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February 07, 2013

“Why don’t you spend more on my cancer type?” and “why don’t you do more to highlight awareness?” These are two questions we hear frequently, and topics that are close to many of our supporters’ hearts. Understandably, everyone who has … Continue reading →

October 25, 2012

4:14 PM | Imatinib – the dawn of targeted treatments

Thirty years ago, we published research that was a key early step in the journey towards the first genetically tailored cancer drug, imatinib (also known as Glivec, or Gleevec in the United States). This drug changed the landscape, not just for … Continue reading →

August 28, 2012

9:26 AM | Twenty-five years since landmark bowel cancer discovery

There’s a lot more to do before we can say we’ve beaten cancer, but every now and then, it’s good to sit back and reflect on how far we’ve already come. Back in June, when the country was celebrating the … Continue reading →

June 20, 2012

4:24 PM | Cancer intelligence: mission possible

Imagine a future where you can go online and compare which hospital is the best in your area to treat your type of cancer. A future where, as a cancer patient, you have all the information you need to be … Continue reading →

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Offshore Drilling Helps Microbiologists Study Life on Earth and Beyond

Offshore drilling is often discussed in terms of its positive effect on the economy and the potential risks it carries for the environment. There’s, however, another side to offshore drilling, one that is less often talked about. A recent study done at the University of Aberdeen, suggests that the oil and gas industry’s pursuit of new oil reserves has contributed to a greater understanding of where life exists on Earth and may even help us look for life on other planets. Read more »

Parnell, J., Boyce, A., Hurst, A., Davidheiser-Kroll, B. & Ponicka, J. (2013). Long term geological record of a global deep subsurface microbial habitat in sand injection complexes, Scientific Reports, 3 DOI: 10.1038/srep01828

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Marijuana and Diabetes: Does Pot Make You Thin?

Teasing out the insulin effect. On the face of it, the study seems to come out of left field: A group of researchers claimed that marijuana smokers showed 16 per cent lower fasting insulin levels than non-smokers. The study, called “The Impact of Marijuana Use on Glucose, Insulin, and Insulin Resistance among US Adults,” is in press for The American Journal of Medicine. The authors are a diverse group of medical researchers from Harvard, Beth Israel Deaconess Medical Center, and […]

Penner E.A., Buettner H. & Mittleman M.A. (2013). The Impact of Marijuana Use on Glucose, Insulin, and Insulin Resistance among US Adults, The American Journal of Medicine, DOI: 10.1016/j.amjmed.2013.03.002

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3D patterning of blood vessels: Creating a fertile landscape for engineered tissues

Nepalese terraces. Photo: strudelt via Flickr . Picture traveling back in time to an era before cell phones (*shudder*). Before radios. Before germ theory. In fact, try taking yourself back to when written language was first being developed around 6000 BC. It’s hard to imagine. And yet while these societies may have lacked our freeways...Read more

Baranski J.D., Chaturvedi R.R., Stevens K.R., Eyckmans J., Carvalho B., Solorzano R.D., Yang M.T., Miller J.S., Bhatia S.N. & Chen C.S. & (2013). Geometric control of vascular networks to enhance engineered tissue integration and function., Proceedings of the National Academy of Sciences of the United States of America, PMID: 23610423

Vunjak-Novakovic G., Tandon N., Godier A., Maidhof R., Marsano A., Martens T.P. & Radisic M. Challenges in cardiac tissue engineering., Tissue engineering. Part B, Reviews, PMID: 19698068

Marolt D., Knezevic M. & Novakovic G.V. (2010). Bone tissue engineering with human stem cells., Stem cell research & therapy, PMID: 20637059

Metcalfe A.D. & Ferguson M.W.J. (2007). Tissue engineering of replacement skin: the crossroads of biomaterials, wound healing, embryonic development, stem cells and regeneration, Journal of The Royal Society Interface, 4 (14) 413-437. DOI: 10.1098/rsif.2006.0179

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Video Tip of the Week: Canary Database for sentinels of human health

Recently we attended the Medical Library Association conference (#MLAnet13). Librarians are working so hard to wrangle information into usable forms, and to generate new connections among data types to reveal new information and leads for further studies. I ♥ librarians. In one of the sessions I attended on Medical Informatics, I heard several great talks. One [...]

Rabinowitz, P., Scotch, M. & Conti, L. (2010). Animals as Sentinels: Using Comparative Medicine To Move Beyond the Laboratory, ILAR Journal, 51 (3) 262-267. DOI: 10.1093/ilar.51.3.262

Rabinowitz, P., Gordon, Z., Holmes, R., Taylor, B., Wilcox, M., Chudnov, D., Nadkarni, P. & Dein, F. (2005). Animals as Sentinels of Human Environmental Health Hazards: An Evidence-Based Analysis, EcoHealth, 2 (1) 26-37. DOI: 10.1007/s10393-004-0151-1

Rabinowitz, P., Cullen, M. & Lake, H. (1999). Wildlife as sentinels for human health hazards: a review of study designs, Journal of Environmental Medicine, 1 (4) 217-223. DOI: 10.1002/jem.33

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Dogs can haz brainscanz and EEG?

Canine cognition is a hot topic these days, using experiments and brain imaging as research tools. The trouble with brain imaging work is that it is invasive, to the extent that animals may have to be sedated or anaesthetized for the study. All that changed with the amazing work of Gregory Berns et al and the first-ever fMRI study on awake, unrestrained dogs last year. Now Miiamaaria Kujala et al in Finland have shown that it is also possible to do a non-invasive EEG with dogs.An EEG […]

Berns, G., Brooks, A. & Spivak, M. (2012). Functional MRI in Awake Unrestrained Dogs, PLoS ONE, 7 (5) DOI: 10.1371/journal.pone.0038027

Kujala, M., Törnqvist, H., Somppi, S., Hänninen, L., Krause, C., Vainio, O. & Kujala, J. (2013). Reactivity of Dogs' Brain Oscillations to Visual Stimuli Measured with Non-Invasive Electroencephalography, PLoS ONE, 8 (5) DOI: 10.1371/journal.pone.0061818

Ma, H., Qin, L., Dong, C., Zhong, R. & Sato, Y. (2013). Comparison of Neural Responses to Cat Meows and Human Vowels in the Anterior and Posterior Auditory Field of Awake Cats, PLoS ONE, 8 (1) DOI: 10.1371/journal.pone.0052942

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February 07, 2013

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