December 18, 2014

4:20 PM | Histamine and Anorexia Nervosa
Most of us have at some point in our lives taken antihistamines–drugs that block the action of histamine (e.g., Claritin, Allegra)–to relieve allergy symptoms. And while histamine is best known for its role in the immune response, it also has many other important roles in the central nervous system. In the brain, histamine release is important for arousal (this is why antihistamines tend to make us drowsy). It has also been implicated in regulating appetite, taste […]

December 05, 2014

1:27 PM | Treating Severe Anorexia Nervosa in the Community
Can treatment for severe anorexia nervosa be delivered safely in a community setting? According to a recent paper by Calum Munro and colleagues (2014, open access), the answer is yes. In 2001, a systematic review by Meads, Gold, and Burls found that inpatient treatment is not more or less effective than outpatient treatment for individuals with AN. Of course there will always be patients who will require inpatient care, but given the high cost, lack of clear efficacy, and known risks, it is […]
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