Posts

May 17, 2013

8:00 AM | Carbon Nanotubes – Laboratory to Industry

On Thursday May 9th Professor Alan Windle, FRS and Director of the Pfizer Institute for Pharmaceutical Materials Science, which is located in the Department of Materials Science & Metallurgy at the University of Cambridge, spoke about creating and exploiting carbon nanostructures in materials science. This talk was one of a number of science related events [...]The post Carbon Nanotubes – Laboratory to Industry appeared first on Oxbridge Biotech.

May 16, 2013

9:02 PM | Does Loss of DNA Methylation and Hydroxymethylation in the Brain Lead to Loss of Memory?

5-methylcytosine (5-mC) and 5-hydroxymethycytosine (5-hmC) are two major epigenetic modifications of DNA. Dynamic changes in 5-mC and 5-hmC levels are tightly regulated and impact neural cell development, differentiation, and other biological functions. Deregulation of 5-mC and 5-hmC has also been implicated in various human diseases. However, whether 5-mC and 5-hmC are involved in aging-related neurodegenerative ...

Chouliaras L, Mastroeni D, Delvaux E, Grover A, Kenis G, Hof PR, Steinbusch HW, Coleman PD, Rutten BP & van den Hove DL & (2013). Consistent decrease in global DNA methylation and hydroxymethylation in the hippocampus of Alzheimer's disease patients., Neurobiology of aging, PMID: 23582657

Mastroeni D, McKee A, Grover A, Rogers J & Coleman PD (2009). Epigenetic differences in cortical neurons from a pair of monozygotic twins discordant for Alzheimer's disease., PloS one, 4 (8) PMID: 19672297

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8:44 PM | Small words – Town Hall talk for Ignite Seattle

Some people in science like to use big words. You know what I’m talking about. Climatology, prehistoric, proteomics. Or phrases that tie us up in knots. I’m a fan of small ordinary words. Words that all of [More...]

1:37 PM | To the stars and beyond: Assessing the impact of the $100 Genome

We live in a time of extraordinary medical advances. So far in 2013, we’ve seen the successful transplantation of a bioengineered kidney into rats, an infant reportedly cured of HIV using anti-retroviral drugs that are currently on the market, and discovered a protein that has the potential to ‘reverse aging’ in the heart. These ‘small...Read more

1:02 PM | What’s the Answer? (unglamorous tasks)

BioStar is a site for asking, answering and discussing bioinformatics questions and issues. We are members of the community and find it very useful. Often questions and answers arise at BioStar that are germane to our readers (end users of genomics resources). Every Thursday we will be highlighting one of those items or discussions here [...]

10:12 AM | A Little Girl With Giant Axons, a Deranged Cytoskeleton, and Someday Gene Therapy

9:00 AM | A Fun FRET Follow Up

Some fun to follow up with yesterday’s explanation of FRET. Tweet This Post

4:00 AM | A Little Girl with Giant Axons, a Deranged Cytoskeleton, and Someday Gene Therapy

“When you hear hoof beats, think horses, not zebras.” So goes the mantra of first-year medical students. If a common disease is a horse and a rare disease a zebra, then giant axonal neuropathy (GAN), with only 50 or so recognized cases worldwide, is surely a unicorn. Five years ago this week, 9-year-old Hannah Sames of Rexford, New York, who lives near me, received a diagnosis of GAN, a disease much like amyotrophic lateral sclerosis. And this month, thanks in part to the herculean […]

3:53 AM | Base Space- Open for Business!

Today marks the commercial availability of BaseSpace, including the fully supported and intuitive BaseSpace App Store for quick and easy access to Illumina and third-party bioinformatics applications. Check out the detailed post in the BaseSpace blog, to learn more about three new apps from Omixon, Elsevier, and PicardSpace, as well as the new ISAAC alignment and variant calling app. We’re also debuting the Public Data tab, making it easy to locate example datasets and match them to the right […]

3:52 AM | OBR London: Therapeutic use of monoclonal antibodies and future trends in biotherapeutics

By Kiran Nandra, OBR-London Correspondent LONDON, United Kingdom – OBR hosted an event on Tuesday 7th May at Queen Mary University of London, to discuss the therapeutic use of monoclonal antibodies and future trends in biotherapeutics with some of the industry’s experts. OBR were honoured to be joined by Dr Steve Holmes, Director of Therapeutic [...]The post OBR London: Therapeutic use of monoclonal antibodies and future trends in biotherapeutics appeared first on Oxbridge Biotech.

2:22 AM | What are you an expert in?

Have you ever read an article, attended a panel discussion, or watched a tv show and thought: “I really wish they’d featured an expert” ? I can’t say if it’s intentional or unintentional, but there definitely seem to be many cases where a panel discussing aspects of agriculture consists of representatives from EWG, UCS, CFS, etc and there might, if we are really lucky, be one person who has some understanding of the science. One example is of this is an episode […]

12:15 AM | Plant Science Already Feeling Sequester’s Pain

The sweeping cuts in federal spending known as the sequester are already taking a toll on scientific research. Jennifer Fletcher, a professor at the University of California, Berkley stationed at the USDA-funded Plant Gene Expression Center, faces the sudden challenge of slashing direct research costs by 40%. “I’m paying part of a research associate’s salary… and already as a result of the cuts we’ve had to eliminate that position.” Now Fletcher has less money to spend on supplies […]

May 15, 2013

11:54 PM | Agriculture Phrases that Frustrate Me

Everywhere I go, I hear farmers argue over the word ‘sustainable’. So much so, that I really want to puke. It gets brought up at policy meetings, on social media sites, and in blog entries. When I hear farmers discussing what it means, I only hear Charlie Brown’s teacher… wha wha wha wha whaa, wha wha wha wha whaaa. What brought on this latest episode of word fatigue? Yet another article written that only serves to divide farmers into groups. Organic vs conventional, small vs large. […]

9:47 PM | Explain Your Experiments Using Animation

For visual learners, nothing is more frustrating than verbal insructions that are not accompanied by visual queues. Scientific experiments often involve detailed instructions that may be tedious and hard to follow. It is important for scientists to convey the “big picture” of what they are tryiing to accomplish in order for their work to be [...]

4:36 PM | Apple Activists vs Scientists

At the 2013 Biotechnology Industry Organization (BIO) Conference, I had the unique opportunity to meet and interview Neal Carter, President of Okanagan Specialty Fruits, makers of the Arctic® Apple, and also attend a protest of the same apple organized by the Organic Consumers Association. I interviewed Mike Durshmid who was leading the protest, and asked him a number of questions. Both full interviews will be up and available soon, along with more footage of the protest, but now I have a […]

2:54 PM | Optimizing a DNA Methylation Analysis Workflow

When Aristotle compared epigenetics to a net (1), he could not have predicted how right he was. Recent research has revealed that mechanisms underlying epigenetic effects are numerous and interdependent as are the knots in a net. Each epigenetic mechanism has its players: enzymes, functional groups, substrates etc. The most important aspect of an epigenetic […]

2:35 PM | CRUING PREMIATA A PARIGI CON IL JEC EUROPE INNOVATION AWARD 2013

L’azienda italiana ha ricevuto il prestigioso riconoscimento, assieme a BMW, PEUGEOT e CITROEN, per il suo Aerotech, il sistema che elimina le particelle calde di polvere prodotte durante il taglio. Con tre parole d’ordine: salute, ambiente e risparmio Il Bel Paese ha un primato nell’innovazione tecnologica. E il successo porta la firma della [...]

2:21 PM | IL 3D PRINTING PROTAGONISTA DI EUROLUCE 2013 GRANDE SUCCESSO PER .EXNOVO, PER LA PRIMA VOLTA IN MOSTRA AL SALONE INTERNAZIONALE DEL MOBILE

Le innovative lampade di .exnovo, giovane marchio trentino specializzato nella produzione di esclusivi elementi di design – illuminazione, arredo, oggettistica - prodotti attraverso tecnologie di Professional 3D Printing, sono state molto apprezzate dal variegato pubblico del Salone del Mobile, Fiera Milano-Rho. Per la prima volta in mostra ad Euroluce, il punto di riferimento mondiale dedicato al settore [...]

2:19 PM | Background Survival of Transgenic Mouse Models of Alzheimer’s Disease – SOT 2013

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2:00 PM | Using stem cells to cure… extinction?

In last week’s Right Turn, we talked about how stem cells are responsible for the colours and patterns of bird feathers—and birds, as the graphic on the right demonstrates, are basically just tiny dinosaurs. Given that there is much promise in stem cell research (and also a great deal of hype), it makes one wonder:...Read more

Friedrich Ben-Nun I., Montague S.C., Houck M.L., Tran H.T., Garitaonandia I., Leonardo T.R., Wang Y.C., Charter S.J., Laurent L.C. & Ryder O.A. & (2011). Induced pluripotent stem cells from highly endangered species, Nature Methods, 8 (10) 829-831. DOI: 10.1038/nmeth.1706

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1:33 PM | Video Tip of the Week: Influenza Research Database (IRD)

It may not be traditionally what you think of as flu season, but lately there’s been a great deal of talk about some viruses that are concerning public health officials and infectious disease specialists. You might have heard of the H7N9 situation in China, and the NCoV virus in France that made headlines. But researchers [...]

Squires, R., Noronha, J., Hunt, V., García-Sastre, A., Macken, C., Baumgarth, N., Suarez, D., Pickett, B., Zhang, Y., Larsen, C. & Ramsey, A. (2012). Influenza Research Database: an integrated bioinformatics resource for influenza research and surveillance, Influenza and Other Respiratory Viruses, 6 (6) 404-416. DOI: 10.1111/j.1750-2659.2011.00331.x

Pickett, B., Sadat, E., Zhang, Y., Noronha, J., Squires, R., Hunt, V., Liu, M., Kumar, S., Zaremba, S., Gu, Z. & Zhou, L. (2011). ViPR: an open bioinformatics database and analysis resource for virology research, Nucleic Acids Research, 40 (D1) DOI: 10.1093/nar/gkr859

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10:58 AM | Siemens e SABIC insieme svilupperanno una soluzione per la gestione dei dati energetici

La Divisione Smart Grid di Siemens e SABIC Polyolefine GmbH con sede in Gelsenkirchen hanno firmato un accordo di partnership per lo sviluppo di una soluzione per la gestione dei dati energetici nei settori industriali ad alto consumo di energia. L’obiettivo è migliorare i processi petrolchimici della Saudi Basic Industries Corporation con sede a Gelsenkirchen. [...]

10:44 AM | “On the Road to Innovation: Mobile Mapping System per il monitoraggio delle infrastrutture”: per conoscere da vicino le soluzioni di CAM2 e Siteco Informatica

Grugliasco (Torino), 29 aprile 2013 – CAM2 (Gruppo FARO Technologies, Inc. – NASDAQ: FARO), fornitore leader a livello mondiale di soluzioni portatili di misura e di imaging, e Siteco informatica, società italiana attiva a livello internazionale specializzata nella realizzazione di soluzioni e nella fornitura di servizi nell’ambito dei Sistemi Informativi Stradali, presentano l’evento “On the [...]

10:38 AM | Segui il tour dell’Energy Efficiency Truck di Siemens

• Prosegue l’itinerario europeo con le quattro tappe italiane • In 65m² le soluzioni per l’efficienza lungo l’intera catena del valore Dopo l’enorme successo riscontrato in Europa, lo showroom su quattro ruote di Siemens prosegue il suo tour con le quattro tappe italiane: Novara il 10 maggio, Padova il 14 maggio, Milano il 16 maggio [...]

10:33 AM | I Big Data delle risorse umane oggi sono a portata di click con Inaz Analytics

Inaz lancia la sua soluzione di business intelligence per le risorse umane: il capitale umano di un’azienda diventa analizzabile e navigabile con Inaz Analytics, il software che aiuta a monitorare le performance, a tenere sotto controllo i costi e a fare previsioni per decidere prima e meglio Il tema dei Big Data, l’ultima frontiera dell’IT [...]

10:30 AM | Eusebi Impianti, in volo verso la sfida del Kazakhstan

L’azienda marchigiana, leader nel settore dell’impiantistica antincendio e di sicurezza, ha acquisito una commessa da 12 mln di dollari dall’Agip KCO (Eni), nell’ambito del progetto Kashagan per l’estrazione di petrolio dal nuovo e ricchissimo giacimento kazakho. I primi impianti sono già partiti verso la meta tramite dei voli cargo Antonov dall’aeroporto di Montecchiari L’eccellenza [...]

10:23 AM | Superfluidità ad alta temperatura in dispositivi a base di grafene: un importante risultato dei Fisici Unicam

Camerino, 23 aprile 2013 – Un importante risultato dei fisici Unicam A ndrea Perali e David Neilson è stato pubblicato di recente dalla prestigiosa rivista scientifica Physical Review Letters. L’Editor della rivista ha selezionato il loro lavoro come il migliore del numero e lo ha segnalato ai lettori per l’interesse trasversale. I due docenti, in [...]

10:12 AM | VISIT MALTA SCEGLIE 4W MARKETPLACE PER LA PUBBLICITÀ CONTESTUALE E MOBILE

Milano, 22 aprile 2013 – Malta Tourism Authority (l’Ente del Turismo di Malta) lancia attraverso il network di 4w MarketPlace le campagne pubblicitarie per la promozione della destinazione Malta su mobile e web. Il sito istituzionale di MTA è www.visitmalta.com dove è possibile trovare contenuti ed eventi relativi alle tre isole Malta, Gozo e Comino. [...]

10:04 AM | Nuova maxi frode dei pallet a Forlì. Stop al commercio illegale dei pallet. Conlegno scende in campo a sostegno della legalità

A pochi giorni dalla scoperta di una nuova maxi frode sul commercio illegale di pallet in legno, Conlegno si schiera dalla parte della legalità e scende in campo a sostegno delle imprese che operano nel pieno rispetto delle normative, non solo per scongiurare gravi pericoli dal punto di vista fitosanitario e della sicurezza delle merci, [...]

9:57 AM | Una plastica geniale. La tecnologia Gloryfy unbreakable è unica al mondo

gloryfy G-Flex® e gloryfy I-Flex® sono i nomi di un materiale altamente elastico (lavorato in due modi diversi, per la montatura e per le lenti) che possiede una proprietà straordinaria: l’effetto memoria. Indipendentemente da quanto venga deformato, questo materiale sintetico permette all’occhiale di tornare sempre nella sua forma originale. Il fattore determinante è la combinazione [...]

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