Posts

November 09, 2012

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Recently, I came across the headline “Scientists Find Achilles’ Heel of Cancer Cells”, describing the discovery of a histone deactylase (HDAC11) as a novel target for cancer therapies. I was irritated by the metaphor of Achilles’ heel, because it implied that this was the lone vulnerability of cancer. I was also embarrassed by the fact [...]

October 09, 2012

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11:05 AM | The Prize in Biology in Memory of Alfred Nobel

The days leading up to the announcements of the Nobel Prizes as well as the aftermath are gossip heaven for us scientists. We love to speculate who will win and after the announcements, we exchange wild conspiracy theories, talk about the painful snubs and pontificate on whether or not the recipients deserve the honors. Our [...]

September 23, 2012

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4:19 PM | Can the Source of Funding for Medical Research Affect the Results?

Many clinical research studies are funded by pharmaceutical companies and there is a general perception that such industry-based funding could potentially skew the results in favor of a new medication or device. The rationale underlying this perception regarding the influence of industry funding is fairly straightforward. Pharmaceutical companies or device manufacturers need to increase the [...]

August 02, 2012

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8:10 PM | Accuracy of Medical Information on the Internet

“We can just Google it!” is becoming our standard response to unanswered questions in life. Whether we are looking for the title of an irritating 80s song, a restaurant serving authentic Icelandic food or the quickest bus route to the Star Trek convention, the Internet usually offers the long-sought answers. However, when we enter key [...]

April 24, 2012

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11:56 AM | Open Science and Access to Medical Research

It is rather odd how often I hear the expression paradigm shift during contemporary scientific presentations and seminars. The expression was popularized by Thomas Kuhn’s book The Structure of Scientific Revolutions. In that book, Kuhn referred to ground-breaking and revolutionary changes in scientific thought as paradigm shifts, but the expression is so over-used today that [...]

March 29, 2012

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1:20 PM | Dynamic Mitochondrial Networks in Cancer

Research projects evolve in a fortuitous manner, often guided by a convergence of novel observations, intuition, helpful colleagues and unique personal circumstances. It is precisely this constellation that prompted two cardiologists to study the mitochondrial networks in lung cancer cells. In 2008, my colleague and friend Stephen Archer, a Professor of Medicine at the University [...]