Posts

March 02, 2015

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11:12 AM | Amgen's Kyprolis tops Velcade in myeloma trial
Amgen hoping to topple Takeda’s $2bn a year drug
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10:47 AM | Does 'trust leadership' feature in your strategy?
Pharma companies wanting to be more patient-focused will need to develop their people skills
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10:40 AM | Sanofi’s Lantus follow-up nears European approval
Comes in the same week that the French firm’s great white hope gains FDA licence
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10:27 AM | Greater Manchester to control its share of the NHS budget
The north-west English region accounts for 5% of the country's health spending
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8:08 AM | DNA computers
DNA stores a massive amount of information inside the tiny nuclei of living cells. It encodes all the instructions needed to make every living creature on earth. Therefore, DNA forms the basis of the most complex computers that exist: humans. So it makes sense that we are trying to use DNA to make artificial computers. […]
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5:22 AM | How to Write a Dissertation without Going Nuts
A month and a half ago I started writing my dissertation. Data collection started about 10 months ago, and I was still deep in data analysis in January when I realized I was going to have to start writing as I was analyzing data in order to get this thing done in time. A draft will go to my chair on Friday! (Whoa.) What is a dissertation anyway? Google tells me it's "a long essay on a particular subject, especially one... Read more
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1:14 AM | Oncology Journal Watch
Enjoy the following collection of OPEN ACCESS journal articles from the world of cancer research and development. MET Amplification Status in Therapy-Naïve Adeno- and Squamous Cell Carcinomas of the Lung Schildhaus et al. Clinical Cancer Research. $ARQL ANG4043, a Novel Brain-Penetrant Peptide–mAb Conjugate, Is Efficacious against HER2-Positive Intracranial Tumors in Mice Regina et al. Molecular Cancer Therapeutics. (Angiochem) High HER2 Expression Correlates with Response to […]

March 01, 2015

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7:28 PM | Documents spur investigation of climate sceptic
Documents spur investigation of climate sceptic: climateadaptation:Questions raised about conflict-of-interest disclosures by Willie Soon.The Harvard-Smithsonian Center for Astrophysics (CfA) has launched an inquiry into one of its researchers, solar physicist and global warming sceptic Willie Soon, following the release of documents that detail research funds he and the institution received from the energy industry and a conservative foundation.Obtained by Greenpeace through a Freedom of […]
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7:18 PM | 8bitfuture:It’s official, you should drink more coffee.The US...
8bitfuture:It’s official, you should drink more coffee.The US Office of Disease Prevention and Health Promotion - which brings together the top healthcare panel in the US - has broken its silence on caffeine. The panel says that with no studies showing negative effects on caffeine consumption on health, and a number of positive associations, it can now recommend drinking between 3 -5 cups per day - well above the current average of around 1 cup per day.From their report:Currently, strong […]
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5:30 PM | billdomonkos: GIF: Bill Domonkos, 2014 (Photo: Karl August...
billdomonkos: GIF: Bill Domonkos, 2014 (Photo: Karl August Andersson) (Pendulum Animation, H. Christiaen)

February 28, 2015

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11:38 PM | AGBT 2015 review...sort of
Another fun year at AGBT in sunny Marco Island. There has been some good blog coverage this year, but not from me; I've been Tweeting instead @CIgenomics on #AGBT15, see what happened on Twitter.The UCSC Twitter trackBlog coverage: GenomeWeb were there for those who could not make it - thanks team GenomeWeb, see Here, and here. OmicsOmics: Keith had several posts (always worth reading)Genohub: day1, day2, day3 NextGenSeq: has a preview post and covers Craig Venter's and Gene Meyer's […]
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10:49 PM | Republicans just passed a bill forbidding scientists from advising the EPA on their own research
Republicans just passed a bill forbidding scientists from advising the EPA on their own research: climateadaptation:The “reform” measure makes room for industry-funded experts on the EPA’s advisory board.Expect much more shenanigans like this over the next several years - all because Democrats, young people, and the left failed to vote in the midterms. Good times.. ughhhhhhhhhhhhhhhhhhhhhhhhh…………And Michael, c’mon, the real problem […]
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10:41 PM | imadeit-davidjanes:"Microsoft AR" lol
imadeit-davidjanes:"Microsoft AR" lol
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10:31 PM | "Shhhh…. stay very still.”
"Shhhh…. stay very still.”
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10:30 PM | Illustrated timeline of anti-fun moral panics
Illustrated timeline of anti-fun moral panics: mostlysignssomeportents: Tor.com has republished a great chart from Bad for You: Exposing the War on Fun! The chart details the central thesis of the book: that “the long-standing campaign against fun” is a recurring story in which anxious, killjoy grownups make up stupid explanations for why the stuff their kids…Read the rest… I really enjoyed this, lends some perspective on nay-sayers nowadays, but I’d like […]
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5:30 PM | startalkradio:Teen Girls Take Swipe At World Hunger With Google...
startalkradio:Teen Girls Take Swipe At World Hunger With Google Science Fair Idea, Remind Us All To Dream BigThree teen girls from Ireland had an idea, and it was a big one. They believed they had found a way to boost cereal crop yields and could help solve the world’s hunger crisis. But the adults in their lives cast doubt on their vision. Their scheme wouldn’t work, they were told.Fortunately for us, the girls refused to be discouraged. They started conducting extensive research […]
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4:43 PM | Climate change brings new infectious diseases to farms, new urgency in breeding resistance
Several reports from researchers around the globe predict the emergence and spread of infectious diseases as the result of climate change. Some of these diseases are new; others are not but they’re showing up in new places creating a new threat for those areas. This unfortunate development has created a new urgency in genetically modifying farm plants and animals specifically for disease resistance. The search for disease-resistant livestock has been underway for many years since […]
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1:25 PM | Día Mundial de las Enfermedades Raras
28 Febrero 2015http://www.rarediseaseday.org/http://www.genomicseducation.hee.nhs.uk/supporting-patients-and-families-with-a-rare-disease/
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1:03 PM | Actions speak louder than words: dTALEs for gene activation in fundamental research
Quick update for anyone who’s been living in a cave for the last five years: technologies for easily programmable precision DNA targeting are available and ready to go. This started with the TALEs: modular repeat proteins with one repeat binding one base with sequence specificity determined reliably by a single residue in each repeat. Then […]

February 27, 2015

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6:45 PM | Biotech Tweets of the Week (February 23-27, 2015)
Another fast-paced week on the biotech Twitter stream. Catch up on all the highlights with the latest edition of the Biotech Tweets of the Week. Thanks as always to @23aloha for collecting most of these! [...]
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6:31 PM | "Last year Keurig produced 9.8 billion of their branded cups, up from 2013 when the figure was 8.3..."
“Last year Keurig produced 9.8 billion of their branded cups, up from 2013 when the figure was 8.3 billion. After years of non-biodegradable plastic K-Cups being discarded, there could be as many as 60 billion small plastic cups filling landfill sites across the world. Approximately 95% of the non-biodegradable K-Cups end up in landfill because they are made of No.7 plastic which is non-recyclable and it is estimated that in 2013, enough of the plastic cups were discarded to create a […]
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5:30 PM | kateoplis:"In America [alone] we discard over 146 billion cups...
kateoplis:"In America [alone] we discard over 146 billion cups from coffee consumption annually. Even when we think we are recycling and doing a good deed, the paper itself within these products can only be reused 2-3x before the fibers are unusable and discarded into local landfills without consumer’s knowing.We have developed a post consumer paper based cup which will be able to extract over 1 ton of CO2 out of the atmosphere annually once planted. We have taken those fibers from […]
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3:26 PM | Right Turn: A lesson in blood development
Hematopoiesis is a long word, but in essence it describes a pretty straight-forward concept: The formation of our blood system, including all of its components. It’s a multi-step process beginning with stem cells and ending with mature, specialized ones like red blood cells, white blood cells, lymphocytes and others. I won’t go into great detail...Read more
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3:08 PM | teded:The assumption that sadness has an external cause outside...
teded:The assumption that sadness has an external cause outside the self is a relatively new idea. Ancient Greek doctors didn’t view sadness that way. They believed it was a dark fluid inside the body. Melaincholia comes from melaina kole, the phrase for ‘black bile.’From the TED-Ed Lesson A brief history of melancholy - Courtney StephensAnimation by Sharon Colman Graham That’s probably why I got such a good sense of humor.
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2:48 PM | Jinarc recommended for European approval in rare kidney disease
Positive opinion for Otsuka comes just before rare disease awareness day
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2:48 PM | Jinarc backed for European approval in rare kidney disease
Positive opinion for Otsuka comes just before rare disease awareness day
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2:19 PM | Friday SNPpets
This week’s SNPpets include a new cancer Data Catalog from NCI, Avianbase for bird genomics, a couple of variant calling tools, and someone trying to genotype the color assessment of “the dress” using 23andme data. Heh. [But at least no llamas were harmed in the making of this post.] Welcome to our Friday feature link […]
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2:06 PM | UCB boosted by core medicines growth
Firm’s new chief executive 'excited' by his company’s next batch of medicines
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1:29 PM | Did You Ever Run Out of Reagent on a Weekend? Try Smart, On-Site Stocking
You know the scene: you are working on a key experiment on a weekend or after hours–finishing up before an upcoming meeting or before a grant update or proposal submission. You go to the laboratory freezer for that enzyme or protease, or worse to the shelf for the nucleic acid extraction kit for all those samples […]
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11:43 AM | BMS and Gilead antivirals cure hep C in co-infected HIV patients
Phase III trial cured 97% of patients
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