According to a new paper, one of neuroscience's most famous case-studies came about as a result of a serious medical blunder.
Henry Molaison (1926 - 2008), better known as HM, was an American man who developed a dramatic form of amnesia after receiving surgery that removed part of the temporal lobes of his brain. The 1953 operation was intended to treat HM's epilepsy, but it had the side effect of leaving him unable to form new memories.
The consequences of HM's surgery are well known
Antibodies defend the body against bacterial, viral, and other invaders. But sometimes the body makes antibodies that attack healthy cells. In these cases, autoimmune disorders develop. Immune abnormalities in patients with psychosis have been recognized for over a century, but it has been only relatively recently that scientists have identified specific immune mechanisms that seem to […]
There are at least two ways of how the topic of trust in God is broached in Friday sermons that I have attended in the United States. Some imams lament the decrease of trust in God in the age of modernity. Instead of trusting God that He is looking out for the believers, modern day Muslims believe that they can control their destiny on their own without any Divine assistance. These imams see this lack of trust in God as a sign of weakening faith and an overall demise in piety. But in recent […]
The paper from José Guevara-Campos and colleagues  (open-access can be downloaded here) is fodder for today's short post, and a topic that has not been seen on this blog for quite a while: hyperlactacidemia (elevated plasma lactate levels) and autism.Previous mentions of lactate and autism on this blog (see here and see here) were potentially pretty important; specifically, how elevated plasma lactate levels might (a) not be an unfamiliar finding for quite a few people on
Guevara-Campos J, González-Guevara L & Cauli O (2015). Autism and Intellectual Disability Associated with Mitochondrial Disease and Hyperlactacidemia., International journal of molecular sciences, 16 (2) 3870-3884. PMID: http://www.ncbi.nlm.nih.gov/pubmed/25679448
It might have been an accident, but like some lucky researchers accidents are a good thing. In this particular case, scientists have discovered a new way to manipulate how cells function, a finding that might help advance an experimental approach to improving public health: DNA vaccines, which could be more efficient, less expensive and easier […]
Gou, Y., Byun, H., Zook, A., B. Singh, G., Nash, A., Lozano, M. & Dudley, J. (2015). Retroviral vectors elevate coexpressed protein levels in trans through cap dependent translation
through cap-dependent translation
, Proceedings of the National Academy of Sciences, 201420477. DOI: 10.1073/pnas.1420477112