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10:47 PM | January 22, 2013
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And now, the final step in how to build your computational model of a neuron: Add Synaptic Channels. All the steps in this series can be found here.Synapses connect neurons (source)So you already have a neuron, and you've added intrinsic channels to it. The next thing you want to do is add synaptic channels so you can hook this neuron up to other cells.The main synaptic channels you want to add are the excitatory channels: NMDA and AMPA and the inhibitory channel GABA. These channels don't have […]

Evans RC, Morera-Herreras T, Cui Y, Du K, Sheehan T, Kotaleski JH, Venance L & Blackwell KT (2012). The effects of NMDA subunit composition on calcium influx and spike timing-dependent plasticity in striatal medium spiny neurons., PLoS computational biology, 8 (4) PMID:

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