Posts

August 08, 2014

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4:00 PM | The Mysterious Role of non-CpG Methylation in the Brain
DNA methylation is a key mechanism of epigenetic regulation of gene expression and contributes to a multitude of process such as embryonic development, cancer, aging and learning and memory. In the metazoan genome, CpG methylation is the primary form of DNA methylation and is therefore extensively studied. However, key questions ... The post The Mysterious Role of non-CpG Methylation in the Brain appeared first on EpiBeat.
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3:43 PM | New Job! And Other Changes
Now that I have an official start date, I can announce it properly: starting next Monday, I'll be a Science Writer for the National Renewable Energy Laboratory!(And yes, this does mean I moved across seven states--I'm still unpacking.)I'm so excited about this, everyone! I've done science professionally for a long time, and written about it on the side, but for a while I've been wanting to shift the proportions around a bit. Now I'll have a chance to do just that. This blog has been a big part […]
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3:15 PM | The Power and Potential of Next-Generation Sequencing
Next-generation sequencing (NGS), also known as massively parallel sequencing, is revolutionizing genomic research. NGS technologies have made whole genome sequencing fast and easy, leading to dramatic advances in evolutionary biology and phylogenetics, personalized medicine and forensic science. Why is NGS such a hot topic right now? While there are more than a dozen next-generation sequencing […]
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2:32 PM | University of Alberta to honour beef researcher
Next week the University of Alberta is honouring Dr. Roy Berg, a man who changed Alberta’s cattle industry, by re-naming the Kinsella Ranch after him. Berg conducted research at the ranch from 1960 to 1988. His research proved the value of hybrid vigour to the industry in a time when purebred herds were still the norm for commercial producers. He initially faced opposition, even scorn, from many in the industry, who christened his hybrid herd “Berg’s bastards” and […]
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1:30 PM | Right Turn: All about regeneration – navigating fact and fiction
. The following scene from Family Guy offers a glimpse into both the tone and subject matter of this week’s Right Turn. Being an avid lover of superheroes, monsters and all things supernatural, the topic of healing and limb regeneration has always been a subject I find vastly exciting. If you’re having trouble understanding what...Read more
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1:29 PM | Medical Device Industry News Video Roundup – July 2014
Welcome to the Aptiv Solutions medical device news roundup for July 2014! We’ve gathered ten news stories offering information that may just help your company prosper. Coming up in this roundup: the medical device sector continues to evolve across the globe and over a variety of medical conditions. Outsourcing specific aspects of medical device trials ... continue reading
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1:09 PM | Friday SNPpets
Welcome to our Friday feature link collection: SNPpets. During the week we come across a lot of links and reads that we think are interesting, but don’t make it to a blog post. Here they are for your enjoyment… RT @ryodejaneiro: Our dendrogram paper is published http://t.co/HIPXYdhIDn presented a poster on this project at #biovis […]
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11:16 AM | Pfizer closes on $1bn label expansion for Prevenar
EMA begins review of the pneumococcal vaccine
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11:14 AM | Baxter opens Advate facility in Singapore
Follows EU approval for haemophilia A drug plant
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10:53 AM | MS market set to grow 4% annually
Predicted to reach $20bn by 2023 partly due to Plegridy and ocrelizumab launches
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10:16 AM | EFPIA: The patient is at the heart of what we do
And we are at the heart of economic growth, says Richard Bergström

August 07, 2014

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11:15 PM | Roche blasts UK’s 'broken' HTA system as Kadcyla rejected
But NICE says it is 'very disappointed' with the company's pricing policy
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11:01 PM | Has the biological revolution in rheumatoid arthritis peaked?
In the short term the focus looks set to be on personalised use of existing therapies
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11:01 PM | emotive continues to grow
London digital agency appoints Aaron Joshua Barroso digital marketing manager
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11:00 PM | Janssen looks to NASCAR for atrial fibrillation awareness
Company's MyAFibStory.com 400 kicks off the NASCAR Sprint Cup series
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10:58 PM | The Worst Pain Known to Man… It’s a Stinger
A man stands ready, nervous but staunch. His face and hands are painted in warrior colors – black and red. Today, he will become a man. His initiation will be pain – pure, intense, brilliant pain. Walking over flaming charcoal with a nail in his heel pain. But his pain won’t come from fire, nor from a rusty nail. It won’t come from being attacked by a bull, a lion, or any other large, fierce creature. It won’t come from... Read more
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8:12 PM | How Animation Is Changing Biology
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8:02 PM | Chiropractic manipulation of neck may cause stroke
I usually don’t dwell too much on chiropractic, because so many other bloggers mock them so well. Chiropractors are generally antivaccination, they practice junk medicine in areas in which they are not trained, and they are essentially quacks utilizing some mystical alternative medicine, taking money from people who think they’re getting real medical treatment. Basically, chiropractic is […]Continue reading «Chiropractic manipulation of neck may cause […]
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1:32 PM | What’s The Answer? (SNPs in promoters)
Biostars is a site for asking, answering and discussing bioinformatics questions and issues. We are members of the community and find it very useful. Often questions and answers arise at Biostars that are germane to our readers (end users of genomics resources). Every Thursday we will be highlighting one of those items or discussions here […]
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12:05 PM | Determining value to withstand all tests
The late arrival of an early role for communications
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10:38 AM | Sanofi asks Emcure to sell its cancer drugs in India
Will hand over marketing of Taxotere, Jevtana, Fludara and Fasturtec
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10:24 AM | India has big plans for healthcare and pharma
And the European industry is keen to engage with the new Modi government
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10:12 AM | US talks tough on 'unpatriotic' tax inversion deals
Treasury looks to 'meaningfully reduce' tax benefits of such manoeuvres
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9:48 AM | AbbVie begins 'first-of-its-kind' hep C charity pilot
Will work with Addaction Cornwall and The Hepatitis C Trust
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8:50 AM | FDA approves antibacterial skin drug Orbactiv
US regulator authorises Medicines Company's treatment for ABSSSI
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8:12 AM | Janssen launches online mental health video series
Healthy Minds will focus on brain disorder research and treatment

August 06, 2014

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11:15 PM | Celgene's Abraxane authorised by Health Canada
Drug can now be used as first-line treatment for metastatic pancreatic cancer
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7:47 PM | Fluorescent Cell Imaging Simplified
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7:06 PM | ALS Target: Microglia
Glia, perhaps the most underappreciated of cell types, are finally getting some attention. A new report in Science Translational Medicine from Kevin Eggan’s group at the Harvard Stem Cell Institute validates the role of microglia in amyotrophic lateral sclerosis – aka ALS, motor neuron disease or Lou Gehrig’s disease — and investigates how to manipulate them to extend life, in a mouse model for now.… Read the restThe post ALS Target: Microglia appeared […]
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1:36 PM | Video Tip of the Week: Biodalliance browser with HiSeq X-Ten data
Drama surrounding the $1000 genome erupts every so often, and earlier this year when the HiSeq X Ten setup was unveiled there was a lot of chatter–and questions: Is the $1,000 genome for real? And some push-back on the cost analysis: That “$1000 genome” is going to cost you $72M. A piece that offers nice […]

Down T.A. & T. J. P. Hubbard (2011). Dalliance: interactive genome viewing on the web, Bioinformatics, 27 (6) 889-890. DOI: http://dx.doi.org/10.1093/bioinformatics/btr020

Check Hayden E. (2014). Is the $1,000 genome for real?, Nature, DOI: http://dx.doi.org/10.1038/nature.2014.14530

Dunham I., Shelley F. Aldred, Patrick J. Collins, Carrie A. Davis, Francis Doyle, Charles B. Epstein, Seth Frietze, Jennifer Harrow, Rajinder Kaul & Jainab Khatun & (2012). An integrated encyclopedia of DNA elements in the human genome, Nature, 489 (7414) 57-74. DOI: http://dx.doi.org/10.1038/nature11247

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