Posts

May 31, 2012

+

2:11 PM | Our Stratified Medicine Programme – two years on

In the not-too-distant future, most people treated for cancer (and many other diseases) will have some sort of genetic test performed on their cancer, to help their doctor decide which treatments are likely to work best. In fact, this ‘genetic … Continue reading →

May 22, 2012

+

2:58 PM | Translating breast cancer’s life history

Nestling in the Cambridgeshire countryside, the Wellcome Trust Sanger Institute is a hot-bed of cutting-edge genetic research. The Institute played a key role in deciphering the human genome at the turn of the millennium, and is continuing to make huge strides in … Continue reading →

Stephens, P., Tarpey, P., Davies, H., Van Loo, P., Greenman, C., Wedge, D., Zainal, S., Martin, S., Varela, I., Bignell, G. & Yates, L. (2012). The landscape of cancer genes and mutational processes in breast cancer, Nature, DOI: 10.1038/nature11017

Nik-Zainal, S., Alexandrov, L., Wedge, D., Van Loo, P., Greenman, C., Raine, K., Jones, D., Hinton, J., Marshall, J., Stebbings, L. & Menzies, A. (2012). Mutational Processes Molding the Genomes of 21 Breast Cancers, Cell, DOI: 10.1016/j.cell.2012.04.024

Nik-Zainal, S., Van Loo, P., Wedge, D., Alexandrov, L., Greenman, C., Lau, K., Raine, K., Jones, D., Marshall, J., Ramakrishna, M. & Shlien, A. (2012). The Life History of 21 Breast Cancers, Cell, DOI: 10.1016/j.cell.2012.04.023

Citation

May 16, 2012

+

11:29 AM | Abiraterone: now available on the NHS (except in Scotland)

Regular readers will know that we’ve been keenly following the story of abiraterone – a prostate cancer drug developed by British scientists – since 2008. So we hope you share our delight over this morning’s news, that NICE and pharma … Continue reading →

May 05, 2012

+

8:00 AM | News Digest: low bladder and lung cancer awareness, pancreatic cancer genes, a breast cancer ‘blood test’, and more

Here’s our weekly digest of all the main discoveries and developments this week. We’re still playing around with the format of this digest – let us know what works for you. News from Cancer Research UK It’s been a busy … Continue reading →

May 03, 2012

+

1:21 PM | New breast cancer ‘blood test’ is still work in progress

Earlier this week, the news was full of stories about a ‘blood test’ that can apparently predict a woman’s risk of breast cancer, years before she develops the disease. This sounds exciting. Being able to work out someone’s risk of … Continue reading →

Brennan, K., Garcia-Closas, M., Orr, N., Fletcher, O., Jones, M., Ashworth, A., Swerdlow, A., Thorne, H., , ., Riboli, E. & Vineis, P. (2012). Intragenic ATM Methylation in Peripheral Blood DNA as a Biomarker of Breast Cancer Risk, Cancer Research, 72 (9) 2304-2313. DOI: 10.1158/0008-5472.CAN-11-3157

Citation

April 28, 2012

+

8:00 AM | News digest – tobacco packaging, cutting bowel cancer deaths, aspirin, and more

Here are the week’s top headlines: “New report and film reveal shocking impact of tobacco packaging on children” (press release) Young people and women are target groups for tobacco packaging, according to a report we released this week, alongside a … Continue reading →

April 18, 2012

+

5:00 PM | Increasing the resolution on breast cancer – the METABRIC study

The emotion and anxiety aroused by a single word – ‘cancer’ – spans ages, sexes, nations, races and classes. But as we understand more about the disease, the idea that cancer is a single, common enemy, is increasingly being challenged. … Continue reading →