Posts

December 12, 2014

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11:00 AM | Ebola vaccine halt 'a precaution' say researchers
Some patients have reported joint pains
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10:39 AM | Roche's early development head Richard Scheller to retire
Will be replaced by Michael Varney from the company's Genentech business
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10:15 AM | Novartis' Cosentyx beats Stelara in psoriasis study
Cosentyx achieved clearance in 70% of patients
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12:15 AM | A difficult journey
The pursuit of excellence in key account management

December 11, 2014

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10:00 PM | Gardasil prevents cancer–does not lead to risky sexual activity
There are really few ways to keep your children from contracting cancer. Make sure they don’t smoke. Keep them out of the sun. Watch their weight and maintain it at healthy levels. Don’t let them near radiation. And vaccinate them against human papillomavirus (HPV), which causes over 5% of the cancers world wide. Gardasil, which is now […]Continue reading «Gardasil prevents cancer–does not lead to risky sexual activity»
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8:20 PM | More powerful cancer-preventing Gardasil vaccine cleared by FDA
Genital human papillomavirus (HPV) is the most common sexually transmitted infection (STI) in the USA. There are more than 40 HPV sub-types that can infect the genital areas of males and females. Additionally, some HPV types can also infect the mouth and throat. HPV is generally transmitted from personal contact during vaginal, anal or oral sex. HPV is linked to cancers […]Continue reading «More powerful cancer-preventing Gardasil vaccine cleared by […]
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7:06 PM | A History of Birds, Crocodilians… and Dinosaurs
It appears that today, thanks to the power of whole genome analysis and as published in Science magazine, we gain a knowledge about the ancient history of birds as never before. “An international team of scientists has completed the largest whole genome study of a single class of animals to date. To map the tree of life for birds, the team sequenced, assembled and compared full genomes of 48 bird species representing all major branches of modern birds including ostrich,... Read more
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6:47 PM | A Misplaced Concern about an Apple
Apples growing in British Columbia As a consumer and as an agricultural scientist, I’m looking forward to the introduction of the Arctic® apple. It is possibly nearing approval by regulators in the US and Canada which could mean that supplies might finally be available in a few more years.  These apples could give consumers the possibility of buying apples that maintain their flavor, appearance and vitamin content after cutting, and which can also be used to make beautiful dried […]
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6:43 PM | Scoop You!
Tweet This Post
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4:35 PM | Cancer Drugs Fund is not NICE replacement
Malcolm Qualie, pharmacy lead for specialised services within NHS England, speaks to PMLiVE
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4:00 PM | Plastics and the Epigenome
In recent years, there has been growing concern regarding the negative effects of compounds found in plastic products. BPA, the most widely publicized, is only one of many compounds, known to be endocrine disruptors, which are used in plastics. Exposure to endocrine disrupting chemicals has been linked to many diseases ... The post Plastics and the Epigenome appeared first on EpiBeat.
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2:39 PM | What’s the Answer? (tidy data format)
Biostars is a site for asking, answering and discussing bioinformatics questions and issues. We are members of the community and find it very useful. Often questions and answers arise at Biostars that are germane to our readers (end users of genomics resources). Every Thursday we will be highlighting one of those items or discussions here […]

Wickham H.W. (2014). Tidy Data, Journal of Statistical Software, 59 (10) Other:

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1:36 PM | Sequencing Kids’ Exomes: More Good News
“Exome” hasn’t yet entered the normal lexicon, like genome has. Yesterday, for example, I wore my clinical exome T-shirt from Ambry Genetics to Zumba class, and a woman came up and peered at my chest. “What the heck is that? What … Continue reading »The post Sequencing Kids’ Exomes: More Good News appeared first on DNA Science Blog.
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1:10 PM | The value of a cure
. With contributions from David Brindley. We recently discussed the role that consortia could play in accelerating the timeline of discovering and implementing new treatments, covering the ‘partnering’ aspect of the ‘Partnering for Cures’ conference held in New York City that was referenced. It, therefore, seems appropriate to devote some time to the ‘other half:’...Read more
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12:55 PM | Is your protein sumoylated? Top tips to improve your SUMO IPs.
Sumoylation of proteins has been associated with a whole host of cellular processes; transcription, replication, DNA repair, RNA metabolism, translation and transport and consequently interest in this modification is growing. Sumoylation of proteins usually occurs through binding of this moiety to lysine residues within the target protein or through non-covalent interactions. Four Sumo paralogues haveRead More
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12:19 PM | Studio: sviluppata pelle sintetica capace di avvertire temperatura e pressione
Da sempre per i portatori di protesi alla mano, la possibilità di avvertire il calore o il freddo è stato un desiderio impossibile da realizzare. Ma forse le cose stanno cambiando, grazie alla ricerca condotta dall’università coreana di Seul. Lo…Read more →
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11:18 AM | Opdivo to be tested as 'double immunotherapy' for tumours
BMS and Ono to test anti-PD-1 in combination with Kyowa Hakko's mogamulizumab
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11:13 AM | Merck to start major trial of Keytruda in breast cancer
PD-1 immunotherapy is already available as treatment for melanoma
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10:51 AM | Antibiotic resistance to lead to millions of deaths
UK publishes first progress report for antimicrobial resistance strategy
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12:17 AM | Kim Lemon appointed head of Liberation Unlimited
Will lead rebrand of Communiqué award-winning agency
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12:16 AM | Paolo Casati named as general manager of Santen Italy
Has over 30 years of experience in the sector
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12:16 AM | Cello Health acquires market research firm Promedica
Move is the group’s second acquisition of the year
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12:15 AM | Alzheimer’s charity launches £20m trials fund
Aims to fast-track research into dementia treatments
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12:00 AM | Don't forget email in your marketing strategy
Could it be the most underrated marketing channel in pharma?

December 10, 2014

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4:42 PM | Pfizer taps mobile app for patient recruitment
Looks to use smartphone technology to identify rare disease patients
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3:52 PM | A feminist mother and science advocate’s response to Vani Hari, the “Food Babe”
Originally published on the Genetic Literacy Project. Vani Hari, better known as “Food Babe,” is a self-proclaimed investigator of food and consumer advocate. Yet, some of her so-called investigations have been based in little to no evidence, while most of the rest of her claims are outright drivel. She has made her mark in an all-too-easy exploitation of public fear of the “unnatural,” distrust of establishment and love for fads. As expected, her opposition has been […]
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3:24 PM | Mass Spectrometry Application: Antibody Quantitation for Preclinical PK studies
Therapeutic monoclonal antibodies (mAbs) represent the majority of therapeutics biologics now on the market, with more than 20 mAbs approved as drugs (1–3). During preclinical development of therapeutic antibodies, multiple variants of each antibody are assessed for pharmacokinetic (PK) characteristics across model systems such as rodents, beagles and  primates. Ligand-binding assays (LBA) are the standard technology used to […]
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2:38 PM | Video Tip of the Week: “Virtually Immune” computational immune system modeling
This week’s video tip of the week is the next in a series. It began when I took a look at GeneFriends, and their option to output the data for use in BioLayout Express3D. So of course we had to then take a look at BioLayout. While I was exploring BioLayout, I came across Virtually […]

Enright, A. & Ouzounis, C. (2001). BioLayout--an automatic graph layout algorithm for similarity visualization, Bioinformatics, 17 (9) 853-854. DOI: 10.1093/bioinformatics/17.9.853

Theocharidis A., Anton J Enright & Tom C Freeman (2009). Network visualization and analysis of gene expression data using BioLayout Express3D, Nature Protocols, 4 (10) 1535-1550. DOI: http://dx.doi.org/10.1038/nprot.2009.177

Wright D.W., Anton J. Enright & Tom C. Freeman (2014). Visualisation of BioPAX Networks using BioLayout Express3D, F1000Research, DOI: http://dx.doi.org/10.12688/f1000research.5499.1

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2:29 PM | New Technique for Unprecedentedly Detailed Images of Mouse Neurons
Scientists can now explore nerves in mice in much greater detail than ever before, thanks to an approach developed by scientists at the European Molecular Biology Laboratory (EMBL) in Monterotondo, Italy. The work, published online today in Nature Methods, enables researchers to easily use artificial tags, broadening the range of what they can study and […]
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12:59 PM | UK Labour party pledges £330m cancer fund
Says will improve access to cancer drugs, radiotherapy and surgery if elected
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