Posts

October 06, 2014

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9:35 PM | Another flu vaccine myth–Big Pharma profits
The 2014-15 flu season is upon us, and that means it’s flu vaccine time again. Despite the availability of several flu vaccines, many people think that the flu is a painless, harmless disease, a belief belied by evidence. To put flu in perspective, in the USA, depending on the severity of the flu season, from 3,000 (which happened 25 years […]Continue reading «Another flu vaccine myth–Big Pharma profits»
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7:16 PM | The Sophisticated European Scientist
Another example of how European scientists are more sophisticated than their American counterparts. Tweet This Post
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3:18 PM | Bioinformatics tools extracted from a typical mammalian genome project [supplement]
This is Table 1 that accompanies the full blog post: Bioinformatics tools extracted from a typical mammalian genome project. See the main post for the details and explanation. The table is too long to keep in the post, but I wanted it to be web-searchable. A copy also resides at FigShare: http://dx.doi.org/10.6084/m9.figshare.1194867 Software tool/object/item/resource access […]

Carbone L., R. Alan Harris, Sante Gnerre, Krishna R. Veeramah, Belen Lorente-Galdos, John Huddleston, Thomas J. Meyer, Javier Herrero, Christian Roos, Bronwen Aken & Fabio Anaclerio (2014). Gibbon genome and the fast karyotype evolution of small apes, Nature, 513 (7517) 195-201. DOI: http://dx.doi.org/10.1038/nature13679

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3:12 PM | Bioinformatics tools extracted from a typical mammalian genome project
In this extended blog post, I describe my efforts to extract the information about bioinformatics-related items from a recent genome sequencing paper, and the larger issues this raises in the field. It’s long, and it’s something of a hybrid between a blog post and a paper format, just to give it some structure for my […]

Carbone L., R. Alan Harris, Sante Gnerre, Krishna R. Veeramah, Belen Lorente-Galdos, John Huddleston, Thomas J. Meyer, Javier Herrero, Christian Roos, Bronwen Aken & Fabio Anaclerio (2014). Gibbon genome and the fast karyotype evolution of small apes, Nature, 513 (7517) 195-201. DOI: http://dx.doi.org/10.1038/nature13679

Citation
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3:04 PM | Tasi e Tari 2014: ecco come si calcolano
La scadenza per il pagamento è tra pochi giorni: il 16 ottobre. Arriva la Tasi, la temibile imposta che colpirà presto non solo i proprietari di case, ma anche gli inquilini. Molti si interrogano ancora sui meccanismi alla base delle nuove…Read more →
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2:20 PM | Sugar rush: The development of glucose-sensitive beta cells from embryonic precursors
> “Wow, my mouth just got diabetes.” Such are my immediate thoughts after taking a bite out of a red velvet cupcake.  Though I must qualify: by cupcake, I mean a skyscraper of frosting carefully balanced on a minimal crumbly foundation. Making such a hyperbolic statement heightens our awareness that diabetes involves intolerably high blood...Read more
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2:11 PM | Free Webinar: Protein Reference Materials for Mass Spectrometry
Once the domain of analytical chemistry labs, mass spectrometry instruments are now used in basic life science research, drug discovery research, environmental and industrial laboratories, and in many other biological laboratories. These instruments, which are used to perform critical analyses, need to be monitored for performance and quality. How do you determine the system suitability […]
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11:20 AM | Facebook 'considering' new online health communities and apps
Social network is reportedly exploring healthcare options
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10:33 AM | Takeda loses in lawsuit claiming cancer link to Actos
Ordered to compensate woman who claims drug gave her bladder cancer
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9:59 AM | Trials of NewLink's Ebola vaccine 'imminent'
NewLink and GSK candidates only two vaccines being tested
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9:31 AM | Roche appoints Philip Atkinson to new global role
He will lead the company's new scientific communications group
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9:21 AM | Breast cancer drug market set to double in 10 years
New entrants will join market leaders Roche, Novartis and AstraZeneca
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1:39 AM | Biotech Tweets of the Week (Sept 29 - Oct 3)
Enjoy the latest round-up of the top tweets of the week that drove and captured the conversation this week. Thanks as always to @23aloha for the heavy lifting on the curation. Featured tickers: $AKBA $ANTH $BMY $NWBO $RHHBY $RTRX $SLXP $TKMR $TNXP Even with the placebo group crossing over to pertuzumab, the OS w/ combo is still fantastic #CLEOPATRA #esmo14 pic.twitter.com/rCoPwyf82B— Sally Church (@MaverickNY) September 28, 2014 @Jerry_DurhamPT absolutely, health first, […]

October 05, 2014

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11:30 PM | Triducive appoints Ian Walker as senior account manager
He joins the communications consultancy from the RSA Group

October 04, 2014

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1:28 PM | Studi geologici nell’area archeologica marina di Sinuessa per la valorizzazione del sito
In Campania, nell’area archeologica marina sommersa di Sinuessa, città romana risalente al III secolo a.C,  da circa due anni il Laboratorio di Chimica Ambientale del Centro di Ricerca ENEA di Portici svolge studi geologici e rilievi geomorfologici sui reperti dell’antico…Read more →

October 03, 2014

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9:12 PM | Poll: what’s scarier than Ebola
There are actually more worrisome public health issues than Ebola. What worries you?Continue reading «Poll: what's scarier than Ebola»
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8:41 PM | Lions, tigers and ebola–oh my!
Unless you’ve been living under a rock (which is admittedly difficult), you might be aware of the Ebola virus. And that it has entered the USA–one patient, not exactly an epidemic. And, according to public health officials, about 10 people are at risk from the disease from contact with this “patient zero” in the USA. […]Continue reading «Lions, tigers and ebola–oh my!»
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3:01 PM | Detecting Inhibition of Protein Interactions in vivo
In a paper published in the September issue of ACS Medicinal Chemistry Letters, researchers from GlaxoSmithKline in the UK and Germany report on the discovery, binding mode and structure:activity relationship of a new, potent BRPF1 (bromodomain and PHD finger containing protein family) inhibitor. This paper came to our attention as it is one of the […]
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1:16 PM | Biotechnology and the Risky Art of Being Unnatural
Everything we do carries risk. The clothes we wear are synthetic. The food we eat is unnatural. Yet, we thrive. Genetic engineering, first attempted in the late 20th century, is a process of altering specific genetic material to change heredity traits of a cell or organism.  The resulting organism is deemed genetically modified (GM).
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1:13 PM | Friday SNPpets
Welcome to our Friday feature link collection: SNPpets. During the week we come across a lot of links and reads that we think are interesting, but don’t make it to a blog post. Here they are for your enjoyment… RT @bbuliksullivan: Writing an intro paragraph. I refuse to use the phrase “missing heritability” and you […]
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1:00 PM | Right Turn: There’s beauty in science
. The colourful, beautiful, whimsical, original, intriguing (I could go on) images that were submitted to CCRM for its Cells I See contest are live on Facebook for your viewing pleasure and votes. Until October 18, 2014 people are encouraged to “like” their favourite image. The one with the most likes will be this year’s...Read more
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10:58 AM | EMA draws fire on new clinical reports policy
Has recently come under pressure from transparency groups
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10:43 AM | Medical device firms told to address cybersecurity risks
FDA says online security should be part of a device's design and development
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9:35 AM | Lilly drops tabalumab after lupus joins arthritis on failure list
Firm said it would take a $75m charge in the fourth quarter
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2:42 AM | The day I unwittingly became a pro-science activist
Early this September I attended the National Heirloom Expo in Santa Rosa.  It’s an event that’s centered around the pure food movement, heirloom vegetables, and anti-GMO activism.  The speakers included Joseph Mercola, Jeffrey Smith, Andrew Kimbrell, and my personal favorite pseudoscientist, Vani Hari, a.k.a. the Food Babe.  For those unfamiliar with Food Babe, she is an anti-GMO, pro-organic public figure who attacks food and agricultural companies for what are […]

October 02, 2014

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11:31 PM | NICE denies Roche cancer drug due to ‘data uncertainties’
Unable to recommend Gazyvaro for untreated chronic lymphocytic leukaemia
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11:30 PM | INC Research appoints Claire Grace
She joins from PPD as VP site and patient access
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11:30 PM | Young diabetes patients in England and Wales receive fewer vital checks
Less than a third with type 1 diabetes receive eight of nine recommended care processes
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11:15 PM | Astellas names president of US technologies business
Promotion for Brian McLellan
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7:58 PM | Dog’s Epigenome Gives Clues to Human Cancer
The bond between humans and dogs is strong and ancient. From being the protector of the first herds in a faithful pet, dogs and people share many aspects of life. The relationship between the two species has been studied by psychologists, anthropologists, ethnologists and also by genetic and molecular biologists. In this sense, dogs are […]
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