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April 01, 2013

12:25 PM | Interview with a Saber Tooth Tiger

From our science correspondent AA. AA: We’re in a cave at an undisclosed location on the Himalayas, interviewing Ms. Lilypad, a saber tooth tiger. Ms. Lilypad, what made you agree to this interview after your species has lived incognito for literally millennia? LP: I got tired listening to the TED goombahs going on and on about de-extinction. [...]

Scientific American - Guest Blog

General Science

February 24, 2013

5:17 PM | The “Language” Gene and Women’s Wagging Tongues

Aka, How to Twist Science to Reinforce Gender Stereotypes Genes are subject to multiple layers of regulation. An early regulatory point is transcription. During this process, regulatory proteins bind to DNA regions (promoters and enhancers) that direct gene expression. These DNA/protein complexes attract the transcription apparatus, which docks next to the complex and proceeds linearly [...]

Scientific American - Guest Blog

General Science

September 17, 2012

8:33 PM | Junk DNA, Junky PR

A week ago, a huge, painstakingly orchestrated PR campaign was timed to coincide with multiple publications of a long-term study by the ENCODE consortium in top-ranking journals. The ENCODE project (EP) is essentially the next stage after the Human Genome Project (HGP). The HGP sequenced all our DNA (actually a mixture of individual genomes); the [...]

Scientific American - Guest Blog

General Science

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Autism, plasma cytokines and siblings

I'm gonna try and be fairly brief in this post on the paper by Valerio Napolioni and colleagues* (open-access) looking at plasma cytokine profiles in cases of autism and their asymptomatic siblings. Brief because (a) the paper is open-access and (b) the participant groups (autism: n=25; sibling controls n=25) were relatively small so one has to be quite careful in extrapolating the findings with any large degree of confidence.Siblings by Paul Klee @ WikiPaintings Just in case you are […]

Napolioni V, Ober-Reynolds B, Szelinger S, Corneveaux JJ, Pawlowski T, Ober-Reynolds S, Kirwan J, Persico AM, Melmed RD, Craig DW & Smith CJ (2013). Plasma cytokine profiling in sibling pairs discordant for autism spectrum disorder., Journal of neuroinflammation, 10 38. PMID: 23497090

Questioning Answers

Psychiatry | Psychology

Citation

Blood magic: old blood ages the young

“Our ancient countess was refused her desires will To bathe in pure fresh blood She’d peasant virgins killed Elizabeth, in the chasm where was my soul Forever young, Elizabeth Bathorii in the castle of your death You’re still alive, Elizabeth” -“Elizabeth”, Ghost As folklore has it, Elizabeth Bathorii, Countess of Hungary, often […]

Villeda SA, Luo J, Mosher KI, Zou B, Britschgi M, Bieri G, Stan TM, Fainberg N, Ding Z, Eggel A & Lucin KM (2011). The ageing systemic milieu negatively regulates neurogenesis and cognitive function., Nature, 477 (7362) 90-4. PMID: 21886162

Loffredo FS, Steinhauser ML, Jay SM, Gannon J, Pancoast JR, Yalamanchi P, Sinha M, Dall'osso C, Khong D, Shadrach JL & Miller CM (2013). Growth Differentiation Factor 11 Is a Circulating Factor that Reverses Age-Related Cardiac Hypertrophy., Cell, 153 (4) 828-39. PMID: 23663781

Zhang G, Li J, Purkayastha S, Tang Y, Zhang H, Yin Y, Li B, Liu G & Cai D (2013). Hypothalamic programming of systemic ageing involving IKK-β, NF-κB and GnRH., Nature, 497 (7448) 211-6. PMID: 23636330

Neurorexia

Medicine | Neuroscience

Citation

Natural algorithms and the sciences

Today, I am passing through New York City on my way to Princeton’s Center for Computational Intractability for a workshop on Natural Algorithms and the Sciences (NA&S). The two day meeting will cover everything from molecular algorithms for learning and experiments on artificial cells to bounded rationality in decision-making and the effects of network topology […]

Chazelle, B. (2012). Natural algorithms and influence systems, Communications of the ACM, 55 (12) 101. DOI: 10.1145/2380656.2380679

Theory, Evolution, and Games Group

Biology | Mathematics

Citation

Reflecting on Applied Animal Behavior

Time for reflection (By Wieselblitz)Hi Mia! Love the lavender research! Learning that dogs show different behaviors when exposed to different scents could help us prime environments to be associated with particular dog behaviors and moods (you noted that exposure to peppermint and rosemary are associated with activity and barking while exposure to lavender and chamomile bring out resting). At the Horowitz Dog Cognition Lab, we have a new paper coming out soon in Learning and Motivation -- the […]

Mason G., Clubb R., Latham N. & Vickery S. (2007). Why and how should we use environmental enrichment to tackle stereotypic behaviour?, Applied Animal Behaviour Science, 102 (3-4) 163-188. DOI: 10.1016/j.applanim.2006.05.041

Do you believe in dog?

Academic Life | Behavioral Biology

Citation

A deeper look at the geology of diamonds

The geology of diamonds is fascinating in itself, but they also give insights into wider geological processes and history. Up until 1725, diamonds were only known from India. That all changed when Brazilians panning river sediments for gold, instead found diamonds. Recent … Continue reading →

Harte, B. & Richardson, S. (2012). Mineral inclusions in diamonds track the evolution of a Mesozoic subducted slab beneath West Gondwanaland, Gondwana Research, 21 (1) 236-245. DOI: 10.1016/j.gr.2011.07.001

Harte, B. & Cayzer, N. (2007). Decompression and unmixing of crystals included in diamonds from the mantle transition zone, Physics and Chemistry of Minerals, 34 (9) 647-656. DOI: 10.1007/s00269-007-0178-2

Metageologist

Geosciences

Citation