Posts

December 11, 2012

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9:49 AM | Nobel Laureates Warn Against Going over the Fiscal Cliff

Although I’m not a fan of simply reposting press releases, this press release from The Coalition for the Life Sciences, about a letter-campaign by Nobel Laureates to emphasize the importance of research funding, is worthy of a read. The coalition is made up of several scientific organisations that overlap with the Node’s readership (ASBMB, ASCB, [...]

December 06, 2012

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3:03 PM | Book review: Everything you always wanted to know about auxin but were afraid to ask

This book review originally appeared in Development. Sabrina Sabatini reviews “Auxin Signaling: From Synthesis to Systems Biology ” (Edited by Mark Estelle, Dolf Weijers, Karin Ljung and Ottoline Leyser). Book info: Auxin Signaling: From Synthesis to Systems Biology. Edited by Mark Estelle, Dolf Weijers, Karin Ljung, Ottoline Leyser. Cold Spring Harbor Laboratory Press (2011) 253 [...]

December 04, 2012

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5:02 PM | Reprogramming development

This editorial by Development Editor-in-Chief Olivier Pourquié appears in the current issue of Development. It seems most appropriate to start this editorial by congratulating the 2012 winners of the Nobel prize, John Gurdon and Shinya Yamanaka, for their work on stem cells and reprogramming. We at Development are particularly proud of this prize as John [...]

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2:17 PM | In Development this week (Vol. 140, Issue 1)

Here are the highlights from the current issue of Development: Gut feeling about Wnt doses The intestinal epithelium continuously renews throughout life. Canonical Wnt signalling – a major player in this renewal – both controls intestinal epithelial proliferation and maintains intestinal stem cells. The existence of a gradient of β-catenin expression along the colonic [...]

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7:21 AM | EVODEVO WIKI EDIT EVENT.

EVODEVO WIKIPAEDIA EDIT-ATHON. Friday December 7th 2012 a the Department of Zoology, South Parks Road, University of Oxford We are spending a day editing and updating EVODEVO related pages on Wikipaedia. If you would like to join us contact peter.holland@zoo.ox.ac.uk or aziz.aboobaker@zoo.ox.ac.uk We will start about 10.30 am and two official trainers from Wikimedia UK [...]

November 30, 2012

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4:53 PM | This month on the Node – November 2012

Site upgrade We now have a “featured topics” bar across the top of the page, which has the same function as these highlight posts: to let you know what happened on the Node recently. This upgrade also came with author profile page. Do remember to fill out your profile bio, because people can now see [...]

November 29, 2012

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2:29 PM | Book review: An introduction to decoding genomes

This book review originally appeared in Development. Jennifer Mitchell reviews “Introduction to Genomics” (by Arthur M. Lesk). Book info: Introduction to Genomics By Arthur M. Lesk. Oxford University Press (2011) 424 pages ISBN 978-0-19-956435-4 £34.99 (paperback) The past 20 years has seen a revolution in genomics. From the completion of the human genome in 2003, [...]

November 27, 2012

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2:13 PM | Mammalian epigenetics in biology and medicine – NEW from Royal Society Publishing

Royal Society Publishing has just published Mammalian epigenetics in biology and medicine, compiled and edited by Fumitoshi Ishino,Yoichi Shinkai and Emma Whitelaw. See - http://bit.ly/RGO3Y0 for further details or you can go straight to the issue contents at http://rstb.royalsocietypublishing.org/content/368/1609.toc The issue (and ALL Royal Society content) is currently freely available to access online until 29th [...]

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2:08 PM | The BSCB Science Writing Competition- time to start writing!

Have you got a great science story in you? This autumn, the BSCB is again running its Science Writing Competition! The judges are looking for interesting, enthusiastic articles covering topics of key relevance in biomedical science- this can mean a piece on research but also other topics relevant to cell biology, such as science policy [...]

November 26, 2012

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10:22 AM | Featured posts and author pages

Notice something different on the Node today? We now have a bar at the top to feature particular posts. It will be updated by Node admins, who select posts to appear here. (N.B. If you see text but not in neat little boxes, your browser still remembers the old design. Refresh page and/or clear cache [...]

November 23, 2012

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12:49 PM | Post-Doctoral Research Associate position at University College London

Post-Doctoral Research Associate position at University College London Cancer Institute The group is based at the Cancer Institute at UCL and works on modelling inherited and acquired haematopoietic diseases using the zebrafish. The goal is to generate relevant models to study the genetics of these disorders and perform chemical screens to identify novel therapeutic targets [...]

November 21, 2012

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2:24 PM | Postdoctoral Positions

POSTDOCTORAL POSITIONS are available to study different aspects of mammalian organogenesis, with a particular focus on the cellular and molecular mechanisms controlling the development of the visual system and the lymphatic vasculature using available mouse models. Highly motivated individuals who recently obtained a PhD or MD degree and have a strong background in molecular, cancer [...]

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2:24 PM | http://feedproxy.google.com/~r/the_Node/~3/3S4Ou2EJRNg/

Postdoctoral Positions POSTDOCTORAL POSITIONS are available to study different aspects of mammalian organogenesis, with a particular focus on the cellular and molecular mechanisms controlling the development of the visual system and the lymphatic vasculature using available mouse models. Highly motivated individuals who recently obtained a PhD or MD degree and have a strong background in [...]

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12:09 PM | In Development this week (Vol. 139, Issue 24)

Here are the highlights from the current issue of Development: Translating Apc1 loss into intestinal proliferation Most colorectal cancers carry inactivating mutations in adenomatous polyposis coli (APC), a negative regulator of Wnt signalling. Moreover, in mice, Apc inactivation is sufficient to drive intestinal hyperplasia. Now, Julia Cordero, Owen Sansom and colleagues use the adult [...]

November 20, 2012

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5:25 PM | SpotOn London

Last week I attended SpotOn London – a conference focused entirely on the role of the Internet on research, science outreach, science policy, tools, and related topics. There were talks about using alternative metrics to asses the value of research papers, discussions about doing outreach while working in the lab, issues related to women in [...]

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5:11 PM | Post-doctoral position available: Neural crest development in Xenopus

SCHOOL OF BIOLOGICAL SCIENCES, UNIVERSITY OF EAST ANGLIA POST DOCTORAL RESEARCH ASSOCIATE POSITION AVAILABLE Neural Crest Development in Xenopus £30,122 to £35,938 per annum A Post Doctoral Research Associate position to investigate the Regulation of Neural Crest development by transcriptional pausing is available in the lab of Dr. Grant Wheeler, School [...]

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5:07 PM | PhD position available: The role of microRNAs in neural crest development

SCHOOL OF BIOLOGICAL SCIENCES, UNIVERSITY OF EAST ANGLIA PhD POSITION AVAILABLE The role of microRNAs in neural crest development MicroRNAs (miR) are short, non-coding RNAs around 22 nucleotides long. They block gene expression either by translational repression or by causing the degradation of the mRNAs they bind to. They are involved in [...]

November 19, 2012

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2:29 PM | Advent and site updates

Advent calendar Thanks to everyone who has sent in suggestions for papers for the advent calendar. We’re still looking for a few more to take us to a complete set of 24, so if you read something really great that was published after December 2011, please let us know via email. We’ll need your submissions [...]

November 14, 2012

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3:30 PM | Farish A. Jenkins, Jr (1940-2012)

On the morning of Sunday, November 11th, the world lost a great gentleman scholar - Professor Farish A. Jenkins, Jr of the Museum of Comparative Zoology, Harvard University. Farish was an anachronism in today’s world who would have relished in lengthy discourse with the great comparative anatomists of the mid 19th century, [...]

November 13, 2012

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9:10 PM | Remember this: Sox1 marks neural stem cells in the hippocampus

Most folks think that our brains don’t produce any more neurons after we’re born, but thankfully they do! A small subset of stem cells within the hippocampus gives rise to neurons in a region of the brain believed to be associated with learning and memory, and a recent paper describes the self-renewal properties and potential [...]

November 10, 2012

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5:09 PM | Post-doctoral position in muscle-type specific genomic approaches

Identifying gene expression signatures that underlay diversification of muscle cells using cell type specific genomic approaches in Drosophila Muscle network in Drosophila embryos represents an attractive system for studying cell diversification. Each muscle displays a specific size, location, attachment points and innervation. Several studies including those of our group (Junion et al., 2007, Bataillé [...]

November 08, 2012

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2:35 PM | Favourite papers advent calendar

What was your favourite paper in the fields of developmental or stem cell biology this past year? We’re preparing a little feature on the Node for the month of December: an advent calendar with a new paper recommendation each day from December 1 to 24. For this, we need your help! What was your favourite [...]

November 06, 2012

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2:55 PM | Editorial opportunities at the Company of Biologists

Here at Development, and at our sister journal Disease Models and Mechanisms, we are currently advertising two editorial positions. Within the Development team, we are seeking to recruit a new Associate Reviews Editor with special responsibility for the stem cell field - reflecting the journal’s increasing visibility in that area. Further details on this exciting [...]

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1:36 PM | Scientific Editor Disease Models and Mechanisms

Scientific Editor Disease Models & Mechanisms Based in Cambridge, UK Joining a young journal in an expanding and important area of research, this is an exciting opportunity for a promising scientific editor to make a significant contribution to a growing open access journal serving a major new biomedical community. The journal is entering the next [...]

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1:29 PM | New Reviews Editor at Development

Associate Reviews Editor (Stem Cells) Development Based in Cambridge, UK Applications are sought for a new role of Associate Reviews Editor for the stem cell field at Development. Joining an experienced, expanding and successful team, this is an exciting opportunity for a promising scientific editor to make a significant contribution to one of the major [...]

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12:01 PM | In Development this week (Vol. 139, Issue 23)

Here are the highlights from the current issue of Development: Dishevelled: the Notch-Wnt go-between The Notch and Wnt signalling pathways are used during animal development to generate a diverse array of cell types. The two pathways often have opposing effects on cell-fate decisions but some cells receive inputs from both pathways simultaneously. In these [...]

November 05, 2012

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11:22 PM | Gene regulation and developmental biology at the Royal Society

Last week, the Royal Society hosted a meeting entitled “Regulation from a distance: Long-range control of gene expression in development and disease”. The impressive London offices of the Society (complete with double helix-inspired door handles) added a sense of occasion to what was bound to be a fascinating meeting, based on the list of excellent [...]

November 01, 2012

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5:07 PM | This month on the Node – October 2012

The big news this past month was of course the announcement of the Nobel Prize for Physiology and Medicine, awarded to John Gurdon and Shinya Yamanaka for their work on cellular reprogramming. Katherine Brown wrote a brief post about John Gurdon’s connection to the Company of Biologists – and to the Node! Hydra Summer School [...]

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4:58 PM | Celebrating stem cells

Last month was an exciting one for stem cell research. I’m sure you all saw how stem cells hit international headlines with the announcement of a Nobel Prize for John B. Gurdon and Shinya Yamanaka. I thought you might be interested to read reactions from several leading scientists and check out a film clip about [...]

October 30, 2012

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5:25 PM | Development symposium photos and panel discussion

Last Thursday, Development organized a one-day symposium, “Past, Present and Future”, to mark the 25th anniversary of the journal. All speakers were past or present editors of Development, and the work they presented gave a broad overview of the current status of the field. At the end of the day, a panel discussion looked back [...]