GfGD Annual Conference 2014 A selection of photographs taken from the GfGD Annual Conference, hosted and supported by the Geological Society of London. The event focused on the skills required to make a long-term, effective contribution to international development. (Credit: Geology for Global Development, 2014)
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7:56 AM | Post-doc position in Plant Developmental Cell Biology
No summary available for this post.

September 25, 2014

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8:07 PM | The Future of Research Symposium:The Structure of the Workforce
This is the second of four posts relating to the Future of Research symposium which was announced in a previous blog post. Each of these posts will discuss a topic that is the focus of a workshop at the Symposium. Even if you can’t attend, please tweet @FORsymp with suggestions, or follow us to respond […]
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2:21 PM | Faculty Position in Developmental Biology, Department of Biological Sciences, Purdue University
We invite applicants for a tenure-track faculty position in Developmental Biology. We welcome colleagues whose research activities will complement our existing focus areas in neurosensory systems, neurodegeneration, cancer and other diseases, epigenetics or pathogenesis. Potential model systems of interest are mouse, zebrafish, fruit fly or stem cells to study development and disease. The successful applicant […]

September 24, 2014

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9:08 PM | The debate over spanking is short on science, high on emotion
Spanking to discipline a child sparks heated debate that reflects deep divides in our society. Studies generally show negative effects of spanking, but there are many caveats.
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4:59 PM | Postdoctoral postions in Systems Stem Cell Biology
Postdoctoral positions are available in the laboratory of Systems Stem Cell and Developmental Biology (PI Aryeh Warmflash) at Rice University (Lab website) . We use human embryonic stem cells as a model for studying cellular communication, self-organization, and spatial patterning during embryonic development. The lab utilizes a combination of quantitative experimental techniques and mathematical modeling to address fundamental […]
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4:48 PM | Towards a synthetic embryo
Waddington, whose writings on the epigenetic landscape continue to influence developmental biology to this day, called the developing embryo “the most intriguing object that nature has to offer”(Waddington, 1966). The mechanisms of pattern formation and morphogenesis have fascinated biologists for centuries. One question that is difficult to answer is what are the minimal requirements for […]
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12:11 PM | La llamada inflamación del autismo
Este año he podido asistir a un gran número de congresos en diversas partes del mundo. Una cosa que me ha llamado la atención es la forma en que algunos […]

September 23, 2014

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5:15 PM | The Future of Research Symposium:How Scientists are Trained
This is the first of four posts relating to the Future of Research symposium which was announced in a previous blog post. Each of these posts will discuss a topic that is the focus of a workshop at the Symposium. Even if you can’t attend, please tweet @FORsymp with suggestions, or follow us to respond […]
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3:01 PM | When real life becomes equations: Control of Epiblast and Primitive Endoderm specification during mouse preimplantation development.
During mouse preimplantation development, the zygote divides and forms three distinct lineages: one embryonic called the Epiblast (Epi) and two extraembryonic called trophectoderm (TE) and Primitive Endoderm (PrE). The first cell fate decision occurs at the morula stage (from 16-cell to 32-cell) between TE and the Inner Cell Mass (ICM) and the second cell fate […]
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2:17 PM | In Development this week (Vol. 141, Issue 19)
Here are the highlights from the current issue of Development:   Modelling fate decisions in the early mouse embryo In the early embryo, the first fate decision separates the trophectoderm from the inner cell mass (ICM). Subsequently, the ICM segregates into epiblast (Epi) and primitive endoderm (PrE), but how do cells decide which of these […]
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10:06 AM | Guest Blog: Reflections on the Students’ Education Program, Ladakh, June 2014
Celia Willoughby is an undergraduate geography student at University College London. In June 2014 she joined the GfGD team in Ladakh (India) to support the ‘Sustainable Resource Development in the Himalayas’ work – focusing on the hazards education course. Here she shares her reflections on the experience… Ladakh is a beautiful and remote region in […]

September 22, 2014

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3:21 PM | I left my frog in San Francisco:The 15th International Xenopus ConferenceAsilomar CA, 2014
Every two years, the international Xenopus community gathers to meet. Two years ago I wrote about the meeting in Toulon, France and this time we crossed the pond to Asilomar, CA, just south of San Francisco. Cat Vicente recently wrote about Asilomar in the context of conference venues whilst attending the Genetics Society of America […]
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2:58 PM | International Research Conference on Science, Health and Medicine 2014 (IRCSHM 2014)
[Apologies for cross-postings!] Call for Papers – IRCSHM 2014 October 15-16, Dubai, UAE Dear Colleague, The unique idea behind International Research Conference on Science, Health and Medicine 2014 (IRCSHM 2014) is to provide an opportunity for leading academicians, scientists, researchers, doctors, medical practitioners, paramedical specialists and industry professionals from around the world to network and […]
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