Epidemiology is always valuable for generating hypotheses based on statistical associations. However, statistical relationships do not characterize cause and care must be taken when teasing out the relative contribution of different factors.Case in point, Nguyen and colleagues analyzed measures of cognitive function in 5,635 children (6-16 years) and serum folate and vitamin B12 concentrations collected from 1988-1994, before mandatory folate fortification of grains. Mean folate and vitamin B12 […]
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