Posts

September 11, 2014

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11:15 PM | Gopa Mitra retires from PAGB
She steps down after 34 years at organisation
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11:07 PM | Mumps vaccine effectiveness and waning immunity
In a previous article, from our vaccine legal expert, Dorit Reiss, we learned that there’s a whistleblower lawsuit against Merck regarding the possibility that the company may have engaged in some inappropriate actions in determining the effectiveness of the MMR vaccine (for mumps, measles and rubella), specifically the mumps component of the vaccine. As Reiss stated, […]Continue reading «Mumps vaccine effectiveness and waning immunity»
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11:02 PM | The definition of value
Aligning the thoughts of biopharma and other healthcare stakeholders
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11:02 PM | Dive in: gaining leadership in a therapeutic area
Gaining long-term leadership in a therapy area can be commercially invaluable
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9:23 PM | The anniversary of September 11–my personal experience
For a moment, I want to step away from my typically snarky commentary about things I see in the pseudoscience world. I want to talk about my own experiences on that day, which, in retrospect, ended up being a closer call than I ever wish to have. You see, on September 11, 2001, I was […]Continue reading «The anniversary of September 11–my personal experience»
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5:06 PM | FDA Issues Home Use Medical Device Guidance
The FDA has issued a new guidance document intended to clarify how medical device manufacturers should approach certain design decisions for products targeted for home use. ‘Design Considerations For Devices Intended for Home Use’ is the final version of the draft guidance initially published in early 2013, and while it does not add any new ... continue reading
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4:31 PM | Mylan buys US rights to blood clot drug
$300m deal to acquire Arixtra from South Africa’s Aspen
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2:02 PM | Second time lucky for Takeda’s obesity drug
FDA approves Contrave three years after initial rejection
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1:50 PM | Baxter names biopharma spin-off Baxalta
Will separate from medical technology business
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1:48 PM | Black Pee Disease Offers New View of Arthritic Joints
“A new cause of osteoarthritis identified by research on a rare disease,” ran the headline of a news release a few weeks ago. I was drawn to “rare disease,” even though I actually have osteoarthritis. When I read “alkaptonuria,” I was catapulted back more than a century to the first description of an “inborn error of metabolism.” The release announced a paper in the October Journal of Anatomy, which is behind a paywall.… […]
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1:37 PM | What’s The Answer? (gene essentiality)
Biostars is a site for asking, answering and discussing bioinformatics questions and issues. We are members of the community and find it very useful. Often questions and answers arise at Biostars that are germane to our readers (end users of genomics resources). Every Thursday we will be highlighting one of those items or discussions here […]
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1:29 PM | Lantus faces first biosimilar rival in Europe
Sanofi prepares for insulin challenge from Boehringer and Lilly
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1:15 PM | Regenerative Medicine Deal Review: August
. Welcome to your deal review for the month of August. As would be expected at the end of the summer news flow was modest, but Northwest Biotherapeutics kept things alive with a $17.5 million financing via convertible debt, while Gamida Cell announced a game-changing deal with a large Pharma partner that is placing its...Read more
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7:56 AM | Young blood cures aged hearts
Young blood can reverse age-related heart disease in mice. Maybe vampires had the right idea. As we age, the chance of developing heart disease gets much higher. Heart disease is the number one killer worldwide. Older people are much more likely to have thickened hearts with bigger cells, a process that is called hypertrophy. Hypertrophied […]
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5:41 AM | You Could Still Be Waiting
I owe a lot to this blog. This blog got me into science writing, from the first time I pitched the idea of writing about anything and everything science (but especially about science in popular culture) to Nature Blogs in 2010. Lucky for me, they accepted my pitch (I was at the time a slightly unfulfilled biomedical PhD student at WashU in St. Louis), and I've been blogging ever since. This blog guided me into a graduate degree in journalism. This blog helped... Read more

September 10, 2014

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11:32 PM | Liberation strengthens team with new member
Edward Mullin has been appointed as account coordinator
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11:32 PM | Pharma spent $342m on journal advertising in first half of 2014
J&J led spending and Invokana was most advertised brand
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11:31 PM | Bayer partners with Glamour on female empowerment
Campaign to support the contraception Skyla
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11:03 PM | Pharma deals during August 2014
Deal Watch: Major pharma collaborations, acquisitions and agreements in the past month
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11:02 PM | Deal Watch table for August 2014
Table listing all the major pharma mergers, acquisitions and collaborations in the past month
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7:46 PM | Merck, Mumps, Motions, Whistleblowers–the actual story
This article was written by Dorit Rubinstein Reiss, Professor of Law at the University of California Hastings College of the Law in San Francisco, CA. Dr. Reiss writes extensively in law journals about the social and legal policies of vaccination. She is also member of the Parent Advisory Board of Voices for Vaccines, a parent-led organization that supports and advocates for on-time vaccination […]Continue reading «Merck, Mumps, Motions, […]
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7:12 PM | Important Insight Into GPCR Signal Transduction Discovered
G protein-coupled receptors (GPCRs) are the largest class of cell surface receptors in our cells, involved in signal transmission across the cell membrane. One of the biggest questions is how a signal recognized at the extracellular side of a GPCR induces a sequence of conformational changes in the protein and finally evokes an intracellular response. […]
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4:00 PM | Oxidative Stress and Epigenetics: a Novel Link Established Through Histone Adduction
Damage to cellular macromolecules caused by reactive oxygen species (ROS) produced during oxidative stress contributes to the pathogenesis of many disease states. One target of ROS is the 1,4-diene structure of polyunsaturated fatty acids (PUFAs), which is highly susceptible to peroxidation. An important outcome of lipid peroxidation is the generation ... The post Oxidative Stress and Epigenetics: a Novel Link Established Through Histone Adduction appeared first on EpiBeat.
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2:48 PM | Fold It Up and Discover a Whole New World
Scientific inquiry —looking at the world and asking questions about what we observe—is a natural human behavior. Why is the sky blue? What would happen if I did this Mom? Ask any grade school teacher. Kids do science naturally. They are not afraid of questions. They are not afraid of nature. They are not afraid of […]
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1:36 PM | Video Tip of the Week: #Docker, shipping containers for software and data
Breaking into the zeitgeist recently, Docker popped into my sphere from several disparate sources. Seems to me that this is a potential problem-solver for some of the reproducibility and sharing dramas that we have been wrestling with in genomics. Sharing of data sets and versions of analysis software is being tackled in a number of […]

Baggerly K. (2010). Disclose all data in publications, Nature, 467 (7314) 401-401. DOI: http://dx.doi.org/10.1038/467401b

Citation
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11:42 AM | FDA panel votes against Actavis hypertension combo
Places a question mark over the combination of Bystolic and Diovan
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10:02 AM | NICE wants greater access to clinical data
Will turn to European regulators if companies fail to provide information
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9:56 AM | UK wants pharmacists to support better use of drugs
Lord Howe says current procedures are flawed and community pharmacy can help
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9:55 AM | Liraglutide seems effective in obesity, says FDA reviewer
Novo Nordisk drug is already successful diabetes treatment
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9:51 AM | Questions raised about affordability of asthma antibodies
Positive data on GSK and Teva anti-IL-5 candidates at ERS congress highlights cost concerns
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