Posts

September 13, 2014

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4:00 AM | Black Pee Disease Offers New View of Arthritic Joints
When I read the headline of a recent press release – "A new cause of osteoarthritis identified by research on a rare disease" -- I was drawn to "rare disease," even though I actually have osteoarthritis. And when I read “alkaptonuria," I was catapulted back more than a century to the first description of an "inborn error of metabolism.”

September 12, 2014

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6:24 PM | One mother’s crusade against antibiotics–it’s complicated
This is a guest post by Karen Ernst, who is the parent-leader of Voices for Vaccines, a parent-led organization that supports and advocates for on-time vaccination and the reduction of vaccine-preventable disease. Karen is the mother of three boys and the wife of a military officer, living in Minnesota.  I could be the mother-in-charge of the such the […]Continue reading «One mother's crusade against antibiotics–it's complicated»
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6:09 PM | Back to School Biotech Reading List
Genetics and decision-making in drug discovery Part 1: overview ANDDecision-making part 2: Genetics and assays for drug discoveryRobert Plenge (Plenge Lab blog)Biotech's recent examples of why turnover can be an ominous signBrad Loncar (Loncar blog) $ACRX $KINMaking clinical development more investable with “financially adaptive trials”Frank David (Pharmagellan)The Transformation: Is it possible to control cancer without killing it?Jerome Groopman (The New Yorker) […]
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2:44 PM | How could I build a flying bicycle?
On a sunny afternoon in July of 2008, I decided to join other residents of Tang Hall to a building barbecue. This seemed like a great opportunity to get some free food and meet some interesting people. But it was far more than that. It was probably the most marking moment of my stay as […]How could I build a flying bicycle?
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2:43 PM | DNA Reveals the Identity of Jack the Ripper?
In the late 1800s, Victorian England was mesmerized and horrified by a series of brutal killings in the crowded and impoverished Whitechapel district. The serial killer, who became known as “Jack the Ripper”, had murdered and mutilated at least five women, many of whom worked as prostitutes in the slums around London. None of these […]
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1:37 PM | Merck Serono pulls development of lung cancer prospect
Ditches tecemotide immunotherapy to focus on anti-PD1
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1:18 PM | Friday SNPpets
Welcome to our Friday feature link collection: SNPpets. During the week we come across a lot of links and reads that we think are interesting, but don’t make it to a blog post. Here they are for your enjoyment… RT @wejlab: Our PathoScope 2.0 paper is now published online! http://t.co/1wn0fCzgJK @BU_CBM @BUbioinfo RT @rnomics: Pegasus: […]
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12:33 PM | Right Turn: Super Cells takes flight
> Those of you who’ve been following this blog regularly will know that we were in the process of building a science exhibit — we’ve published a few teasers, here and here. This week, Super Cells: The power of stem cells was unveiled in the small, historic city of Sherbrooke, Québec (well worth a visit,...Read more
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10:50 AM | FDA panel backs Novo Nordisk's liraglutide for obesity
Committee says diabetes drug could be used to reduce weight
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10:25 AM | AbbVie-partnered Calico unveils first licensing deal
Google’s healthcare research business gains rights to drug prospects in neurodegeneration
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9:26 AM | Pre-chemotherapy indication for Xtandi in prostate cancer
Astellas drug set to compete with J&J’s Zytiga
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8:55 AM | C. Elegans Rap!
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September 11, 2014

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11:15 PM | Gopa Mitra retires from PAGB
She steps down after 34 years at organisation
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11:07 PM | Mumps vaccine effectiveness and waning immunity
In a previous article, from our vaccine legal expert, Dorit Reiss, we learned that there’s a whistleblower lawsuit against Merck regarding the possibility that the company may have engaged in some inappropriate actions in determining the effectiveness of the MMR vaccine (for mumps, measles and rubella), specifically the mumps component of the vaccine. As Reiss stated, […]Continue reading «Mumps vaccine effectiveness and waning immunity»
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11:02 PM | The definition of value
Aligning the thoughts of biopharma and other healthcare stakeholders
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11:02 PM | Dive in: gaining leadership in a therapeutic area
Gaining long-term leadership in a therapy area can be commercially invaluable
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9:23 PM | The anniversary of September 11–my personal experience
For a moment, I want to step away from my typically snarky commentary about things I see in the pseudoscience world. I want to talk about my own experiences on that day, which, in retrospect, ended up being a closer call than I ever wish to have. You see, on September 11, 2001, I was […]Continue reading «The anniversary of September 11–my personal experience»
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5:06 PM | FDA Issues Home Use Medical Device Guidance
The FDA has issued a new guidance document intended to clarify how medical device manufacturers should approach certain design decisions for products targeted for home use. ‘Design Considerations For Devices Intended for Home Use’ is the final version of the draft guidance initially published in early 2013, and while it does not add any new ... continue reading
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4:31 PM | Mylan buys US rights to blood clot drug
$300m deal to acquire Arixtra from South Africa’s Aspen
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2:02 PM | Second time lucky for Takeda’s obesity drug
FDA approves Contrave three years after initial rejection
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1:50 PM | Baxter names biopharma spin-off Baxalta
Will separate from medical technology business
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1:48 PM | Black Pee Disease Offers New View of Arthritic Joints
“A new cause of osteoarthritis identified by research on a rare disease,” ran the headline of a news release a few weeks ago. I was drawn to “rare disease,” even though I actually have osteoarthritis. When I read “alkaptonuria,” I was catapulted back more than a century to the first description of an “inborn error of metabolism.” The release announced a paper in the October Journal of Anatomy, which is behind a paywall.… […]
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1:37 PM | What’s The Answer? (gene essentiality)
Biostars is a site for asking, answering and discussing bioinformatics questions and issues. We are members of the community and find it very useful. Often questions and answers arise at Biostars that are germane to our readers (end users of genomics resources). Every Thursday we will be highlighting one of those items or discussions here […]
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1:29 PM | Lantus faces first biosimilar rival in Europe
Sanofi prepares for insulin challenge from Boehringer and Lilly
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1:15 PM | Regenerative Medicine Deal Review: August
. Welcome to your deal review for the month of August. As would be expected at the end of the summer news flow was modest, but Northwest Biotherapeutics kept things alive with a $17.5 million financing via convertible debt, while Gamida Cell announced a game-changing deal with a large Pharma partner that is placing its...Read more
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7:56 AM | Young blood cures aged hearts
Young blood can reverse age-related heart disease in mice. Maybe vampires had the right idea. As we age, the chance of developing heart disease gets much higher. Heart disease is the number one killer worldwide. Older people are much more likely to have thickened hearts with bigger cells, a process that is called hypertrophy. Hypertrophied […]
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5:41 AM | You Could Still Be Waiting
I owe a lot to this blog. This blog got me into science writing, from the first time I pitched the idea of writing about anything and everything science (but especially about science in popular culture) to Nature Blogs in 2010. Lucky for me, they accepted my pitch (I was at the time a slightly unfulfilled biomedical PhD student at WashU in St. Louis), and I've been blogging ever since. This blog guided me into a graduate degree in journalism. This blog helped... Read more

September 10, 2014

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11:32 PM | Liberation strengthens team with new member
Edward Mullin has been appointed as account coordinator
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11:32 PM | Pharma spent $342m on journal advertising in first half of 2014
J&J led spending and Invokana was most advertised brand
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11:31 PM | Bayer partners with Glamour on female empowerment
Campaign to support the contraception Skyla
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