Posts

March 27, 2015

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7:16 PM | Recording seizures from within the brain
Get out your tin foil hat: newer deep brain stimulation devices allow doctors to record seizures over many months The post Recording seizures from within the brain appeared first on Lab Land.
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1:36 PM | Right Turn: End of an era, almost
> This is my final post as co-editor of Signals, and in sitting down to draft it, I found myself struggling to find words. How do you sum up six years of blogging? Quite simply, you don’t. However, as this also marks the end of the Stem Cell Network’s involvement with Signals, it was suggested...Read more

March 25, 2015

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3:14 PM | The science of three-parent children
2015 has already been a significant year in the field of human medicine as February saw the UK become the first country in the world to legalise the generation of so-called 'three-parent' children. This marks a milestone for preventative genetics and embryology and offers hope to many people around the UK and beyond who would be unable to have healthy children otherwise. The votes to bring this into law were fairly comfortably won by those in favour - 382 vs 128 in the House of Commons (the […]
Editor's Pick
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12:00 PM | Update from the Clinic: February
. Welcome to your Update from the Clinic for the month of February. Northwest Biotherapeutics received approval from Health Canada to proceed with its ongoing Phase 3 clinical study in Glioblastoma multiforme at clinical sites in Quebec. Sangamo and bluebird bio both had news on the regulatory progress of their respective beta-thalassemia programs. Kite Pharma...Read more

March 24, 2015

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1:29 PM | Such a long journey – Europe approves retinal cell therapy based on decades of good science
> At one of my very first Canadian Stem Cell Network Annual General Meetings, when I was just a couple of years into my stem cell biology training, I remember sitting down just after lunch when a jovial Italian man sauntered up to the stage and apologized to the audience for the timing of his...Read more

March 23, 2015

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6:38 PM | Regrouping on fragile X drug strategies
Several clinical trials for people with fragile X syndrome didn't meet organizers' goals. The field is regrouping. The post Regrouping on fragile X drug strategies appeared first on Lab Land.
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2:09 PM | What’s in a name? A cancer stem cell by any other name is still a stem cell – or is it?
> I have previously written about the phrase “cancer stem cell,” and how it can be misleading for researchers and the public alike. As scientists, we go through great pains to be specific in our use of ‘cancer stem cell’ (CSC), referring to a cell that possesses the stem cell abilities of self-renewal and multi-lineage...Read more

March 20, 2015

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10:56 PM | Life or Death?
Streptococcus pneumonia has been recognised as the major cause of pneumonia since the late 19th century. This bacterium also leads to the development of other infections such as, meningitis, bronchitis, septic arthritis and brain abscess. Sounds awful, doesn’t it? Well, don’t worry; this bacterium is easily overcome by a good strong dose of antibiotics. Or, […]
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12:00 PM | Right Turn: No horsing around with this grand gesture
. American media and telecom billionaire John Malone, along with his horse-breeding wife Leslie, have generously donated U.S. $42.5 million to Colorado State University to launch the CSU Institute for Biologic Translational Therapies to develop regenerative medicine treatments to benefit animals and people. The university says the new institute “will be unique in its focus...Read more

March 19, 2015

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4:29 PM | Potential HIV drugs hit three targets at once
News from the American Chemical Society meeting in Denver The post Potential HIV drugs hit three targets at once appeared first on Lab Land.

March 18, 2015

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3:25 PM | No more monkeying around – promising results using stem cells to treat Parkinson’s disease
Earlier this month, Harvard Medical School researchers published a brief report in Cell Stem Cell, which showed in non-human primates – in this case monkeys – that Parkinson’s disease symptoms could be alleviated using stem cell therapy. Using induced pluripotent stem (iPS) cells made from monkeys, they were able to make neurons outside the body...Read more

March 17, 2015

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1:30 PM | Grow your brains: Neural stem cells in 1 minute.
> Many of us only become acutely aware of our brain when it’s not working quite right. Like, say, if we have a migraine, or are diagnosed with a mental illness. Or we fall on the ice and give ourself a concussion that affects our vision, motor skills and other cognitive functions (as was my experience...Read more

March 16, 2015

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7:28 PM | ACC 2015: Newer heart risk calculator may better accounts for racial differences
ACC/AHA risk calculator includes effects from arterial stiffness, which affects African Americans more than Caucasians The post ACC 2015: Newer heart risk calculator may better accounts for racial differences appeared first on Lab Land.
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3:01 PM | Cell Therapy 2.0 – warts and all
> The last 15 years of stem cell research have been full of hope and promises – some of it delivered upon, most of it not quite there yet, and some of it miserably failed. I guess that is to be expected in a highly experimental area of medicine, but one of the most striking...Read more

March 15, 2015

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10:41 PM | Mothers
Happy Mothers’ Day, all. On this Sunday, you may be reminded of famous mothers throughout history: Olympias (mother of Alexander the Great), Mother Theresa, Jackie Kennedy, Angelina Jolie. You may even be tearfully reminded of characters in movies that have had unfortunate experiences involving their mothers, such as poor Nemo, in Finding Nemo, who loses his […]

March 13, 2015

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6:39 PM | Who regulates the regulators? Drosha
February 2015 paper in Molecular Cell on regulation of Drosha from Zixu Mao and colleagues The post Who regulates the regulators? Drosha appeared first on Lab Land.
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1:15 PM | Right Turn: Super Cells in Newcastle
> Super Cells has grown wings and flown over to Newcastle. Yes, I know, you’re struck dumb at the improbability of this terrible metaphor, but far less than I am: having reviewed every word, every animation, every image, every concept of this exhibit, I’m completely baffled at how the feather follicle stem cells snuck in there...Read more

March 12, 2015

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7:50 PM | Are TrkB agonists ready for translation into the clinic?
7,8-dihydroxyflavone can be found in plants such as Godmania aescufolia, and has positive effects in animal models of several neurological diseases. The post Are TrkB agonists ready for translation into the clinic? appeared first on Lab Land.

March 11, 2015

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5:49 PM | Next generation sequencing roundup
Incidental findings, insurance coverage, FDA regulation... The post Next generation sequencing roundup appeared first on Lab Land.
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12:00 PM | Hot off the press: DNA-based bioprinting of tissues
. By S. Amanda Ali, PhD What do biomaterials mean to you? For this orthopaedic scientist, the first thing that comes to mind is the total joint replacement: artificial knees, hips and shoulders made from a variety of materials to reproduce joint function and suit each patient. Introduced in the 1960s to the field of...Read more

March 10, 2015

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10:32 PM | Sniffing isn’t just for dogs
Dogs sniff each other to receive information on each others’ gender, diets and emotional states. Male elephants and giraffes sniff females to discover when they will be in oestrus, i.e. the reproductively active state. Mice sniff each other in order to determine a social hierarchy. In fact, the olfactory sense is used throughout the animal kingdom […]
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3:28 PM | BAI1: a very multifunctional protein
Research on brain cancer leads to a discovery in the area of learning and memory The post BAI1: a very multifunctional protein appeared first on Lab Land.
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12:00 PM | Biomaterials 101– A fate-twister
  By guest blogger Jane Cheung With contributions from Casandra Gardner, PhD and Joanna Fromstein P.Eng (Centre for Commercialization of Regenerative Medicine) “Fate has brought us here.” “This is my destiny.” We often read or hear these phrases in books or movies. Often times, as the plot goes on, the main characters will utter, “We...Read more

March 09, 2015

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8:37 AM | Wooey: Simple, automated web UIs for Python scripts
Wooey is a simple web interface (built on Flask) to run command line Python scripts. Think of it as an easy way to get your scripts up on the web for routine data analysis, file processing, or anything else. Inspired by what Gooey can do, turning ArgumentParser-based command-line scripts into WxWidgets-based GUIs, I thought I’d see if I could do the same for the web. I’m still not sure if the result is beautiful or horrific. Wooey (see what I did there?) uses the same, […]

March 08, 2015

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6:17 PM | “She’s strong for a girl”: The Negative Impact of Stereotypes About Women
This is a guest blog post by Ulli Hain (Twitter: @ulli_hain, Email: hain.ulli[at]gmail.com). Ulli is a postdoctoral researcher in the field of autophagy and also a science writer/blogger. Her blog Bench and Beyond reports on interesting scientific studies and explores life as a scientist including issues of gender and science. We have all heard the stereotypes: women can’t drive, they don’t understand computers, and how many blondes does it take to screw in a light bulb? […]

March 06, 2015

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1:00 PM | Right Turn: Commercializing iPSCs – Infographics
. The beauty of an infographic (or two) is it speaks for itself.   Shared with permission of BioInformant: http://www.bioinformant.com/   Our regular feature, Right Turn, appears every Friday and we invite you to submit your own blog to info(at)ccrm.ca. We encourage you to be creative and use the right (!) side of your brain....Read more

March 04, 2015

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2:34 PM | How online outreach adds value to scientific research
> Scientists: I have some questions. Have you ever written a blog post about your field? Tweeted a link to a new scientific publication? Joined a forum discussion about the latest research? As it turns out, your likelihood of answering “yes” to one or more of these questions is no better than a coin flip....Read more

March 03, 2015

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2:49 PM | OMICS Workshop: An introduction into systemic tools for diverse cell populations
Guest post by Anastassia Voronova Sequencing platforms and techniques are undergoing a revolutionary and transformational progress. As a stem cell researcher, I value the opportunity for continued professional education to maintain a grip on the latest technologies. In late February, I had such an opportunity, and participated in the Stem Cell Network’s first -OMICS Workshop focused on...Read more

March 02, 2015

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4:03 PM | Does Thinking About God Increase Our Willingness to Make Risky Decisions?
There are at least two ways of how the topic of trust in God is broached in Friday sermons that I have attended in the United States. Some imams lament the decrease of trust in God in the age of modernity. Instead of trusting God that He is looking out for the believers, modern day Muslims believe that they can control their destiny on their own without any Divine assistance. These imams see this lack of trust in God as... Read more

February 28, 2015

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11:08 PM | Heady suggestions
Assertions by the Italian neuroscientist, Sergio Canavero of the Turin Advanced Neuromodulation Group, have caught the media’s attention this past week. In fact, head transplants were first proposed by him in 2013, as a means to “extend the lives of people whose muscles and nerves have degenerated or whose organs are riddled with cancer”. Canavero […]
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