October 22, 2014

7:06 PM | Clot dissolver tPA’s tardy twin could aid in stroke recovery
Tissue-type plasminogen activator, meet urokinase-type plasminogen activator. You guys probably know each other. The post Clot dissolver tPA’s tardy twin could aid in stroke recovery appeared first on Lab Land.
4:22 PM | Why is Ebola so scary?
Unless you've been living under a reasonably sizable rock for the last few months, it can't have escaped your attention that the world has yet another terror to throw on the mountain of things we should be scared of: Ebola. The ongoing situation in Africa is the largest Ebola outbreak in history and has seen the disease spread beyond Africa for the first time. At the time of writing this, nearly 10,000 people have become infected, almost half of whom have died. This number is […]
1:22 PM | From Campus DJ to Kaluza Prize Winner, Josie Clowney Connects to Science
To be clear, E. Josephine Clowney, the 2014 winner of the $5,000 ASCB Kaluza Prize supported by Beckman Coulter, says she met her husband and learned to be a good scientist as a disc jockey for her college radio station. Leaving the husband part aside, Clowney explains the scientist part this way—playing all kinds of music on the highly eclectic WCBN-FM at the University of Michigan (UMich) in Ann Arbor, including music she didn't think at first was music, such as a Thai elephant […]

October 20, 2014

3:41 PM | What not to miss at #TMM2014
> Next week, close to 500 researchers, clinicians, trainees, industry and government representatives will gather in Ottawa for some of the best the stem cell and regenerative medicine research community has to offer. The third Till & McCulloch Meetings is taking place over three days, October 27-29 and we’re going with the theme of three...Read more
2:20 PM | Moral Time: Does Our Internal Clock Influence Moral Judgments?
Does morality depend on the time of the day? The study "The Morning Morality Effect: The Influence of Time of Day on Unethical Behavior" published in October of 2013 by Maryam Kouchaki and Isaac Smith suggested that people are more honest in the mornings, and that their ability to resist the temptation of lying and cheating wears off as the day progresses. In a series of experiments, Kouchaki and Smith found that moral awareness and self-control in their study subjects decreased... Read […]

October 19, 2014

12:09 PM | Ebola- Face The Fear
Ebola, the emerging threat from Africa, is without doubt a lethal killer. This serious threat has a grossly high mortality rate; the fatality rate for Ebola’s haemorrhagic fever (now known […]

October 17, 2014

12:35 PM | Right Turn: “Of all the senses, sight must be the most delightful”
. I don’t disagree with that quote by educator and humanitarian Helen Keller, a woman who overcame her inability to see, hear and speak, and graduated from college in 1904. However, I’m extremely squeamish when it comes to eyes. Perhaps it started in grade 8 science class when we had to dissect a cow’s eye…?...Read more

October 15, 2014

8:06 AM | Evolutionary Theories of Obesity
Obesity, evolution, medicine, theories, population, genetics, genome
4:00 AM | Laugh in the Face of Deadlines! Write That Research Paper with a Smile on Your Face!
Your latest western blot may be worth a thousand words but you will need to write1,000 words to go along with it. So how to choose which 1,000? To help with the essential task of writing up your latest research, we found some free advice (which will offset the cost of “free” open access publishing). ASCB photoYour latest western blot may be worth a thousand words but you will need to write1,000 words to go along with it. So how to choose which 1,000? To help with the essential […]

October 14, 2014

6:08 PM | Revisiting landmark folate-autism study
Geneticist Joe Cubells is re-examining a Chinese study of folic acid supplementation and its impact on autism risk The post Revisiting landmark folate-autism study appeared first on Lab Land.
1:09 PM | Update from the Clinic: September
. Welcome to your Update from the Clinic for the month of September. There’s a mixture of news from the cancer stem cell companies and immunotherapy companies this past month. Amongst other things, the FDA removed the previously imposed partial hold on one of OncoMed’s therapeutics; Opexa Therapeutics announced its next therapeutic program; and, Harvard...Read more
1:00 PM | New iBiology Videos Explore the Link Between Discovery and Medicine
"Interest in biology has never been higher,” says Louis Reichardt, emeritus professor of physiology at University of California, San Francisco (UCSF). And yet, as federal research funding declines, Reichardt worries that many graduate students are despairing of their prospects for productive research careers. “It takes some ingenuity now to find future opportunities in science,” he says. In recent years, Reichardt has devoted his own ingenuity to helping students find these […]

October 12, 2014

10:22 PM | The Psychology of Procrastination: How We Create Categories of the Future
"Do not put your work off till tomorrow and the day after; for a sluggish worker does not fill his barn, nor one who puts off his work: industry makes work go well, but a man who puts off work is always at hand-grips with ruin."        Hesiod in "The Works and Days" Paying bills, filling out forms, completing class assignments or submitting grant proposals – we all have the tendency to procrastinate. We may engage in trivial activities... Read more
2:02 AM | The most promising treatments for ebola are based on basic immunology-part 2
One of the more peculiar, historic and almost cinematic treatments being discussed in the midst of the ebola crises is the use of blood transfusions. In movies, the blood of a survivor or someone special is often supposed to have some sort of mystical effect on the (usually villainous) recipient. It turns out, blood transfusions […]

October 10, 2014

2:05 PM | Need a really small number?
Then you can use DNA origami. Ask Yonggang Ke in biomedical engineering for advice. The post Need a really small number? appeared first on Lab Land.
1:30 PM | Right Turn: Why you should vote for Stem Cell Person of the Year
> We assume there is no real argument to be made here. It’s more than just popularity or who has been in the news most often over the past year. The annual call for nominations and the selection of Stem Cell Person of the Year by readers of Paul Knoepfler’s blog – a.k.a. the stem cell...Read more

October 09, 2014

1:00 PM | Regenerative Medicine Deal Review: September
Welcome to your deal review for the month of September. There was some healthy news flow around cell-based immunotherapy companies this past month, heating up a space that is already ablaze with activity. Undoubtedly the company that took the spotlight was Adaptimmune, which completed a venture capital (VC) round of over $100 million! The money...Read more
4:00 AM | Show Congress the Face of Biomedical Research—Your Face
ASCB’s third annual We Are Research campaign needs you and your labmates to put a face on biomedical research. At your next lab meeting, lab happy hour, or lab karaoke party, round up the gang, snap a photo of your team, and submit it ASCB’s third annual We Are Research campaign needs you and your labmates to put a face on biomedical research. At your next lab meeting, lab happy hour, or lab karaoke party, round up the gang, snap a photo of your team, and submit it here by […]

October 08, 2014

7:30 PM | Many colors in the epigenetic palette
Methylation, an epigenetic modification of DNA, comes in several colors. The post Many colors in the epigenetic palette appeared first on Lab Land.
6:13 PM | X Inactivation: Equality Between the Sexes
Since women have two X chromosomes (XX) and men have only one (XY), the body needs a way of ensuring women don’t get a double helping of X chromosome genes. […]
12:02 PM | ASCB Member William Moerner Wins Nobel Along with Eric Betzig and Stefan Hell
The resolution of traditional light microscopy was long thought to be limited due to the maximum diffraction of light. But today's Nobel Prize winners in Chemistry changed that. William Moerner, Eric Betzig, and Stefan Hell won for cleverly circumventing this limit and imaging at a whole new scale known as nanomicroscopy or superresolution imaging.  William Moener, Eric Betzig, and Stefan Hell (left to right)won the 2014 Nobel Prize in Chemistry for pioneering nanomicroscopy.The […]

October 07, 2014

8:00 PM | Pathomx v3.0.0 Release Candidate 2
The final release candidate for Pathomx v3.0.0 is available for both Mac and Windows. This latest version features the new IPython backend providing parallel processing (via IPython ipcluster support), numerous bugfixes and improvements to the UI and figure outputs. While a development version it is considered stable enough for regular use. If you’re a current user of Pathomx, please download and test with your own hardware and data, see how it holds up and then report any […]

October 06, 2014

6:45 PM | Bits from HIV + Aging conference
Missed diagnoses and medical journeys The post Bits from HIV + Aging conference appeared first on Lab Land.
3:34 PM | Nobel Prize for place cells + grid cells
Connection to neuroscience research performed at Yerkes The post Nobel Prize for place cells + grid cells appeared first on Lab Land.
2:20 PM | Sugar rush: The development of glucose-sensitive beta cells from embryonic precursors
> “Wow, my mouth just got diabetes.” Such are my immediate thoughts after taking a bite out of a red velvet cupcake.  Though I must qualify: by cupcake, I mean a skyscraper of frosting carefully balanced on a minimal crumbly foundation. Making such a hyperbolic statement heightens our awareness that diabetes involves intolerably high blood...Read more

October 04, 2014

12:25 PM | Former ASCB President Bruce Alberts Receives the National Medal of Science
Bruce Alberts, professor at the University of California, San Francisco (UCSF), who served as ASCB president in 2007, was just named one of the nation's top scientists by President Obama. Alberts and nine others are recipients of the National Medal of Science, the Nation's highest honor for individuals who have made outstanding contributions to science and engineering. Alberts will be presented the medal in a ceremony at the White House later this year. Bruce Alberts is a renowned […]

October 03, 2014

2:43 PM | The most promising ebola treatments are based on basic immunology
Though for many of us, the ebola crises is oceans away, the epidemic lies heavily on the hearts and minds of people all over the world. For some researchers, public health officials and drug developers, it is the driving force of all daily activity. Right now, there are two vaccines and eight treatments being developed […]
2:11 PM | Refining tools for Big Data
Developing software to analyze the truckloads of data The post Refining tools for Big Data appeared first on Lab Land.
1:00 PM | Right Turn: There’s beauty in science
. The colourful, beautiful, whimsical, original, intriguing (I could go on) images that were submitted to CCRM for its Cells I See contest are live on Facebook for your viewing pleasure and votes. Until October 18, 2014 people are encouraged to “like” their favourite image. The one with the most likes will be this year’s...Read more

October 01, 2014

9:38 PM | The Winners of the $5K, $3K, $1K Kaluza Prizes Are…
Eleanor (Josie) Clowney , a postdoc at Rockefeller University who did her graduate work at the University of California, San Francisco, has been named the winner of the 2014 $5,000 ASCB Kaluza Prize for outstanding research by a graduate student. The Kaluza Prizes are supported by Beckman Coulter. Clowney won for her breakthrough work on olfactory neurons performed in Stavros Lomvardas’ lab. Her work provides a new perspective on how acute transcriptional specificity can be achieved […]
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