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Posts

April 01, 2014

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7:37 PM | How to Design a Foolproof Quantitative Western Blot
A methods article published yesterday provides a rigorous and concise workflow with specific instructions on how to produce and analyze quantitative data using western blot experiments. The paper, coauthored by Bio-Rad scientists and published in BioMed Research International, also highlights recently introduced technologies that improve reproducibility. The result is a powerful, step-by-step guide to obtaining [...]
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2:25 PM | Lemur Week is here, join our tour.
Their ghostly eyes are lovely windows to their souls. Lemurs are primates – they have long tails, tree-climbing hands, and incredible curiosity. At least that’s what I encountered on my visit to the Duke Lemur Center (sponsored by Owen Software). … Continue reading →
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12:55 PM | The Impact of Immunotherapy Trials on the Pharmaceutical Industry
Cancer treatments have often revolved around chemotherapy, surgery, and radiation regimens. However, in recent years, immunotherapy has been revolutionizing the oncology field. There are several important areas of research for immunotherapies including; cancer vaccines, monoclonal antibodies for differentiating cancer cells, and lymphokine-activated killer cell therapy. Cancer immunotherapy studies have really made headway within the healthcare ... continue reading
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12:00 PM | Building a Genome: The First Synthetic Yeast Chromosome
When you were a kid, did you ever dream up fantastical creatures, like cats with wings or super-intelligent dogs that could speak? While we’re nowhere near making such animals, we’re definitely becoming increasingly better at genetically modifying the organisms around us. One amazing recent breakthrough is the creation of a synthetic yeast chromosome. This is … Continue reading »
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9:52 AM | Doctors criticise FDA over Lemtrada rejection
Say Sanofi/Genzyme’s MS drug should have been approved
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9:37 AM | EU approval for Takeda’s schizophrenia drug
Latuda said to have improved side effect profile compared to other treatments
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9:13 AM | Astellas sets up regenerative medicine unit
Will spearhead company's efforts in cell-based therapies
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8:47 AM | Undifferentiated Cells Definition, Sources and Purpose
Undifferentiated cells refers to a cell that has yet to develop into a particular cell variant. Undifferentiated stem cells are the very basic cells in biology that all other cells derive from. The very first few cells in an embryo are considered undifferentiated. Stem cells are basically undifferentiated cells that have the unique ability to […] The post Undifferentiated Cells Definition, Sources and Purpose appeared first on Regeneration Center of Thailand.
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6:49 AM | MiSeq X: is this Illumina's HiSeq 2500 replacement
Illumina are probably going to announce their latest sequencer today and Core Genomics was heard about it before anyone else...MiSeq X. Similar in name to the HiSeq X Ten the MiSeq X borrows many of the improvements seen in it's big brother including new optics, improved chemistry and a stand-alone server for data analysis allowing upload to BaseSpace. There are fewer restrictions about what we can do on MiSeq X, and the "only Human" has gone.You can buy a single MiSeq X unlike the minimum […]

March 31, 2014

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11:58 PM | NEW LINK FOUND BETWEEN BREAST CANCER AND EPIGENETICS
Breast cancer is one of the most common cancers worldwide in females. Researchers from the University of California, Los Angeles (UCLA) found that PIAS1 is linked to breast tumorigenesis. PIAS1 is a transcriptional repressor that has SUMO (small ubiquitin-like modifier) E3 ligase activity. Recently, it had been explored that PIAS1 facilitates a novel epigenetic mechanism ...The post NEW LINK FOUND BETWEEN BREAST CANCER AND EPIGENETICS appeared first on EpiBeat.
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11:30 PM | GSK halts bid for Votrient maintenance use
Pulls European application for indication in advanced ovarian cancer
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11:16 PM | Sanofi appoints ‘chief patient officer’
Dr Anne Beal will lead pharma company’s efforts to improve its focus on patients
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11:15 PM | Print health ad spend in US remains buoyant
Companies paid $45m on advertising in professional print journals in January 2014, a 7 per cent rise year-on-year
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11:15 PM | Associate director hire marks Portland Health’s birthday
London health comms agency celebrates its first anniversary by adding Matt Worrall
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11:02 PM | Interview: Georg Toufar, Mundipharma
Mundipharma’s chief marketing officer Georg Toufar on the benefits of having a smaller, more concentrated focus
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7:01 PM | 2-D Electrophoresis Tips & Tricks – Part II
Tweet This Post
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4:53 PM | No time for coats: Jupiter is outside
I only noticed the cold after my fingers had stopped responding. I wasn’t able to press the camera shutter button any longer. In that 20 degrees F night, I was standing in the sidewalk with Science Online friends, and I … Continue reading →
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2:37 PM | Asp-N Protease: Applications Update
Asp-N, Sequencing Grade, is an endoproteinase that hydrolyzes peptide bonds on the N-terminal side of aspartic and cysteic acid residues: Asp and Cys. Asp-N activity is optimal in the pH range of 4.0–9.0. This sequencing grade enzyme can be used alone or in combination with trypsin or other proteases to produce protein digests for peptide […]
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1:17 PM | Aptiv Solutions to be Acquired by ICON
Combined companies provide unrivalled capabilities for adaptive and medical device trials worldwide Reston, Virginia, 31st March, 2014 – Aptiv Solutions, a global biopharmaceutical and medical device development services company leading the design and implementation of innovative approaches that improve data quality, efficiency, and productivity of product development today announced that it has agreed, subject to ... continue reading
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11:03 AM | Novartis' dual-action heart failure drug aces trial
Ends LCZ696 trial early on good results
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11:02 AM | Certainty comes too late
In the first of a new regular column, Professor Brian D Smith points out the practical implications of an evolving pharma market
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10:49 AM | GSK invests in African research and manufacturing
Boosts R&D for non-communicable diseases
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10:43 AM | Final NICE ‘no’ for J&J’s Stelara in psoriatic arthritis
Committee says drug is more expensive and less effective than TNF alpha inhibitors
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9:17 AM | AZ teams up with UK's MRC for discovery centre
Public-private facility will be based at the pharma company's Cambridge R&D site
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2:07 AM | Thoughts About Norm Borlaug for his 100th Birthday
Norman Borlaug would have been 100 years old last week.  He has been called “The Man Who Fed The World,” and “The Father of The Green Revolution.”  Norm Borlaug was the first plant pathologist to be awarded a Nobel Prize (1970) – for contributions to world peace. For all of use who are fellow plant pathologists, his work has been particularly inspiring. It is a good time to look back at how the challenge of feeding the world population was met during […]

March 30, 2014

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11:30 PM | Individualized Medicine from Prewomb to Tomb: Cell
Individualized Medicine from Prewomb to Tomb: Cell
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11:15 PM | Merck & Co appoints new financial head
Baxter’s Robert Davis takes over from Peter Kellogg
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2:25 AM | "Drugs are Expensive" Biotech Reading List
The $1000 per day price tag of Gilead's new Hepatitis C therapy SOVALDI has triggered the latest round of chatter about high drug prices in the US market. A round-up of reaction and some related articles are below.Breaking The Bank: Sovaldi And The Cost [...]
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2:06 AM | Journal Watch
New FDA Breakthrough-Drug Category — Implications for Patients [free full text]Jonathan J. Darrow, Jerry Avorn, M.D., and Aaron S. KesselheimNew England Journal of Medicine2014; 370:1252-1258March 27, 2014DOI: 10.1056/NEJMhle1311493 [...]

March 28, 2014

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5:43 PM | Bovine TB controversy: Do deer farms spread the disease to cattle farms?
Controversy rages over whether Chronic Wasting Disease (CDW) in deer and elk, specifically found in high occurrences on deer farms, is spreading to cattle farms. In cattle, the equivalent disease is known as “Mad Cow Disease.” Deer farmers are busy compiling and presenting evidence that their farms present no threat to wildlife or other livestock farms. They claim CDW is a “political disease” wherein government agencies are wielding an agenda and fear rather than working […]
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