Posts

October 08, 2014

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9:49 PM | This deadly viral epidemic frightens me
A deadly disease has entered the USA. And it took its first victim yesterday.(1) During the past 10 years, this disease has killed up to 49,000 Americans, annually, of all ages and demographic groups, annually.(2) On average, 250,000-500,000 people die from the disease every year.(3) During an average year, over 200,000 Americans are hospitalized for this viral […]Continue reading «This deadly viral epidemic frightens me »
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9:04 PM | Update–Polio-like illness (acute flaccid paralysis) in California
Earlier this year, I reported on an outbreak of a mysterious viral disease that exhibited polio-like symptoms. At the time, around 23 children and young adults were afflicted with the disease. Some of them tested positive for enterovirus-68, a member of a genus of viruses that include over 66 different species that can infect humans. None of them tested positive for the […]Continue reading «Update–Polio-like illness (acute flaccid paralysis) […]
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4:23 PM | Highlights from ISHI25
Last week (September 29–October 2), I was one of almost 1,000 people who attended the 25th International Symposium on Human Identification (ISHI25) in Phoenix, Arizona. This scientific meeting brings together DNA analysts from forensic and paternity labs, research scientists and others with an interest in DNA-based identification to learn about new technologies, policy and process […]
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2:51 PM | Premio Nobel medicina 2014 a chi ha scoperto il gps interno al nostro cervello
Sono John O’Keefe della University College di Londra, e i coniugi May‐Britt Moser ed Edvard I.Moser della Norwegian University of Science and Technology di Trondheim i vincitori del premio Nobel per la medicina e la fisiologia 2014, con cui a Stoccolma…Read more →
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2:14 PM | Premio Nobel Chimica 2014: premiata la microscopia fluorescente
A Stoccolma il premio nobel per la chimica 2014 è andato a Eric Betzig, Stefan W. Hell e William E. Moerne. I vincitori sono riusciti a creare un nuovo tipo di microscopia, molto più dettagliata rispetto a quelle attualmente esistenti.…Read more →
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2:04 PM | Premio Nobel fisica 2014: premio agli inventori dei led
La luce che ha illuminato il mondo. Così da Stoccolma il comitato che assegna il premio più ambito ha definito l'invenzione dei diodi a emissione di luce blu che ha cambiato la vita di tutti noi, oltre che permettere di utilizzare l'energia in modo meno invasivo Read more →
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10:49 AM | Video Tip of the Week: UCSC #Ebola Genome Portal
Although I had other tips in my queue already, over the last week I’ve seen a lot of talk about the new Ebola virus portal from the UCSC Genome Browser team. And it struck me that researchers who have worked primarily on viral sequences may not be as familiar with the functions of the UCSC […]

Karolchik D., G. P. Barber, J. Casper, H. Clawson, M. S. Cline, M. Diekhans, T. R. Dreszer, P. A. Fujita, L. Guruvadoo, M. Haeussler & R. A. Harte (2013). The UCSC Genome Browser database: 2014 update, Nucleic Acids Research, 42 (D1) D764-D770. DOI: http://dx.doi.org/10.1093/nar/gkt1168

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10:12 AM | NICE denies two drugs in new MS guidance
Sativex and Fampyra too costly for NHS in England
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10:00 AM | AZ launches breast cancer photo-sharing campaign
Social media campaign will see a selection of the pictures displayed in New York
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9:49 AM | BMS drops US application for 'breakthrough' hep C combination
Blames the 'rapidly evolving' market for asunaprevir withdrawal
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9:37 AM | Sanofi alerts US authorities over bribery allegations
Concerns raised by anonymous whistleblower
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9:19 AM | Wet-Lab Validated Real-Time PCR Assays for Rat Genome
Bio-Rad Laboratories has launched its new PrimePCR™ Rat Genome Assays for quantitative real-time PCR (qPCR) (available in U.S., Canada, Australia, New Zealand, Singapore, and E.U. only). This expands Bio-Rad’s line of wet-lab validated assays that includes human and mouse genome assays. Assay validation is one of the most important steps in qPCR but is sometimes […]
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9:18 AM | GSK unit takes new ofatumumab formulation into phase III
Studied in autoimmune disorder of the skin
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7:36 AM | Cattle Code Cracked in Detail
Media Release, Aarhus University, October 3, 2014. The cattle genome has now been mapped to a hitherto unknown degree of detail, constituting a quantum leap for research into the history and genetics of cattle. By creating a global database an international consortium of scientists has increased the detailed knowledge of the variation in the cattle genome by several orders of magnitude. The first generation of the new data resource, which will be open access, forms an essential tool for […]

October 07, 2014

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11:30 PM | CROS NT appoints Renee Covell as head of US operation
She brings over 20 years of experience to the contract research organisation
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11:02 PM | Turkey's pharma market is ripe for profitability
But will the highly efficient market be hindered by the government price referencing system?
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7:00 PM | So, speaking of research objects….
A very timely post, related to some of the things I was grousing about in my long software piece. A tremendously important post — read @pebourne on NIH Commons vision: http://t.co/88FS65w4AO — Titus Brown (@ctitusbrown) October 7, 2014
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3:58 PM | Count-down to AGBT 2015
Registration is open! The registration process for AGBT has been overhauled in the last few years; yes there's still a lot of people who don't get in, but it seems to be pretty fair. Countdown WidgetsI hope to see you there. I'm going to be blogging and Tweeting again (assuming I get in). Say Hi if you read CoreGenomics and I'll buy you a beer (or rather grab one from Illumina, Agilent, etc)!
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1:29 PM | IPHA names Janssen's Dr Leisha Daly as president
Has been vice president since 2012
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12:55 PM | Apple Bars Medical Device Apps From iCloud Data Storage Service
Data security is a common rallying point for medical device manufacturers, especially those brave enough to enter the churning medical device app space. The ability of major corporations to protect the data of their users was highlighted by a spate of well-publicized hacks, including illegal access to information held by Apple’s iCloud online storage system ... continue reading
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12:00 PM | Stem Cell Awareness Day: October 8, 2014
Tomorrow, Wednesday, October 8, is Stem Cell Awareness Day. It’s a day to celebrate stem cells, have discussions on what stem cell research is, and learn about potential benefits and disease treatments using stem cells. Many national and international events (especially in California) are taking place to celebrate this special day — the California Institute … Continue reading »
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10:59 AM | Cancer Drug Fund moves towards a price assessment role
NHS England consults on a series of changes to the way Fund works
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9:53 AM | Actavis buys infectious disease specialist Durata
Will acquire US-approved Dalvance as part of the deal
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9:15 AM | Teva scales back R&D as Copaxone competition looms
Copaxone accounts for almost 40% of its revenue

October 06, 2014

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11:07 PM | A Science Journalist’s Chances
Frank Nuijens, @FrankNu on Twitter, recently pinged me in a tweet featuring an infographic that one of his Masters of Science Communication students created after reading my EMBO Reports article on the future of science journalism, An Explosion of Alternatives. Intrigued, I got in touch with the student, Benjamin Mul, to ask if he could talk to me about his graphics, shown below. Frank is a science journalist and founder of ScienceOnline Leiden, the Dutch community of people communicating […]
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9:35 PM | Another flu vaccine myth–Big Pharma profits
The 2014-15 flu season is upon us, and that means it’s flu vaccine time again. Despite the availability of several flu vaccines, many people think that the flu is a painless, harmless disease, a belief belied by evidence. To put flu in perspective, in the USA, depending on the severity of the flu season, from 3,000 (which happened 25 years […]Continue reading «Another flu vaccine myth–Big Pharma profits»
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7:16 PM | The Sophisticated European Scientist
Another example of how European scientists are more sophisticated than their American counterparts. Tweet This Post
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3:18 PM | Bioinformatics tools extracted from a typical mammalian genome project [supplement]
This is Table 1 that accompanies the full blog post: Bioinformatics tools extracted from a typical mammalian genome project. See the main post for the details and explanation. The table is too long to keep in the post, but I wanted it to be web-searchable. A copy also resides at FigShare: http://dx.doi.org/10.6084/m9.figshare.1194867 Software tool/object/item/resource access […]

Carbone L., R. Alan Harris, Sante Gnerre, Krishna R. Veeramah, Belen Lorente-Galdos, John Huddleston, Thomas J. Meyer, Javier Herrero, Christian Roos, Bronwen Aken & Fabio Anaclerio (2014). Gibbon genome and the fast karyotype evolution of small apes, Nature, 513 (7517) 195-201. DOI: http://dx.doi.org/10.1038/nature13679

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3:12 PM | Bioinformatics tools extracted from a typical mammalian genome project
In this extended blog post, I describe my efforts to extract the information about bioinformatics-related items from a recent genome sequencing paper, and the larger issues this raises in the field. It’s long, and it’s something of a hybrid between a blog post and a paper format, just to give it some structure for my […]

Carbone L., R. Alan Harris, Sante Gnerre, Krishna R. Veeramah, Belen Lorente-Galdos, John Huddleston, Thomas J. Meyer, Javier Herrero, Christian Roos, Bronwen Aken & Fabio Anaclerio (2014). Gibbon genome and the fast karyotype evolution of small apes, Nature, 513 (7517) 195-201. DOI: http://dx.doi.org/10.1038/nature13679

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3:04 PM | Tasi e Tari 2014: ecco come si calcolano
La scadenza per il pagamento è tra pochi giorni: il 16 ottobre. Arriva la Tasi, la temibile imposta che colpirà presto non solo i proprietari di case, ma anche gli inquilini. Molti si interrogano ancora sui meccanismi alla base delle nuove…Read more →
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