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August 02, 2011

11:30 AM | All that glisters is not gold: Quality of Public Domain Chemistry Databases

Shakespeare wrote "All that glisters is not gold" and how right he was. Whether it’s the before and after shots of models who have lost an incredible 10 pounds in just two days on a particular pill, or the couch potato who showed a six pack of abs in just 2 weeks after drinking some [...]

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Marijuana and Diabetes: Does Pot Make You Thin?

Teasing out the insulin effect. On the face of it, the study seems to come out of left field: A group of researchers claimed that marijuana smokers showed 16 per cent lower fasting insulin levels than non-smokers. The study, called “The Impact of Marijuana Use on Glucose, Insulin, and Insulin Resistance among US Adults,” is in press for The American Journal of Medicine. The authors are a diverse group of medical researchers from Harvard, Beth Israel Deaconess Medical Center, and […]

Penner E.A., Buettner H. & Mittleman M.A. (2013). The Impact of Marijuana Use on Glucose, Insulin, and Insulin Resistance among US Adults, The American Journal of Medicine, DOI: 10.1016/j.amjmed.2013.03.002

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Video Tip of the Week: Canary Database for sentinels of human health

Recently we attended the Medical Library Association conference (#MLAnet13). Librarians are working so hard to wrangle information into usable forms, and to generate new connections among data types to reveal new information and leads for further studies. I ♥ librarians. In one of the sessions I attended on Medical Informatics, I heard several great talks. One [...]

Rabinowitz, P., Scotch, M. & Conti, L. (2010). Animals as Sentinels: Using Comparative Medicine To Move Beyond the Laboratory, ILAR Journal, 51 (3) 262-267. DOI: 10.1093/ilar.51.3.262

Rabinowitz, P., Gordon, Z., Holmes, R., Taylor, B., Wilcox, M., Chudnov, D., Nadkarni, P. & Dein, F. (2005). Animals as Sentinels of Human Environmental Health Hazards: An Evidence-Based Analysis, EcoHealth, 2 (1) 26-37. DOI: 10.1007/s10393-004-0151-1

Rabinowitz, P., Cullen, M. & Lake, H. (1999). Wildlife as sentinels for human health hazards: a review of study designs, Journal of Environmental Medicine, 1 (4) 217-223. DOI: 10.1002/jem.33

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Dogs can haz brainscanz and EEG?

Canine cognition is a hot topic these days, using experiments and brain imaging as research tools. The trouble with brain imaging work is that it is invasive, to the extent that animals may have to be sedated or anaesthetized for the study. All that changed with the amazing work of Gregory Berns et al and the first-ever fMRI study on awake, unrestrained dogs last year. Now Miiamaaria Kujala et al in Finland have shown that it is also possible to do a non-invasive EEG with dogs.An EEG […]

Berns, G., Brooks, A. & Spivak, M. (2012). Functional MRI in Awake Unrestrained Dogs, PLoS ONE, 7 (5) DOI: 10.1371/journal.pone.0038027

Kujala, M., Törnqvist, H., Somppi, S., Hänninen, L., Krause, C., Vainio, O. & Kujala, J. (2013). Reactivity of Dogs' Brain Oscillations to Visual Stimuli Measured with Non-Invasive Electroencephalography, PLoS ONE, 8 (5) DOI: 10.1371/journal.pone.0061818

Ma, H., Qin, L., Dong, C., Zhong, R. & Sato, Y. (2013). Comparison of Neural Responses to Cat Meows and Human Vowels in the Anterior and Posterior Auditory Field of Awake Cats, PLoS ONE, 8 (1) DOI: 10.1371/journal.pone.0052942

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Twitter versus the Grim Reaper: Extraverts but not introverts use Twitter to ward off existential anxiety

As Twitter has grown in popularity, a number of research studies have examined motivations for using this microblogging platform. A recent study drawing on the framework of Terror Management Theory, made the intriguing finding that when confronted with a reminder of one’s eventual death, extraverts increased their Twitter usage while introverts avoided it altogether. Extraverts and introverts appear to have different ways of coping with existential threats that could affect their use of […]

Qiu L, Leung AK, Ho JH, Yeung QM, Francis KJ & Chua PF (2010). Understanding the psychological motives behind microblogging., Studies in health technology and informatics, 154 140-4. PMID: 20543286

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Down in the underground, scuds lose eyes but keep genes

When animals live caves full time, their descendents often lose their eyes. It has happened over and over and over and over again, in all different kinds of animals. But how this happens is not obvious. Stephen Jay Gould wrote that some people would use cave fish as an argument that “Lamarck must have been on to something” with his idea that acquired characteristics can be inherited. Well, no, that’s not that case, but it is a good example of how tricky thinking about losses can be. The […]

Carlini D.B., Satish S. & Fong D.W. (2013). Parallel reduction in expression, but no loss of functional constraint, in two opsin paralogs within cave populations of Gammarus minus (Crustacea: Amphipoda), BMC Evolutionary Biology, 13 (1) 89. DOI: 10.1186/1471-2148-13-89

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August 02, 2011

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