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December 12, 2012

1:30 PM | Advancing the Promise of Personalized Medicine: Companion Diagnostics

When I was a sophomore in college, my mother unfortunately lost her very short battle with pancreatic cancer, an experience that changed my life forever. During that time I witnessed firsthand the devastating effects caused by the administration of toxic, non-specific treatments which ultimately failed to stop the spread of the cancer, and instead only [...]

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Computer science on prediction and the edge of chaos

With the development of statistical mechanics, physicists became the first agent-based modellers. Since the scientists of the 19th century didn’t have super-computers, they couldn’t succumb to the curse of computing and had to come up with analytic treatments of their “agent-based models”. These analytic treatments were often not rigorous, and only a heuristic correspondence was […]

Chazelle, B. (2012). Natural algorithms and influence systems, Communications of the ACM, 55 (12) 101. DOI: 10.1145/2380656.2380679

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What music do dogs prefer? Bach vs. Snoop Dogg

Hey Julie,I hope you've had a fun week. I saw a new in-press publication with your name on it - "Smelling more or less: Investigating the olfactory experience of the domestic dog" - looks like a really great study, and so timely after my last post about dogs and olfactory enrichment! Looking forward to reading it (and all those other cool Learning and Motivation articles) over the weekend. So did you do your homework? Did you watch this clip from the Sydney Opera […]

Kogan L.R., Schoenfeld-Tacher R. & Simon A.A. (2012). Behavioral effects of auditory stimulation on kenneled dogs, Journal of Veterinary Behavior: Clinical Applications and Research, 7 (5) 268-275. DOI: 10.1016/j.jveb.2011.11.002

Wells D., Graham L. & Hepper P. (2002). The influence of auditory stimulation on the behaviour of dogs housed in a rescue shelter., Animal Welfare, 11 (4) 385-393. Other: Link

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Did you like this photo? No, really like…

Researchers in Germany and the US have developed an algorithm that can work out whether comments on a photo or video (and eventually any shared digital document) are being positive or negative about the quality of the photo, or critical about the subject of the photo itself. So a blurry, underexposed snap of Justin Bieber [...]Related Posts:Media, marketing, mutualitySaving power on the cloudDoubling broadband brings 0.3% economic “boost”Wikimaps plots important points on Wikipedia8 […]

Kisilevich S., Rohrdantz C., Maidel V. & Keim D. (2013). What do you think about this photo? A novel approach to opinion and sentiment analysis of photo comments, International Journal of Data Mining, Modelling and Management, 5 (2) 138. DOI: 10.1504/IJDMMM.2013.053693

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A State of Dis”array”: Two Recent Studies Highlight Common Problems Associated with Using Illumina’s 450k Array for Epigenetics Research

Epigenetic analysis is one of the hottest areas in all of biological research. Covalent modifications to DNA, proteins, and RNA, without changing the primary sequence of these molecules, are known to epigenetically regulate numerous cellular processes and contribute to many important human disease phenotypes. One of the most intensely studied epigenetic modifications is DNA methylation ...

Chen YA, Lemire M, Choufani S, Butcher DT, Grafodatskaya D, Zanke BW, Gallinger S, Hudson TJ & Weksberg R (2013). Discovery of cross-reactive probes and polymorphic CpGs in the Illumina Infinium HumanMethylation450 microarray., Epigenetics : official journal of the DNA Methylation Society, 8 (2) 203-9. PMID: 23314698

Harper KN, Peters B & Gamble MV (2013). Batch Effects and Pathway Analysis: Two Potential Perils in Cancer Studies Involving DNA Methylation Array Analysis., Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, PMID: 23629520

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Why do they love us so?

Jeroen Spitzen quickly snaps on a glove. He takes a deep breath, as he rolls up his sleeve to expose his arm. Before him is a cage that is literally, … Continue reading →

Spitzen J., Spoor C.W., Grieco F., ter Braak C., Beeuwkes J., van Brugge S.P., Kranenbarg S., Noldus L.P.J.J., van Leeuwen J.L. & Takken W. & (2013). A 3D Analysis of Flight Behavior of Anopheles gambiae sensu stricto Malaria Mosquitoes in Response to Human Odor and Heat, PLoS ONE, 8 (5) e62995. DOI: 10.1371/journal.pone.0062995.s009

Verhulst N.O., Qiu Y.T., Beijleveld H., Maliepaard C., Knights D., Schulz S., Berg-Lyons D., Lauber C.L., Verduijn W. & Haasnoot G.W. & (2011). Composition of Human Skin Microbiota Affects Attractiveness to Malaria Mosquitoes, PLoS ONE, 6 (12) e28991. DOI: 10.1371/journal.pone.0028991.s004

Verhulst N.O., Mbadi P.A., Kiss G., Mukabana W.R., van Loon J.J., Takken W. & Smallegange R.C. (2011). Improvement of a synthetic lure for Anopheles gambiae using compounds produced by human skin microbiota, Malaria Journal, 10 (1) 28. DOI: 10.1186/1475-2875-10-28

Smallegange R.C., van Gemert G.J., van de Vegte-Bolmer M., Gezan S., Takken W., Sauerwein R.W., Logan J.G. & Dimopoulos G. (2013). Malaria Infected Mosquitoes Express Enhanced Attraction to Human Odor, PLoS ONE, 8 (5) e63602. DOI: 10.1371/journal.pone.0063602.g001

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December 12, 2012

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