August 21, 2014

12:35 PM | The CellSlam that Would Not Die Steps out Again at Philly 2014
Back from the undead, the 2014 "Zombie Cellslam," the Public Information Committee's stand-up science slam, is slouching toward Philadelphia where it will take the stage again at an Annual Meeting of the ASCB for the first time in five remarkably peaceful years. No more. The 2014 Zombie Cellslam, so named because it will not die, is set for Monday evening, December 10, at the joint ASCB/IFCB meeting in the Pennsylvania Convention Center. It will offer a variety of wit, music, and outrageously […]
10:07 AM | Artificial Super-intelligence Poses an Existential Threat to Mankind
Artificial super-intelligence. Billed to be one of the largest advancements in our technological capabilities as yet to be achieved within the current century. Over 80% of experts in the field […]

August 20, 2014

5:42 PM | Maturing brain flips function of amygdala in regulating stress hormones
Scientists are still discovering new information about the function of the amygdala, a region of the brain important for learning about threats The post Maturing brain flips function of amygdala in regulating stress hormones appeared first on Lab Land.

August 19, 2014

2:13 PM | Inside a cancer stem cell researcher’s toolbox: Xenotransplantation
> In previous posts, I have alluded to the fact that studying cancer in a dish (in vitro) is not optimal (here and here). Today, I give you the next essential tool in a cancer stem cell (CSC) researcher’s toolbox: xenotransplantation. Xenotransplantation is an impressive mouthful that simply means the transplantation of living cells, tissues,...Read more

August 18, 2014

1:15 PM | Update from the Clinic: July
. Welcome to your Update from the Clinic for the month of July. The cancer stem cell companies were back in the news last month. OncoMed initiated its ALPINE clinical trial of Tarextumab for pancreatic cancer, while Stemline Therapeutics announced an investigational new drug (IND) for SL-401 and initiation of clinical trials in two blood...Read more
12:00 PM | Women in Science- Do We Need to Worry About Gender Bias?
Women have long been battling for their rights – the right to work, the right the vote, the right to equal pay.  But is there still a gender bias in […]
4:00 AM | Proteins and Prejudice—The Mr. Darcy of Protists, Giardia, Defies the Canonical Mitotic Checkpoint Proteins
It is a truth all but universally acknowledged that a eukaryotic cell entering mitosis must be in want of the canonical proteins for mitotic checkpoints. And then there is Giardia intestinalis. A notorious flagellate pathogen, this binucleate protist belongs to one of the major eukaryotic lineages now called the "Excavates." Like all other Excavates, Giardia is weird, says Zacheus Cande of the University of California, Berkeley, but weird in a good way because of its ancient evolutionary […]

August 15, 2014

7:27 PM | A new frame of reference — on ribosome frameshifting
Viral genes do frameshifting. Human genes do it too. Scientists want to use it to expand the genetic code. Emory scientists are figuring out the mechanism. The post A new frame of reference — on ribosome frameshifting appeared first on Lab Land.
3:24 PM | Right Turn: The creative process
I’m starting this post with an image that more or less sums up my life over the past two weeks, which has been rather intensely focused on creativity. This was the second time I traveled to Banff to be part of the Science Communications program at the Banff Centre, a very worthwhile sojourn for scientists...Read more
1:18 PM | Gene Therapy- The Future of Schizophrenia Treatment?
A study was recently released in Nature looking at genes linked to schizophrenia with the hope of helping researchers to find a whole host of brand new treatments for patients […]

Schizophrenia Working Group of the Psychiatric Genomics Consortium (2014). Biological insights from 108 schizophrenia-associated genetic loci., Nature, 511 (7510) 421-7. PMID:


August 14, 2014

2:02 PM | Nontraditional Science Careers: Consultant
The secret is out. There is life beyond the lab or the classroom for someone with a PhD in molecular biology, especially in the biotech and pharmaceutical industry. And yet many of these business careers have little to do directly with bench expertise but instead call on doctoral level training in analysis, planning, and communication. Those are the key skills that serve Jason Huhn and Danielle Haney, recent PhD graduates who are happily pursuing fast-paced, well-paid office-based careers […]

August 13, 2014

4:40 PM | Stroke Services in London and Manchester – A successful example of centralisation?
150,000 people suffer a stroke each year in England, of which 40,000 die. Although it is the 3rd largest cause of death, it is also the largest cause of disability […]
9:47 AM | Stromal Vascular Fraction SVF Cells
Stromal vascular fraction or SVF cells is a medical term that describes a heterogeneous kind of cell that are typically found in adipose “fat” tissue. SVF cells are not the same as “stem cells” but constitute about 2/3rd of all cells in the human body. SVF Cell Manipulation – VIDEO The remaining cells are called adipocytes. […] The post Stromal Vascular Fraction SVF Cells appeared first on Regeneration Center of Thailand.

August 11, 2014

2:32 PM | It’s Never Lupus? Think again…
Those of you familiar with a certain misanthropic maverick MD will no doubt be familiar with the phrase “it’s never lupus”. Unfortunately, in the real world, it IS sometimes lupus […]
1:30 PM | Regenerative Medicine Deal Review: July
. Welcome to your deal review for the month of July. There was financing activity this past month as StemCells and Fate Therapeutics each secured $20 million in funding. Bluebird bio was busy with the acquisition of a privately-held genome editing company; clearly a strategic move to strengthen its gene therapy pipeline. Sernova was in...Read more

August 08, 2014

1:30 PM | Right Turn: All about regeneration – navigating fact and fiction
. The following scene from Family Guy offers a glimpse into both the tone and subject matter of this week’s Right Turn. Being an avid lover of superheroes, monsters and all things supernatural, the topic of healing and limb regeneration has always been a subject I find vastly exciting. If you’re having trouble understanding what...Read more
1:15 PM | Pilot human trial for image-guided cancer surgery tool
Fluorescent dye helps surgeons see tumor margins. Results of pilot trial at Penn published, trial ongoing at Emory. The post Pilot human trial for image-guided cancer surgery tool appeared first on Lab Land.
10:30 AM | Memoirs Of A Microbiologist; 11 Things I Wish They’d Told Me Before Working In The Lab
After recently graduating from Newcastle University with a 1st Class BSc with honours in Medical Microbiology (no bragging here, honest) I have been lucky enough to start employment in a […]

August 07, 2014

1:53 PM | New NIH 3D Print Exchange Offers Open Access To Three-Dimensional Printing Tools
In Hollywood and in 3D molecular printing, you start with a script. But the scripts that Darrell Hurt offers bioscience researchers help them to make molecular discoveries more easily. Hurt is the section head at the Computational Biology Bioinformatics and Computational Biosciences Branch at the NIH, where he recently launched the NIH 3D Print Exchange. The Exchange offers open-access to ready-to-use scripts, the instructions that drive 3D printers, so scientists can […]

August 06, 2014

8:40 PM | Contraception and HIV risk
High quality information on a contentious public health issue The post Contraception and HIV risk appeared first on Lab Land.

August 05, 2014

1:34 PM | Gene editing technique makes disease study almost as easy as flipping a switch
> Imagine you are about to interview someone, and rather than receiving a full reference letter, your candidate is described with but a single word. Do you think you’d get the whole picture? Of course you wouldn’t, but depending on the word chosen, you could make a decision. For example, “disorganized” or “unreliable” seem like...Read more

August 04, 2014

4:00 AM | Room with a View—Forbes Names NHLBI’s Greg Alushin to Its “30 under 30 in Science” List
It's rare to find a young scientist in a big office, yet Gregory Alushin, age 29, has generous space, a U-shaped desk, and a floor-to-ceiling window with a view of the NIH campus. He is semi-apologetic about the arrangement, insisting that it's only temporary. "We're going to have to leave this place in a few months," Alushin hastily explains. "Another institute had just moved out of this space so we got to be the temporary sole occupants." His lab was founded only seven months ago, says […]

August 01, 2014

11:00 AM | The Heterogeneity of Cancer and DNA as a Prognostic Marker: The Truth is in our Blood
Tumours are incredibly heterogeneic- that is that they have different properties including morphology (how they look), metabolism (the processes they use to generate energy), proliferation (how fast they grow, divide […]

July 31, 2014

4:00 AM | ASCB Rescues Federal Scientists from Capitol Hill Sausage Grinder
Making sausage and making legislation are not spectator sports but someone has to keep an eye on what's going into the mix. A case in point is the release by the Senate Appropriations Committee last Friday of its version of the bill that will fund the departments of Labor, Health and Human Services, and Education for FY15. At first glance, the bill looks like typical Capitol Hill sausage. But look closer. Tucked deep inside the bill are changes that, if they become law, will help NIH scientists […]

July 30, 2014

5:26 PM | Antibiotic resistance enzyme caught in the act
ICYMI, part of an increasing interest in antibiotic resistance at Emory, coming from many angles: biochemistry/microbiology/infectious diseases. The post Antibiotic resistance enzyme caught in the act appeared first on Lab Land.
2:58 PM | Fighting HIV, biomedical and behavioral hand in hand
Emory epidemiologist Kristin Wall gets attention at AIDS 2014 with a presentation on the importance of couples counseling The post Fighting HIV, biomedical and behavioral hand in hand appeared first on Lab Land.
1:42 PM | Science in the News: The 2014 Ebola Outbreak
If you’ve been watching the news recently, you’ll probably have seen reports on the Ebola outbreak in West Africa. Around 673 people in Guinea and Liberia have died so far […]

Dixon MG, Schafer IJ & EIS officer, CDC (2014). Ebola viral disease outbreak - west Africa, 2014., MMWR. Morbidity and mortality weekly report, 63 (25) 548-51. PMID:

Gatherer, D. (2014). The 2014 Ebola virus disease outbreak in West Africa, Journal of General Virology, 95 (Pt_8) 1619-1624. DOI: 10.1099/vir.0.067199-0

4:00 AM | Lydia Villa-Komaroff Learned in the Lab “What It Might Be Like to Fly”
"I grew up in a very big family in a very small house," says Lydia Villa-Komaroff. That house was in Santa Fe, New Mexico, where few Mexican-American kids like herself were lucky to even finish high school. But Villa-Komaroff knew from a young age that she wanted to become a scientist. She remembers when she was nine, hearing her uncle talking about his work as a chemist and deciding that this sounded like the career for her. "All children are scientists, but... I think it gets lost because […]

July 29, 2014

7:59 PM | Socialization relative strength in fragile X longitudinal study
Adaptive behavior covers a range of everyday social and practical skills, including communication, socialization, and completing tasks of daily living such as getting dressed. In a recent study, socialization emerged as a relative strength in boys with fragile X, in that it did not decline as much as the other two domains of adaptive behavior measured: communication and daily living skills. The post Socialization relative strength in fragile X longitudinal study appeared first on Lab Land.
5:55 PM | Debunking detour to DNA
We use most of our brains. So there, ScarJo. But do we use most of our DNA? The post Debunking detour to DNA appeared first on Lab Land.
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