Dr. Matt Petroski and colleagues outline a new method to test a tumor’s resistance to an experimental therapy and pinpoint the genetic culprit before testing the drug in patients—providing a new path toward personalized medicine.
Toth JI, Yang L, Dahl R & Petroski MD (2012). A gatekeeper residue for NEDD8-activating enzyme inhibition by MLN4924., Cell reports, 1 (4) 309-16. PMID: 22832224
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