Posts

April 19, 2015

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8:53 PM | Flakka in Meme
The latest media hysteria I've seen about Flakka includes a man who believed he was God, had sexual relations with a tree, and assaulted a law enforcement officer.All of these recent Flakka headlines are reminiscent of the MDPV-zombie days of 2010-2013. I figured we could combat some of this recent silliness in media reports with some silliness of our own.Who fed these puppies some Flakka?Here's Johnny! On Flakka. Looking back at the Shining, it makes a little more sense...Wonder if […]
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3:37 PM | “Reynold’s number” (Re) describes the ratio...
High Reynold's number (~3900) from large eddy simulation: no laminar flow http://www6.miami.edu/acfdlab/CFD.html“Reynold’s number” (Re) describes the ratio between forces of inertia and viscosity in discussions of fluid mechanics. Re = (V·d·ρ) / μ As shown in the formula above, Reynold’s number scales this ratio of density (ρ) to viscosity (μ) by speed of flow through (V), and diameter (d) of the fluid container (e.g. a pipe). These factors […]
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2:00 PM | The Romance of Chemistry
We’ve spent the past week looking at Moore’s law, its history, implications, and what it might look like in the future. But today, on the 50th anniversary of the publication of his landmark paper, we want to consider the making of Moore the man. The following excerpt is taken from Moore’s Law: The Life of Gordon Moore, Silicon Valley’s Quiet Revolutionary, due for publication by Basic Books on May 5 and coauthored by Arnold Thackray, CHF’s chancellor and founding […]
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1:31 PM | The Artist’s License – revoked (again)!
Alice Dreger (@AliceDreger) wrote a book. David Dobbs (@David_Dobbs) reviewed it in The New York Times. Klaas Verplancke (@klaasics) drew a picture to illustrate the review. Here is that picture. (I use it here without permission, but hope that everyone can be reasonable about my reproduction – please). Now that I have familiarized myself with […]
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1:01 PM | Science Media Centre and e-cigarettes
As I noted in a brief post yesterday, e-cigarette regulation is an important issue on which both the medical establishment and life science researchers have called for caution, yet their voices are not being reflected in media coverage of the issue. I also recapped yesterday on how, as the author of the Cochrane review, Professor Peter Hajek at Queen Mary’s University, London (QMUL) wrote that e-cigarettes were “unlikely to cause harm” with no citation to support the claim, […]
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8:57 AM | This Week in Chemistry – Vodka & Chromatography, & Detecting Decaying Meat
Here’s the weekly summary of both new chemistry research and studies that have been in the news. This week features a potential explanation for the energy source for the dynamo that powers Earth’s magnetic field, how the household sponge could help fight BPA contamination in industrial waste water, and more. As always, links to further articles and original […]
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7:00 AM | Scientist of the Week 5: Elsie Widdowson
This weeks #SOTW is Elsie Widdowson CBE CH FRS. The well-known British chemist and dietitian. Famous for her research on food composition tables and setting the limits of dietary intake of food, vitamins & minerals in World War 1.Biography Elsie was born in Surrey, United Kingdom. Her schooldays were spent in south east London where her favourite subject was Zoology. But she had a dedicated chemistry teacher how encouraged her to study chemistry at […]

April 18, 2015

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3:26 PM | e-Cig usage needs our attention
pharmtastic: An interesting study published earlier this month in PLOS ONE, whose major goal was to develop a murine [mouse] model to study the effects of e-cigarette smoke, found that repeated exposure to e-cig smoke resulted in inhibition of pro-inflammatory processes (leading to decreased concentration of pro-inflammatory cytokines) thereby making them more susceptible to bacterial and viral infections. The authors attribute these effects to the high levels of free radicals (although […]
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2:30 PM | Bioclipse 2.6.2 with recent hacks #1: Wikidata & Linked Data Fragments
Bioclipse dialog to upload chemicalstructures to an OpenTox repository.Us chem- and bioinformaticians have it easy when it comes to Open Science. Sure, writing documentation, doing unit testing, etc, takes a lot of time, but testing some new idea is done easily. Yes, people got used to that, so trying to explain that doing it properly actually takes long (documentation, unit testing) can be rather hard.Important for this is a platform that allows you to easy experiment. For many biologists […]
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2:01 PM | Do these dolls look familiar? In 1997 Intel released the...
Do these dolls look familiar? In 1997 Intel released the Pentium II processor and advertised it with commercials starring “BunnyPeople.” That name is not a reference to the animals with floppy ears; bunny suits are protective clothing worn by lab technicians who build microprocessors. The suits are designed to protect the processors from contamination, not the people wearing them.Intel stopped using this ad campaign around the same time overalls went out of style, but you can still […]
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11:35 AM | There’s a nice, but dense, paper out today (pdf here) from...
There’s a nice, but dense, paper out today (pdf here) from Singaporean biophysicists and chemical engineers at MIT demonstrating how existing theory fails to model the tying and untying of knots in polymers. Such knots are found in nature’s macromolecules: proteins and DNA. The most probable knot size (the ’metastable’ size) was found to vary non-monotonically (‘not strictly increasing’) with channel size, as per existing (Grosberg-Rabin) theory. In the […]
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10:57 AM | Chemistry Central and the ORCID identifier
If you are a scientist you have heard about the ORCID identifier by now. If not, you have been focusing on groundbreaking research and isolated yourself from the rest of the world, just to make it perfect and get that Nobel prize next year. If you have been working on impactful research, Nobel prize-worthy, and have been blogging and tweeting about your progress, as a good Open Scholar, you know ORCID is the DOI for "research contributors" and you already have one yourself, and probably also […]
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10:11 AM | CC-BY with the ACS Author Choice: CDK and Blue Obelisk papers liberated
Screenshot of an old CDK-basedJChemPaint, from the first CDK paper.CC-BY :)Already a while ago, the American Chemical Society (ACS) decided to allow the Creative Commons Attribution license (version 4.0) to be used on their papers, via their Author Choice program. ACS members pay $1500, which is low for a traditional publisher. While I even rather seem them move to a gold Open Access journal, it is a very welcome option! For the ACS business model it means a guaranteed sell of […]
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5:41 AM | 'A way of thinking' by Carl Sagan [Vídeo]
«Vivimos en una sociedad basada en la ciencia y la tecnología en la que nadie entiende nada sobre la ciencia y la tecnología» - Carl Sagan -

April 17, 2015

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9:37 PM | Science nightmares
It's been a long week of late nights and late consultations at work.Last night, I dreamed that I was up for my doctoral thesis defense and I couldn't find the presentation room, didn't have a presentation and I was pretty sure that I didn't have my Powerpoint slides. It has been quite a number of years (5+) since I somehow managed to squeak by successfully defended my thesis, so that was interesting. It has been the only time in my life where I have woken up from a dream and realized, "I […]
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9:36 PM | Job posting: experienced Ph.D. medicinal chemist, Seattle, WA
The Hutch is looking for an experienced medicinal chemist: The candidate is expected to utilize cutting-edge chemistry techniques to design and synthesize novel peptide conjugates, as well as the characterization of the physiochemical properties of both free and conjugated Optides. The position requires a strong background in protein chemistry, bioconjugation and analytical techniques. The chemistry will include highly potent/toxic chemotherapeutic agents and incorporation of radiolabeled […]
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6:21 PM | New paper opens the door to the study of a new class of materials
A new paper describes how an accurate statistical description of heterogeneous particulate materials, which is used within statistical micromechanics theories, governs the overall thermo-mechanical properties.
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6:05 PM | Feeding the pseudoscience rumor mill
Source.LA Times columnist Michael Hiltzik has a piece this week considering how (or whether) journalists should address pseudoscience and its purveyors.  He, along with others — Keith Kloor/Discover and Julia Belluz/Vox most recently —  have worried whether reporting on pseudoscience gives it more credibility and visibility than it deserves, particularly when the people involved are not otherwise newsworthy. And since most of the information about new science […]
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6:05 PM | Feeding the pseudoscience rumor mill
Source.LA Times columnist Michael Hiltzik has a piece this week considering how (or whether) journalists should address pseudoscience and its purveyors.  He, along with others — Keith Kloor/Discover and Julia Belluz/Vox most recently —  have worried whether reporting on pseudoscience gives it more credibility and visibility than it deserves, particularly when the people involved are not otherwise newsworthy. And since most of the information about new science […]
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4:20 PM | SAE 2014 Heavy-Duty Diesel Emissions Control Symposium
1. Introduction The Society of Automotive Engineers (SAE) 2014 Heavy-Duty Diesel Emission Control Symposium was, like its predecessors, hosted in Gothenburg, Sweden. This biennial two-day event attracted around 160 delegates. Most of the delegates (>95%) came from catalyst system and component suppliers as well as original equipment manufacturers (OEMs). A few delegates came from academia,... The post SAE 2014 Heavy-Duty Diesel Emissions Control Symposium appeared first on Johnson Matthey […]
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2:37 PM | Beyond the lithium ion - a significant step toward a better performing battery
Researchers have shown they can replace the lithium ions, each of which carries a single positive charge, with magnesium ions, which have a plus-two charge, in battery-like chemical reactions, using an electrode with a structure like those in many of today's devices.
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2:01 PM | Check out our trailer of CHF’s new video about Gordon Moore and...
Check out our trailer of CHF’s new video about Gordon Moore and his influence on the world. Go to Chemheritage.org/Moore after 4:30 p.m. EDT to watch the full film.Tomorrow we revisit an Intel advertising gem from the 1990s.
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1:44 PM | Don't be a Rheology Fool
'Nuff said.Previous YearsApril 17, 2013 - Polymers from Elemental SulfurApril 17, 2012 - Some Novel Polymer Chemistry ReactionsApril 17, 2007 - Rapid announcements across a campus - the Tragedy at VTU
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9:36 AM | Optical resonance-based biosensors designed for medical applications
Besides achieving greater resolution and sensitivity, the materials used in these new devices are much cheaper and more versatile than the ones used in current technologies (mainly gold and noble metals) so they could offer a potential alternative in the design of biomedical sensors.
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9:00 AM | Framework compounds: metal-organic transformations
The mechanosynthesis of cage compounds suitable for storing gases can be monitored in real-time with the help of X-ray powder diffraction.
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8:27 AM | Types of Antifreeze
The antifreeze most commonly used in engines includes ethylene glycol (or propylene glycol) and a mixture of anti-corrosion additives and dyes. For many years, only one type of antifreeze was commercially available, but recently new products have been developed. These new products also rely on ethylene or propylene glycol to lower the freezing point, but [...]
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7:35 AM | Engineer improves rechargeable batteries with MoS2 nano 'sandwich'
Molybdenum disulfide sheets - which are 'sandwiches' of one molybdenum atom between two sulfur atoms - may improve rechargeable lithium-ion batteries, according to the latest research.
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2:55 AM | Publication of the week, number 73, 17th April 2015
This week several publications could have aspired to be my ASAP of the week. I chose the one by Fürstner in Angewandte describing the total synthesis of 5,6-dihydrocineromycin B. A paper which is full of interesting titbits of useful information. This compound is one of a family of antibiotics whose activity may need to be … Continue reading Publication of the week, number 73, 17th April 2015 →

April 16, 2015

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11:53 PM | “What is true for E. coli is true for the...
“What is true for E. coli is true for the elephant” Jacques Monod’s famous pronouncement on the unity in biochemistry stated that what was true for E. coli held for the elephant (reformulating an earlier proposition by Kluyver). Kluyver’s vision was of functional, not compositional, unity, that a variety in biochemical composition both hid and manifested unity of function. It can be readily expanded beyond this original remit to discuss universality in for example, […]
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10:24 PM | Thanks to All My Readers and Tweeps!
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