Research published in March 2012 showed differences in the genetics of kidney cancers within the same patients – and even within the same tumours. Now research from Dana-Farber Cancer Institute and the Broad Institute has shown that the genetic profiles of chronic lymphocytic leukaemia (CLL) also shift and change, allowing a glimpse into the past, present and future of the cancer. the results are published in Cell.
Landau, D., Carter, S., Stojanov, P., McKenna, A., Stevenson, K., Lawrence, M., Sougnez, C., Stewart, C., Sivachenko, A., Wang, L. & Wan, Y. (2013). Evolution and Impact of Subclonal Mutations in Chronic Lymphocytic Leukemia, Cell, 152 (4) 714-726. DOI: 10.1016/j.cell.2013.01.019