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In a new study, a collaborative team of researchers from Inserm, CNRS and MDC have discovered a previously unknown ability that hematopoietic stem cells (HSCs) have. According to the study, HSCs can recognise when the body experiences certain stress conditions, like infection or inflammation, and respond accordingly by producing the type of cell that is in highest demand. The study may one day help patients who need a hematopoietic stem cell transplant to recover faster.Read More
Noushine Mossadegh-Keller, Sandrine Sarrazin, Prashanth K. Kandalla, Leon Espinosa, E. Richard Stanley, Stephen L. Nutt, Jordan Moore & Michael H. Sieweke (2013). M-CSF instructs myeloid lineage fate in single haematopoietic stem cells, Nature, Other: 10.1038/nature12026
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Researchers from the University of Michigan (U-M) just reported that after 15 years of experimentation on mice, they discovered that autophagy is essential in keeping neural stem cells (NSCs ) alive and ready to replenish any damaged brain and neural cells.Read More
Wang C, Liang CC, Bian ZC, Zhu Y & Guan JL (2013). FIP200 is required for maintenance and differentiation of postnatal neural stem cells., Nature neuroscience, PMID: 23542691
Jun-Lin Guan, Anna Katharina Simon, Mark Prescott, Javier A. Menendez, Fei Liu, Fen Wang, Chenran Wang, Ernst Wolvetang, Alejandro Vazquez-Martin & Jue Zhang & (2013). Autophagy in stem cells, Autophagy, Other: Link
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We are saddened to learn that IVF pioneer Professor Sir Bob Edwards has died at the age of 87, following a long illness. The University of Cambridge announced his death earlier today, noting that through his work Professor Edwards had … Continue reading →
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If Speaking of Research was a person in the US, entering its sixth year of life, they should have received vaccines for the following: chickenpox, diphtheria, Hib, HepA, HepB, flu, measles, mumps, pertussis (Whooping Cough), polio, pneumococcal, rotavirus, rubella and tetanus … Continue reading →
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Overweight and obese women are more likely to require specialist medical care during their pregnancy due to the increased risk of adverse neonatal and maternal outcomes, finds a new study published today (27 March) in BJOG: An International Journal of Obstetrics and Gynaecology. The study, carried out by a team from Queen’s University Belfast and … Continue reading »
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Recently, a team of researchers from INSERM* and CEA** released a study in which they discovered, in a mouse model, that the pharmacological inhibition of the transforming growth factor beta (TGF-β) improves the production of new neurons. These findings could help alleviate cognitive decline in elder people and treat cerebral lesions caused by radiation therapy.Read More
Pineda JR, Daynac M, Chicheportiche A, Cebrian-Silla A, Sii Felice K, Garcia-Verdugo JM, Boussin FD & Mouthon MA (2013). Vascular-derived TGF-β increases in the stem cell niche and perturbs neurogenesis during aging and following irradiation in the adult mouse brain., EMBO molecular medicine, 5 (4) 548-62. PMID: 23526803
