October 31, 2014

6:00 PM | How Do You Like Your Eggs in the Morning? Frozen and Dipped in Liquid Nitrogen
If you’ve been watching the news or reading the paper recently, you’ll probably have heard about Apple and Facebook’s announcement that they will fund egg freezing procedures for their female […]
3:19 PM | Rules of thumb for drug discovery
*The* Chris Lipinski is talking at Winship Nov 5 The post Rules of thumb for drug discovery appeared first on Lab Land.
12:03 PM | Right Turn: A Halloween gift that keeps on giving (and we’re not talking about cloning)
. Hobgoblins, hocus pocus, hayrides and haunted houses…Happy Halloween! Do those words conjure up a feeling of dread or does a wave of happiness wash over you when you hear Happy Halloween? Perhaps more relevant here, does the word Halloween ever make you think of stem cells? Stem cells and Halloween don’t typically go together...Read more

October 30, 2014

12:37 PM | Trainee talks – where you hear about the really cool stuff
> One of the consistent themes of the Till and McCulloch Meetings (#TMM2014) is its commitment to having students and postdocs on stage presenting their work. These sessions have been regularly cited by my colleagues as the most interesting and engaging sessions with the most new data. The last few meetings they have called these...Read more
4:00 AM | Serving in the Korean Military, Kaluza Winner Eunyong Park Had Time to Change His Mind
Two long years in the South Korean military gave Eunyong Park time to change his mind and his career direction toward biology, a change that led to his winning this year’s $3,000 Kaluza prize for excellence in graduate research. Park won the ASCB Kaluza Prize, which is supported by Beckman Coulter, for his remarkable work at Harvard University deciphering the mechanisms of protein translocation in living cells. When cells make new proteins that are destined to reside in the membrane or […]

October 29, 2014

7:35 PM | Explainer: the locus coeruleus
Critical early site of neurodegeneration The post Explainer: the locus coeruleus appeared first on Lab Land.
1:38 PM | Scaling up to a speck of dust
DNA bricks almost large enough to see with the naked eye The post Scaling up to a speck of dust appeared first on Lab Land.
12:55 PM | Using cell circuits to program cellular outcomes
> One of my favourite things about the Till and McCulloch Meetings (#TMM2014) is the careful thought that goes into session organization. The balance of basic science, ethics, engineering, and industrial and clinical applications has always been a nice feature of the meeting. Having just listened to the speakers in the Systems, Synthetic & Applied Stem...Read more

October 28, 2014

12:52 PM | Our People: David Burgess and Renato Aguilera Named as PIs in Sweeping NIH Workforce Diversity Initiative
Two longtime ASCB members and longtime advocates for bringing underrepresented minorities into bioscience have been named as PIs in grants from the National Institutes of Health (NIH) under its wide-ranging "Enhancing the Diversity of the NIH-Funded Workforce" program. Renato Aguilera (third from left) shown with his fellow BUILD program PIs at the University of Texas El Paso. Photo credit: J.R. Hernandez, UTEP News ServiceTwo longtime ASCB members and longtime advocates for bringing […]
12:04 PM | How relationships and collaboration breed scientific breakthroughs
> Last month, Signals re-posted a blog entry of mine from The Black Hole where I lamented the lack of teamwork in the life sciences. There are, however, always exceptions and I want to highlight one such exception that took the field of blood stem cell expansion by storm last month. It was also presented...Read more

October 27, 2014

6:48 PM | Two Stem Cell Beliefs Debunked
Two recent papers may have upturned two common beliefs about adult stem cells. The esophagusRead more about Two Stem Cell Beliefs DebunkedComments
9:07 AM | The Controversy of the Birth of the Modern Cell
In secondary school I remember being told wen being taught about the cell that the mitochondria, which has its own DNA and produces the energy that is required in the […]

October 26, 2014

6:03 PM | Pathomx v3.0.2 released
Pathomx v3.0.2 has been released for both Windows and MacOS X. This marks the first stable, bug-fixed release for the v3.0 line featuring the new IPython-kernel with cluster support for parallel processing of tools. This latest version adds a number of important features over the previous v2.0 series: IPython backend including a live in-process kernel for debugging and data exploration Pandas dataframe-based data handling Inline code editor: edit the Python code for […]

October 24, 2014

1:24 PM | Right Turn: New StemCellShorts illuminates cancer stem cells
> Just over one year ago, we launched the pilot phase of an animation project titled StemCellShorts here on Signals blog. Funded by a Stem Cell Network Public Outreach Award, the project was very much an experiment for us to see what would happen when you tasked a team of talented creatives, expert faculty and...Read more

October 23, 2014

1:04 PM | The GFP That Blinked Sent W.E. Moerner On a Path from Physics to Cell Biology and on to a Nobel in Chemistry
Winners of a Nobel Prize typically get a private call from a member of the selection committee shortly before the news breaks to the public. But this year the Nobel committee couldn't reach W.E. Moerner, a professor of chemistry at Stanford University and an ASCB member. Moerner was in Recife, Brazil, on the morning of October 8, attending the Third International Workshop on Fundamentals of Light-Matter Interactions. Moerner had his cell phone turned off to save international roaming charges. […]

October 22, 2014

7:06 PM | Clot dissolver tPA’s tardy twin could aid in stroke recovery
Tissue-type plasminogen activator, meet urokinase-type plasminogen activator. You guys probably know each other. The post Clot dissolver tPA’s tardy twin could aid in stroke recovery appeared first on Lab Land.
4:22 PM | Why is Ebola so scary?
Unless you've been living under a reasonably sizable rock for the last few months, it can't have escaped your attention that the world has yet another terror to throw on the mountain of things we should be scared of: Ebola. The ongoing situation in Africa is the largest Ebola outbreak in history and has seen the disease spread beyond Africa for the first time. At the time of writing this, nearly 10,000 people have become infected, almost half of whom have died. This number is […]
1:22 PM | From Campus DJ to Kaluza Prize Winner, Josie Clowney Connects to Science
To be clear, E. Josephine Clowney, the 2014 winner of the $5,000 ASCB Kaluza Prize supported by Beckman Coulter, says she met her husband and learned to be a good scientist as a disc jockey for her college radio station. Leaving the husband part aside, Clowney explains the scientist part this way—playing all kinds of music on the highly eclectic WCBN-FM at the University of Michigan (UMich) in Ann Arbor, including music she didn't think at first was music, such as a Thai elephant […]

October 20, 2014

3:41 PM | What not to miss at #TMM2014
> Next week, close to 500 researchers, clinicians, trainees, industry and government representatives will gather in Ottawa for some of the best the stem cell and regenerative medicine research community has to offer. The third Till & McCulloch Meetings is taking place over three days, October 27-29 and we’re going with the theme of three...Read more
2:20 PM | Moral Time: Does Our Internal Clock Influence Moral Judgments?
Does morality depend on the time of the day? The study "The Morning Morality Effect: The Influence of Time of Day on Unethical Behavior" published in October of 2013 by Maryam Kouchaki and Isaac Smith suggested that people are more honest in the mornings, and that their ability to resist the temptation of lying and cheating wears off as the day progresses. In a series of experiments, Kouchaki and Smith found that moral awareness and self-control in their study subjects decreased... Read […]

October 19, 2014

12:09 PM | Ebola- Face The Fear
Ebola, the emerging threat from Africa, is without doubt a lethal killer. This serious threat has a grossly high mortality rate; the fatality rate for Ebola’s haemorrhagic fever (now known […]

October 17, 2014

12:35 PM | Right Turn: “Of all the senses, sight must be the most delightful”
. I don’t disagree with that quote by educator and humanitarian Helen Keller, a woman who overcame her inability to see, hear and speak, and graduated from college in 1904. However, I’m extremely squeamish when it comes to eyes. Perhaps it started in grade 8 science class when we had to dissect a cow’s eye…?...Read more

October 15, 2014

8:06 AM | Evolutionary Theories of Obesity
Obesity, evolution, medicine, theories, population, genetics, genome
4:00 AM | Laugh in the Face of Deadlines! Write That Research Paper with a Smile on Your Face!
Your latest western blot may be worth a thousand words but you will need to write1,000 words to go along with it. So how to choose which 1,000? To help with the essential task of writing up your latest research, we found some free advice (which will offset the cost of “free” open access publishing). ASCB photoYour latest western blot may be worth a thousand words but you will need to write1,000 words to go along with it. So how to choose which 1,000? To help with the essential […]

October 14, 2014

6:08 PM | Revisiting landmark folate-autism study
Geneticist Joe Cubells is re-examining a Chinese study of folic acid supplementation and its impact on autism risk The post Revisiting landmark folate-autism study appeared first on Lab Land.
1:09 PM | Update from the Clinic: September
. Welcome to your Update from the Clinic for the month of September. There’s a mixture of news from the cancer stem cell companies and immunotherapy companies this past month. Amongst other things, the FDA removed the previously imposed partial hold on one of OncoMed’s therapeutics; Opexa Therapeutics announced its next therapeutic program; and, Harvard...Read more
1:00 PM | New iBiology Videos Explore the Link Between Discovery and Medicine
"Interest in biology has never been higher,” says Louis Reichardt, emeritus professor of physiology at University of California, San Francisco (UCSF). And yet, as federal research funding declines, Reichardt worries that many graduate students are despairing of their prospects for productive research careers. “It takes some ingenuity now to find future opportunities in science,” he says. In recent years, Reichardt has devoted his own ingenuity to helping students find these […]

October 12, 2014

10:22 PM | The Psychology of Procrastination: How We Create Categories of the Future
"Do not put your work off till tomorrow and the day after; for a sluggish worker does not fill his barn, nor one who puts off his work: industry makes work go well, but a man who puts off work is always at hand-grips with ruin."        Hesiod in "The Works and Days" Paying bills, filling out forms, completing class assignments or submitting grant proposals – we all have the tendency to procrastinate. We may engage in trivial activities... Read more
2:02 AM | The most promising treatments for ebola are based on basic immunology-part 2
One of the more peculiar, historic and almost cinematic treatments being discussed in the midst of the ebola crises is the use of blood transfusions. In movies, the blood of a survivor or someone special is often supposed to have some sort of mystical effect on the (usually villainous) recipient. It turns out, blood transfusions […]

October 10, 2014

2:05 PM | Need a really small number?
Then you can use DNA origami. Ask Yonggang Ke in biomedical engineering for advice. The post Need a really small number? appeared first on Lab Land.
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